Nature

Life: porridge would be just right for each universe.

Stewart; (Journal Article)

Research highlights.

none; (Journal Article)

A critical ligamentous mechanism in the evolution of avian flight.

Baier, Gatesy, Jenkins; (JOURNAL ARTICLE)

Oxygen content of transmembrane proteins over macroevolutionary time scales.

Acquisti, Kleffe, Collins; (JOURNAL ARTICLE)

A new gamma-ray burst classification scheme from GRB 060614.

Gehrels, Norris, Barthelmy, Granot, Kaneko, Kouveliotou, Markwardt, Mészáros, Nakar, Nousek, O'Brien, Page, Palmer, Parsons, Roming, Sakamoto, Sarazin, Schady, Stamatikos, Woosley; (Journal Article)

Termination of asymmetric cell division and differentiation of stomata.

Pillitteri, Sloan, Bogenschutz, Torii; (JOURNAL ARTICLE)

Gravity probe falters.

Brumfiel; (News)

An enigmatic long-lasting gamma-ray burst not accompanied by a bright supernova.

Della Valle, Chincarini, Panagia, Tagliaferri, Malesani, Testa, Fugazza, Campana, Covino, Mangano, Antonelli, D'Avanzo, Hurley, Mirabel, Pellizza, Piranomonte, Stella; (Journal Article, Research Support, Non-U.S. Gov't)

Transcription factor control of asymmetric cell divisions that establish the stomatal lineage.

Macalister, Ohashi-Ito, Bergmann; (JOURNAL ARTICLE)

Oceanography: creating the perfect wave.

Schrope; (News)

Days of Futures past.

none; (Editorial)

Physiology: freaks of nature?

Pearson; (News)

Mathematics: proof at a roll of the dice.

Chazelle; (News)

A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.

Niedernhofer, Garinis, Raams, Lalai, Robinson, Appeldoorn, Odijk, Oostendorp, Ahmad, van Leeuwen, Theil, Vermeulen, van der Horst, Meinecke, Kleijer, Vijg, Jaspers, Hoeijmakers; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Ageing: too fast by mistake.

Kirkwood; (Comment, News)

Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis.

Ridgway, Zhang, Wu, Stawicki, Liang, Chanthery, Kowalski, Watts, Callahan, Kasman, Singh, Chien, Tan, Hongo, de Sauvage, Plowman, Yan; (Journal Article)

Kyoto for commuters.

none; (Editorial)

Palaeontology: Embryonic identity crisis.

Donoghue; (JOURNAL ARTICLE)

A deep dynamo generating Mercury's magnetic field.

Christensen; (Journal Article)

Green activists enlist penguins to save the world.

McGoldrick, Marris; (News)

The ambiguity is the essence.

Lightman; (Journal Article)

Peer review and fraud.

none; (Editorial)

Biography of Crick aims to inspire a wider audience.

Ashburner, Bretscher, Lawrence; (Journal Article)

A novel explosive process is required for the gamma-ray burst GRB 060614.

Gal-Yam, Fox, Price, Ofek, Davis, Leonard, Soderberg, Schmidt, Lewis, Peterson, Kulkarni, Berger, Cenko, Sari, Sharon, Frail, Moon, Brown, Cucchiara, Harrison, Piran, Persson, McCarthy, Penprase, Chevalier, MacFadyen; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Evidence of giant sulphur bacteria in Neoproterozoic phosphorites.

Bailey, Joye, Kalanetra, Flood, Corsetti; (JOURNAL ARTICLE)

Correction.

none; (Journal Article)

Olfaction: underwater 'sniffing' by semi-aquatic mammals.

Catania; (Journal Article)

Better, faster--and easier to use.

none; (Journal Article)

Sidelines.

none; (Journal Article)

Human evolution: how Africa learned to love the cow.

Check; (News)

Categorization of behavioural sequences in the prefrontal cortex.

Shima, Isoda, Mushiake, Tanji; (JOURNAL ARTICLE)

Key collaboration.

none; (Journal Article)

Life: perhaps we should take the porridge theory with a pinch of salt.

Wigley; (Journal Article)

Abstractions.

none; (Journal Article)

Biomechanics: rubber bands reduce the cost of carrying loads.

Rome, Flynn, Yoo; (Journal Article)

The next pandemic.

Oxford; (Journal Article)

Fortnightly variations in the flow velocity of Rutford Ice Stream, West Antarctica.

Gudmundsson; (Journal Article, Research Support, Non-U.S. Gov't)

Physiology: obesity and gut flora.

Bajzer, Seeley; (Comment, News)

An obesity-associated gut microbiome with increased capacity for energy harvest.

Turnbaugh, Ley, Mahowald, Magrini, Mardis, Gordon; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Microbial ecology: human gut microbes associated with obesity.

Ley, Turnbaugh, Klein, Gordon; (Journal Article)

Evolutionary biology: Oxygen at life's boundaries.

Baudouin-Cornu, Thomas; (JOURNAL ARTICLE)

Climate credits.

none; (News)

The beginning of wisdom.

Taylor; (Journal Article)

Intrasexual competition and sexual selection in cooperative mammals.

