Nature

Hydatellaceae identified as a new branch near the base of the angiosperm phylogenetic tree.

Saarela, Rai, Doyle, Endress, Mathews, Marchant, Briggs, Graham; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Key collaborators.

none; (JOURNAL ARTICLE)

Making the paper: Tobias Brixner.

none; (JOURNAL ARTICLE)

Botany: new home for tiny aquatics.

Friis, Crane; (Comment, News)

News in brief.

none; (JOURNAL ARTICLE)

Theoretical chemistry: the six-bond bound.

Frenking, Tonner; (News)

Solar system: portrait of a suburban family.

Morbidelli; (Comment, News)

The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production.

Pastorino, Sun, Lu, Zhou, Balastik, Finn, Wulf, Lim, Li, Li, Xia, Nicholson, Lu; (JOURNAL ARTICLE)

Research highlights.

none; (JOURNAL ARTICLE)

Open for business.

none; (Editorial)

Linnaeus in the information age.

Godfray; (Journal Article)

Epithelial NEMO links innate immunity to chronic intestinal inflammation.

Nenci, Becker, Wullaert, Gareus, van Loo, Danese, Huth, Nikolaev, Neufert, Madison, Gumucio, Neurath, Pasparakis; (JOURNAL ARTICLE)

Seed money to bring in pioneers.

Check; (News)

The legacy of Linnaeus.

none; (Editorial)

Physical chemistry: the peripatetic proton.

Hynes; (News)

Linnaeus at 300: the royal raccoon from Swedesboro.

Nicholls; (News)

Half-metallic graphene nanoribbons.

Son, Cohen, Louie; (JOURNAL ARTICLE)

Evolution and diversity of subduction zones controlled by slab width.

Schellart, Freeman, Stegman, Moresi, May; (Journal Article)

Abstractions.

none; (JOURNAL ARTICLE)

Correction.

none; (JOURNAL ARTICLE)

Hybrid speciation.

Mallet; (Journal Article, Research Support, Non-U.S. Gov't)

Sidelines.

none; (JOURNAL ARTICLE)

Washington, we have a problem.

Goldston; (Journal Article)

Microbes reveal extent of biodiversity.

Ledford; (News)

Faulty logic.

May; (JOURNAL ARTICLE)

Quantum physics: total surveillance.

Schmidt-Kaler; (Comment, News)

Human embryonic stem cell lines derived from single blastomeres.

Klimanskaya, Chung, Becker, Lu, Lanza; (JOURNAL ARTICLE)

Linnaeus at 300: we are family.

Whitfield; (News)

Cell biology: lost in mitotic translation.

Wynshaw-Boris; (Comment, News)

A collisional family of icy objects in the Kuiper belt.

Brown, Barkume, Ragozzine, Schaller; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Geophysicist faces probe into use of research funds.

Giles; (News)

Quantum jumps of light recording the birth and death of a photon in a cavity.

Gleyzes, Kuhr, Guerlin, Bernu, Deléglise, Busk Hoff, Brune, Raimond, Haroche; (Journal Article, Research Support, Non-U.S. Gov't)

Linnaeus at 300: the big name hunters.

Borrell; (News)

A Hedgehog- and Antennapedia-dependent niche maintains Drosophila haematopoietic precursors.

Mandal, Martinez-Agosto, Evans, Hartenstein, Banerjee; (Journal Article, Research Support, N.I.H., Extramural)

Linnaeus at 300: the species and the specious.

Marris; (News)

Adaptive subwavelength control of nano-optical fields.

Aeschlimann, Bauer, Bayer, Brixner, García de Abajo, Pfeiffer, Rohmer, Spindler, Steeb; (Journal Article, Research Support, Non-U.S. Gov't)

Biological programming.

Adami; (JOURNAL ARTICLE)

Control of blood cell homeostasis in Drosophila larvae by the posterior signalling centre.

KrzemieÅ„, Dubois, Makki, Meister, Vincent, Crozatier; (Journal Article, Research Support, Non-U.S. Gov't)

Concept of a bacterium still valid in prokaryote debate.

Cavalier-Smith; (Comment, Letter)

Quantum leap of faith.

Brumfiel; (Journal Article)

Spreading the word.

Knapp, Polaszek, Watson; (Journal Article)

Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner.

Galburt, Grill, Wiedmann, Lubkowska, Choy, Nogales, Kashlev, Bustamante; (JOURNAL ARTICLE)

The structure of consciousness.

Buzsáki; (Journal Article)

Mysteries of female anatomy.

Knoeff; (JOURNAL ARTICLE)

In praise of the 'brain drain'.

none; (Editorial)

The receptors and coding logic for bitter taste.

Mueller, Hoon, Erlenbach, Chandrashekar, Zuker, Ryba; (JOURNAL ARTICLE)

Count on it.

Gewin; (Journal Article)

Scientists need to confront economists about peak oil.

Lardelli; (Comment, Letter)

Bush challenged on funding for children's study.

Wadman; (News)

Non-volcanic tremor and low-frequency earthquake swarms.

Shelly, Beroza, Ide; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements.

Lareau, Inada, Green, Wengrod, Brenner; (JOURNAL ARTICLE)

A new eutriconodont mammal and evolutionary development in early mammals.

Luo, Chen, Li, Chen; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Happy centenary, photon.

Zeilinger, Weihs, Jennewein, Aspelmeyer; (JOURNAL ARTICLE)

Plant taxonomy: The love of plants.

Müller-Wille; (Journal Article)

Mammals on the move.

Kielan-Jaworowska; (JOURNAL ARTICLE)

The molecular choreography of a store-operated calcium channel.

Lewis; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Superconductors: unusual oxygen isotope effects in cuprates?

Douglas, Iwasawa, Sun, Fedorov, Ishikado, Saitoh, Eisaki, Bando, Iwase, Ino, Arita, Shimada, Namatame, Taniguchi, Masui, Tajima, Fujita, Uchida, Aiura, Dessau; (Comment, Journal Article)

Q&A:Klaus Töpfer.

none; (News)

50 & 100 Years Ago.

none; (JOURNAL ARTICLE)

Passive-smoking study faces review.

Dalton; (News)

Publications should include an animal-welfare section.

Würbel; (Comment, Letter)

14-3-3sigma controls mitotic translation to facilitate cytokinesis.

Wilker, van Vugt, Artim, Huang, Petersen, Reinhardt, Feng, Sharp, Sonenberg, White, Yaffe; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Science

Climate change. Why is it hard to predict the future of ice sheets?

Vaughan, Arthern; (Journal Article)

AIDS/HIV. Finding footprints among the trees.

Klenerman, McMichael; (Comment, Journal Article)

The latitudinal gradient in recent speciation and extinction rates of birds and mammals.

Weir, Schluter; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Education research. U.S. math tests don't line up.

Mervis; (News)

The uncertain future of research chimpanzees.

Varki; (Comment, Letter)

The evolutionary demography of ecological change: linking trait variation and population growth.

Pelletier, Clutton-Brock, Pemberton, Tuljapurkar, Coulson; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

A Closer Look at a Gamma-Ray Burst.

Covino; (JOURNAL ARTICLE)

Lunar science. Taking a stern look at NASA science.

Lawler; (News)

Arctic air pollution: origins and impacts.

Law, Stohl; (Journal Article, Research Support, Non-U.S. Gov't)

Celebrating polar science.

Leshner; (Editorial)

Promotion of Lymphocyte Egress into Blood and Lymph by Distinct Sources of Sphingosine-1-Phosphate.

Pappu, Schwab, Cornelissen, Pereira, Regard, Xu, Camerer, Zheng, Huang, Cyster, Coughlin; (JOURNAL ARTICLE)

Keep astrobiology funding alive.

Molholt; (Comment, Letter)

Physics. Critical Insights.

Altman; (Comment, Journal Article)

Climate change. Rethinking ice sheet time scales.

Truffer, Fahnestock; (Comment, Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Cancer research. Budget pressure puts high-profile study in doubt.

Marshall; (News)

IPY means doing what it takes to get to the ends of the Earth.

Mervis; (News)

Strong Association of De Novo Copy Number Mutations with Autism.

Sebat, Lakshmi, Malhotra, Troge, Lese-Martin, Walsh, Yamrom, Yamrom, Yoon, Krasnitz, Kendall, Leotta, Pai, Zhang, Lee, Hicks, Spence, Lee, Puura, Lehtimäki, Ledbetter, Gregersen, Bregman, Sutcliffe, Jobanputra, Chung, Warburton, King, Skuse, Geschwind, Gilliam, Ye, Wigler; (JOURNAL ARTICLE)

Carbon emissions. Report backs more projects to sequester CO2 from coal.

