Nature

Taussig, Stoevesandt, Borrebaeck, Bradbury, Cahill, Cambillau, de Daruvar, Dübel, Eichler, Frank, Gibson, Gloriam, Gold, Herberg, Hermjakob, Hoheisel, Joos, Kallioniemi, Koegll, Konthur, Korn, Kremmer, Krobitsch, Landegren, van der Maarel, McCafferty, Muyldermans, Nygren, Palcy, Plückthun, Polic, Przybylski, Saviranta, Sawyer, Sherman, Skerra, Templin, Ueffing, Uhlén; (Journal Article)

4D brain signaling.

Marandi, Konnerth; (Journal Article)

Widening the protein crystallization bottleneck.

Doerr; (Journal Article)

Six degrees of separation.

Kiermer; (Journal Article)

Adult stem cells come up short.

Potash; (Journal Article)

The shape of things.

Eisenstein; (Journal Article)

An Escherichia coli expression-based method for heme substitution.

Woodward, Martin, Marletta; (Journal Article)

From cryo-EM, multiple protein structures in one shot.

Sigworth; (Journal Article)

BRET analysis of GPCR oligomerization: newer does not mean better.

James, Davis; (Journal Article)

Nature Biotechnology

Absolute protein expression profiling estimates the relative contributions of transcriptional and translational regulation.

Lu, Vogel, Wang, Yao, Marcotte; (JOURNAL ARTICLE)

F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses.

Poueymirou, Auerbach, Frendewey, Hickey, Escaravage, Esau, Doré, Stevens, Adams, Dominguez, Gale, Yancopoulos, Dechiara, Valenzuela; (JOURNAL ARTICLE)

Nature Medicine

Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging.

Lee, Huh, Jun, Seo, Jang, Song, Kim, Cho, Yoon, Suh, Cheon; (JOURNAL ARTICLE)

Calreticulin exposure dictates the immunogenicity of cancer cell death.

Obeid, Tesniere, Ghiringhelli, Fimia, Apetoh, Perfettini, Castedo, Mignot, Panaretakis, Casares, Métivier, Larochette, van Endert, Ciccosanti, Piacentini, Zitvogel, Kroemer; (JOURNAL ARTICLE)

Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants.

Fischer, Perkins, Theiler, Bhattacharya, Yusim, Funkhouser, Kuiken, Haynes, Letvin, Walker, Hahn, Korber; (JOURNAL ARTICLE)

Nature Genetics

Touching base.

none; (Journal Article)

Lessons in the genomic diversity of malaria.

none; (Journal Article)

Awesome, in brief.

Klar; (Journal Article)

Chaotic license for genetic instability and cancer.

Dutta; (Journal Article)

Corrigendum: Cxorf6 is a causative gene for hypospadias.

Fukami, Wada, Miyabayashi, Nishino, Hasegawa, Camerino, Kretz, Buj-Bello, Laporte, Yamada, Morohashi, Ogata; (Journal Article)

HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease).

Klein, Grudzien, Appaswamy, Germeshausen, Sandrock, Schäffer, Rathinam, Boztug, Schwinzer, Rezaei, Bohn, Melin, Carlsson, Fadeel, Dahl, Palmblad, Henter, Zeidler, Grimbacher, Welte; (Journal Article)

Toward a malaria haplotype map.

Carlton; (Journal Article)

Sending out an SOS.

Shannon, Bollag; (Journal Article)

Research highlights.

none; (Journal Article)

Following the herd.

Wooding; (Journal Article)

The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy.

Fischer, Lefèvre, Morava, Mussini, Laforêt, Negre-Salvayre, Lathrop, Salvayre; (Journal Article)

Telomeres, p21 and the cancer-aging hypothesis.

Bell, Sharpless; (Journal Article)

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database.

Bertram, McQueen, Mullin, Blacker, Tanzi; (Journal Article)

Molecular Medicine

Proteomics

Nature Drug Discovery

BMC Bioinformatics

How repetitive are genomes?

Haubold, Wiehe; (JOURNAL ARTICLE)

HaploRec: Efficient and accurate large-scale reconstruction of haplotypes.