Clutton-Brock, Hodge, Spong, Russell, Jordan, Bennett, Sharpe, Manser; (Journal Article, Research Support, Non-U.S. Gov't)

Hotdogs at the end of the world.

Crook; (Journal Article)

Nanobiotechnology: small talk.

Gewin; (Journal Article)

Shellfish view of omega-3 and sustainable fisheries.

Robson; (Journal Article)

News in brief.

none; (Journal Article)

Parthenogenesis in Komodo dragons.

Watts, Buley, Sanderson, Boardman, Ciofi, Gibson; (Journal Article)

Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue.

Saeij, Coller, Boyle, Jerome, White, Boothroyd; (JOURNAL ARTICLE)

Neurobiology: auditory fidelity.

Parsons; (News)

Animal experiments under fire for poor design.

Giles; (News)

Astrophysics: a burst of new ideas.

Zhang; (Comment, News)

Optics: a light touch.

Webb; (News)

Observation of the radiative decay mode of the free neutron.

Nico, Dewey, Gentile, Mumm, Thompson, Fisher, Kremsky, Wietfeldt, Chupp, Cooper, Beise, Kiriluk, Byrne, Coakley; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Making the paper: Timothy Clutton-Brock.

none; (Journal Article)

Measures for measures.

Lehmann, Jackson, Lautrup; (Journal Article)

Particle Physics: neutrons radiating decay.

Severijns; (Comment, News)

2006 Gallery: brilliant display.

Marris; (News)

Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis.

Noguera-Troise, Daly, Papadopoulos, Coetzee, Boland, Gale, Lin, Yancopoulos, Thurston; (Journal Article)

No supernovae associated with two long-duration gamma-ray bursts.

Fynbo, Watson, Thöne, Sollerman, Bloom, Davis, Hjorth, Jakobsson, Jřrgensen, Graham, Fruchter, Bersier, Kewley, Cassan, Cerón, Foley, Gorosabel, Hinse, Horne, Jensen, Klose, Kocevski, Marquette, Perley, Ramirez-Ruiz, Stritzinger, Vreeswijk, Wijers, Woller, Xu, Zub; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Science in culture.

Kemp; (Journal Article)

50 & 100 years ago.

none; (Journal Article)

NIH offers free access to wealth of disease data.

Russo; (News)


Science

2007 U.S. budget. NIH trims award size as spending crunch looms.

Mervis; (News)

Retraction.

Chang, Roth, Reyes, Pornillos, Chen, Chen; (Retraction of Publication)

A giant European dinosaur and a new sauropod clade.

Royo-Torres, Cobos, Alcalá; (Journal Article, Research Support, Non-U.S. Gov't)

Wildlife conservation. River dolphins down for the count, and perhaps out.

Guo; (News)

Aquaculture in offshore zones.

Goudey; (Comment, Letter)

Biochemistry. Proteins in a small world.

Yeates, Beeby; (Comment, Journal Article)

Imaging of Germinal Center Selection Events During Affinity Maturation.

Allen, Okada, Tang, Cyster; (JOURNAL ARTICLE)

Data storage. Is the terabit within reach?

Service; (News)

Structure of dual function iron regulatory protein 1 complexed with ferritin IRE-RNA.

Walden, Selezneva, Dupuy, Volbeda, Fontecilla-Camps, Theil, Volz; (Journal Article, Research Support, N.I.H., Extramural, Research Support, U.S. Gov't, Non-P.H.S.)

American Society for Cell Biology meeting. A gut germ goes AWOL.

Leslie; (News)

A "Silent" Polymorphism in the MDR1 Gene Changes Substrate Specificity.

Kimchi-Sarfaty, Oh, Kim, Sauna, Calcagno, Ambudkar, Gottesman; (JOURNAL ARTICLE)

Epidemiology. Influenza escapes immunity along neutral networks.

van Nimwegen; (Comment, Journal Article)

American Society for Cell Biology. Sprayed-on growth factors guide stem cells.

Leslie; (News)

Environment. Spain's prestige oil spill resurfaces.

Bosch; (News)

Breakthrough of the year. Areas to watch in 2007.

none; (News)

Scientific publishing. A scientist's nightmare: software problem leads to five retractions.

Miller; (Comment, News)

Evolution. The origin of insects.

Glenner, Thomsen, Hebsgaard, Sřrensen, Willerslev; (Journal Article, Research Support, Non-U.S. Gov't)

Ancient noncoding elements conserved in the human genome.

Venkatesh, Kirkness, Loh, Halpern, Lee, Johnson, Dandona, Viswanathan, Tay, Venter, Strausberg, Brenner; (Journal Article, Research Support, Non-U.S. Gov't)

Nonproliferation. Indo-U.S. nuclear pact in jeopardy.

Bagla; (News)

Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure.

Nackley, Shabalina, Tchivileva, Satterfield, Korchynskyi, Makarov, Maixner, Diatchenko; (Journal Article, Research Support, N.I.H., Extramural)

Relating three-dimensional structures to protein networks provides evolutionary insights.

Kim, Lu, Xia, Gerstein; (Journal Article, Research Support, Non-U.S. Gov't)

Archaeology. Researchers helpless as Bosnian pyramid bandwagon gathers pace.