Kintisch; (News)

Thriving Arctic bottom dwellers could get strangled by warming.

Krajick; (News)

Space science. NASA declares no room for antimatter experiment.

Lawler; (News)

A cytochrome C oxidase model catalyzes oxygen to water reduction under rate-limiting electron flux.

Collman, Devaraj, Decréau, Yang, Yan, Ebina, Eberspacher, Chidsey; (Journal Article, Research Support, N.I.H., Extramural)

Critical behavior of a trapped interacting Bose gas.

Donner, Ritter, Bourdel, Ottl, Köhl, Esslinger; (Journal Article, Research Support, Non-U.S. Gov't)

Perspectives on the Arctic's shrinking sea-ice cover.

Serreze, Holland, Stroeve; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Long (and perilous) march heralds China's rise as polar research power.

Stone; (News)

Lunar science. Asking for the Moon.

Lawler; (News)

Structural biology. A glimpse of biology's first enzyme.

Joyce; (Comment, Journal Article)

Conformationally controlled chemistry: excited-state dynamics dictate ground-state reaction.

Kim, Shen, Tao, Martinez, Suits; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Cellulosic ethanol. Biofuel researchers prepare to reap a new harvest.

Service; (News)

Attention-like processes in Drosophila require short-term memory genes.

van Swinderen; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Development. Built to run, not fail.

Oliveri, Davidson; (Journal Article, Research Support, N.I.H., Extramural)

Comment on "Global genetic change tracks global climate warming in Drosophila subobscura".

Rodríguez-Trelles, Rodríguez; (Comment, Journal Article, Research Support, Non-U.S. Gov't)

Polar science. Sailing the southern sea.

Bohannon; (News)

Long-term satellite record reveals likely recent aerosol trend.

Mishchenko, Geogdzhayev, Rossow, Cairns, Carlson, Lacis, Liu, Travis; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Boom and bust in a polar hot zone.

Stokstad; (News)

Momentous Changes at the Poles.

Pennisi, Smith, Stone; (JOURNAL ARTICLE)

Metagenomics. Ocean study yields a tidal wave of microbial DNA.

Bohannon; (News)

Subsurface Radar Sounding of the South Polar Layered Deposits of Mars.

Plaut, Picardi, Safaeinili, Ivanov, Milkovich, Cicchetti, Kofman, Mouginot, Farrell, Phillips, Clifford, Frigeri, Orosei, Federico, Williams, Gurnett, Nielsen, Hagfors, Heggy, Stofan, Plettemeier, Watters, Leuschen, Edenhofer; (JOURNAL ARTICLE)

For extreme astronomy, head due south.

Clery; (News)

Recent sea-level contributions of the Antarctic and Greenland ice sheets.

Shepherd, Wingham; (Journal Article)

Public health. Return of the population growth factor.

Campbell, Cleland, Ezeh, Prata; (Journal Article)

Ivory-billed or pileated woodpecker?

Sibley, Bevier, Patten, Elphick; (Comment, Letter)

Archaeology. German law stirs concern illegal artifacts will be easier to sell.

Curry; (News)

Polar science. Race to plumb the frigid depths.

Krajick; (News)

Early Optical Polarization of a Gamma-Ray Burst Afterglow.

Mundell, Steele, Smith, Kobayashi, Melandri, Guidorzi, Gomboc, Mottram, Clarke, Monfardini, Carter, Bersier; (JOURNAL ARTICLE)

The structural basis of ribozyme-catalyzed RNA assembly.

Robertson, Scott; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Climate change. Is a thinning haze unveiling the real global warming?

Kerr; (Comment, News)

Resonant amplification of magnetic domain-wall motion by a train of current pulses.

Thomas, Hayashi, Jiang, Moriya, Rettner, Parkin; (Journal Article)

Polar science. Opening doors to native knowledge.

Couzin; (News)

Founder effects in the assessment of HIV polymorphisms and HLA allele associations.

Bhattacharya, Daniels, Heckerman, Foley, Frahm, Kadie, Carlson, Yusim, McMahon, Gaschen, Mallal, Mullins, Nickle, Herbeck, Rousseau, Learn, Miura, Brander, Walker, Korber; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Nature Methods

Unitary permeability of gap junction channels to second messengers measured by FRET microscopy.

Hernandez, Bortolozzi, Pertegato, Beltramello, Giarin, Zaccolo, Pantano, Mammano; (JOURNAL ARTICLE)

Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies.

Kittler, Surendranath, Heninger, Slabicki, Theis, Putz, Franke, Caldarelli, Grabner, Kozak, Wagner, Rees, Korn, Frenzel, Sachse, Sönnichsen, Guo, Schelter, Burchard, Linsley, Jackson, Habermann, Buchholz; (JOURNAL ARTICLE)

Fluorescence imaging of amyloid formation in living cells by a functional, tetracysteine-tagged alpha-synuclein.

Roberti, Bertoncini, Klement, Jares-Erijman, Jovin; (JOURNAL ARTICLE)

Nature Biotechnology

An expression atlas of rice mRNAs and small RNAs.

Nobuta, Venu, Lu, Bélo, Vemaraju, Kulkarni, Wang, Pillay, Green, Wang, Meyers; (JOURNAL ARTICLE)

Reporter proteins for in vivo fluorescence without oxygen.

Drepper, Eggert, Circolone, Heck, Krauß, Guterl, Wendorff, Losi, Gärtner, Jaeger; (JOURNAL ARTICLE)

Nature Medicine

MRI detection of transcriptional regulation of gene expression in transgenic mice.

Cohen, Ziv, Plaks, Israely, Kalchenko, Harmelin, Benjamin, Neeman; (JOURNAL ARTICLE)

Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease.

Lee, Jeyakumar, Gonzalez, Takahashi, Lee, Baek, Clark, Rose, Fu, Clarke, McKercher, Meerloo, Muller, Park, Butters, Dwek, Schwartz, Tong, Wenger, Lipton, Seyfried, Platt, Snyder; (JOURNAL ARTICLE)

Molecular imaging of VEGF receptors in angiogenic vasculature with single-chain VEGF-based probes.

Backer, Levashova, Patel, Jehning, Claffey, Blankenberg, Backer; (JOURNAL ARTICLE)

Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease.

Khoury, Toft, Hickman, Means, Terada, Geula, Luster; (JOURNAL ARTICLE)

Bone marrow-specific Cap gene deletion protects against high-fat diet-induced insulin resistance.

Lesniewski, Hosch, Neels, de Luca, Pashmforoush, Lumeng, Chiang, Scadeng, Saltiel, Olefsky; (JOURNAL ARTICLE)

Nature Genetics

The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast.

Menne, Goyenechea, Sánchez-Puig, Wong, Tonkin, Ancliff, Brost, Costanzo, Boone, Warren; (JOURNAL ARTICLE)

Homozygous silencing of T-box transcription factor EOMES leads to microcephaly with polymicrogyria and corpus callosum agenesis.

Baala, Briault, Etchevers, Laumonnier, Natiq, Amiel, Boddaert, Picard, Sbiti, Asermouh, Attié-Bitach, Encha-Razavi, Munnich, Sefiani, Lyonnet; (JOURNAL ARTICLE)

Genome-wide functional analysis of pathogenicity genes in the rice blast fungus.

Jeon, Park, Chi, Choi, Park, Rho, Kim, Goh, Yoo, Choi, Park, Yi, Yang, Kwon, Han, Kim, Khang, Park, Lim, Jung, Kong, Karunakaran, Oh, Kim, Kim, Park, Kang, Choi, Kang, Lee; (JOURNAL ARTICLE)

Stepwise replication identifies a low-producing lymphotoxin-alpha allele as a major risk factor for early-onset leprosy.

Alcaïs, Alter, Antoni, Orlova, Thuc, Singh, Vanderborght, Katoch, Mira, Thai, Huong, Ba, Moraes, Mehra, Schurr, Abel; (JOURNAL ARTICLE)

Molecular Medicine

Proteomics

The primary structure of a low-M(r) multiphosphorylated variant of beta-casein in equine milk.

Miclo, Girardet, Egito, Mollé, Martin, Gaillard; (JOURNAL ARTICLE)

Contamination of nuclear fractions with plasma membrane lipid rafts.

