Nature

Developing resistance.

none; (Editorial)

Volcanoes: interpreting inclusive evidence.

Hammer; (News)

Ecology: mechanisms for consumer diversity.

Yoshida, Jones, Ellner, Hairston; (Comment, Journal Article)

Complex social behaviour derived from maternal reproductive traits.

Amdam, Csondes, Fondrk, Page; (Journal Article, Research Support, Non-U.S. Gov't , Research Support, U.S. Gov't, Non-P.H.S. )

Planetary science: the ferryman casts his shadow.

Tholen; (Comment, News)

Purification and unique properties of mammary epithelial stem cells.

Stingl, Eirew, Ricketson, Shackleton, Vaillant, Choi, Li, Eaves; (Journal Article, Research Support, Non-U.S. Gov't )

Sound science.

none; (Editorial)

Developmental neuroscience: two gradients are better than one.

Luo; (Comment, News)

No new start at Los Alamos.

none; (Editorial)

Oceanography: a phosphate alternative.

Sańudo-Wilhelmy; (Comment, News)

Intelligent design verdict set to sway other cases.

Marris; (News)

Our Universe: outrageous fortune.

Brumfiel; (News)

Three-dimensional brittle shear fracturing by tensile crack interaction.

Healy, Jones, Holdsworth; (Journal Article)

Phosphonate utilization by the globally important marine diazotroph Trichodesmium.

Dyhrman, Chappell, Haley, Moffett, Orchard, Waterbury, Webb; (Journal Article, Research Support, Non-U.S. Gov't , Research Support, U.S. Gov't, Non-P.H.S. )

Radioactive 26Al from massive stars in the Galaxy.

Diehl, Halloin, Kretschmer, Lichti, Schönfelder, Strong, von Kienlin, Wang, Jean, Knödlseder, Roques, Weidenspointner, Schanne, Hartmann, Winkler, Wunderer; (Journal Article)

Power clashes limit science and reflect archaic values.

Uriarte, Weathers, Eviner; (Comment, Letter)

Mechanochemical analysis of DNA gyrase using rotor bead tracking.

Gore, Bryant, Stone, Nöllmann, Cozzarelli, Bustamante; (Journal Article, Research Support, N.I.H., Extramural , Research Support, Non-U.S. Gov't , Research Support, U.S. Gov't, Non-P.H.S. )

Potentiation of neuroblastoma metastasis by loss of caspase-8.

Stupack, Teitz, Potter, Mikolon, Houghton, Kidd, Lahti, Cheresh; (Journal Article, Research Support, N.I.H., Extramural , Research Support, Non-U.S. Gov't )

Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation.

Yin, Wen, Paterson, Lamb, Jardetzky; (Journal Article, Research Support, N.I.H., Extramural , Research Support, Non-U.S. Gov't )

Power games cause sparks in physics, but biologists have learnt from evolution.

Hietz, Winkler; (Comment, Letter)

Croatian scientists call for openness over funding.

Abbott; (News)

Fisheries: deep-sea fishes qualify as endangered.

Devine, Baker, Haedrich; (Journal Article)

Death sentence revoked for HIV workers in Libya.

none; (News)

Structural diversity in binary nanoparticle superlattices.

Shevchenko, Talapin, Kotov, O'Brien, Murray; (Journal Article)

Charon's radius and atmospheric constraints from observations of a stellar occultation.

Gulbis, Elliot, Person, Adams, Babcock, Emilio, Gangestad, Kern, Kramer, Osip, Pasachoff, Souza, Tuvikene; (Journal Article)

Abrupt reversal in ocean overturning during the Palaeocene/Eocene warm period.

Nunes, Norris; (Historical Article, Journal Article, Research Support, U.S. Gov't, Non-P.H.S. )

More than just hot air?

none; (Journal Article)

Ethiopia: Awash with fossils.

Dalton; (News)

Charon's size and an upper limit on its atmosphere from a stellar occultation.

Sicardy, Bellucci, Gendron, Lacombe, Lacour, Lecacheux, Lellouch, Renner, Pau, Roques, Widemann, Colas, Vachier, Martins, Ageorges, Hainaut, Marco, Beisker, Hummel, Feinstein, Levato, Maury, Frappa, Gaillard, Lavayssičre, Di Sora, Mallia, Masi, Behrend, Carrier, Mousis, Rousselot, Alvarez-Candal, Lazzaro, Veiga, Andrei, Assafin, da Silva Neto, Jacques, Pimentel, Weaver, Lecampion, Doncel, Momiyama, Tancredi; (Journal Article)

Bias may be unintentional but it's still there.