Bohannon; (News)

Physics. Gaps and our understanding.

Millis; (Comment, Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Bruce Lahn profile. Links between brain genes, evolution, and cognition challenged.

Balter; (News)

Breakthrough of the year. The runners-up.

none; (News)

Scientific publishing. Don't pretty up that picture just yet.

Couzin; (News)

Breakthrough of the year. Scorecard 2006.

none; (News)

Characterizing a mammalian circannual pacemaker.

Lincoln, Clarke, Hut, Hazlerigg; (Journal Article, Research Support, Non-U.S. Gov't)

Earth science. A submarine volcano is caught in the act.

Chadwick; (Comment, Journal Article)

Epochal evolution shapes the phylodynamics of interpandemic influenza A (H3N2) in humans.

Koelle, Cobey, Grenfell, Pascual; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Bruce Lahn profile. Brain man makes waves with claims of recent human evolution.

Balter; (News)

Biochemistry. If the RNA fits, use it.

Rouault; (Comment, Journal Article)

Breakthrough of the year. Breakdown of the year: scientific fraud.

Couzin; (News)

U.S. ocean policy. Fisheries bill gives bigger role to science--but no money.

Stokstad; (News)

A gaseous metal disk around a white dwarf.

Gänsicke, Marsh, Southworth, Rebassa-Mansergas; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

SNPs, Silent But Not Invisible.

Komar; (JOURNAL ARTICLE)

Anticipatory reproduction and population growth in seed predators.

Boutin, Wauters, McAdam, Humphries, Tosi, Dhondt; (Journal Article, Research Support, Non-U.S. Gov't)

Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling.

Gavin, Hoebe, Duong, Ota, Martin, Beutler, Nemazee; (Journal Article, Research Support, N.I.H., Extramural)

Chemical and Spectroscopic Evidence for an FeV-Oxo Complex.

Tiago de Oliveira, Chanda, Banerjee, Shan, Mondal, Que Jr, Bominaar, Münck, Collins; (JOURNAL ARTICLE)

Lineages of acidophilic archaea revealed by community genomic analysis.

Baker, Tyson, Webb, Flanagan, Hugenholtz, Allen, Banfield; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

The heartbeat of the Oligocene climate system.

Pälike, Norris, Herrle, Wilson, Coxall, Lear, Shackleton, Tripati, Wade; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Immunology. Mouse studies question importance of toll-like receptors to vaccines.

Wickelgren; (Comment, News)

Nuclear Activity of MLA Immune Receptors Links Isolate-Specific and Basal Disease-Resistance Responses.

Shen, Saijo, Mauch, Biskup, Bieri, Keller, Seki, Ulker, Somssich, Schulze-Lefert; (JOURNAL ARTICLE)

Inquiry learning. Teaching scientific inquiry.

Hanauer, Jacobs-Sera, Pedulla, Cresawn, Hendrix, Hatfull; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Breakthrough of the year. The Poincaré conjecture--proved.

Mackenzie; (News)

Breakthrough of the year.

Kennedy; (Editorial)

Untemplated oligoadenylation promotes degradation of RISC-cleaved transcripts.

Ibrahim, Rohr, Jeong, Hesson, Cerutti; (Journal Article, Research Support, N.I.H., Extramural, Research Support, U.S. Gov't, Non-P.H.S.)


Nature Methods

Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization.

Scheres, Gao, Valle, Herman, Eggermont, Frank, Carazo; (JOURNAL ARTICLE)

Major signal increase in fluorescence microscopy through dark-state relaxation.

Donnert, Eggeling, Hell; (JOURNAL ARTICLE)

Accurate phylogenetic classification of variable-length DNA fragments.

McHardy, Martín, Tsirigos, Hugenholtz, Rigoutsos; (JOURNAL ARTICLE)

Recombineering in Mycobacterium tuberculosis.

van Kessel, Hatfull; (JOURNAL ARTICLE)

Sensitive protein detection via triple-binder proximity ligation assays.

Schallmeiner, Oksanen, Ericsson, Spĺngberg, Eriksson, Stenman, Pettersson, Landegren; (JOURNAL ARTICLE)

SILENCE: a new forward genetic technology.

Banks, Bradley; (JOURNAL ARTICLE)

Retrograde neuronal tracing with a deletion-mutant rabies virus.

Wickersham, Finke, Conzelmann, Callaway; (JOURNAL ARTICLE)

MRI-based localization of electrophysiological recording sites within the cerebral cortex at single-voxel accuracy.

Matsui, Koyano, Koyama, Nakahara, Takeda, Ohashi, Naya, Miyashita; (JOURNAL ARTICLE)


Nature Biotechnology

Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin.

Garcia-Rodriguez, Levy, Arndt, Forsyth, Razai, Lou, Geren, Stevens, Marks; (JOURNAL ARTICLE)


Nature Medicine

CD8(+) T-cell responses to different HIV proteins have discordant associations with viral load.

Kiepiela, Ngumbela, Thobakgale, Ramduth, Honeyborne, Moodley, Reddy, de Pierres, Mncube, Mkhwanazi, Bishop, van der Stok, Nair, Khan, Crawford, Payne, Leslie, Prado, Prendergast, Frater, McCarthy, Brander, Learn, Nickle, Rousseau, Coovadia, Mullins, Heckerman, Walker, Goulder; (JOURNAL ARTICLE)

Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.