Eronen, Geerts, Toivonen; (JOURNAL ARTICLE)

Recursive gene selection based on maximum margin criterion: a comparison with SVM-RFE.

Niijima, Kuhara; (JOURNAL ARTICLE)

Bioinformatics

The discovery of transcriptional modules by a two-stage matrix decomposition approach.

Li, Sun, Zhan; (JOURNAL ARTICLE)

Proc Natl Acad Sci U S A

Eukaryotic operon-like transcription of functionally related genes in Drosophila.

Ben-Shahar, Nannapaneni, Casavant, Scheetz, Welsh; (JOURNAL ARTICLE)

Risk assessment for invasive species produces net bioeconomic benefits.

Keller, Lodge, Finnoff; (JOURNAL ARTICLE)

Activity-dependent neurotransmitter-receptor matching at the neuromuscular junction.

Borodinsky, Spitzer; (JOURNAL ARTICLE)

Coupled transport at the nanoscale: The unreasonable effectiveness of equilibrium theory.

Astumian; (JOURNAL ARTICLE)

N-formylation of lysine in histone proteins as a secondary modification arising from oxidative DNA damage.

Jiang, Zhou, Taghizadeh, Dong, Dedon; (JOURNAL ARTICLE)

Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2.

Saito, Hirai, Loo, Owen, Johnson, Sinha, Akira, Fujita, Gale; (JOURNAL ARTICLE)

Oxygen isotopic composition of carbon dioxide in the middle atmosphere.

Liang, Blake, Lewis, Yung; (JOURNAL ARTICLE)

Lung development and repair: Contribution of the ciliated lineage.

Rawlins, Ostrowski, Randell, Hogan; (JOURNAL ARTICLE)

A unique configuration of genome-wide DNA methylation patterns in the testis.

Oakes, La Salle, Smiraglia, Robaire, Trasler; (JOURNAL ARTICLE)

D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum.

Rashid, So, Kong, Furtak, El-Ghundi, Cheng, O'dowd, George; (JOURNAL ARTICLE)

Chemically engineered extracts as an alternative source of bioactive natural product-like compounds.

López, Ramallo, Gonzalez Sierra, Zacchino, Furlan; (JOURNAL ARTICLE)

Oxidized messenger RNA induces translation errors.

Tanaka, Chock, Stadtman; (JOURNAL ARTICLE)

A singular enzymatic megacomplex from Bacillus subtilis.

Straight, Fischbach, Walsh, Rudner, Kolter; (JOURNAL ARTICLE)

Microinversions in mammalian evolution.

Chaisson, Raphael, Pevzner; (Journal Article)

The Iranian petroleum crisis and United States national security.

Stern; (JOURNAL ARTICLE)

Independent control of grafting density and conformation of single-stranded DNA brushes.

Opdahl, Petrovykh, Kimura-Suda, Tarlov, Whitman; (JOURNAL ARTICLE)

Short wavelength topography on the inner-core boundary.

Cao, Masson, Romanowicz; (JOURNAL ARTICLE)

Long-lasting and transmission-blocking activity of antibodies to Plasmodium falciparum elicited in mice by protein conjugates of Pfs25.

Kubler-Kielb, Majadly, Wu, Narum, Guo, Miller, Shiloach, Robbins, Schneerson; (JOURNAL ARTICLE)

Structure of aspartoacylase, the brain enzyme impaired in Canavan disease.

Bitto, Bingman, Wesenberg, McCoy, Phillips; (JOURNAL ARTICLE)

A neural basis for inference in perceptual ambiguity.

Sterzer, Kleinschmidt; (JOURNAL ARTICLE)

Cyclin-dependent kinase 5 modulates nociceptive signaling through direct phosphorylation of transient receptor potential vanilloid 1.

Pareek, Keller, Kesavapany, Agarwal, Kuner, Pant, Iadarola, Brady, Kulkarni; (JOURNAL ARTICLE)

Insights into finding a mismatch through the structure of a mispaired DNA bound by a rhodium intercalator.

