Nature

Collective minds.

Couzin; (Journal Article)

A genome-wide association study identifies novel risk loci for type 2 diabetes.

Sladek, Rocheleau, Rung, Dina, Shen, Serre, Boutin, Vincent, Belisle, Hadjadj, Balkau, Heude, Charpentier, Hudson, Montpetit, Pshezhetsky, Prentki, Posner, Balding, Meyre, Polychronakos, Froguel; (JOURNAL ARTICLE)

US air pollution is harmful and fine particles can kill.

Moorhouse; (Journal Article)

India's watchdog: A breath of fresh air.

Mandavilli; (Journal Article)

Structural Biology: Analysis of 'downhill' protein folding.

Ferguson, Sharpe, Johnson, Schartau, Fersht; (Journal Article)

Structure and function of the histone chaperone CIA/ASF1 complexed with histones H3 and H4.

Natsume, Eitoku, Akai, Sano, Horikoshi, Senda; (JOURNAL ARTICLE)

Research highlights.

none; (Journal Article)

A cytosolic trans-activation domain essential for ammonium uptake.

Loqué, Lalonde, Looger, von Wirén, Frommer; (JOURNAL ARTICLE)

Charge- and size-based separation of macromolecules using ultrathin silicon membranes.

Striemer, Gaborski, McGrath, Fauchet; (Journal Article)

The Earth's 'hum' is driven by ocean waves over the continental shelves.

Webb; (Journal Article)

Early gas stripping as the origin of the darkest galaxies in the Universe.

Mayer, Kazantzidis, Mastropietro, Wadsley; (Journal Article)

Norway unveils design of 'doomsday' seed bank.

Hopkin; (Journal Article)

France strives for sharper image.

none; (Journal Article)

Physicists pitch biggest accelerator.

Brumfiel; (Journal Article)

Science in culture.

Kemp; (Journal Article)

Analytical chemistry: Sense and versatility.

de Silva; (Journal Article)

Vascular Biology: Vessel guidance.

Gridley; (Journal Article)

Time for a change.

Alvarez; (Journal Article)

Making the paper: John Tooby.

none; (Journal Article)

Disputed inquiry clears bubble-fusion engineer.

Reich; (Journal Article)

Pigments help to date disputed masterpiece.

Abbott; (Journal Article)

Plasma physics: On the crest of a wake.

Bingham; (Journal Article)

Seeking a PhD abroad.

Banks; (Journal Article)

Opposites attract.

Whitfield; (Journal Article)

50 & 100 years ago.

none; (Journal Article)

Structural Biology: Analysis of protein-folding cooperativity.

Zhou, Bai; (Journal Article)

Key biology databases go wiki.

Giles; (Journal Article)

Ignore the spurious claims of private fossil-hoarders.

Hartenberger; (Journal Article)

Developmental biology: Cell fate in the mammary gland.

Tong, Hotamisligil; (Journal Article)

Correction.

none; (Journal Article)

Structural definition of a conserved neutralization epitope on HIV-1 gp120.

Zhou, Xu, Dey, Hessell, Van Ryk, Xiang, Yang, Zhang, Zwick, Arthos, Burton, Dimitrov, Sodroski, Wyatt, Nabel, Kwong; (Journal Article)

Methods in full.

none; (Journal Article)

Food chains: Killer in the kelp.

Schrope; (Journal Article)

Chemical rescue of cleft palate and midline defects in conditional GSK-3beta mice.

Liu, Arron, Stankunas, Crabtree, Longaker; (JOURNAL ARTICLE)

Broad sweep of genome zeroes in on diabetes.

Russo; (Journal Article)

Nanofluidics: silicon for the perfect membrane.

van den Berg, Wessling; (Comment, News)

Quantum mechanics: The truth about reality.

Weihs; (Journal Article)

Conservation biology: The diversity of biodiversity.

Mooers; (Journal Article)

Shooting for the moon.

Roland; (Journal Article)

Taxi-cab teaching.

Ledford; (Journal Article)

Structural Biology: Analysis of 'downhill' protein folding; Analysis of protein-folding cooperativity (Reply).

Sadqi, Fushman, Muñoz; (Journal Article)

The architecture of human kin detection.

Lieberman, Tooby, Cosmides; (Journal Article)

Fossils: professionals and amateurs can cooperate.

Hughes; (Journal Article)

Berkeley's energy deal with BP sparks unease.

Dalton; (Journal Article)

Preserving the evolutionary potential of floras in biodiversity hotspots.

Forest, Grenyer, Rouget, Davies, Cowling, Faith, Balmford, Manning, ProcheÅŸ, van der Bank, Reeves, Hedderson, Savolainen; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

News in brief.

none; (Journal Article)

Energy doubling of 42 GeV electrons in a metre-scale plasma wakefield accelerator.

Blumenfeld, Clayton, Decker, Hogan, Huang, Ischebeck, Iverson, Joshi, Katsouleas, Kirby, Lu, Marsh, Mori, Muggli, Oz, Siemann, Walz, Zhou; (Journal Article)

Ultralow-power organic complementary circuits.