Vilimas, Mascarenhas, Palomero, Mandal, Buonamici, Meng, Thompson, Spaulding, Macaroun, Alegre, Kee, Ferrando, Miele, Aifantis; (JOURNAL ARTICLE)


Nature Genetics

Integrative molecular concept modeling of prostate cancer progression.

Tomlins, Mehra, Rhodes, Cao, Wang, Dhanasekaran, Kalyana-Sundaram, Wei, Rubin, Pienta, Shah, Chinnaiyan; (JOURNAL ARTICLE)

Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders.

Durand, Betancur, Boeckers, Bockmann, Chaste, Fauchereau, Nygren, Rastam, Gillberg, Anckarsäter, Sponheim, Goubran-Botros, Delorme, Chabane, Mouren-Simeoni, de Mas, Bieth, Rogé, Héron, Burglen, Gillberg, Leboyer, Bourgeron; (JOURNAL ARTICLE)


Molecular Medicine


Proteomics

Protein labeling by iTRAQ: A new tool for quantitative mass spectrometry in proteome research.

Wiese, Reidegeld, Meyer, Warscheid; (JOURNAL ARTICLE)

Outer membrane proteome of Prevotella intermedia 17: Identification of thioredoxin and iron-repressible hemin uptake loci.

Yu, Anaya, Lewis; (JOURNAL ARTICLE)

Fe(3+) immobilized metal affinity chromatography with silica monolithic capillary column for phosphoproteome analysis.

Feng, Pan, Jiang, Xu, Zhou, Ye, Zou; (JOURNAL ARTICLE)


Nature Drug Discovery


BMC Bioinformatics

iHOPerator: User-scripting a personalized bioinformatics Web, starting with the iHOP website.

Good, Kawas, Kuo, Wilkinson; (JOURNAL ARTICLE)

PageMan: An interactive ontology tool to generate, display, and annotate overview graphs for profiling experiments.

Usadel, Nagel, Steinhauser, Gibon, Blasing, Redestig, Sreenivasulu, Krall, Hannah, Poree, Fernie, Stitt; (JOURNAL ARTICLE)

TaxMan: a taxonomic database manager.

Jones, Blaxter; (JOURNAL ARTICLE)

A method for estimation of elasticities in metabolic networks using steady state and dynamic metabolomics data and linlog kinetics.

Nikerel, van Winden, van Gulik, Heijnen; (JOURNAL ARTICLE)

Empirical study of supervised gene screening.

Ma; (JOURNAL ARTICLE)

Effect of various normalization methods on Applied Biosystems expression array system data.

Barbacioru, Wang, Canales, Sun, Keys, Chan, Poulter, Samaha; (JOURNAL ARTICLE)

Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments.

Sartor, Tomlinson, Wesselkamper, Sivaganesan, Leikauf, Medvedovic; (JOURNAL ARTICLE)

A minimally invasive multiple marker approach allows highly efficient detection of meningioma tumors.

Keller, Ludwig, Comtesse, Hildebrandt, Meese, Lenhof; (JOURNAL ARTICLE)


Bioinformatics

Robust prediction of consensus secondary structures using averaged base pairing probability matrices.

Kiryu, Kin, Asai; (JOURNAL ARTICLE)

Enrichment or depletion of a GO category within a class of genes: which test?

Rivals, Personnaz, Taing, Potier; (JOURNAL ARTICLE)

Clustering Threshold Gradient Descent Regularization: with applications to microarray studies.

Ma, Huang; (JOURNAL ARTICLE)

URec: a system for unrooted reconciliation.

Górecki; (JOURNAL ARTICLE)


Proc Natl Acad Sci U S A

Anisotropy of cell adhesive microenvironment governs cell internal organization and orientation of polarity.

Théry, Racine, Piel, Pépin, Dimitrov, Chen, Sibarita, Bornens; (JOURNAL ARTICLE)

Identification of the protein receptor binding site of botulinum neurotoxins B and G proves the double-receptor concept.

Rummel, Eichner, Weil, Karnath, Gutcaits, Mahrhold, Sandhoff, Proia, Acharya, Bigalke, Binz; (JOURNAL ARTICLE)

Introduced cryptic species of parasites exhibit different invasion pathways.

Miura, Torchin, Kuris, Hechinger, Chiba; (JOURNAL ARTICLE)

Sequential structure of neocortical spontaneous activity in vivo.

Luczak, Barthó, Marguet, Buzsáki, Harris; (JOURNAL ARTICLE)

Modulation of Leydig cell function by cyclic nucleotide phosphodiesterase 8A.

Vasta, Shimizu-Albergine, Beavo; (JOURNAL ARTICLE)

The power stroke of myosin VI and the basis of reverse directionality.

Bryant, Altman, Spudich; (JOURNAL ARTICLE)

Retraction for Nouspikel et al., A common mutational pattern in Cockayne syndrome patients from xeroderma pigmentosum group G: Implications for a second XPG function.