Pierre, Kaiser, Barton; (JOURNAL ARTICLE)

Structure and quantum chemical characterization of chloroperoxidase compound 0, a common reaction intermediate of diverse heme enzymes.

Kühnel, Derat, Terner, Shaik, Schlichting; (JOURNAL ARTICLE)

Toxin-antitoxin systems are ubiquitous and plasmid-encoded in vancomycin-resistant enterococci.

Moritz, Hergenrother; (JOURNAL ARTICLE)

Differential fitness costs of reproduction between the sexes.

Penn, Smith; (JOURNAL ARTICLE)

Multiple-motor based transport and its regulation by Tau.

Vershinin, Carter, Razafsky, King, Gross; (JOURNAL ARTICLE)

Structural basis for intramembrane proteolysis by rhomboid serine proteases.

Ben-Shem, Fass, Bibi; (JOURNAL ARTICLE)

Monomer adds to preformed structured oligomers of A{beta}-peptides by a two-stage dock-lock mechanism.

Nguyen, Li, Stock, Straub, Thirumalai; (JOURNAL ARTICLE)

Evidence of the existence of the low-density liquid phase in supercooled, confined water.

Mallamace, Broccio, Corsaro, Faraone, Majolino, Venuti, Liu, Mou, Chen; (JOURNAL ARTICLE)

Par4 is required for platelet thrombus propagation but not fibrin generation in a mouse model of thrombosis.

Vandendries, Hamilton, Coughlin, Furie, Furie; (JOURNAL ARTICLE)

H2A.Z contributes to the unique 3D structure of the centromere.

Greaves, Rangasamy, Ridgway, Tremethick; (JOURNAL ARTICLE)

Nuclear IKK activity leads to dysregulated Notch-dependent gene expression in colorectal cancer.

Fernández-Majada, Aguilera, Villanueva, Vilardell, Robert-Moreno, Aytés, Real, Capella, Mayo, Espinosa, Bigas; (JOURNAL ARTICLE)

Functionally important glycosyltransferase gain and loss during catarrhine primate emergence.

Koike, Uddin, Wildman, Gray, Trucco, Starzl, Goodman; (JOURNAL ARTICLE)

Parasitic inhibition of cell death facilitates symbiosis.

Pannebakker, Loppin, Elemans, Humblot, Vavre; (JOURNAL ARTICLE)

Mouse oocytes within germ cell cysts and primordial follicles contain a Balbiani body.

Pepling, Wilhelm, O'hara, Gephardt, Spradling; (JOURNAL ARTICLE)

Penetrating arterioles are a bottleneck in the perfusion of neocortex.

Nishimura, Schaffer, Friedman, Lyden, Kleinfeld; (JOURNAL ARTICLE)

Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants.

Schuster-Gossler, Cordes, Gossler; (JOURNAL ARTICLE)

Genetic regulation of patterned tubular branching in Drosophila.

Hatton-Ellis, Ainsworth, Sushama, Wan, Vijayraghavan, Skaer; (JOURNAL ARTICLE)

Conserved markers of fetal pancreatic epithelium permit prospective isolation of islet progenitor cells by FACS.

Sugiyama, Rodriguez, McLean, Kim; (JOURNAL ARTICLE)

Resolution limit in community detection.

Fortunato, Barthélemy; (JOURNAL ARTICLE)

Ungulate herbivory: Indirect effects cascade into the treetops.

Larson, Paine; (JOURNAL ARTICLE)

Herbivore-initiated interaction cascades and their modulation by productivity in an African savanna.

Pringle, Young, Rubenstein, McCauley; (JOURNAL ARTICLE)

Inhibitory complex of the transmembrane ammonia channel, AmtB, and the cytosolic regulatory protein, GlnK, at 1.96 A.

Gruswitz, O'connell, Stroud; (JOURNAL ARTICLE)

The tetraspanin CD9 mediates lateral association of MHC class II molecules on the dendritic cell surface.

Unternaehrer, Chow, Pypaert, Inaba, Mellman; (JOURNAL ARTICLE)

Antitumor NK activation induced by the Toll-like receptor 3-TICAM-1 (TRIF) pathway in myeloid dendritic cells.