Klauk, Zschieschang, Pflaum, Halik; (Journal Article)

Abstractions.

none; (Journal Article)

Quality evaluation needs some better quality tools.

Döring; (Journal Article)

Key collaboration.

none; (Journal Article)

Scientists in love: When two worlds collide.

Ouellette; (Journal Article)

Human Genetics: Variants in common diseases.

Freimer, Sabatti; (JOURNAL ARTICLE)

Lost in translation.

La Madeleine; (Journal Article)

Sidelines.

none; (Journal Article)

A word in the right place.

Goldston; (Journal Article)

Indian voices.

none; (Journal Article)

Food for thought.

none; (Journal Article)

Drosophila TCTP is essential for growth and proliferation through regulation of dRheb GTPase.

Hsu, Chern, Cai, Liu, Choi; (Journal Article)

Choose your own reward.

Clark; (Journal Article)


Science

U.S. academia. Radcliffe historian named Harvard president.

Lawler; (News)

Who is et al.?

McDonald; (Letter)

Thermoelectricity in Molecular Junctions.

Reddy, Jang, Segalman, Majumdar; (JOURNAL ARTICLE)

Magmatic and crustal differentiation history of granitic rocks from Hf-O isotopes in zircon.

Kemp, Hawkesworth, Foster, Paterson, Woodhead, Hergt, Gray, Whitehouse; (Journal Article, Research Support, Non-U.S. Gov't)

Cell biology. A lonely crusade.

Chatterjee; (News)

U.S. research funding. Science adviser says that pruning is the key to a healthy budget.

Mervis; (News)

Data sharing. New Swiss influenza database to test promises of access.

Enserink; (News)

Physics. Two for the price of one.

Schofield; (Comment, Journal Article)

Polymerizing actin fibers position integrins primed to probe for adhesion sites.

Galbraith, Yamada, Galbraith; (Journal Article, Research Support, N.I.H., Extramural)

Public health. 911.gov.

Shneiderman, Preece; (Journal Article)

Geology. On the origins of granites.

Eiler; (Comment, Journal Article)

U.S. nanotechnology. Health and safety research slated for sizable gains.

Service; (News)

Experimental realization of Wheeler's delayed-choice gedanken experiment.

Jacques, Wu, Grosshans, Treussart, Grangier, Aspect, Roch; (Journal Article, Research Support, Non-U.S. Gov't)

Reversible concerted ligand substitution at alternating metal sites in an extended solid.

Bradshaw, Warren, Rosseinsky; (Journal Article, Research Support, Non-U.S. Gov't)

A voice over the smoke for academic freedom.

Jue; (Comment, Letter)

Multipotent Drosophila intestinal stem cells specify daughter cell fates by differential notch signaling.

Ohlstein, Spradling; (Journal Article)

Faith and science. In Europe's mailbag: a glossy attack on evolution.

Enserink; (News)

Predation risk affects reproductive physiology and demography of elk.

Creel, Christianson, Liley, Winnie; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

An Active Subglacial Water System in West Antarctica Mapped from Space.

Fricker, Scambos, Bindschadler, Padman; (JOURNAL ARTICLE)

Archaeal type III RuBisCOs function in a pathway for AMP metabolism.

Sato, Atomi, Imanaka; (Journal Article, Research Support, Non-U.S. Gov't)

Cell biology. Cases of mistaken identity.

Chatterjee; (News)

Maplike representation of celestial E-vector orientations in the brain of an insect.

Heinze, Homberg; (Journal Article, Research Support, Non-U.S. Gov't)

Sustainable well-being.

Pachauri; (Editorial)

Physics. A half-century late, alternative accelerator takes off.

Cartlidge; (News)

Biomedicine. Every joint has a silver lining.

Firestein; (Comment, Journal Article)

Research integrity. Bubble fusion researcher cleared of misconduct charges, but doubts linger.

Service; (News)

Limits to the Human Cancer Genome Project?

Loeb, Bielas; (Comment, Letter)

Computer science. Where are the exemplars?

Mézard; (Comment, Journal Article)

Anthropology. Some like it hot.

Knapp; (Comment, Journal Article)

The Calyptogena magnifica chemoautotrophic symbiont genome.

Newton, Woyke, Auchtung, Dilly, Dutton, Fisher, Fontanez, Lau, Stewart, Richardson, Barry, Saunders, Detter, Wu, Eisen, Cavanaugh; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Neuroscience. Where am I?

Fenton; (Comment, Journal Article)

Cell biology. When 60 lines don't add up.

Chatterjee; (News)

Multiple energy scales at a quantum critical point.

Gegenwart, Westerkamp, Krellner, Tokiwa, Paschen, Geibel, Steglich, Abrahams, Si; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

A clarification on global access to drugs.

Rys; (Comment, Letter)

Fracture-controlled paleo-fluid flow in Candor Chasma, Mars.

Okubo, McEwen; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Human Neuroblasts Migrate to the Olfactory Bulb via a Lateral Ventricular Extension.

Curtis, Kam, Nannmark, Anderson, Axell, Wikkelso, Holtås, van Roon-Mom, Björk-Eriksson, Nordborg, Frisen, Dragunow, Faull, Eriksson; (JOURNAL ARTICLE)

Archaeology. Saving a lost culture's megalithic jars.