Snyder; (Journal Article)

Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK.

Galkin, Melnick, Kim, Hood, Li, Li, Xia, Steensma, Chopiuk, Jiang, Wan, Ding, Liu, Sun, Schultz, Gray, Warmuth; (JOURNAL ARTICLE)

Identification of quantitative trait loci affecting body composition in a mouse intercross.

Vitarius, Sehayek, Breslow; (JOURNAL ARTICLE)

Determination of solvent content in cavities in IL-1{beta} using experimentally phased electron density.

Quillin, Wingfield, Matthews; (JOURNAL ARTICLE)

Identification and characterization of COPIa- and COPIb-type vesicle classes associated with plant and algal Golgi.

Donohoe, Kang, Staehelin; (JOURNAL ARTICLE)

Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome.

de Jorge, Harris, Esparza-Gordillo, Carreras, Arranz, Garrido, López-Trascasa, Sánchez-Corral, Morgan, de Córdoba; (JOURNAL ARTICLE)

Synthetic small molecule furin inhibitors derived from 2,5-dideoxystreptamine.

Jiao, Cregar, Wang, Millis, Tang, O'malley, Johnson, Sareth, Larson, Thomas; (JOURNAL ARTICLE)

Computationally designed libraries of fluorescent proteins evaluated by preservation and diversity of function.

Treynor, Vizcarra, Nedelcu, Mayo; (JOURNAL ARTICLE)

Interstrain transfer of the large pathogenicity island (PAPI-1) of Pseudomonas aeruginosa.

Qiu, Gurkar, Lory; (JOURNAL ARTICLE)

S-adenosylhomocysteine hydrolase is localized at the front of chemotaxing cells, suggesting a role for transmethylation during migration.

Shu, Mahadeo, Liu, Liu, Parent, Korn; (JOURNAL ARTICLE)

Site-directed alkylation and the alternating access model for LacY.

Kaback, Dunten, Frillingos, Venkatesan, Kwaw, Zhang, Ermolova; (JOURNAL ARTICLE)

Role of protein frame and solvent for the redox properties of azurin from Pseudomonas aeruginosa.

Cascella, Magistrato, Tavernelli, Carloni, Rothlisberger; (JOURNAL ARTICLE)

How personal experience modulates the neural circuitry of memories of September 11.

Sharot, Martorella, Delgado, Phelps; (JOURNAL ARTICLE)

Single-stranded nucleic acid-induced helical self-assembly of alkynylplatinum(II) terpyridyl complexes.

Yu, Chan, Wong, Yam; (JOURNAL ARTICLE)

Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter.

Mahoney, Sammut, Xavier, Cunningham, Go, Brim, Stappenbeck, Miner, Swat; (JOURNAL ARTICLE)

cAMP activation of PKA defines an ancient signaling mechanism.

Das, Esposito, Abu-Abed, Anand, Taylor, Melacini; (JOURNAL ARTICLE)

IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo.

Carriere, Roussel, Ortega, Lacorre, Americh, Aguilar, Bouche, Girard; (JOURNAL ARTICLE)

Mechanism of allosteric regulation of transglutaminase 2 by GTP.

Begg, Carrington, Stokes, Matthews, Wouters, Husain, Lorand, Iismaa, Graham; (JOURNAL ARTICLE)

Structural transitions of complement component C3 and its activation products.

Nishida, Walz, Springer; (JOURNAL ARTICLE)

LIM-only protein, CRP2, switched on smooth muscle gene activity in adult cardiac myocytes.

Chang, Belaguli, Chang, Schwartz; (JOURNAL ARTICLE)

Adhesion and detachment mechanisms of sugar surfaces from the solid (glassy) to liquid (viscous) states.

Zhao, Zeng, Tian, Israelachvili; (JOURNAL ARTICLE)

NMDA-dependent facilitation of corticostriatal plasticity by the amygdala.

Popescu, Saghyan, Paré; (JOURNAL ARTICLE)

Mesodermal cell displacements during avian gastrulation are due to both individual cell-autonomous and convective tissue movements.

Zamir, Czirók, Cui, Little, Rongish; (JOURNAL ARTICLE)

Maternal serotonin is crucial for murine embryonic development.

Côté, Fligny, Bayard, Launay, Gershon, Mallet, Vodjdani; (JOURNAL ARTICLE)

Bidirectional signaling between calcium channels of skeletal muscle requires multiple direct and indirect interactions.

Sheridan, Takekura, Franzini-Armstrong, Beam, Allen, Perez; (JOURNAL ARTICLE)

Air pollution and climate change both reduce Indian rice harvests.

Cramer; (JOURNAL ARTICLE)

Amyloid precursor protein overexpression depresses excitatory transmission through both presynaptic and postsynaptic mechanisms.

Ting, Kelley, Lambert, Cook, Sullivan; (JOURNAL ARTICLE)

Natural selection for rash-forming genotypes of the varicella-zoster vaccine virus detected within immunized human hosts.

Quinlivan, Gershon, Al Bassam, Steinberg, Larussa, Nichols, Breuer; (JOURNAL ARTICLE)

Illuminating membrane fusion.

Rizo; (JOURNAL ARTICLE)

Positive affect increases the breadth of attentional selection.