Chen, Hsieh; (Comment, Letter)

Science is an adventure, not a battle.

Kleinfeld; (Comment, Letter)

Blow follows blow for stem-cell work.

Cyranoski; (News)

Los Alamos bosses ditched after decade of scandals.

Marris; (News)

Biological physics: harmonies from noise.

Springer, Paulsson; (News)

Generation of a functional mammary gland from a single stem cell.

Shackleton, Vaillant, Simpson, Stingl, Smyth, Asselin-Labat, Wu, Lindeman, Visvader; (Journal Article, Research Support, Non-U.S. Gov't )

Mashups mix data into global service.

Butler; (News)

RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP.

Dumont, Cheng, Serebrov, Beran, Tinoco, Pyle, Bustamante; (Journal Article, Research Support, N.I.H., Extramural , Research Support, Non-U.S. Gov't )


Science


Nature Methods


Nature Biotechnology

Derivation of human embryonic stem cells in defined conditions.

Ludwig, Levenstein, Jones, Berggren, Mitchen, Frane, Crandall, Daigh, Conard, Piekarczyk, Llanas, Thomson; (Journal Article, Research Support, N.I.H., Extramural )


Nature Medicine

Scientists, activists sue South Africa's AIDS 'denialists'.

Watson; (News)

RBP4, an unexpected adipokine.

Tamori, Sakaue, Kasuga; (News)

The humoral side of insulin resistance.

Lazar; (News)

Improving metabolism by increasing energy expenditure.

Auwerx; (News)

Epidemiologic and economic consequences of the global epidemics of obesity and diabetes.

Yach, Stuckler, Brownell; (Journal Article)

Diabetes research investment in the European Union.

Halban, Ferrannini, Nerup; (Journal Article)

Hormone in the hot seat.

Mandavilli; (News)

Low morale at US agency revives dormant scientist group.

Mack; (News)

Growing safety concerns stir caution on gastric bypass surgery.

Wadman; (News)

Combating diabetes and obesity in Japan.

Yazaki, Kadowaki; (Journal Article)

Sirt1: a metabolic master switch that modulates lifespan.

Leibiger, Berggren; (News)

South Korean scandal rocks stem cell community.

Cyranoski; (News)

Diabetes and obesity: the twin epidemics.

Smyth, Heron; (Journal Article)

US ponders unlocking the gates to prisoner research.

Waltz; (News)

Reshuffle at infectious disease center ruffles many feathers.

Marris; (News)

A channel to neurodegeneration.

Deutch, Winder; (News)

Are all fats created equal?

Murphy, Bloom; (News)

Stressed out about obesity and insulin resistance.

de Luca, Olefsky; (News)

Vessel tone and remodeling.

Burnstock; (Comment, News)

Rimonabant adds appetizing choice to slim obesity market.

Wadman; (News)

Inbred Israeli families aid research on rare diseases.

Vikhanski; (News)

Metabolic syndrome.

none; (Journal Article)

When the Clock stops ticking, metabolic syndrome explodes.

Staels; (News)

How diabetes went to our heads.

Seeley, Tschöp; (News)

ARNT misbehavin' in diabetic beta cells.

Czech; (News)

The tangled path to glucose production.

Matsumoto, Accili; (News)

One enzyme inactivates two antibiotics.

Klugman, Levin; (Comment, News)

Did a muscle fuel gauge conquer the brain?

Pocai, Muse, Rossetti; (News)

NIH research on obesity and type 2 diabetes: providing the scientific evidence base for actions to improve health.

Spiegel, Nabel; (Journal Article)

Klotho-induced insulin resistance: a blessing in disguise?

Unger; (News)

Foxa2, a novel transcriptional regulator of insulin sensitivity.

Puigserver, Rodgers; (News)

New rules propose greater scrutiny for NIH grant recipients.

Dove; (News)

Breaking the rules of cancer.

Shaffer, Pandolfi; (News)

Decoy receptor springs to life and eases fibrosis.

MacDonald; (Comment, News)

Fast predators or fast food, the fit still survive.

Bernal-Mizrachi, Semenkovich; (News)

MicroRNAs: 'ribo-regulators' of glucose homeostasis.

Gauthier, Wollheim; (News)

Developmental programming of the hypothalamus: a matter of fat.

Horvath, Bruning; (News)

Unchecked by guidelines, Indian stem cell scientists rush ahead.