Stone; (News)

Limits to the Human Cancer Genome Project?

Strauss; (Comment, Letter)

U.S. academia. MIT hunger strike: sour grapes, or the bitter taste of racism?

Bhattacharjee; (News)

The phosphothreonine lyase activity of a bacterial type III effector family.

Li, Xu, Zhou, Zhang, Long, Li, Chen, Zhou, Shao; (Journal Article, Research Support, Non-U.S. Gov't)

Applications of modern ferroelectrics.

Scott; (Journal Article)

Pattern separation in the dentate gyrus and CA3 of the hippocampus.

Leutgeb, Leutgeb, Moser, Moser; (Journal Article, Research Support, Non-U.S. Gov't)

Room-Temperature Quantum Hall Effect in Graphene.

Novoselov, Jiang, Zhang, Morozov, Stormer, Zeitler, Maan, Boebinger, Kim, Geim; (JOURNAL ARTICLE)

Starch fossils and the domestication and dispersal of chili peppers (Capsicum spp. L.) in the Americas.

Perry, Dickau, Zarrillo, Holst, Pearsall, Piperno, Berman, Cooke, Rademaker, Ranere, Raymond, Sandweiss, Scaramelli, Tarble, Zeidler; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Debating evidence for the origin of life on Earth.

Bada, Fegley, Miller, Lazcano, Cleaves, Hazen, Chalmers; (Comment, Letter)

Diagnostics. Amid debate, gene-based cancer test approved.

Couzin; (News)


Nature Methods

Harnessing homologous recombination in vitro to generate recombinant DNA via SLIC.

Li, Elledge; (JOURNAL ARTICLE)

Reproducible isolation of distinct, overlapping segments of the phosphoproteome.

Bodenmiller, Mueller, Mueller, Domon, Aebersold; (JOURNAL ARTICLE)


Nature Biotechnology

How the EU can fund your company.

Gilbert; (Journal Article)


Nature Medicine

Ca(2+) channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1.

Ludwiczek, Theurl, Muckenthaler, Jakab, Mair, Theurl, Kiss, Paulmichl, Hentze, Ritter, Weiss; (JOURNAL ARTICLE)

Europe's sweeping chemical law puts medicines in peril.

Keim; (News)


Nature Genetics

X chromosome repression by localization of the C. elegans dosage compensation machinery to sites of transcription initiation.

Ercan, Giresi, Whittle, Zhang, Green, Lieb; (JOURNAL ARTICLE)

A common coding variant in CASP8 is associated with breast cancer risk.

Cox, Dunning, Garcia-Closas, Balasubramanian, Reed, Pooley, Scollen, Baynes, Ponder, Chanock, Lissowska, Brinton, Peplonska, Southey, Hopper, McCredie, Giles, Fletcher, Johnson, Dos Santos Silva, Gibson, Bojesen, Nordestgaard, Axelsson, Torres, Hamann, Justenhoven, Brauch, Chang-Claude, Kropp, Risch, Wang-Gohrke, Schürmann, Bogdanova, Dörk, Fagerholm, Aaltonen, Blomqvist, Nevanlinna, Seal, Renwick, Stratton, Rahman, Sangrajrang, Hughes, Odefrey, Brennan, Spurdle, Chenevix-Trench, Beesley, Mannermaa, Hartikainen, Kataja, Kosma, Couch, Olson, Goode, Broeks, Schmidt, Hogervorst, Veer, Kang, Yoo, Noh, Ahn, Wedrén, Hall, Low, Liu, Milne, Ribas, Gonzalez-Neira, Benitez, Sigurdson, Stredrick, Alexander, Struewing, Pharoah, Easton; (JOURNAL ARTICLE)

The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells.

Cao, Shitara, Horii, Nagao, Imai, Abe, Hara, Hayashi, Yonekawa; (JOURNAL ARTICLE)

High-throughput oncogene mutation profiling in human cancer.

Thomas, Baker, Debiasi, Winckler, Laframboise, Lin, Wang, Feng, Zander, Macconnaill, Lee, Nicoletti, Hatton, Goyette, Girard, Majmudar, Ziaugra, Wong, Gabriel, Beroukhim, Peyton, Barretina, Dutt, Emery, Greulich, Shah, Sasaki, Gazdar, Minna, Armstrong, Mellinghoff, Hodi, Dranoff, Mischel, Cloughesy, Nelson, Liau, Mertz, Rubin, Moch, Loda, Catalona, Fletcher, Signoretti, Kaye, Anderson, Demetri, Dummer, Wagner, Herlyn, Sellers, Meyerson, Garraway; (JOURNAL ARTICLE)


Molecular Medicine


Proteomics

Identification of aluminum-responsive proteins in rice roots by a proteomic approach: Cysteine synthase as a key player in Al response.

Yang, Wang, Zhang, Shi, Qian, Peng; (JOURNAL ARTICLE)

Automated reporting from gel-based proteomics experiments using the open source Proteios database application.

Levander, Krogh, Wårell, Gärdén, James, Häkkinen; (JOURNAL ARTICLE)

SELDI-TOF-MS analysis of chloroquine resistant and sensitive Plasmodium falciparum strains.