Akazawa, Ebihara, Okuno, Okuda, Shingai, Tsujimura, Takahashi, Ikawa, Okabe, Inoue, Okamoto-Tanaka, Ishizaki, Miyoshi, Matsumoto, Seya; (JOURNAL ARTICLE)

N Engl J Med

Eculizumab in paroxysmal nocturnal hemoglobinuria.

Pride; (Comment, Letter)

Uncovering an epidemic--screening for mental illness in teens.

Friedman; (Journal Article)

Case records of the Massachusetts General Hospital. Case 40-2006. A 64-year-old man with anemia and a low level of HDL cholesterol.

Murali, Kratz, Finberg; (Clinical Conference, Journal Article)

Enoxaparin in elective percutaneous coronary intervention.

Hamon, Riddell; (Comment, Letter)

Targeted therapy for metastatic breast cancer.

Muss; (Comment, Editorial)

Eculizumab in paroxysmal nocturnal hemoglobinuria.

Kathula; (Comment, Letter)

Female predominance and transmission distortion in the long-QT syndrome.

Imboden, Swan, Denjoy, Van Langen, Latinen-Forsblom, Napolitano, Fressart, Breithardt, Berthet, Priori, Hainque, Wilde, Schulze-Bahr, Feingold, Guicheney; (Journal Article, Research Support, Non-U.S. Gov't)

Acute vulvovaginitis.

Shirley; (Comment, Letter)

Images in clinical medicine. Benign diffuse breast hyperplasia during pregnancy.

Pasrija, Sharma; (Journal Article)

Eculizumab in paroxysmal nocturnal hemoglobinuria.

Singh, Malani, Pabla; (Comment, Letter)

Deficiency of cartilage-associated protein in recessive lethal osteogenesis imperfecta.

Barnes, Chang, Morello, Cabral, Weis, Eyre, Leikin, Makareeva, Kuznetsova, Uveges, Ashok, Flor, Mulvihill, Wilson, Sundaram, Lee, Marini; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Images in clinical medicine. Adults with osteogenesis imperfecta.

Reeder, Orwoll; (Journal Article)

Echinocandins for candidemia.

Garcia-Vidal, Carratalà; (Comment, Letter)

Lapatinib plus capecitabine for HER2-positive advanced breast cancer.

Geyer, Forster, Lindquist, Chan, Romieu, Pienkowski, Jagiello-Gruszfeld, Crown, Chan, Kaufman, Skarlos, Campone, Davidson, Berger, Oliva, Rubin, Stein, Cameron; (Journal Article, Research Support, Non-U.S. Gov't)

Enoxaparin in elective percutaneous coronary intervention.

Schuler, Altenberger, Heigert; (Comment, Letter)

Effects of dietary nitrate on blood pressure in healthy volunteers.

Larsen, Ekblom, Sahlin, Lundberg, Weitzberg; (Letter, Research Support, Non-U.S. Gov't)

Enoxaparin in elective percutaneous coronary intervention.

Pasceri; (Comment, Letter)

Familial pathways to suicidal behavior--understanding and preventing suicide among adolescents.

Brent, Mann; (Journal Article)

Enoxaparin in elective percutaneous coronary intervention.

Bhala; (Comment, Letter)

Clinical practice. Monoclonal gammopathy of undetermined significance.

Bladé; (Journal Article, Research Support, Non-U.S. Gov't)

Enoxaparin in elective percutaneous coronary intervention.

Karthikeyan; (Comment, Letter)

The antidepressant quandary--considering suicide risk when treating adolescent depression.

Simon; (Journal Article)

Human Trypanosoma evansi infection linked to a lack of apolipoprotein L-I.

Vanhollebeke, Truc, Poelvoorde, Pays, Joshi, Katti, Jannin, Pays; (Journal Article, Research Support, Non-U.S. Gov't)

Eculizumab in paroxysmal nocturnal hemoglobinuria.

Takita, Matsumura, Kami; (Comment, Letter)

An intervention to decrease catheter-related bloodstream infections in the ICU.