Padma; (News)

Profile: Janet Rowley.

Novak; (Biography, Historical Article, Journal Article)


Nature Genetics

Comparative analysis of chimpanzee and human Y chromosomes unveils complex evolutionary pathway.

Kuroki, Toyoda, Noguchi, Taylor, Itoh, Kim, Kim, Choi, Kim, Choi, Kim, Satta, Saitou, Yamada, Morishita, Hattori, Sakaki, Park, Fujiyama; (Comparative Study , Journal Article, Research Support, Non-U.S. Gov't )


Molecular Medicine


Proteomics


Nature Drug Discovery


BMC Bioinformatics

Fast-Find: a novel computational approach to analyzing combinatorial motifs.

Hamady, Peden, Knight, Singh; (Journal Article, Research Support, N.I.H., Extramural , Research Support, Non-U.S. Gov't )


Bioinformatics

A multi-step approach to time series analysis and gene expression clustering.

Amato, Ciaramella, Deniskina, Del Mondo, di Bernardo, Donalek, Longo, Mangano, Miele, Raiconi, Staiano, Tagliaferri; (Evaluation Studies, Journal Article)

ANDY: a general, fault-tolerant tool for database searching on computer clusters.

Smith, Chandonia, Brenner; (Journal Article, Research Support, N.I.H., Extramural , Research Support, Non-U.S. Gov't , Research Support, U.S. Gov't, Non-P.H.S. )

A non-linear optimization procedure to estimate distances and instantaneous substitution rate matrices under the GTR model.

Catanzaro, Pesenti, Milinkovitch; (Journal Article)

A regularized discriminative model for the prediction of protein-peptide interactions.

Lehrach, Husmeier, Williams; (Journal Article, Research Support, Non-U.S. Gov't )

OPM: orientations of proteins in membranes database.

Lomize, Lomize, Pogozheva, Mosberg; (Journal Article, Research Support, N.I.H., Extramural , Research Support, Non-U.S. Gov't )

BuchneraBASE: a post-genomic resource for Buchnera sp. APS.

Prickett, Page, Douglas, Thomas; (Journal Article)

ORegAnno: an open access database and curation system for literature-derived promoters, transcription factor binding sites and regulatory variation.

Montgomery, Griffith, Sleumer, Bergman, Bilenky, Pleasance, Prychyna, Zhang, Jones; (Journal Article, Research Support, Non-U.S. Gov't )


Proc Natl Acad Sci U S A

Demonstration of cue recruitment: change in visual appearance by means of Pavlovian conditioning.

Haijiang, Saunders, Stone, Backus; (Journal Article, Research Support, N.I.H., Extramural , Research Support, Non-U.S. Gov't )

Evidence of a false thumb in a fossil carnivore clarifies the evolution of pandas.

Salesa, Antón, Peigné, Morales; (Journal Article, Research Support, Non-U.S. Gov't )

Spread dynamics of invasive species.

Arim, Abades, Neill, Lima, Marquet; (Journal Article)

Division accuracy in a stochastic model of Min oscillations in Escherichia coli.

Kerr, Levine, Sejnowski, Rappel; (Journal Article, Research Support, N.I.H., Extramural , Research Support, Non-U.S. Gov't , Research Support, U.S. Gov't, Non-P.H.S. )

Enhancement of plasmid-mediated gene therapy for muscular dystrophy by directed plasmid integration.

Bertoni, Jarrahian, Wheeler, Li, Olivares, Calos, Rando; (Journal Article, Research Support, Non-U.S. Gov't )

Linoleic acid hydroperoxide reacts with hypochlorous acid, generating peroxyl radical intermediates and singlet molecular oxygen.

Miyamoto, Martinez, Rettori, Augusto, Medeiros, Di Mascio; (Journal Article, Research Support, Non-U.S. Gov't )

Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis.

Manjunatha, Boshoff, Dowd, Zhang, Albert, Norton, Daniels, Dick, Pang, Barry; (Journal Article, Research Support, N.I.H., Intramural )

Packing defects as selectivity switches for drug-based protein inhibitors.

Fernández, Scott, Berry; (Journal Article, Research Support, N.I.H., Extramural , Retracted Publication)

Autoantibodies to myelin basic protein catalyze site-specific degradation of their antigen.

Ponomarenko, Durova, Vorobiev, Belogurov, Kurkova, Petrenko, Telegin, Suchkov, Kiselev, Lagarkova, Govorun, Serebryakova, Avalle, Tornatore, Karavanov, Morse, Thomas, Friboulet, Gabibov; (Journal Article, Research Support, N.I.H., Intramural , Research Support, Non-U.S. Gov't )

Punishing and abstaining for public goods.