Koncarevic, Bogumil, Becker; (JOURNAL ARTICLE)

Quantitative proteomic analysis of rat liver for carcinogenicity prediction in a 28-day repeated dose study.

Yamanaka, Yakabe, Saito, Sekijima, Shirai; (JOURNAL ARTICLE)

Developmental vitamin D deficiency alters brain protein expression in the adult rat: Implications for neuropsychiatric disorders.

Almeras, Eyles, Benech, Laffite, Villard, Patatian, Boucraut, Mackay-Sim, McGrath, Féron; (JOURNAL ARTICLE)

The proteome and transcriptome analysis of Bacillus subtilis in response to salicylic acid.

Van Duy, Mäder, Tran, Cavin, Tam, Albrecht, Hecker, Antelmann; (JOURNAL ARTICLE)

Proteomic approach for identification and characterization of novel immunostimulatory proteins from soluble antigens of Leishmania donovani promastigotes.

Gupta, Sisodia, Sinha, Hajela, Naik, Shasany, Dube; (JOURNAL ARTICLE)

Proteomic analysis of spinal protein expression in rats exposed to repeated intrathecal morphine injection.

Shui, Ho, Wang, Wu, Lin, Tao, Liaw; (JOURNAL ARTICLE)

Development and validation of a spectral library searching method for peptide identification from MS/MS.

Lam, Deutsch, Eddes, Eng, King, Stein, Aebersold; (JOURNAL ARTICLE)

A proteomic investigation of glomerular podocytes from a Denys-Drash Syndrome patient with a mutation in the Wilms tumour suppressor gene WT1.

Viney, Morrison, van den Heuvel, Ni, Mathieson, Saleem, Ladomery; (JOURNAL ARTICLE)


Nature Drug Discovery


BMC Bioinformatics

PASSIM - an open source software system for managing information in biomedical studies.

Viksna, Celms, Opmanis, Podnieks, Rucevskis, Zarins, Barrett, Guha Neogi, Krestyaninova, McCarthy, Brazma, Sarkans; (JOURNAL ARTICLE)

In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells.

Naamane, van Helden, Eizirik; (JOURNAL ARTICLE)

BioInfer: A corpus for information extraction in the biomedical domain.

Pyysalo, Ginter, Heimonen, Bjorne, Boberg, Jarvinen, Salakoski; (JOURNAL ARTICLE)

PLAN: A web platform for automating high-throughput BLAST searches and for managing and mining results.

He, Dai, Zhao; (JOURNAL ARTICLE)

msmsEval: Tandem mass spectral quality assignment for high-throughput proteomics.

Wong, Sullivan, Cartwright, Cagney; (JOURNAL ARTICLE)

BIRCH: A user-oriented, locally-customizable, bioinformatics system.

Fristensky; (JOURNAL ARTICLE)


Bioinformatics

Accurate automated clustering of two-dimensional data for single-nucleotide polymorphism genotyping by a combination of clustering methods: evaluation by large-scale real data.

Takitoh, Fujii, Mase, Takasaki, Yamazaki, Ohnishi, Yanagisawa, Nakamura, Kamatani; (Journal Article)

Analyzing gene expression data in terms of gene sets: methodological issues.

Goeman, Bühlmann; (JOURNAL ARTICLE)


Proc Natl Acad Sci U S A

Proteomics of specific treatment-related alterations in Fabry disease: A strategy to identify biological abnormalities.

Moore, Krokhin, Beavis, Ries, Robinson, Goldin, Brady, Wilkins, Schiffmann; (JOURNAL ARTICLE)

Single-enzyme conversion of FMNH2 to 5,6-dimethylbenzimidazole, the lower ligand of B12.

Gray, Escalante-Semerena; (JOURNAL ARTICLE)

Exploring the proton pump mechanism of cytochrome c oxidase in real time.

Belevich, Bloch, Belevich, Wikström, Verkhovsky; (JOURNAL ARTICLE)

Adenovirus-mediated gene delivery into mouse spermatogonial stem cells.

Takehashi, Kanatsu-Shinohara, Inoue, Ogonuki, Miki, Toyokuni, Ogura, Shinohara; (JOURNAL ARTICLE)

Biotin uptake in prokaryotes by solute transporters with an optional ATP-binding cassette-containing module.

Hebbeln, Rodionov, Alfandega, Eitinger; (JOURNAL ARTICLE)

Munc18-1 binds directly to the neuronal SNARE complex.

Dulubova, Khvotchev, Liu, Huryeva, Südhof, Rizo; (JOURNAL ARTICLE)

Cleavage of p65/RelA of the NF-{kappa}B pathway by Chlamydia.

Lad, Li, da Silva Correia, Pan, Gadwal, Ulevitch, Li; (JOURNAL ARTICLE)

Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability.

Trachana, van Wely, Guerrero, Fütterer, Martínez-A; (JOURNAL ARTICLE)

Cholesterol-dependent actin remodeling via RhoA and Rac1 activation by the Streptococcus pneumoniae toxin pneumolysin.