Rowe, Hirsh, Anderson; (JOURNAL ARTICLE)

Mapping protein collapse with single-molecule fluorescence and kinetic synchrotron radiation circular dichroism spectroscopy.

Hoffmann, Kane, Nettels, E Hertzog, Baumgärtel, Lengefeld, Reichardt, Horsley, Seckler, Bakajin, Schuler; (JOURNAL ARTICLE)

Isolation and functional characterization of murine prostate stem cells.

Lawson, Xin, Lukacs, Cheng, Witte; (JOURNAL ARTICLE)

Ethanol prevents development of destructive arthritis.

Jonsson, Verdrengh, Brisslert, Lindblad, Bokarewa, Islander, Carlsten, Ohlsson, Nandakumar, Holmdahl, Tarkowski; (JOURNAL ARTICLE)

Profile of Edward L. Miles.

Downey; (JOURNAL ARTICLE)

Selection for Staphylococcus aureus small-colony variants due to growth in the presence of Pseudomonas aeruginosa.

Hoffman, Déziel, D'Argenio, Lépine, Emerson, McNamara, Gibson, Ramsey, Miller; (JOURNAL ARTICLE)

Order from disorder: Self-organization in mammalian hair patterning.

Wang, Badea, Nathans; (JOURNAL ARTICLE)

Nitric oxide release combined with nonsteroidal antiinflammatory activity prevents muscular dystrophy pathology and enhances stem cell therapy.

Brunelli, Sciorati, D'Antona, Innocenzi, Covarello, Galvez, Perrotta, Monopoli, Sanvito, Bottinelli, Ongini, Cossu, Clementi; (JOURNAL ARTICLE)

Divergence of reproductive phenology under climate warming.

Sherry, Zhou, Gu, Arnone, Schimel, Verburg, Wallace, Luo; (JOURNAL ARTICLE)

A PDZ domain recapitulates a unifying mechanism for protein folding.

Gianni, Geierhaas, Calosci, Jemth, Vuister, Travaglini-Allocatelli, Vendruscolo, Brunori; (JOURNAL ARTICLE)

Localized proton microcircuits at the biological membrane-water interface.

Brändén, Sandén, Brzezinski, Widengren; (JOURNAL ARTICLE)

Rae1 interaction with NuMA is required for bipolar spindle formation.

Wong, Blobel, Coutavas; (JOURNAL ARTICLE)

Nisin-induced changes in Bacillus morphology suggest a paradigm of antibiotic action.

Hyde, Parisot, McNichol, Bonev; (JOURNAL ARTICLE)

The 1',4'-iminopyrimidine tautomer of thiamin diphosphate is poised for catalysis in asymmetric active centers on enzymes.

Nemeria, Chakraborty, Baykal, Korotchkina, Patel, Jordan; (JOURNAL ARTICLE)

Phosphoinositide 3-kinase {gamma}/{delta} inhibition limits infarct size after myocardial ischemia/reperfusion injury.

Doukas, Wrasidlo, Noronha, Dneprovskaia, Fine, Weis, Hood, Demaria, Soll, Cheresh; (JOURNAL ARTICLE)

Filamin A (FLNA) is required for cell-cell contact in vascular development and cardiac morphogenesis.

Feng, Chen, Moskowitz, Mendonza, Vidali, Nakamura, Kwiatkowski, Walsh; (JOURNAL ARTICLE)

RecA-independent recombination is efficient but limited by exonucleases.

Dutra, Sutera, Lovett; (JOURNAL ARTICLE)

Topological dynamics of holins in programmed bacterial lysis.

Park, Struck, Deaton, Young; (JOURNAL ARTICLE)

Identification of long-range regulatory elements in the protocadherin-{alpha} gene cluster.

Ribich, Tasic, Maniatis; (JOURNAL ARTICLE)

Site-specific collapse dynamics guide the formation of the cytochrome c' four-helix bundle.

Kimura, Lee, Gray, Winkler; (JOURNAL ARTICLE)

Human Sco1 functional studies and pathological implications of the P174L mutant.

Banci, Bertini, Ciofi-Baffoni, Leontari, Martinelli, Palumaa, Sillard, Wang; (JOURNAL ARTICLE)

Mutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistance.

Nikolenko, Delviks-Frankenberry, Palmer, Maldarelli, Fivash, Coffin, Pathak; (JOURNAL ARTICLE)

The structural basis for the mutagenicity of O6-methyl-guanine lesions.

Warren, Forsberg, Beese; (JOURNAL ARTICLE)

The zinc-finger antiviral protein recruits the RNA processing exosome to degrade the target mRNA.

Guo, Ma, Sun, Gao; (JOURNAL ARTICLE)

Filamentation by Escherichia coli subverts innate defenses during urinary tract infection.

Justice, Hunstad, Seed, Hultgren; (JOURNAL ARTICLE)

A quantitative study of bioenergetics in skeletal muscle lacking carbonic anhydrase III using 31P magnetic resonance spectroscopy.

Liu, Walter, Pathare, Forster, Vandenborne; (JOURNAL ARTICLE)

Urban aerosols harbor diverse and dynamic bacterial populations.