Say, Hooper; (JOURNAL ARTICLE)

A comprehensive proteome map of the lipid-requiring nosocomial pathogen Corynebacterium jeikeium K411.

Hansmeier, Chao, Daschkey, Müsken, Kalinowski, Pühler, Tauch; (JOURNAL ARTICLE)

Antigen discovery: A postgenomic approach to paratuberculosis diagnosis.

Leroy, Roupie, Noël-Georis, Rosseels, Walravens, Govaerts, Huygen, Wattiez; (JOURNAL ARTICLE)

Discovering robust protein biomarkers for disease from relative expression reversals in 2-D DIGE data.

Anderson, Tchernyshyov, Diez, Cole, Geman, Dang, Winslow; (JOURNAL ARTICLE)

Comprehensive yeast proteome analysis using a capillary isoelectric focusing-based multidimensional separation platform coupled with ESI-MS/MS.

Wang, Guo, Song, Lee, Balgley; (JOURNAL ARTICLE)

Proteomic characterization of copper stress response in Cannabis sativa roots.

Bona, Marsano, Cavaletto, Berta; (JOURNAL ARTICLE)

Phanerochaete chrysosporium soluble proteome as a prelude for the analysis of heavy metal stress response.

Ozcan, YÄ±ldÄ±rÄ±m, Kaya, Albrecht, Becher, Hecker, Ozcengiz; (JOURNAL ARTICLE)

Methods for the purification of ubiquitinated Proteins.

Tomlinson, Palaniyappan, Tooth, Layfield; (JOURNAL ARTICLE)

Proteomic analysis of Burkholderia cepacia MBA4 in the degradation of monochloroacetate.

Kwok, Siu, Ngai, Che, Tsang; (JOURNAL ARTICLE)

From the genome sequence to the proteome and back: Evaluation of E. coli genome annotation with a 2-D gel-based proteomics approach.

Maillet, Berndt, Malo, Rodriguez, Brunisholz, Pragai, Arnold, Langen, Wyss; (JOURNAL ARTICLE)

Protein expression profile in the striatum of rats with methamphetamine-induced behavioral sensitization.

Iwazaki, McGregor, Matsumoto; (JOURNAL ARTICLE)

2-DE analysis of a new human cell line EM-G3 derived from breast cancer progenitor cells and comparison with normal mammary epithelial cells.

SelicharovÃ¡, SmutnÃ¡, Sanda, Ubik, MatouÅ¡kovÃ¡, BurÅ¡ÃkovÃ¡, BroÅ¾ovÃ¡, Vydra, JirÃ¡Äek; (JOURNAL ARTICLE)

Detection of transient protein-protein interactions by bimolecular fluorescence complementation: The Abl-SH3 case.

Morell, Espargaró, Avilés, Ventura; (JOURNAL ARTICLE)

Proteome changes associated with hippocampal MRI abnormalities in the lithium pilocarpine-induced model of convulsive status epilepticus.

Greene, Bamidele, Choy, de Castro, Wait, Leung, Begum, Gadian, Scott, Lythgoe; (JOURNAL ARTICLE)

Yeast proteome map (update 2006).

Perrot, Guieysse-Peugeot, Massoni, Espagne, Claverol, Silva, Jenö, Santos, Bonneu, Boucherie; (JOURNAL ARTICLE)

Nature Drug Discovery

BMC Bioinformatics

Regulation of metabolic networks by small molecule metabolites.

Gutteridge, Kanehisa, Goto; (JOURNAL ARTICLE)

GeneBins: a database for classifying gene expression data, with application to plant genome arrays.

Goffard, Weiller; (JOURNAL ARTICLE)

Non-coding sequence retrieval system for comparative genomic analysis of gene regulatory elements.

Doh, Zhang, Temple, Cai; (JOURNAL ARTICLE)

Normalization method for metabolomics data using optimal selection of multiple internal standards.

Sysi-Aho, Katajamaa, Yetukuri, Oresic; (JOURNAL ARTICLE)

Fast computation of distance estimators.

Elias, Lagergren; (JOURNAL ARTICLE)

Model based analysis of real-time PCR data from DNA binding dye protocols.

Alvarez, Vila-Ortiz, Salibe, Podhajcer, Pitossi; (JOURNAL ARTICLE)

Towards a comprehensive structural coverage of foldspace: A structural genomics viewpoint.

Marsden, Lewis, Orengo; (JOURNAL ARTICLE)

Importance of data structure in comparing two dimension reduction methods for classification of microarray gene expression data.

Truntzer, Mercier, Esteve, Gautier, Roy; (JOURNAL ARTICLE)

Discarding duplicate ditags in LongSAGE analysis may introduce significant error.

Emmersen, Heidenblut, Laursen Hogh, Hahn, Welinder, Nielsen; (JOURNAL ARTICLE)

Modeling human cancer-related regulatory modules by GA-RNN hybrid algorithms.

Chiang, Chao; (JOURNAL ARTICLE)

Bioinformatics

Discovery of microRNA-mRNA modules via population-based probabilistic learning.

Joung, Hwang, Nam, Kim, Zhang; (JOURNAL ARTICLE)

Proc Natl Acad Sci U S A

Large seasonal swings in leaf area of Amazon rainforests.

Myneni, Yang, Nemani, Huete, Dickinson, Knyazikhin, Didan, Fu, Negrón Juárez, Saatchi, Hashimoto, Ichii, Shabanov, Tan, Ratana, Privette, Morisette, Vermote, Roy, Wolfe, Friedl, Running, Votava, El-Saleous, Devadiga, Su, Salomonson; (JOURNAL ARTICLE)

A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug efflux pumps.

Lobedanz, Bokma, Symmons, Koronakis, Hughes, Koronakis; (Journal Article)

Impaired NFAT nuclear translocation results in split exhaustion of virus-specific CD8+ T cell functions during chronic viral infection.

Agnellini, Wolint, Rehr, Cahenzli, Karrer, Oxenius; (Journal Article)

Loss of Aire-dependent thymic expression of a peripheral tissue antigen renders it a target of autoimmunity.

Gavanescu, Kessler, Ploegh, Benoist, Mathis; (Journal Article)

KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging.

Ocorr, Reeves, Wessells, Fink, Chen, Akasaka, Yasuda, Metzger, Giles, Posakony, Bodmer; (Journal Article)

DgrA is a member of a new family of cyclic diguanosine monophosphate receptors and controls flagellar motor function in Caulobacter crescentus.

Christen, Christen, Allan, Folcher, Jenö, Grzesiek, Jenal; (Journal Article)

DNA barcoding and the renaissance of taxonomy.

Miller; (JOURNAL ARTICLE)

Restriction of endogenous T cell antigen receptor beta rearrangements to Vbeta14 through selective recombination signal sequence modifications.

Wu, Ranganath, Gleason, Woodman, Borjeson, Alt, Bassing; (Journal Article)

C-type natriuretic peptide regulates blood-testis barrier dynamics in adult rat testes.

Xia, Mruk, Cheng; (Journal Article)

Cellular scaling rules for primate brains.

Herculano-Houzel, Collins, Wong, Kaas; (Journal Article)

An optimized transgenesis system for Drosophila using germ-line-specific {varphi}C31 integrases.

Bischof, Maeda, Hediger, Karch, Basler; (Journal Article)

From the Cover: Structure of the Parkin in-between-ring domain provides insights for E3-ligase dysfunction in autosomal recessive Parkinson's disease.

Beasley, Hristova, Shaw; (Journal Article)

Stable masking by H-2Dd cis ligand limits Ly49A relocalization to the site of NK cell/target cell contact.

Back, Chalifour, Scarpellino, Held; (Journal Article)

Functional, fractal nonlinear response with application to rate processes with memory, allometry, and population genetics.

Vlad, Morán, Popa, Szedlacsek, Ross; (JOURNAL ARTICLE)

From the Cover: Increased genetic variation and evolutionary potential drive the success of an invasive grass.

Lavergne, Molofsky; (Journal Article)

Division and differentiation of natural antibody-producing cells in mouse spleen.

Yang, Tung, Ghosn, Herzenberg, Herzenberg; (Journal Article)

Spatial navigation deficit in amnestic mild cognitive impairment.

Hort, Laczó, Vyhnálek, Bojar, Bures, Vlcek; (Journal Article)

Systemic inflammation and neurodegeneration in a mouse model of multiple sulfatase deficiency.

Settembre, Annunziata, Spampanato, Zarcone, Cobellis, Nusco, Zito, Tacchetti, Cosma, Ballabio; (Journal Article)

An Andean origin of Phytophthora infestans inferred from mitochondrial and nuclear gene genealogies.