Pronovost, Needham, Berenholtz, Sinopoli, Chu, Cosgrove, Sexton, Hyzy, Welsh, Roth, Bander, Kepros, Goeschel; (Journal Article, Research Support, U.S. Gov't, P.H.S.)

Team-based prevention of catheter-related infections.

Wenzel, Edmond; (Comment, Editorial)

J Natl Cancer Inst

Lancet

Medical response to the 2005 terrorist bombings in London.

Turégano-Fuentes, Pérez-Díaz; (Comment, Journal Article)

Dementia and white-matter demyelination in young patient with neurosyphilis.

Brinar, Habek; (Journal Article)

Mortality of HIV-infected patients in low-income countries.

Kadhiravan, Sharma; (Comment, Letter)

Estimation of potential global pandemic influenza mortality on the basis of vital registry data from the 1918-20 pandemic: a quantitative analysis.

Murray, Lopez, Chin, Feehan, Hill; (Journal Article, Research Support, N.I.H., Extramural)

Iain Chalmers: maverick master of medical evidence.

Watts; (News)

Prion reduction filters.

Turner; (Comment, Journal Article)

Lifeline: ken Arnold.

none; (Journal Article)

Lifeline: richard m berlin.

none; (Journal Article)

Paracetamol: are therapeutic doses entirely safe?

Jalan, Williams, Bernuau; (Journal Article)

Mortality of HIV-infected patients in low-income countries - Authors' response.

Brinkhof, Egger, Schechter, Dabis; (LETTER)

Reduction in critical mortality in urban mass casualty incidents: analysis of triage, surge, and resource use after the London bombings on July 7, 2005.

Aylwin, König, Brennan, Shirley, Davies, Walsh, Brohi; (Journal Article)

Essay: Composing a song to teach about dengue fever.

Chan; (Journal Article)

Essay: History of transplantation.

Calne; (Journal Article)

Health reform in Chile.

Letelier, Bedregal; (Journal Article)

Risk in drug trials.

Focosi; (Comment, Letter)

Safety and immunogenicity of H5N1 vaccine.

Authier, Gherardi; (Comment, Letter)

Profile: Sir Greg Winter-humaniser of antibodies.

Harding; (Journal Article)

Essay: your life in their hands.

Essex-Lopresti; (Journal Article)

Foreword: Fruits of originality.

The Lancet; (Editorial)

TGN1412 and The Lancet's solicitation of reports of phase I trials.

Chalmers; (Comment, Letter)

Essay: "With great power..." The relevance of science fiction to the practice and progress of medicine.

Pomidor, Pomidor; (Journal Article)

Payments for health care in India.

Devadasan, Van Damme; (Comment, Letter)

Poverty, death, and a future influenza pandemic.

Ferguson; (Comment, Journal Article)

Essay: Medical robotics-a bright future.

Davies; (Journal Article)

Reduction in infectivity of endogenous transmissible spongiform encephalopathies present in blood by adsorption to selective affinity resins.

Gregori, Gurgel, Lathrop, Edwardson, Lambert, Carbonell, Burton, Hammond, Rohwer; (Journal Article, Research Support, Non-U.S. Gov't)

Essay: noma.

Damme; (Journal Article)

Kofi Annan's positive legacy for health.

none; (Editorial)

Varicella in immunocompromised patients.

Vinzio, Lioure, Goichot; (Comment, Letter)

Alcohol abuse in the critically ill patient.

Moss, Burnham; (Journal Article, Research Support, N.I.H., Extramural)

Risk in drug trials.

Sugarman, Levine; (Comment, Letter)

Information alongside medicines.

Wilkinson; (News)

Essay: Monoclonal antibodies-designer medical missiles.

Stone; (Journal Article)

Reducing inequalities from injuries in Europe.

Sethi, Racioppi, Baumgarten, Bertollini; (Journal Article)

Essay: Evidence-based health-care architecture.

Ulrich; (Journal Article)

Lifeline: bernard devauchelle.

none; (Journal Article)

Personal Account: How IVF changed my life.

Birrittieri; (Journal Article)

Essay: Healing gardens-places for nature in health care.