Brandt, Hauert, Sigmund; (Journal Article)

Constitutive activation of MKK6 in chondrocytes of transgenic mice inhibits proliferation and delays endochondral bone formation.

Zhang, Murakami, Coustry, Wang, de Crombrugghe; (Journal Article, Research Support, N.I.H., Extramural , Research Support, Non-U.S. Gov't )

Whorf hypothesis is supported in the right visual field but not the left.

Gilbert, Regier, Kay, Ivry; (Journal Article, Research Support, N.I.H., Extramural , Research Support, U.S. Gov't, Non-P.H.S. )

MAX1, a regulator of the flavonoid pathway, controls vegetative axillary bud outgrowth in Arabidopsis.

Lazar, Goodman; (Journal Article, Research Support, Non-U.S. Gov't )

Synchronous dynamic brain networks revealed by magnetoencephalography.

Langheim, Leuthold, Georgopoulos; (Journal Article, Research Support, Non-U.S. Gov't , Research Support, U.S. Gov't, Non-P.H.S. )

Infection, inflammation, height, and longevity.

Crimmins, Finch; (Historical Article, Journal Article, Research Support, N.I.H., Extramural , Research Support, Non-U.S. Gov't )

Preclinical and phase I clinical trial of blockade of IL-15 using Mikbeta1 monoclonal antibody in T cell large granular lymphocyte leukemia.

Morris, Janik, White, Fleisher, Brown, Tsudo, Goldman, Bryant, Petrus, Top, Lee, Gao, Waldmann; (Clinical Trial, Phase I, Journal Article, Research Support, N.I.H., Intramural )

PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells.

Pasqualucci, Kitaura, Gu, Dalla-Favera; (Journal Article, Research Support, N.I.H., Extramural , Research Support, Non-U.S. Gov't )


N Engl J Med

Images in clinical medicine. Black hairy tongue.

Korber, Dissemond; (Case Reports, Journal Article)

Ketoacidosis during a low-carbohydrate diet.

Shah, Isley; (Case Reports, Letter)

Drotrecogin alfa (activated) in severe sepsis.

Baillie, Murray; (Comment, Letter)

Drotrecogin alfa (activated) in severe sepsis.

Friedrich; (Comment, Letter)

Antibacterial prophylaxis in patients with cancer and neutropenia.

Ito, Tegtmeier, O'Donnell; (Comment, Letter)

Is our behavior written in our genes?

Drayna; (Journal Article)

Gamma-hydroxybutyric acid in hair.

Mion, Tourtier, Diraison; (Comment, Letter)

Genetic modifiers in cystic fibrosis.

Stanke, Tümmler, Becker; (Comment, Letter)

Antibacterial prophylaxis in patients with cancer and neutropenia.

Freifeld, Sepkowitz, Martino, Steven, Billingham, Cullen, Baden; (Comment, Letter)

Antibacterial prophylaxis in patients with cancer and neutropenia.

Eller, Pechlaner; (Comment, Letter)

Drotrecogin alfa (activated) in severe sepsis.

LaRosa; (Comment, Letter)

Safety and efficacy of an attenuated vaccine against severe rotavirus gastroenteritis.

Ruiz-Palacios, Pérez-Schael, Velázquez, Abate, Breuer, Clemens, Cheuvart, Espinoza, Gillard, Innis, Cervantes, Linhares, López, Macías-Parra, Ortega-Barría, Richardson, Rivera-Medina, Rivera, Salinas, Pavía-Ruz, Salmerón, Rüttimann, Tinoco, Rubio, Nuńez, Guerrero, Yarzábal, Damaso, Tornieporth, Sáez-Llorens, Vergara, Vesikari, Bouckenooghe, Clemens, De Vos, O'Ryan; (Clinical Trial, Phase III, Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't )

Inhibiting inflammation in rheumatoid arthritis.

Firestein; (Journal Article)

Genetic modifiers in cystic fibrosis.

Rossi, Rossi; (Comment, Letter)

Autoimmune hepatitis.

Krawitt; (Journal Article, Review)

Clinical problem-solving. Needle in a haystack.

Polu, Wolf; (Case Reports, Journal Article)

The big chill--inserting the DEA into end-of-life care.

Quill, Meier; (Journal Article)

The promise of new rotavirus vaccines.