Gómez-Alpizar, Carbone, Ristaino; (Journal Article)

Prefrontal/accumbal catecholamine system determines motivational salience attribution to both reward- and aversion-related stimuli.

Ventura, Morrone, Puglisi-Allegra; (JOURNAL ARTICLE)

The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease.

Höglinger, Breunig, Depboylu, Rouaux, Michel, Alvarez-Fischer, Boutillier, Degregori, Oertel, Rakic, Hirsch, Hunot; (Journal Article)

Attenuated virulence of a Francisella mutant lacking the lipid A 4'-phosphatase.

Wang, Ribeiro, Guan, Abraham, Raetz; (Journal Article)

Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling.

Jain, Petzold, Schelle, Leavell, Mougous, Bertozzi, Leary, Cox; (JOURNAL ARTICLE)

Nature of hydrogen interactions with Ni(II) complexes containing cyclic phosphine ligands with pendant nitrogen bases.

Wilson, Shoemaker, Miedaner, Muckerman, Dubois, Rakowski Dubois; (JOURNAL ARTICLE)

Collective neuronal growth and self organization of axons.

de Gennes; (JOURNAL ARTICLE)

Adhesion mechanisms of the mussel foot proteins mfp-1 and mfp-3.

Lin, Gourdon, Sun, Holten-Andersen, Anderson, Waite, Israelachvili; (Journal Article)

HIV-1 gp120 inhibits TLR9-mediated activation and IFN-{alpha} secretion in plasmacytoid dendritic cells.

Martinelli, Cicala, Van Ryk, Goode, Macleod, Arthos, Fauci; (Journal Article)

In vitro analysis of DNA-protein interactions by proximity ligation.

Gustafsdottir, Schlingemann, Rada-Iglesias, Schallmeiner, Kamali-Moghaddam, Wadelius, Landegren; (Journal Article)

c-Myc-mediated genomic instability proceeds via a megakaryocytic endomitosis pathway involving Gp1b{alpha}.

Li, Lu, Prochownik; (Journal Article)

Intersubunit movement is required for ribosomal translocation.

Horan, Noller; (JOURNAL ARTICLE)

Meiosis in living color: Fluorescence-based tetrad analysis in Arabidopsis.

Hawley; (Journal Article)

Selective retention of herpes simplex virus-specific T cells in latently infected human trigeminal ganglia.

Verjans, Hintzen, van Dun, Poot, Milikan, Laman, Langerak, Kinchington, Osterhaus; (Journal Article)

Cerebellar GABAergic progenitors adopt an external granule cell-like phenotype in the absence of Ptf1a transcription factor expression.

Pascual, Abasolo, Mingorance-Le Meur, Martínez, Del Rio, Wright, Real, Soriano; (JOURNAL ARTICLE)

A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors.

Scott, Lee, Tebbutt, Herbertson, Gill, Liu, Skrinos, Murone, Saunder, Chappell, Papenfuss, Poon, Hopkins, Smyth, Macgregor, Cher, Jungbluth, Brechbiel, Murphy, Burgess, Hoffman, Johns, Old; (Journal Article)

From the Cover: Folate biofortification of tomato fruit.

Díaz de la Garza, Gregory, Hanson; (Journal Article)

Spiral structure of Escherichia coli HU{alpha}beta provides foundation for DNA supercoiling.

Guo, Adhya; (Journal Article)

Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas.

Price, Trent, El-Naggar, Cogdell, Taylor, Hunt, Pollock, Hood, Shmulevich, Zhang; (Journal Article)

Complex larval connectivity patterns among marine invertebrate populations.

Becker, Levin, Fodrie, McMillan; (Journal Article)

Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis.

Yuan, Barrett, Zhang, Kahne, Sliz, Walker; (JOURNAL ARTICLE)

Evidence for a dual binding mode of dockerin modules to cohesins.

Carvalho, Dias, Nagy, Prates, Proctor, Smith, Bayer, Davies, Ferreira, Romão, Fontes, Gilbert; (Journal Article)

Differential responses of hippocampal subfields to cortical up-down states.

Hahn, Sakmann, Mehta; (JOURNAL ARTICLE)

Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.

Zhou, Tian, Sandzén, Cao, Flaberg, Szekely, Cao, Ohlsson, Bergo, Borén, Akyürek; (JOURNAL ARTICLE)

Studies of nucleotide binding to the catalytic sites of Escherichia coli betaY331W-F1-ATPase using fluorescence quenching.

Bulygin, Milgrom; (Journal Article)

Tradeoffs between income, biodiversity, and ecosystem functioning during tropical rainforest conversion and agroforestry intensification.

Steffan-Dewenter, Kessler, Barkmann, Bos, Buchori, Erasmi, Faust, Gerold, Glenk, Gradstein, Guhardja, Harteveld, Hertel, Höhn, Kappas, Köhler, Leuschner, Maertens, Marggraf, Migge-Kleian, Mogea, Pitopang, Schaefer, Schwarze, Sporn, Steingrebe, Tjitrosoedirdjo, Tjitrosoemito, Twele, Weber, Woltmann, Zeller, Tscharntke; (JOURNAL ARTICLE)

The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia.

Carrière, Seeley, Goetze, Longnecker, Korc; (Journal Article)

A coherent neurobiological framework for functional neuroimaging provided by a model integrating compartmentalized energy metabolism.

Aubert, Pellerin, Magistretti, Costalat; (Journal Article)

{alpha}-Lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway.

Zhang, Wei, Hagen, Frei; (Journal Article)

Functional and morphometric brain dissociation between dyslexia and reading ability.

Hoeft, Meyler, Hernandez, Juel, Taylor-Hill, Martindale, McMillon, Kolchugina, Black, Faizi, Deutsch, Siok, Reiss, Whitfield-Gabrieli, Gabrieli; (Journal Article)

Cross-talk between Chk1 and Chk2 in double-mutant thymocytes.

Zaugg, Su, Reilly, Moolani, Cheung, Hakem, Hirao, Elledge, Mak; (Journal Article)

Global molecular phylogeography reveals persistent Arctic circumpolar isolation in a marine planktonic protist.

Darling, Kucera, Wade; (JOURNAL ARTICLE)

Accumulation of prion protein in the brain that is not associated with transmissible disease.

Piccardo, Manson, King, Ghetti, Barron; (Journal Article)

Optimizing the control of disease infestations at the landscape scale.

Forster, Gilligan; (JOURNAL ARTICLE)

Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand.

Armbruster, Li, Pausch, Herlitze, Roth; (JOURNAL ARTICLE)

From the Cover: Prospects for fungus identification using CO1 DNA barcodes, with Penicillium as a test case.

Seifert, Samson, Dewaard, Houbraken, Lévesque, Moncalvo, Louis-Seize, Hebert; (Journal Article)

Single-site mutations in the carboxyltransferase domain of plastid acetyl-CoA carboxylase confer resistance to grass-specific herbicides.

Liu, Harrison, Chalupska, Gornicki, O'donnell, Adkins, Haselkorn, Williams; (Journal Article)

Differential binding of calmodulin-related proteins to their targets revealed through high-density Arabidopsis protein microarrays.

Popescu, Popescu, Bachan, Zhang, Seay, Gerstein, Snyder, Dinesh-Kumar; (Journal Article)

Structural characterization of the fission yeast U5.U2/U6 spliceosome complex.

Ohi, Ren, Wall, Gould, Walz; (Journal Article)

Targeted deletion of Wwox reveals a tumor suppressor function.

Aqeilan, Trapasso, Hussain, Costinean, Marshall, Pekarsky, Hagan, Zanesi, Kaou, Stein, Lian, Croce; (Journal Article)

Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations.

Georgitsi, Raitila, Karhu, Tuppurainen, Mäkinen, Vierimaa, Paschke, Saeger, van der Luijt, Sane, Robledo, De Menis, Weil, Wasik, Zielinski, Lucewicz, Lubinski, Launonen, Vahteristo, Aaltonen; (Journal Article)

Mechanism of metal-independent decomposition of organic hydroperoxides and formation of alkoxyl radicals by halogenated quinones.

Zhu, Zhao, Kalyanaraman, Liu, Shan, Du, Frei; (Journal Article)

NF-{kappa}B activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.

Miggin, Pålsson-McDermott, Dunne, Jefferies, Pinteaux, Banahan, Murphy, Moynagh, Yamamoto, Akira, Rothwell, Golenbock, Fitzgerald, O'neill; (Journal Article)

Paradoxical influence of hippocampal neurogenesis on working memory.