Iliev, Djannatian, Nau, Mitchell, Wouters; (JOURNAL ARTICLE)

Multiscale responses of microbial life to spatial distance and environmental heterogeneity in a patchy ecosystem.

Ramette, Tiedje; (JOURNAL ARTICLE)

Rational redesign of the folding pathway of a modular protein.

Lowe, Itzhaki; (JOURNAL ARTICLE)

Spatial memory and the human hippocampus.

Shrager, Bayley, Bontempi, Hopkins, Squire; (JOURNAL ARTICLE)

Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-{gamma}-inducible gbp2 gene.

Ramsauer, Farlik, Zupkovitz, Seiser, Kröger, Hauser, Decker; (JOURNAL ARTICLE)

Ancient chemoreceptors retain their flexibility.

Parkinson; (JOURNAL ARTICLE)

Reciprocal asymmetry of SYS-1/{beta}-catenin and POP-1/TCF controls asymmetric divisions in Caenorhabditis elegans.

Phillips, Kidd, King, Hardin, Kimble; (JOURNAL ARTICLE)

A synthetic time-delay circuit in mammalian cells and mice.

Weber, Stelling, Rimann, Keller, Daoud-El Baba, Weber, Aubel, Fussenegger; (JOURNAL ARTICLE)

Dual mode of paraxial mesoderm formation during chick gastrulation.

Iimura, Yang, Weijer, Pourquié; (JOURNAL ARTICLE)

Dynamic pressure-induced dendritic and shock crystal growth of ice VI.

Lee, Evans, Yoo; (JOURNAL ARTICLE)

The catalytic subunit of DNA-protein kinase (DNA-PKcs) is not required for Ig class-switch recombination.

Kiefer, Oshinsky, Kim, Nakajima, Bosma, Bosma; (JOURNAL ARTICLE)

Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBP{beta} by GCN5.

Wiper-Bergeron, Salem, Tomlinson, Wu, Haché; (JOURNAL ARTICLE)

Drying a tuberculosis vaccine without freezing.

Wong, Sampson, Germishuizen, Goonesekera, Caponetti, Sadoff, Bloom, Edwards; (JOURNAL ARTICLE)

Molecular analysis of human forearm superficial skin bacterial biota.

Gao, Tseng, Pei, Blaser; (JOURNAL ARTICLE)

Receptors of the protein C activation and activated protein C signaling pathways are colocalized in lipid rafts of endothelial cells.

Bae, Yang, Rezaie; (JOURNAL ARTICLE)

Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation.

Nan, Hou, Maclean, Nasir, Lafuente, Shu, Kriaucionis, Bird; (JOURNAL ARTICLE)

Experiments with probe masses.

Braginsky; (JOURNAL ARTICLE)

Adaptive climatic molecular evolution in wild barley at the Isa defense locus.

Cronin, Bundock, Henry, Nevo; (JOURNAL ARTICLE)

Gene expression and functional evidence of epithelial-to-mesenchymal transition in papillary thyroid carcinoma invasion.

Vasko, Espinosa, Scouten, He, Auer, Liyanarachchi, Larin, Savchenko, Francis, de la Chapelle, Saji, Ringel; (JOURNAL ARTICLE)

CD34+ hematopoietic stem-progenitor cell microRNA expression and function: A circuit diagram of differentiation control.

Georgantas, Hildreth, Morisot, Alder, Liu, Heimfeld, Calin, Croce, Civin; (JOURNAL ARTICLE)

An in vitro and in vivo disconnect uncovered through high-throughput identification of botulinum neurotoxin A antagonists.

Eubanks, Hixon, Jin, Hong, Clancy, Tepp, Baldwin, Malizio, Goodnough, Barbieri, Johnson, Boger, Dickerson, Janda; (JOURNAL ARTICLE)

Evidence for a functional RNA element in the hepatitis C virus core gene.

McMullan, Grakoui, Evans, Mihalik, Puig, Branch, Feinstone, Rice; (JOURNAL ARTICLE)

Establishing the entatic state in folding metallated Pseudomonas aeruginosa azurin.

Zong, Wilson, Shen, Wittung-Stafshede, Mayo, Wolynes; (JOURNAL ARTICLE)

Substrate binding and protein conformational dynamics measured by 2D-IR vibrational echo spectroscopy.

Finkelstein, Ishikawa, Kim, Massari, Fayer; (JOURNAL ARTICLE)

The Saccharomyces cerevisiae 14-3-3 proteins Bmh1 and Bmh2 directly influence the DNA damage-dependent functions of Rad53.

Usui, Petrini; (JOURNAL ARTICLE)

The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.

Suchting, Freitas, le Noble, Benedito, Bréant, Duarte, Eichmann; (JOURNAL ARTICLE)

Pressure dependence of thermal transport properties.

Hofmeister; (JOURNAL ARTICLE)

Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting.

Lobov, Renard, Papadopoulos, Gale, Thurston, Yancopoulos, Wiegand; (JOURNAL ARTICLE)

Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56{delta} subunit.

Ahn, McAvoy, Rakhilin, Nishi, Greengard, Nairn; (JOURNAL ARTICLE)

Enemy release after introduction of disease-resistant genotypes into plant-pathogen systems.