Glass, Parashar; (Comment, Editorial)

Antibacterial prophylaxis in patients with cancer and neutropenia.

Castagna, Santoro; (Comment, Letter)

Intraperitoneal chemotherapy comes of age.

Cannistra; (Comment, Editorial)

Intraperitoneal cisplatin and paclitaxel in ovarian cancer.

Armstrong, Bundy, Wenzel, Huang, Baergen, Lele, Copeland, Walker, Burger; (Clinical Trial, Phase III, Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, N.I.H., Extramural )

Images in clinical medicine. Pellegrini-Stieda syndrome.

Altschuler, Bryce; (Case Reports, Journal Article)

Community-acquired bacterial meningitis in adults.

van de Beek, de Gans, Tunkel, Wijdicks; (Journal Article, Review)

Antibacterial prophylaxis in patients with cancer and neutropenia.

Pasqualotto, Rosa, Machado; (Comment, Letter)

Normal fasting plasma glucose levels and type 2 diabetes.

Gambino, Reichberg, Schwartz; (Comment, Letter)

Searching for the right search--reaching the medical literature.

Steinbrook; (Journal Article)

Antibacterial prophylaxis in patients with cancer and neutropenia.

Almyroudis, Segal; (Comment, Letter)

Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine.

Vesikari, Matson, Dennehy, Van Damme, Santosham, Rodriguez, Dallas, Heyse, Goveia, Black, Shinefield, Christie, Ylitalo, Itzler, Coia, Onorato, Adeyi, Marshall, Gothefors, Campens, Karvonen, Watt, O'Brien, DiNubile, Clark, Boslego, Offit, Heaton; (Journal Article, Multicenter Study, Randomized Controlled Trial)


J Natl Cancer Inst

Reliability of self-reported family history of cancer in a large case-control study of lymphoma.

Chang, Smedby, Hjalgrim, Glimelius, Adami; (Journal Article, Research Support, N.I.H., Extramural , Research Support, Non-U.S. Gov't )

Stat bite: U.S. incidence of childhood Hodgkin lymphoma by age group, 1975-2002.

none; (Journal Article)

Qualified health claim rulings leave little leeway for label language.

Vastag; (News)

Cancer survivorship--genetic susceptibility and second primary cancers: research strategies and recommendations.

Travis, Rabkin, Brown, Allan, Alter, Ambrosone, Begg, Caporaso, Chanock, DeMichele, Figg, Gospodarowicz, Hall, Hisada, Inskip, Kleinerman, Little, Malkin, Ng, Offit, Pui, Robison, Rothman, Shields, Strong, Taniguchi, Tucker, Greene; (Journal Article, Research Support, N.I.H., Extramural , Research Support, N.I.H., Intramural , Research Support, Non-U.S. Gov't , Review)

Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication.

Aghi, Rabkin, Martuza; (Journal Article, Research Support, N.I.H., Extramural )

Stats on statins: anything but static.

McLaughlin; (Comment, Editorial)

Texas case raises questions about Hodgkin lymphoma treatment in children.

Vanchieri; (News)

Survival effects of postmastectomy adjuvant radiation therapy using biologically equivalent doses: a clinical perspective.

Gebski, Lagleva, Keech, Simes, Langlands; (Journal Article, Meta-Analysis, Research Support, Non-U.S. Gov't )

Is nanotechnology ready for primetime?

Brower; (News)

Carbonated soft drink consumption and risk of esophageal adenocarcinoma.

Mayne, Risch, Dubrow, Chow, Gammon, Vaughan, Borchardt, Schoenberg, Stanford, West, Rotterdam, Blot, Fraumeni; (Journal Article, Multicenter Study, Research Support, N.I.H., Extramural , Research Support, N.I.H., Intramural )

Postmastectomy radiotherapy: quality counts!

Prosnitz, Marks; (Comment, Editorial)

Identity crisis: finding, defining, and integrating biomarkers still a challenge.

Twombly; (News)

Autoimmune and chronic inflammatory disorders and risk of non-Hodgkin lymphoma by subtype.

Smedby, Hjalgrim, Askling, Chang, Gregersen, Porwit-MacDonald, Sundström, Akerman, Melbye, Glimelius, Adami; (Journal Article, Research Support, N.I.H., Extramural , Research Support, Non-U.S. Gov't )

Cholesterol-lowering drugs and colorectal cancer incidence in a large United States cohort.

Jacobs, Rodriguez, Brady, Connell, Thun, Calle; (Journal Article)


Lancet


Expert Rev Mol Diagn