Hartig, Marcus; (Journal Article)

Essay: Healing through art therapy in disaster settings.

Ahmed, Siddiqi; (Journal Article)

Richard Joseph Mulvaney.

Oransky; (Biography, Historical Article, Journal Article)

Essay: Hospital clowns-modern-day court jesters at work.

Spitzer; (Journal Article)

Essay: Development of children's creativity to foster peace.

Ishaq; (Journal Article)

Is Burkitt's lymphoma sexy enough?

Phillips; (Journal Article)

Profile: ray tallis.

Watts; (Journal Article)

Essay: Art created by psychiatric patients.

Lejsted, Nielsen; (Journal Article)

Feature: Issues on female genital mutilation/cutting-progress and parallels.

Morris; (Journal Article)

Personal Account: The magic of theatre.

Schutz, Bilbrough; (Journal Article)

Essay: The miracle boat.

Gobin; (Journal Article)

Risk in drug trials.

Ohresser, Olive, Vanhove, Watier; (Comment, Letter)

Poverty and user fees for public health care in low-income countries: lessons from Uganda and Cambodia.

Meessen, Van Damme, Tashobya, Tibouti; (Journal Article)

Essay: Newspaper coverage of global health in the UK.

Boseley; (Journal Article)

Haemoglobin concentrations in chronic kidney disease.

Steinbrook; (Journal Article)

Essay: Creativity-the healthy muse.

Rothenberg; (Journal Article)

Dengue: setting the global research agenda.

Kroeger, Nathan; (Journal Article)

Oklahoma, OK: emergency preparedness in the USA.

none; (Editorial)

Essay: What can the arts bring to medical training?

Willson; (Journal Article)

Varicella vaccine: local convenience or global equity?

Durrheim; (Comment, Letter)

Essay: Can we ensure health is within reach for everyone?

Elias; (Journal Article)

Essay: Writing and healing.

Jones; (Journal Article)

Essay: Wilderness medicine and creativity.

Freer; (Journal Article)

Essay: Theatre-a force for health promotion.

Mbizvo; (Journal Article)

Developing country trialists are key for malaria vaccine goals.

none; (Editorial)

Feature: Medical interventions-visual art meets medical technology.

Abbott; (Journal Article)

Interview: Chance favours the prepared mind.

Richardson; (Journal Article)

Risk in drug trials.

Barnes, Holbrook, Feild, Searls, Sanseau; (Comment, Letter)

Suboptimum use of FDA drug advisory committees.

Tapley, Lurie, Wolfe; (Letter)

Expert Rev Mol Diagn

Unraveling the genetics of atherosclerosis: implications for diagnosis and treatment.

Seo, Goldschmidt-Clermont; (Journal Article)

Molecular profiling of lung carcinoma: identifying clinically useful tumor markers for diagnosis and prognosis.

Dacic; (Journal Article)

Drug discovery without a molecular target: the road less traveled.

Ross-Macdonald; (Editorial)

Fluorescent proteins in drug development. 13-14 November 2006, La Jolla, California, USA.

Giuliano; (Journal Article)

Two new mutation 'hot-spots' identified in H5N1 viral strain.

none; (Journal Article)

Multiplexing molecular diagnostics and immunoassays using emerging microarray technologies.

Ling, Ricks, Lea; (Journal Article)

Preimplantation genetic diagnosis for monogenic diseases: overview and emerging issues.

Renwick, Ogilvie; (Journal Article)

HER2 testing: a review of detection methodologies and their clinical performance.

Laudadio, Quigley, Tubbs, Wolff; (Journal Article)

Arrayed identification of DNA signatures.

Käller, Lundeberg, Ahmadian; (Journal Article, Research Support, Non-U.S. Gov't)

Galactomannan antigen detection in the diagnosis of invasive aspergillosis.

Verdaguer, Walsh, Hope, Cortez; (Journal Article)

Fluorescence in situ hybridization: a multitarget approach in diagnosis and management of urothelial cancer.

Arentsen, de la Rosette, de Reijke, Langbein; (Journal Article)