Godfree, Thrall, Young; (JOURNAL ARTICLE)

An obligatory requirement for the heterotrimeric G protein Gi3 in the antiautophagic action of insulin in the liver.

Gohla, Klement, Piekorz, Pexa, Vom Dahl, Spicher, Dreval, Häussinger, Birnbaumer, Nürnberg; (JOURNAL ARTICLE)

Integration within the Felsenstein equation for improved Markov chain Monte Carlo methods in population genetics.

Hey, Nielsen; (JOURNAL ARTICLE)

Characterization of a marine gammaproteobacterium capable of aerobic anoxygenic photosynthesis.

Fuchs, Spring, Teeling, Quast, Wulf, Schattenhofer, Yan, Ferriera, Johnson, Glöckner, Amann; (JOURNAL ARTICLE)

Dissecting hydrophobicity.

Galli; (JOURNAL ARTICLE)

Tissue-driven hypothesis of genomic evolution and sequence-expression correlations.

Gu, Su; (JOURNAL ARTICLE)

Hydrophobic interaction and hydrogen-bond network for a methane pair in liquid water.

Li, Car, Tang, Wingreen; (JOURNAL ARTICLE)

Tissue-specific activity of the blind mole rat and the two nucleotide-mutated mouse {alpha}B-crystallin promoter in transgenic mice.

Li, Hough, Piatigorsky; (JOURNAL ARTICLE)

VEGF kinoid vaccine, a therapeutic approach against tumor angiogenesis and metastases.

Rad, Le Buanec, Paturance, Larcier, Genne, Ryffel, Bensussan, Bizzini, Gallo, Zagury, Uzan; (JOURNAL ARTICLE)

Selective defect of in vivo glycolysis in early Huntington's disease striatum.

Powers, Videen, Markham, McGee-Minnich, Antenor-Dorsey, Hershey, Perlmutter; (JOURNAL ARTICLE)

Metal to metal multiple bonds in ordered assemblies.

Chisholm; (JOURNAL ARTICLE)

A single-molecule barcoding system using nanoslits for DNA analysis.

Jo, Dhingra, Odijk, de Pablo, Graham, Runnheim, Forrest, Schwartz; (JOURNAL ARTICLE)

Arabidopsis intragenomic conserved noncoding sequence.

Thomas, Rapaka, Lyons, Pedersen, Freeling; (JOURNAL ARTICLE)

The EGF repeat and discoidin domain protein, SED1/MFG-E8, is required for mammary gland branching morphogenesis.

Ensslin, Shur; (JOURNAL ARTICLE)

The function neutralizing anti-TrkA antibody MNAC13 reduces inflammatory and neuropathic pain.

Ugolini, Marinelli, Covaceuszach, Cattaneo, Pavone; (JOURNAL ARTICLE)

DDB1 is essential for genomic stability in developing epidermis.

Cang, Zhang, Nicholas, Kim, Zhou, Goff; (JOURNAL ARTICLE)

Ultrafast dynamics of protein collapse from single-molecule photon statistics.

Nettels, Gopich, Hoffmann, Schuler; (JOURNAL ARTICLE)

Bilayer deformation by the Kv channel voltage sensor domain revealed by self-assembly simulations.

Bond, Sansom; (JOURNAL ARTICLE)

The Fas pathway is involved in pancreatic {beta} cell secretory function.

Schumann, Maedler, Franklin, Konrad, Størling, Böni-Schnetzler, Gjinovci, Kurrer, Gauthier, Bosco, Andres, Berney, Greter, Becher, Chervonsky, Halban, Mandrup-Poulsen, Wollheim, Donath; (JOURNAL ARTICLE)

Herpes simplex virus type 1 mediates fusion through a hemifusion intermediate by sequential activity of glycoproteins D, H, L, and B.

Subramanian, Geraghty; (JOURNAL ARTICLE)

Differentiation of ES cells into cerebellar neurons.

Salero, Hatten; (JOURNAL ARTICLE)

An elusive marine photosynthetic bacterium is finally unveiled.

Suzuki, Béjà; (JOURNAL ARTICLE)

Basement membrane remodeling is essential for Drosophila disc eversion and tumor invasion.

Srivastava, Pastor-Pareja, Igaki, Pagliarini, Xu; (JOURNAL ARTICLE)

Polychaete trunk neuroectoderm converges and extends by mediolateral cell intercalation.

Steinmetz, Zelada-Gonzáles, Burgtorf, Wittbrodt, Arendt; (JOURNAL ARTICLE)

A genetic network for the clock of Neurospora crassa.

Yu, Dong, Altimus, Tang, Griffith, Morello, Dudek, Arnold, Schüttler; (JOURNAL ARTICLE)

Properties of glutamate receptors of Alzheimer's disease brain transplanted to frog oocytes.

Bernareggi, Dueñas, Reyes-Ruiz, Ruzzier, Miledi; (JOURNAL ARTICLE)

Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells.

Hsu, Hanson, Kishikawa, Wang, Sawa, Wong; (JOURNAL ARTICLE)

Toward understanding phosphoseryl-tRNACys formation: The crystal structure of Methanococcus maripaludis phosphoseryl-tRNA synthetase.