Saxe, Malleret, Vronskaya, Mendez, Garcia, Sofroniew, Kandel, Hen; (Journal Article)

Absence of the proapoptotic Bax protein extends fertility and alleviates age-related health complications in female mice.

Perez, Jurisicova, Wise, Lipina, Kanisek, Bechard, Takai, Hunt, Roder, Grynpas, Tilly; (JOURNAL ARTICLE)

Defective glycerol metabolism in aquaporin 9 (AQP9) knockout mice.

Rojek, Skowronski, Füchtbauer, Füchtbauer, Fenton, Agre, Frøkiær, Nielsen; (JOURNAL ARTICLE)

Activation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells.

Sherwood, Prior, Voronina, Barrow, Woodsmith, Gerasimenko, Petersen, Tepikin; (JOURNAL ARTICLE)

Regulation of carbon and nitrogen metabolism: Adding regulation of ion channels and another second messenger to the mix.

Ninfa; (Journal Article)

Loss of muscle-specific RING-finger 3 predisposes the heart to cardiac rupture after myocardial infarction.

Fielitz, van Rooij, Spencer, Shelton, Latif, van der Nagel, Bezprozvannaya, de Windt, Richardson, Bassel-Duby, Olson; (Journal Article)

Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases.

Castro, Smidansky, Maksimchuk, Arnold, Korneeva, Götte, Konigsberg, Cameron; (Journal Article)

From the Cover: Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia.

Yamada, Gerber, Iwayama, Ohnishi, Ohba, Toyota, Aruga, Minabe, Tonegawa, Yoshikawa; (Journal Article)

A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells.

Cao, Capell, Erdos, Djabali, Collins; (JOURNAL ARTICLE)

Developmental and adult phenotyping directly from mutant embryonic stem cells.

George, Gertsenstein, Vintersten, Korets-Smith, Murphy, Stevens, Haigh, Nagy; (Journal Article)

Structure of the N-terminal domain of a type B1 G protein-coupled receptor in complex with a peptide ligand.

Grace, Perrin, Gulyas, Digruccio, Cantle, Rivier, Vale, Riek; (JOURNAL ARTICLE)

Mycobacterium tuberculosis produces pili during human infection.

Alteri, Xicohténcatl-Cortes, Hess, Caballero-Olín, Girón, Friedman; (JOURNAL ARTICLE)

Interaction with the mammary microenvironment redirects spermatogenic cell fate in vivo.

Boulanger, Mack, Booth, Smith; (Journal Article)

Global extent of horizontal gene transfer.

Choi, Kim; (Journal Article)

WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo.

Ring, Cheng, Leng, Kahle, Rinehart, Lalioti, Volkman, Wilson, Hebert, Lifton; (Journal Article)

Bound anionic states of adenine.

Haranczyk, Gutowski, Li, Bowen; (JOURNAL ARTICLE)

DNA barcodes affirm that 16 species of apparently generalist tropical parasitoid flies (Diptera, Tachinidae) are not all generalists.

Smith, Wood, Janzen, Hallwachs, Hebert; (JOURNAL ARTICLE)

Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.

Davidovich, Bashan, Auerbach-Nevo, Yaggie, Gontarek, Yonath; (Journal Article)

EDEM1 reveals a quality control vesicular transport pathway out of the endoplasmic reticulum not involving the COPII exit sites.

Zuber, Cormier, Guhl, Santimaria, Hebert, Roth; (Journal Article)

Divergent functions of VTI12 and VTI11 in trafficking to storage and lytic vacuoles in Arabidopsis.

Sanmartín, Ordóñez, Sohn, Robert, Sánchez-Serrano, Surpin, Raikhel, Rojo; (Journal Article)

Delayed upwelling alters nearshore coastal ocean ecosystems in the northern California current.

Barth, Menge, Lubchenco, Chan, Bane, Kirincich, McManus, Nielsen, Pierce, Washburn; (Journal Article)

Ischemic insults promote epigenetic reprogramming of {micro} opioid receptor expression in hippocampal neurons.

Formisano, Noh, Miyawaki, Mashiko, Bennett, Zukin; (Journal Article)

Accurate, conformation-dependent predictions of solvent effects on protein ionization constants.

Barth, Alber, Harbury; (JOURNAL ARTICLE)

Embryonic chimerism does not induce tolerance in an invertebrate model organism.

Poudyal, Rosa, Powell, Moreno, Dellaporta, Buss, Lakkis; (Journal Article)

Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles.

Baumgart, Hammond, Sengupta, Hess, Holowka, Baird, Webb; (Journal Article)

HIV-tat induces formation of an LRP-PSD-95- NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes.

Eugenin, King, Nath, Calderon, Zukin, Bennett, Berman; (Journal Article)

Unified picture of the oxygen isotope effect in cuprate superconductors.

Chen, Struzhkin, Wu, Lin, Hemley, Mao; (Journal Article)

Insight into the selectivity and gating functions of Streptomyces lividans KcsA.

Negoda, Xian, Reusch; (Journal Article)

Genetic deletion of p66Shc adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress.

Camici, Schiavoni, Francia, Bachschmid, Martin-Padura, Hersberger, Tanner, Pelicci, Volpe, Anversa, Lüscher, Cosentino; (JOURNAL ARTICLE)

Induction of the celC operon of Clostridium thermocellum by laminaribiose.

Newcomb, Chen, Wu; (Journal Article)

Apoptotic surge of potassium currents is mediated by p38 phosphorylation of Kv2.1.

Redman, He, Hartnett, Jefferson, Hu, Rosenberg, Levitan, Aizenman; (Journal Article)

c-Myb is required for progenitor cell homeostasis in colonic crypts.

Malaterre, Carpinelli, Ernst, Alexander, Cooke, Sutton, Dworkin, Heath, Frampton, McArthur, Clevers, Hilton, Mantamadiotis, Ramsay; (Journal Article)

Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma.

Peacock, Wang, Gesell, Corcoran-Schwartz, Jones, Kim, Devereux, Rhodes, Huff, Beachy, Watkins, Matsui; (Journal Article)

Small is big: The microfossil perspective on human-plant interaction.

Sandweiss; (Journal Article)

Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma.

Soroceanu, Kharbanda, Chen, Soriano, Aldape, Misra, Zha, Forrest, Nigro, Modrusan, Feuerstein, Phillips; (Journal Article)

Stage-dependent reactivity of thymocytes to self-peptide-MHC complexes.

Leng, Ge, Nguyen, Eisen, Chen; (JOURNAL ARTICLE)

E-Syts, a family of membranous Ca2+-sensor proteins with multiple C2 domains.

Min, Chang, Südhof; (Journal Article)

Using DNA to track the origin of the largest ivory seizure since the 1989 trade ban.

Wasser, Mailand, Booth, Mutayoba, Kisamo, Clark, Stephens; (Journal Article)

Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer.

Hamanishi, Mandai, Iwasaki, Okazaki, Tanaka, Yamaguchi, Higuchi, Yagi, Takakura, Minato, Honjo, Fujii; (Journal Article)

G{alpha}i2-mediated signaling events in the endothelium are involved in controlling leukocyte extravasation.

Pero, Borchers, Spicher, Ochkur, Sikora, Rao, Abdala-Valencia, O'neill, Shen, McGarry, Lee, Cook-Mills, Sriramarao, Simon, Birnbaumer, Lee; (Journal Article)

Relationship between the structure of SET/TAF-Ibeta/INHAT and its histone chaperone activity.

Muto, Senda, Akai, Sato, Suzuki, Nagai, Senda, Horikoshi; (Journal Article)

Strategy for reversing resistance to a single anticancer agent in human prostate and pancreatic carcinomas.

Lebedeva, Washington, Sarkar, Clark, Fine, Dent, Curiel, Turro, Fisher; (Journal Article)

Direct visualization of Escherichia coli chemotaxis receptor arrays using cryo-electron microscopy.

Zhang, Khursigara, Hartnell, Subramaniam; (Journal Article)

From the Cover: Pollen tetrad-based visual assay for meiotic recombination in Arabidopsis.

Francis, Lam, Harrison, Bey, Berchowitz, Copenhaver; (Journal Article)

Functional residues serve a dominant role in mediating the cooperativity of the protein ensemble.

Liu, Whitten, Hilser; (Journal Article)

On the thermodynamic stability of a charged arginine side chain in a transmembrane helix.