Brodie, Desantis, Parker, Zubietta, Piceno, Andersen; (JOURNAL ARTICLE)

Varicella-zoster vaccine virus: Evolution in action.

Cohen; (JOURNAL ARTICLE)

Bcl10 plays a critical role in NF-{kappa}B activation induced by G protein-coupled receptors.

Wang, You, Lin, Xue, Morris, Zeng, Wen, Lin; (JOURNAL ARTICLE)

Reengineering CCA-adding enzymes to function as (U,G)- or dCdCdA-adding enzymes or poly(C,A) and poly(U,G) polymerases.

Cho, Verlinde, Weiner; (JOURNAL ARTICLE)

PSD-95 and PKC converge in regulating NMDA receptor trafficking and gating.

Lin, Jover-Mengual, Wong, Bennett, Zukin; (JOURNAL ARTICLE)

The first armadillo repeat is involved in the recognition and regulation of {beta}-catenin phosphorylation by protein kinase CK1.

Bustos, Ferrarese, Venerando, Marin, Allende, Pinna; (JOURNAL ARTICLE)

Processive enzyme mimic: Kinetics and thermodynamics of the threading and sliding process.

Coumans, Elemans, Nolte, Rowan; (JOURNAL ARTICLE)

Mechanism of tRNA-dependent editing in translational quality control.

Ling, Roy, Ibba; (JOURNAL ARTICLE)

Monoalkyl sulfates as alkylating agents in water, alkylsulfatase rate enhancements, and the "energy-rich" nature of sulfate half-esters.

Wolfenden, Yuan; (JOURNAL ARTICLE)

Evidence for a chemical-thermal structure at base of mantle from sharp lateral P-wave variations beneath Central America.

Sun, Song, Zheng, Helmberger; (JOURNAL ARTICLE)


N Engl J Med

Multiple biomarkers for the prediction of first major cardiovascular events and death.

Wang, Gona, Larson, Tofler, Levy, Newton-Cheh, Jacques, Rifai, Selhub, Robins, Benjamin, D'Agostino, Vasan; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Carbapenems for surgical prophylaxis?

Sexton; (Comment, Editorial)

Social anxiety disorder.

Schwaber; (Comment, Letter)

Images in clinical medicine. Disseminated paracoccidioidomycosis and coinfection with HIV.

Castro, Martinez; (Journal Article)

Overweight, obesity, and mortality.

Spitzer; (Comment, Letter)

The limitations of risk factors as prognostic tools.

Ware; (Comment, Journal Article)

Teaching surgical skills--changes in the wind.

Reznick, MacRae; (Journal Article)

Case records of the Massachusetts General Hospital. Case 39-2006. A 24-year-old woman with systemic lupus erythematosus, seizures, and right arm weakness.

Cha, Furie, Kay, Walensky, Mullins, Hedley-Whyte; (Clinical Conference, Journal Article)

Overweight, obesity, and mortality.

Appels, Vandenbroucke; (Comment, Letter)

Body-mass index and mortality in Korean men and women.

Oh; (Comment, Letter)

Overweight, obesity, and mortality.

Barzel; (Comment, Letter)

Ertapenem versus cefotetan prophylaxis in elective colorectal surgery.

Itani, Wilson, Awad, Jensen, Finn, Abramson; (Journal Article, Research Support, Non-U.S. Gov't)

Technical-skills training in the 21st century.

Aggarwal, Darzi; (Comment, Editorial)

Diagnosis of ventilator-associated pneumonia.

Kollef; (Comment, Editorial)

Cerebral aneurysms.

Finucane; (Comment, Letter)

Autoimmune pancreatitis.

Finkelberg, Sahani, Deshpande, Brugge; (Journal Article)

Reconstructing lives--a tale of two soldiers.

Okie; (Journal Article)

A randomized trial of diagnostic techniques for ventilator-associated pneumonia.

Heyland, Dodek, Muscedere, Day; (Journal Article, Research Support, Non-U.S. Gov't)

PET of brain amyloid and tau in mild cognitive impairment.

Small, Kepe, Ercoli, Siddarth, Bookheimer, Miller, Lavretsky, Burggren, Cole, Vinters, Thompson, Huang, Satyamurthy, Phelps, Barrio; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Use of statins and outcome of BCG treatment for bladder cancer.

Hoffmann, Roumegučre, Schulman, van Velthoven; (Letter)

Overweight, obesity, and mortality.

Hoofnagle; (Comment, Letter)

Cerebral aneurysms.

Whiteley, Salman; (Comment, Letter)

The persistence of memory.

Cookson, Hardy; (Journal Article)

Cerebral aneurysms.

Torres, Pirson, Wiebers; (Comment, Letter)

Images in clinical medicine. Multiple pulmonary bacterial abscesses.

Chen, Li; (Journal Article)

Cancer stem cells.

Wion, Berger; (Comment, Letter)


J Natl Cancer Inst

Stat bite: Breast cancer in young U.S. women.

none; (Journal Article)

5-year survival data not always a good measure of progress.

Schmidt; (News)

Lack of progress in teen and young adult cancers concerns researchers, prompts study.

Schmidt; (News)

E-prescribing first step to improved safety.