Kamtekar, Hohn, Park, Schnitzbauer, Sauerwald, Söll, Steitz; (JOURNAL ARTICLE)

A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures.

Mukhopadhyay, Krishnan, Lemke, Lindquist, Deniz; (JOURNAL ARTICLE)

Resistance of human T cell leukemia virus type 1 to APOBEC3G restriction is mediated by elements in nucleocapsid.

Derse, Hill, Princler, Lloyd, Heidecker; (JOURNAL ARTICLE)

Mice cloned from skin cells.

Li, Greco, Guasch, Fuchs, Mombaerts; (JOURNAL ARTICLE)

Prion species barrier between the closely related yeast proteins is detected despite coaggregation.

Chen, Newnam, Chernoff; (JOURNAL ARTICLE)

Critical role of dipeptidyl peptidase I in neutrophil recruitment during the development of experimental abdominal aortic aneurysms.

Pagano, Bartoli, Ennis, Mao, Simmons, Thompson, Pham; (JOURNAL ARTICLE)

Cannabinoid action in the olfactory epithelium.

Czesnik, Schild, Kuduz, Manzini; (JOURNAL ARTICLE)

Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation.

Mustafa, Kumar, Selvakumar, Ho, Ehmsen, Barrow, Amzel, Snyder; (JOURNAL ARTICLE)

Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells.

Fogarty, Emmenegger, Grasfeder, Oliver, Wechsler-Reya; (JOURNAL ARTICLE)

Evolutionary genomics reveals conserved structural determinants of signaling and adaptation in microbial chemoreceptors.

Alexander, Zhulin; (JOURNAL ARTICLE)


N Engl J Med

Stent Thrombosis Redux -- The FDA Perspective.

Farb, Boam; (JOURNAL ARTICLE)

Randomized trial of pulsed corticosteroid therapy for primary treatment of Kawasaki disease.

Newburger, Sleeper, McCrindle, Minich, Gersony, Vetter, Atz, Li, Takahashi, Baker, Colan, Mitchell, Klein, Sundel; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Hyperglycemia in the hospital setting.

Nabhan; (Comment, Letter)

A Pooled Analysis of Data Comparing Sirolimus-Eluting Stents with Bare-Metal Stents.

Spaulding, Daemen, Boersma, Cutlip, Serruys; (JOURNAL ARTICLE)

Inactivated and live attenuated influenza vaccines in young children--how do they compare?

Cox, Bridges; (Comment, Editorial)

Gene-expression-based predictors for breast cancer.

Goetz, Ingle, Couch; (Comment, Letter)

Medicaid revisited--skirmishes over a vast public enterprise.

Iglehart; (Journal Article)

Perioperative stroke.

Selim; (Journal Article)

Is there a role for the endoscopic treatment of pain from chronic pancreatitis?

Elta; (Comment, Editorial)

Long-Term Outcomes with Drug-Eluting Stents versus Bare-Metal Stents in Sweden.

Lagerqvist, James, Stenestrand, Lindbäck, Nilsson, Wallentin; (JOURNAL ARTICLE)

Drug-Eluting Coronary Stents -- Promise and Uncertainty.

Curfman, Morrissey, Jarcho, Drazen; (JOURNAL ARTICLE)

Analysis of 14 Trials Comparing Sirolimus-Eluting Stents with Bare-Metal Stents.

Kastrati, Mehilli, Pache, Kaiser, Valgimigli, Kelbæk, Menichelli, Sabaté, Suttorp, Baumgart, Seyfarth, Pfisterer, Schömig; (JOURNAL ARTICLE)

Inheritance of a cancer-associated MLH1 germ-line epimutation.

Hitchins, Wong, Suthers, Suter, Martin, Hawkins, Ward; (Journal Article, Research Support, Non-U.S. Gov't)

Endoscopic versus surgical drainage of the pancreatic duct in chronic pancreatitis.

Cahen, Gouma, Nio, Rauws, Boermeester, Busch, Stoker, Laméris, Dijkgraaf, Huibregtse, Bruno; (Journal Article, Research Support, Non-U.S. Gov't)

Ranibizumab for neovascular age-related macular degeneration.

Liew, Mitchell; (Comment, Letter)

Medical-process patents.

Klein; (Comment, Letter)

Images in clinical medicine. A hearty finding.

Peddinghaus, Sustento-Reodica; (Journal Article)

Safety and Efficacy of Sirolimus- and Paclitaxel-Eluting Coronary Stents.

Stone, Moses, Ellis, Schofer, Dawkins, Morice, Colombo, Schampaert, Grube, Kirtane, Cutlip, Fahy, Pocock, Mehran, Leon; (JOURNAL ARTICLE)

Images in clinical medicine. Two hearts.

Ghany, de Marchena; (Journal Article)

CT screening for lung cancer.

Gould; (Comment, Letter)

Stent Thrombosis in Randomized Clinical Trials of Drug-Eluting Stents.

Mauri, Hsieh, Massaro, Ho, D'Agostino, Cutlip; (JOURNAL ARTICLE)

Case records of the Massachusetts General Hospital. Case 5-2007. A 53-year-old man with a prosthetic aortic valve and recent onset of fatigue, dyspnea, weight loss, and sweats.