Dorairaj, Allen; (JOURNAL ARTICLE)

Retraction for Ma and Chang, Structure of the multidrug resistance efflux transporter EmrE from Escherichia coli.

Ma, Chang; (Journal Article)

Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells.

Liu, Asakura, Inoue, Nakamura, Sano, Niu, Chen, Schwartz, Schneider; (Journal Article)

Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice.

Rozeboom, Akil, Seasholtz; (Journal Article)

WD40 protein Mda1 is purified with Dnm1 and forms a dividing ring for mitochondria before Dnm1 in Cyanidioschyzon merolae.

Nishida, Yagisawa, Kuroiwa, Yoshida, Kuroiwa; (Journal Article)

FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression.

Li, Samanta, Song, Iacono, Bembas, Tao, Basu, Riley, Hancock, Shen, Saouaf, Greene; (Journal Article)

Confirmation of Neanderthal/modern human interstratification at the Chatelperronian type-site.

Mellars, Gravina, Bronk Ramsey; (Journal Article)

RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells.

Vasyutina, Lenhard, Wende, Erdmann, Epstein, Birchmeier; (Journal Article)

SseL, a Salmonella deubiquitinase required for macrophage killing and virulence.

Rytkönen, Poh, Garmendia, Boyle, Thompson, Liu, Freemont, Hinton, Holden; (Journal Article)

Modulating seed beta-ketoacyl-acyl carrier protein synthase II level converts the composition of a temperate seed oil to that of a palm-like tropical oil.

Pidkowich, Nguyen, Heilmann, Ischebeck, Shanklin; (Journal Article)

Homogenization of regional river dynamics by dams and global biodiversity implications.

Poff, Olden, Merritt, Pepin; (JOURNAL ARTICLE)

Developmental vision determines the reference frame for the multisensory control of action.

Röder, Kusmierek, Spence, Schicke; (Journal Article)

Antibody-catalyzed anaerobic destruction of methamphetamine.

Xu, Hixon, Yamamoto, McAllister, Wentworth, Wentworth, Janda; (Journal Article)

PSD-95 is required for activity-driven synapse stabilization.

Ehrlich, Klein, Rumpel, Malinow; (Journal Article)

Loss of androgen receptor binding to selective androgen response elements causes a reproductive phenotype in a knockin mouse model.

Schauwaers, De Gendt, Saunders, Atanassova, Haelens, Callewaert, Moehren, Swinnen, Verhoeven, Verrijdt, Claessens; (JOURNAL ARTICLE)

Bioinformatic prediction and experimental validation of a microRNA-directed tandem trans-acting siRNA cascade in Arabidopsis.

Chen, Li, Wu; (Journal Article)

Structure and function of a hexameric copper-containing nitrite reductase.

Nojiri, Xie, Inoue, Yamamoto, Matsumura, Kataoka, Deligeer, Yamaguchi, Kai, Suzuki; (Journal Article)

Two forms of single-vesicle astrocyte exocytosis imaged with total internal reflection fluorescence microscopy.

Bowser, Khakh; (Journal Article)

Gallium (III) triflate catalyzed efficient Strecker reaction of ketones and their fluorinated analogs.

Prakash, Mathew, Panja, Alconcel, Vaghoo, Do, Olah; (Journal Article)

A female-biased expressed elongase involved in long-chain hydrocarbon biosynthesis and courtship behavior in Drosophila melanogaster.

Chertemps, Duportets, Labeur, Ueda, Takahashi, Saigo, Wicker-Thomas; (Journal Article)

From the Cover: Endogenous IL-12 triggers an antiangiogenic program in melanoma cells.

Airoldi, Di Carlo, Cocco, Taverniti, D'Antuono, Ognio, Watanabe, Ribatti, Pistoia; (Journal Article)

Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46.

Walzer, Bléry, Chaix, Fuseri, Chasson, Robbins, Jaeger, André, Gauthier, Daniel, Chemin, Morel, Dalod, Imbert, Pierres, Moretta, Romagné, Vivier; (Journal Article)

A genomic screen for activators of the antioxidant response element.

Liu, Kern, Walker, Johnson, Schultz, Luesch; (JOURNAL ARTICLE)

The metabolic signature related to high plant growth rate in Arabidopsis thaliana.

Meyer, Steinfath, Lisec, Becher, Witucka-Wall, Törjék, Fiehn, Eckardt, Willmitzer, Selbig, Altmann; (Journal Article)

Inhibition of regulated proteolysis by RseB.

Cezairliyan, Sauer; (Journal Article)

Human polymorphism at microRNAs and microRNA target sites.

Saunders, Liang, Li; (Journal Article)

Spliced leader RNA trans-splicing in dinoflagellates.

Zhang, Hou, Miranda, Campbell, Sturm, Gaasterland, Lin; (Journal Article)

Noninfectious entry of HIV-1 into peripheral and brain macrophages mediated by the mannose receptor.

Trujillo, Rogers, Molina, Dangond, McLane, Essex, Brain; (JOURNAL ARTICLE)

Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T.

Zhang, Guo, Yu, Possemato, Chen, Zheng, Polakiewicz, Kinzler, Vogelstein, Velculescu, Wang; (Journal Article)

Active tissue-specific DNA demethylation conferred by somatic cell nuclei in stable heterokaryons.

Zhang, Pomerantz, Sen, Palermo, Blau; (Journal Article)

Ca2+ sparks operated by membrane depolarization require isoform 3 ryanodine receptor channels in skeletal muscle.

Pouvreau, Royer, Yi, Brum, Meissner, Ríos, Zhou; (JOURNAL ARTICLE)

Male fetal germ cells are targets for androgens that physiologically inhibit their proliferation.

Merlet, Racine, Moreau, Moreno, Habert; (JOURNAL ARTICLE)

Circadian variation of blood pressure and the vascular response to asynchronous stress.

Curtis, Cheng, Kapoor, Reilly, Price, Fitzgerald; (Journal Article)

Suppression of HIV-specific T cell activity by lymph node CD25+ regulatory T cells from HIV-infected individuals.

Kinter, McNally, Riggin, Jackson, Roby, Fauci; (Journal Article)

Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2.

Young, Hassan, Yang, Galindo, Javed, Zaidi, Furcinitti, Lapointe, Montecino, Lian, Stein, van Wijnen, Stein; (Journal Article)

Regulation of the stringent response is the essential function of the conserved bacterial G protein CgtA in Vibrio cholerae.

Raskin, Judson, Mekalanos; (Journal Article)

An estimate of anthropogenic CO2 inventory from decadal changes in oceanic carbon content.

Tanhua, Körtzinger, Friis, Waugh, Wallace; (Journal Article)

Biofortification of plant-based food: Enhancing folate levels by metabolic engineering.

Dellapenna; (Journal Article)

Neuronal growth and survival mediated by eIF5A, a polyamine-modified translation initiation factor.

Huang, Higginson, Hester, Park, Snyder; (Journal Article)

Synthesis and evaluation of transthyretin amyloidosis inhibitors containing carborane pharmacophores.

Julius, Farha, Chiang, Perry, Hawthorne; (JOURNAL ARTICLE)

Inhibitory factors associated with anaphase-promoting complex/cylosome in mitotic checkpoint.

Braunstein, Miniowitz, Moshe, Hershko; (JOURNAL ARTICLE)

Coxsackie B4 virus infection of {beta} cells and natural killer cell insulitis in recent-onset type 1 diabetic patients.

Dotta, Censini, van Halteren, Marselli, Masini, Dionisi, Mosca, Boggi, Muda, Del Prato, Elliott, Covacci, Rappuoli, Roep, Marchetti; (JOURNAL ARTICLE)

Retaliatory mafia behavior by a parasitic cowbird favors host acceptance of parasitic eggs.

Hoover, Robinson; (Journal Article)

Dysfunction of GABAA receptor glycolysis-dependent modulation in human partial epilepsy.

Laschet, Kurcewicz, Minier, Trottier, Khallou-Laschet, Louvel, Gigout, Turak, Biraben, Scarabin, Devaux, Chauvel, Pumain; (Journal Article)

Impaired angiogenesis in aminopeptidase N-null mice.

Rangel, Sun, Guzman-Rojas, Ozawa, Sun, Giordano, Van Pelt, Tinkey, Behringer, Sidman, Arap, Pasqualini; (Journal Article)

Host shutoff during productive Epstein-Barr virus infection is mediated by BGLF5 and may contribute to immune evasion.