Finkelstein; (News)

Radiation-induced leukemia at doses relevant to radiation therapy: modeling mechanisms and estimating risks.

Shuryak, Sachs, Hlatky, Little, Hahnfeldt, Brenner; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation.

Phillips, McBride, Pajonk; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Dietary fat reduction and breast cancer outcome: interim efficacy results from the Women's Intervention Nutrition Study.

Chlebowski, Blackburn, Thomson, Nixon, Shapiro, Hoy, Goodman, Giuliano, Karanja, McAndrew, Hudis, Butler, Merkel, Kristal, Caan, Michaelson, Vinciguerra, Del Prete, Winkler, Hall, Simon, Winters, Elashoff; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Re: Frequency and cost of chemotherapy-related serious adverse effects in a population sample of women with breast cancer.

Russo, Autelitano, Bisanti; (Comment, Letter)

Statin drugs and risk of advanced prostate cancer.

Platz, Leitzmann, Visvanathan, Rimm, Stampfer, Willett, Giovannucci; (Journal Article, Research Support, N.I.H., Extramural)

Cancer stem cells and radiotherapy: new insights into tumor radioresistance.

Diehn, Clarke; (Comment, Editorial)

Effect of cromolyn on S100P interactions with RAGE and pancreatic cancer growth and invasion in mouse models.

Arumugam, Ramachandran, Logsdon; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Dietary fat and breast cancer: contributions from a survival trial.

Thiébaut, Schatzkin, Ballard-Barbash, Kipnis; (Comment, Editorial)

Cost-utility analysis of short- versus long-course palliative radiotherapy in patients with non-small-cell lung cancer.

van den Hout, Kramer, Noordijk, Leer; (Journal Article, Research Support, Non-U.S. Gov't)

The European Commission may network tissue banks to boost cancer research, promote cooperation.

Sinha; (News)

Re: Incidence of initial local therapy among men with lower-risk prostate cancer in the United States.

Vikram; (Comment, Letter)

Tumor complexity prompts caution about sequencing.

Beckman; (News)


Lancet

Maternal survival: more research is needed.

Belizán, Buekens, Althabe, Bergel; (Comment, Letter)

Art for women's health.

Merialdi, Requejo, Campana; (Journal Article)

A comparison of three highly active antiretroviral treatment strategies consisting of non-nucleoside reverse transcriptase inhibitors, protease inhibitors, or both in the presence of nucleoside reverse transcriptase inhibitors as initial therapy (CPCRA 058 FIRST Study): a long-term randomised trial.

MacArthur, Novak, Peng, Chen, Xiang, Hullsiek, Kozal, van den Berg-Wolf, Henely, Schmetter, Dehlinger; (Journal Article, Research Support, N.I.H., Extramural)

Reducing maternal mortality where rates are greatest.

Christian, Sommer, West; (Comment, Letter)

Oral misoprostol for postpartum haemorrhage.

Weeks; (Comment, Letter)

Strategies for stroke management.

none; (Editorial)

Out of the frying pan...

none; (Editorial)

New guidance on doctors' behaviour from the UK Prime Minister.

Caldwell; (Letter)

Epidemiology of antituberculosis drug resistance (the Global Project on Anti-tuberculosis Drug Resistance Surveillance): an updated analysis.

Aziz, Wright, Laszlo, De Muynck, Portaels, Van Deun, Wells, Nunn, Blanc, Raviglione; (Journal Article)

A cool case: hypothermia and adrenal failure.

Grossmann, Topliss; (Journal Article)

Pralidoxime for organophosphate poisoning.

Eyer, Buckley; (Comment, Journal Article)

Measuring maternal mortality.

Hill; (Comment, Letter)

Polish drug factory closed after treatment mix up.

Cienski; (News)

Strategies for reducing maternal mortality.

Jokhio, Winter, Cheng, Khan, MacArthur; (Comment, Letter)

Developmental neurotoxicity of industrial chemicals.

Grandjean, Landrigan; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Generalised anxiety disorder.

Tyrer, Baldwin; (Journal Article)

Initial strategy for antiretroviral-naive patients.

Abgrall; (Comment, Journal Article)

Dietary folate deficiency and bilateral retinal haemorrhages.

Hughes, Leach; (Journal Article)

DDT: a polluted debate in malaria control.

Schapira; (Journal Article)

Ilora Finlay. Interview.

none; (Interview)

September, 2006.

none; (JOURNAL ARTICLE)

The health of Europe's most marginalised populations.

Loewenberg; (News)

Reorganising research in the UK.

none; (Editorial)

Continuous pralidoxime infusion versus repeated bolus injection to treat organophosphorus pesticide poisoning: a randomised controlled trial.

Pawar, Bhoite, Pillay, Chavan, Malshikare, Garad; (Journal Article)

Strategies for reducing maternal mortality.

Fauveau; (Comment, Letter)

A new Director General for WHO--an opportunity for bold and inspirational leadership.

McCoy, Narayan, Baum, Sanders, Serag, Salvage, Rowson, Schrecker, Woodward, Labonte, Sengupta, Qizphe, Schuftan; (Journal Article)


Expert Rev Mol Diagn