Raoult, Abbara, Jassal, Kradin; (Clinical Conference, Comment, Journal Article)

A closer look at follicular lymphoma.

Staudt; (Journal Article)

The riddle of Kawasaki disease.

Burns; (Comment, Journal Article)

Live attenuated versus inactivated influenza vaccine in infants and young children.

Belshe, Edwards, Vesikari, Black, Walker, Hultquist, Kemble, Connor; (Journal Article, Research Support, Non-U.S. Gov't)

Unanswered Questions -- Drug-Eluting Stents and the Risk of Late Thrombosis.

Maisel; (JOURNAL ARTICLE)

Aspergillus meningitis in Sri Lanka--a post-tsunami effect?

Gunaratne, Wijeyaratne, Seneviratne; (Letter)

XDR tuberculosis--implications for global public health.

Raviglione, Smith; (Journal Article)

Low-carbohydrate diet and coronary heart disease in women.

Esposito, Ciotola, Giugliano; (Comment, Letter)

Genetics and epigenetics--nature's pen-and-pencil set.

Gosden, Feinberg; (Comment, Editorial)

Improving global health--Margaret Chan at the WHO.

Shuchman; (Journal Article)


J Natl Cancer Inst


Lancet

Umbilical cord blood banking Richard Branson's way.

none; (Editorial)

Safety of recommended doses of paracetamol.

Ahmad; (Comment, Letter)

Bazex syndrome (acrokeratosis paraneoplastica).

Poligone, Christensen, Lazova, Heald; (Journal Article)

Japan battles with obesity.

McCurry; (News)

Sexual function in men and women with neurological disorders.

Rees, Fowler, Maas; (Journal Article)

Effectiveness of seven-valent pneumococcal conjugate vaccine - Authors' reply.

O'brien, Levine; (LETTER)

Antimalarial drug combinations in vastly different settings.

Morrow; (Comment, Journal Article)

November, 2006.

none; (JOURNAL ARTICLE)

William Close.

Oransky; (News)

Effectiveness of seven-valent pneumococcal conjugate vaccine.

Mahon, Hsu, Pelton; (Comment, Letter)

Alcohol misuse and traffic accidents.

Caputo, Trevisani, Bernardi; (Comment, Letter)

The USA should allow the free exchange of scientific ideas.

none; (Editorial)

Non-invasive prenatal diagnosis of fetal aneuploidies.

Benachi, Costa; (Comment, Journal Article)

Effectiveness of seven-valent pneumococcal conjugate vaccine - Authors' reply.

Whitney, Zell, Pilishvili; (LETTER)

Dying of diabetes.

Krishnaswami; (Comment, Letter)

Effectiveness of seven-valent pneumococcal conjugate vaccine.

Beutels, Van Damme; (Comment, Letter)

Ten pieces of free software every doctor should have.

Magos, Mehta, Tsimpanakos; (Letter)

Dying of diabetes - Author's reply.

Gale; (LETTER)

Effect of azithromycin and clarithromycin therapy on pharyngeal carriage of macrolide-resistant streptococci in healthy volunteers: a randomised, double-blind, placebo-controlled study.

Malhotra-Kumar, Lammens, Coenen, Van Herck, Goossens; (Journal Article, Research Support, Non-U.S. Gov't)

In defence of Charcot, Curie, and Wittmann.

van Gijn; (Letter)

A non-invasive test for prenatal diagnosis based on fetal DNA present in maternal blood: a preliminary study.

Dhallan, Guo, Emche, Damewood, Bayliss, Cronin, Barry, Betz, Franz, Gold, Vallecillo, Varney; (Journal Article, Research Support, Non-U.S. Gov't)

Narcolepsy with cataplexy.

Dauvilliers, Arnulf, Mignot; (Journal Article)

Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.

Laine, Curtis, Cryer, Kaur, Cannon; (Journal Article, Research Support, Non-U.S. Gov't)

Does helminth elimination promote or prevent malaria?

Specht, Hoerauf; (Journal Article)

The right to health: more than rhetoric.

none; (Editorial)

Attention prescribers: be careful with antibiotics.

Dancer; (Comment, Journal Article)

Microarray genetic screening: a prenatal roadblock for life?

Shuster; (Journal Article)

From fact to fiction.

Pini, Osmond; (JOURNAL ARTICLE)

Dying of diabetes.

Hirst; (Comment, Letter)

Do COX-2 inhibitors give enough gastrointestinal protection?

Drenth, Verheugt; (Comment, Journal Article)

Artemether-lumefantrine versus amodiaquine plus sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Burkina Faso: a randomised non-inferiority trial.

Zongo, Dorsey, Rouamba, Tinto, Dokomajilar, Guiguemde, Rosenthal, Ouedraogo; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

The modern researcher and the peacock's tail.

Whiteman; (Journal Article)

Mental health in development: re-emphasising the link.

Gureje, Jenkins; (Journal Article)

Blood safety and democracy.

Cheraghali; (Letter)

US health-care providers go "green".

Bristol; (News)

Academic apartheid by the back door.

Khan; (Letter)


Expert Rev Mol Diagn