Rowe, Glaunsinger, van Leeuwen, Zuo, Sweetman, Ganem, Middeldorp, Wiertz, Ressing; (Journal Article)

A polyphosphate kinase 1 (ppk1) mutant of Pseudomonas aeruginosa exhibits multiple ultrastructural and functional defects.

Fraley, Rashid, Lee, Gottschalk, Harrison, Wood, Brown, Kornberg; (Journal Article)

First-spike latency information in single neurons increases when referenced to population onset.

Chase, Young; (JOURNAL ARTICLE)

Hypoxia-inducible factor 1{alpha} stabilization by carbon monoxide results in cytoprotective preconditioning.

Chin, Jiang, Wegiel, Wang, Macdonald, Zhang, Gallo, Cszimadia, Bach, Lee, Otterbein; (JOURNAL ARTICLE)

Phylogenetic signal in plant pathogen-host range.

Gilbert, Webb; (JOURNAL ARTICLE)

Lymphotoxin {beta} receptor signaling is required for inflammatory lymphangiogenesis in the thyroid.

Furtado, Marinkovic, Martin, Garin, Hoch, Hubner, Chen, Genden, Skobe, Lira; (JOURNAL ARTICLE)

From the Cover: Fish extinctions alter nutrient recycling in tropical freshwaters.

McIntyre, Jones, Flecker, Vanni; (Journal Article)

Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1{gamma}.

Kuroda, Moss, Vaughan; (Journal Article)

Domain-swapped dimerization of the HIV-1 capsid C-terminal domain.

Ivanov, Tsodikov, Kasanov, Ellenberger, Wagner, Collins; (Journal Article)

Dose-dependent cross-talk between the transforming growth factor-beta and interleukin-1 signaling pathways.

Lu, Tian, Han, Vogelbaum, Stark; (Journal Article)

Experimental constraints on mate preferences in Drosophila pseudoobscura decrease offspring viability and fitness of mated pairs.

Anderson, Kim, Gowaty; (Journal Article)

Electronic energy delocalization and dissipation in single- and double-stranded DNA.

Buchvarov, Wang, Raytchev, Trifonov, Fiebig; (JOURNAL ARTICLE)

Brain protection using autologous bone marrow cell, metalloproteinase inhibitors, and metabolic treatment in cerebral ischemia.

Baker, Sica, Work, Williams-Ignarro, de Nigris, Lerman, Casamassimi, Lanza, Schiano, Rienzo, Ignarro, Napoli; (Journal Article)

Modulation of Drosophila male behavioral choice.

Certel, Savella, Schlegel, Kravitz; (Journal Article)

Key feature of the catalytic cycle of TNF-{alpha} converting enzyme involves communication between distal protein sites and the enzyme catalytic core.

Solomon, Akabayov, Frenkel, Milla, Sagi; (JOURNAL ARTICLE)

Concerted ATP-induced allosteric transitions in GroEL facilitate release of protein substrate domains in an all-or-none manner.

Kipnis, Papo, Haran, Horovitz; (Journal Article)

Loss of a histone deacetylase dramatically alters the genomic distribution of Spo11p-catalyzed DNA breaks in Saccharomyces cerevisiae.

Mieczkowski, Dominska, Buck, Lieb, Petes; (Journal Article)

Innateness and culture in the evolution of language.

Kirby, Dowman, Griffiths; (JOURNAL ARTICLE)

Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1.

Peer, Zhu, Carman, Lieberman, Shimaoka; (Journal Article)

Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages.

Timmons, Wennmalm, Larsson, Walden, Lassmann, Petrovic, Hamilton, Gimeno, Wahlestedt, Baar, Nedergaard, Cannon; (Journal Article)

Peripheral multidendritic sensory neurons are necessary for rhythmic locomotion behavior in Drosophila larvae.

Song, Onishi, Jan, Jan; (JOURNAL ARTICLE)

Distinctive features of large complex virus genomes and proteomes.

Mrázek, Karlin; (JOURNAL ARTICLE)

Interaction between transcellular and paracellular water transport pathways through Aquaporin 5 and the tight junction complex.

Kawedia, Nieman, Boivin, Melvin, Kikuchi, Hand, Lorenz, Menon; (Journal Article)

Orai proteins interact with TRPC channels and confer responsiveness to store depletion.

Liao, Erxleben, Yildirim, Abramowitz, Armstrong, Birnbaumer; (Journal Article)

On the mechanism of wing size determination in fly development.

Hufnagel, Teleman, Rouault, Cohen, Shraiman; (Journal Article)

Identification of Abcc6 as the major causal gene for dystrophic cardiac calcification in mice through integrative genomics.

Meng, Vera, Che, Wang, Wang, Ingram-Drake, Schadt, Drake, Lusis; (Journal Article)

Methionine transmethylation and transsulfuration in the piglet gastrointestinal tract.

Riedijk, Stoll, Chacko, Schierbeek, Sunehag, van Goudoever, Burrin; (Journal Article)

Innate response to self-antigen significantly exacerbates burn wound depth.

Suber, Carroll, Moore; (Journal Article)

From the Cover: Antipsychotic drug-induced weight gain mediated by histamine H1 receptor-linked activation of hypothalamic AMP-kinase.

Kim, Huang, Snowman, Teuscher, Snyder; (Journal Article)

Drug target interaction energies by the kernel energy method in aminoglycoside drugs and ribosomal A site RNA targets.

Huang, Massa, Karle; (Journal Article)

Network activity-independent coordinated gene expression program for synapse assembly.

Valor, Charlesworth, Humphreys, Anderson, Grant; (Journal Article)

The role of evolution in the invasion process.

Novak; (Journal Article)

Loss of {alpha}-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function.

Ikegami, Heier, Taruishi, Takagi, Mukai, Shimma, Taira, Hatanaka, Morone, Yao, Campbell, Yuasa, Janke, Macgregor, Setou; (Journal Article)

Mechanisms controlling the acquisition of a cardiac phenotype by liver stem cells.

Muller-Borer, Cascio, Esch, Kim, Coleman, Grisham, Anderson, Malouf; (Journal Article)

Unlocking and opening a DNA gate.

Wang; (JOURNAL ARTICLE)

Profile of Monica G. Turner.

Zagorski; (JOURNAL ARTICLE)

From the Cover: Starch grain evidence for the preceramic dispersals of maize and root crops into tropical dry and humid forests of Panama.

Dickau, Ranere, Cooke; (Journal Article)

Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis.

Dominguez, Hughes, Pan, Simmons, Daly, Anderson, Noguera-Troise, Murphy, Valenzuela, Davis, Thurston, Yancopoulos, Gale; (Journal Article)

Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts.

Meinecke, Cinski, Baier, Peters, Dankbar, Wille, Drynda, Mendoza, Gay, Hay, Ink, Gay, Pap; (JOURNAL ARTICLE)

The role of cells refractory to productive infection in acute hepatitis B viral dynamics.

Ciupe, Ribeiro, Nelson, Dusheiko, Perelson; (JOURNAL ARTICLE)

MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors.

Kato, Zhang, Wang, Lanting, Yuan, Rossi, Natarajan; (Journal Article)

Nonlinear scaling of space use in human hunter-gatherers.

Hamilton, Milne, Walker, Brown; (Journal Article)

RNA aptamers directed to discrete functional sites on a single protein structural domain.

Shi, Fan, Sevilimedu, Lis; (Journal Article)

A porphomethene inhibitor of uroporphyrinogen decarboxylase causes porphyria cutanea tarda.

Phillips, Bergonia, Reilly, Franklin, Kushner; (JOURNAL ARTICLE)

Transgenic cyclin E triggers dysplasia and multiple pulmonary adenocarcinomas.

Ma, Fiering, Black, Liu, Yuan, Memoli, Robbins, Bentley, Tsongalis, Demidenko, Freemantle, Dmitrovsky; (JOURNAL ARTICLE)

Ablation of D1 dopamine receptor-expressing cells generates mice with seizures, dystonia, hyperactivity, and impaired oral behavior.

Gantois, Fang, Jiang, Babovic, Lawrence, Ferreri, Teper, Jupp, Ziebell, Morganti-Kossmann, O'brien, Nally, Schütz, Waddington, Egan, Drago; (Journal Article)

Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family.

Banga, Gao, Shen, Fiscus, Zong, Chen, Luo; (JOURNAL ARTICLE)

Intranasal immunization with heterologously expressed polysaccharide protects against multiple Pseudomonas aeruginosa infections.

Digiandomenico, Rao, Harcher, Zaidi, Gardner, Neely, Pier, Goldberg; (Journal Article)

Growth of novel protein structural data.

Levitt; (Journal Article)

Electrostatic gating of a nanometer water channel.

Li, Gong, Lu, Li, Fang, Zhou; (Journal Article)

From the Cover: Interfacial plasticity governs strain rate sensitivity and ductility in nanostructured metals.

Zhu, Li, Samanta, Kim, Suresh; (Journal Article)

From the Cover: Myosin Va maneuvers through actin intersections and diffuses along microtubules.

Ali, Krementsova, Kennedy, Mahaffy, Pollard, Trybus, Warshaw; (Journal Article)

A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer.

Amos-Landgraf, Kwong, Kendziorski, Reichelderfer, Torrealba, Weichert, Haag, Chen, Waller, Gould, Dove; (JOURNAL ARTICLE)

Genomic identification and in vitro reconstitution of a complete biosynthetic pathway for the osmolyte di-myo-inositol-phosphate.

Rodionov, Kurnasov, Stec, Wang, Roberts, Osterman; (Journal Article)

S-adenosylmethionine directly inhibits binding of 30S ribosomal subunits to the SMK box translational riboswitch RNA.

Fuchs, Grundy, Henkin; (JOURNAL ARTICLE)

Predicting coupling limits from an experimentally determined energy landscape.

Street, Bradley, Barrick; (JOURNAL ARTICLE)

Illuminating the molecular basis for some antipsychotic drug-induced metabolic burden.

Meltzer; (Journal Article)

From the Cover: Modeling sporadic loss of heterozygosity in mice by using mosaic analysis with double markers (MADM).

Muzumdar, Luo, Zong; (Journal Article)

Developmental hearing loss eliminates long-term potentiation in the auditory cortex.

Kotak, Breithaupt, Sanes; (Journal Article)

Chlorination of lignin by ubiquitous fungi has a likely role in global organochlorine production.

Ortiz-Bermúdez, Hirth, Srebotnik, Hammel; (Journal Article)

Genomic analysis of the Mozambique strain of Vibrio cholerae O1 reveals the origin of El Tor strains carrying classical CTX prophage.

Faruque, Tam, Chowdhury, Diraphat, Dziejman, Heidelberg, Clemens, Mekalanos, Nair; (JOURNAL ARTICLE)

Single M13 bacteriophage tethering and stretching.

Khalil, Ferrer, Brau, Kottmann, Noren, Lang, Belcher; (JOURNAL ARTICLE)

A population genetics model with recombination hotspots that are heterogeneous across the population.

Calabrese; (Journal Article)

Competition for antigen determines the stability of T cell-dendritic cell interactions during clonal expansion.

Garcia, Pradelli, Celli, Beuneu, Simon, Bousso; (Journal Article)

Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression.

Yanai, Chen, Inuzuka, Kondo, Mak, Takaoka, Honda, Taniguchi; (Journal Article)

Intramolecular domain-domain association/dissociation and phosphoryl transfer in the mannitol transporter of Escherichia coli are not coupled.

Suh, Iwahara, Clore; (Journal Article)

Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation.

Miller, McDearmon, Panda, Hayes, Zhang, Andrews, Antoch, Walker, Esser, Hogenesch, Takahashi; (Journal Article)

Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells.

Zha, Alt, Cheng, Brush, Li; (Journal Article)

Serial analysis of chromatin occupancy identifies beta-catenin target genes in colorectal carcinoma cells.

Yochum, McWeeney, Rajaraman, Cleland, Peters, Goodman; (Journal Article)

RNA-binding proteins that inhibit RNA virus infection.

Zhu, Gopinath, Murali, Yi, Hayward, Zhu, Kao; (Journal Article)

Crystal structures reveal a thiol protease-like catalytic triad in the C-terminal region of Pasteurella multocida toxin.

Kitadokoro, Kamitani, Miyazawa, Hanajima-Ozawa, Fukui, Miyake, Horiguchi; (JOURNAL ARTICLE)

beta cell transdifferentiation does not contribute to preneoplastic/metaplastic ductal lesions of the pancreas by genetic lineage tracing in vivo.

Strobel, Dor, Stirman, Trainor, Fernández-Del Castillo, Warshaw, Thayer; (Journal Article)

Monitoring the function of membrane transport proteins in detergent-solubilized form.

Quick, Javitch; (Journal Article)

Adrenomedullin gene expression differences in mice do not affect blood pressure but modulate hypertension-induced pathology in males.

Caron, Hagaman, Nishikimi, Kim, Smithies; (Journal Article)

Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy.

Radke, Peng, Wu, McNabb, Nelson, Granzier, Gotthardt; (Journal Article)

Sensitivity of T cells to antigen and antagonism emerges from differential regulation of the same molecular signaling module.

Wylie, Das, Chakraborty; (JOURNAL ARTICLE)

Differential localization of coatomer complex isoforms within the Golgi apparatus.

Moelleken, Malsam, Betts, Movafeghi, Reckmann, Meissner, Hellwig, Russell, Söllner, Brügger, Wieland; (Journal Article)

PGC-1{beta} controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis.

Sonoda, Mehl, Chong, Nofsinger, Evans; (JOURNAL ARTICLE)

Folding free-energy landscape of villin headpiece subdomain from molecular dynamics simulations.

Lei, Wu, Liu, Duan; (JOURNAL ARTICLE)

Model-based assessment of the role of human-induced climate change in the 2005 Caribbean coral bleaching event.

Donner, Knutson, Oppenheimer; (JOURNAL ARTICLE)

Microparticle-based delivery of oxytocin receptor antisense DNA in the medial amygdala blocks social recognition in female mice.

Choleris, Little, Mong, Puram, Langer, Pfaff; (Journal Article)

Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine.

Taylor, Lynch, Sanchez, Olausson, Nestler, Bibb; (Journal Article)

Steroid receptor coactivator 3 is a coactivator for myocardin, the regulator of smooth muscle transcription and differentiation.

Li, Haque, Lu, Li, Karas, Mendelsohn; (Journal Article)

Evidence of spatially bound gene regulation in Mus musculus: Decreased gene expression proximal to microRNA genomic location.

Inaoka, Fukuoka, Kohane; (JOURNAL ARTICLE)

Single-molecule measurements of the opening and closing of the DNA gate by eukaryotic topoisomerase II.

Smiley, Collins, Hammes, Hsieh; (JOURNAL ARTICLE)

Regulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1.

Berger, Lau, Ziegler; (Journal Article)

A haplotype of the human CXCR1 gene protective against rapid disease progression in HIV-1+ patients.

Vasilescu, Terashima, Enomoto, Heath, Poonpiriya, Gatanaga, Do, Diop, Hirtzig, Auewarakul, Lauhakirti, Sura, Charneau, Marullo, Therwath, Oka, Kanegasaki, Lathrop, Matsushima, Zagury, Matsuda; (Journal Article)

Quantifying DNA-protein binding specificities by using oligonucleotide mass tags and mass spectroscopy.

Zhang, Kasif, Cantor; (Journal Article)

Assisted reproductive technologies do not alter mutation frequency or spectrum.

Caperton, Murphey, Yamazaki, McMahan, Walter, Yanagimachi, McCarrey; (JOURNAL ARTICLE)

Trophoblast cell activation by trophinin ligation is implicated in human embryo implantation.

Sugihara, Sugiyama, Byrne, Wolf, Lowitz, Kobayashi, Kabir-Salmani, Nadano, Aoki, Nozawa, Nakayama, Mustelin, Ruoslahti, Yamaguchi, Fukuda; (Journal Article)

The Nf2 tumor suppressor regulates cell-cell adhesion during tissue fusion.

McLaughlin, Kruger, Slocum, Crowley, Michaud, Huang, Magendantz, Jacks; (Journal Article)

From the Cover: Induced mitotic recombination of p53 in vivo.

Wang, Warren, Bradley; (Journal Article)

Small RNA-mediated chromatin silencing directed to the 3' region of the Arabidopsis gene encoding the developmental regulator, FLC.

Swiezewski, Crevillen, Liu, Ecker, Jerzmanowski, Dean; (Journal Article)

The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage.

Wang, Yu, Zhang; (Journal Article)

Potential targets of FOXL2, a transcription factor involved in craniofacial and follicular development, identified by transcriptomics.

Batista, Vaiman, Dausset, Fellous, Veitia; (JOURNAL ARTICLE)

Role of RNA polymerase IV in plant small RNA metabolism.

Zhang, Henderson, Lu, Green, Jacobsen; (Journal Article)