Nature

The godmother protocols.

Whitney; (Journal Article)

CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast.

Tanaka, Umemori, Hirai, Muramatsu, Kamimura, Araki; (JOURNAL ARTICLE)

Animal research: caught in the middle.

Smith; (News)

Negligible glacial-interglacial variation in continental chemical weathering rates.

Foster, Vance; (Journal Article, Research Support, Non-U.S. Gov't)

High-level similarity of dentitions in carnivorans and rodents.

Evans, Wilson, Fortelius, Jernvall; (JOURNAL ARTICLE)

Top of the pops.

Turney; (JOURNAL ARTICLE)

Reducing the burden of childhood malaria in Africa: the role of improved.

Rafael, Taylor, Magill, Lim, Girosi, Allan; (Journal Article)

Animal research: a matter of life and death.

none; (News)

Protein arrays: (Almost) no assembly required.

Eisentein; (Journal Article)

Two chemosensory receptors together mediate carbon dioxide detection in Drosophila.

Jones, Cayirlioglu, Grunwald Kadow, Vosshall; (JOURNAL ARTICLE)

Animal research: Grey Matters.

Marris; (News)

Reducing the global burden of tuberculosis: the contribution of improved diagnostics.

Keeler, Perkins, Small, Hanson, Reed, Cunningham, Aledort, Hillborne, Rafael, Girosi, Dye; (Journal Article)

Conservation biology: unkind cuts for incense.

Moore; (News)

Patterning organic single-crystal transistor arrays.

Briseno, Mannsfeld, Ling, Liu, Tseng, Reese, Roberts, Yang, Wudl, Bao; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Research highlights.

none; (JOURNAL ARTICLE)

Real-space solution to the problem of full disclosure.

Rupp; (Letter)

Snapshot: 'so far, so good' for shuttle.

Hopkin; (News)

Stem-cell techique 'contrary to public order'.

Abbott; (News)

Gut hormones and the regulation of energy homeostasis.

Murphy, Bloom; (Journal Article, Research Support, Non-U.S. Gov't)

Key collaboration.

none; (JOURNAL ARTICLE)

Animal research: primates in the frame.

Cyranoski; (News)

Dynamical evolution of ecosystems.

Azaele, Pigolotti, Banavar, Maritan; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Condensed-matter physics: up the magnetic pressure.

Fisher, Pickett; (Comment, News)

In brief.

none; (JOURNAL ARTICLE)

Geochemistry: biosignatures and abiotic constraints on early life.

Lollar, McCollom; (Comment, Journal Article)

Closing the deal.

Hoag; (Journal Article)

Market watch.

Macilwain; (Journal Article)

A Mesozoic gliding mammal from northeastern China.

Meng, Hu, Wang, Wang, Li; (Journal Article, Research Support, Non-U.S. Gov't)

A bench to call your own.

Baker; (Journal Article)

Inhibition of cytohesins by SecinH3 leads to hepatic insulin resistance.

Hafner, Schmitz, Grüne, Srivatsan, Paul, Kolanus, Quast, Kremmer, Bauer, Famulok; (Journal Article, Research Support, Non-U.S. Gov't)

Essential role for collectrin in renal amino acid transport.

Danilczyk, Sarao, Remy, Benabbas, Stange, Richter, Arya, Pospisilik, Singer, Camargo, Makrides, Ramadan, Verrey, Wagner, Penninger; (JOURNAL ARTICLE)

Animal research: mighty mouse.

Qiu; (News)

Geochemistry: Biosignatures and abiotic constraints on early life (Reply).

Ueno, Yamada, Yoshida, Maruyama, Isozaki; (JOURNAL ARTICLE)

Protein arrays: Table of suppliers.

none; (JOURNAL ARTICLE)

Swoop and swerve.

Moffatt; (JOURNAL ARTICLE)

Minority spin condensate in the spin-polarized superfluid 3He A1 phase.

Yamaguchi, Kobayashi, Ishimoto, Kojima; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Global health diagnostics.

Hay Burgess, Wasserman, Dahl; (Journal Article)

Saving time.

Jardine; (JOURNAL ARTICLE)

Australia lifts ban on cloning.

Cyranoski; (News)

Agency set up to tackle bioterror.

Wadman; (News)

Inflammation and metabolic disorders.

Hotamisligil; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

The view from Russia.

Gelfand; (Journal Article)

Calmer waters ahead.

none; (Editorial)

2006 wrapped up.

Purton; (JOURNAL ARTICLE)

An open debate.

none; (Editorial)

Reducing the global burden of acute lower respiratory infections in children: the contribution of new diagnostics.

Lim, Steinhoff, Girosi, Holtzman, Campbell, Boer, Black, Mulholland; (Journal Article)

Evolutionary genetics: Evolution of mate choice in the wild (Reply).

Qvarnström, Brommer, Gustafsson; (JOURNAL ARTICLE)

Cultural differences reduce Japanese researchers' visibility on the Web.

Ito, Wiesel; (Letter)

Protein arrays: losing the label.

Eisentein; (Journal Article)

Evolutionary genetics: evolution of mate choice in the wild.

Postma, Griffith, Brooks; (Comment, Journal Article)

Structural biology: Dangerous liaisons on neurons.

Schiavo; (JOURNAL ARTICLE)

Changes at the helm fuel Salk expansion plans.

Dalton; (News)

Semiconductor electronics: organic crystals at large.

Heremans; (Comment, News)

Protein arrays: growing pains.

Eisenstein; (Journal Article)

An SCN9A channelopathy causes congenital inability to experience pain.

Cox, Reimann, Nicholas, Thornton, Roberts, Springell, Karbani, Jafri, Mannan, Raashid, Al-Gazali, Hamamy, Valente, Gorman, Williams, McHale, Wood, Gribble, Woods; (Journal Article, Research Support, Non-U.S. Gov't)

Developing and interpreting models to improve diagnostics in developing countries.

Girosi, Olmsted, Keeler, Hay Burgess, Lim, Aledort, Rafael, Ricci, Boer, Hilborne, Derose, Shea, Beighley, Dahl, Wasserman; (Journal Article)

The cytohesin Steppke is essential for insulin signalling in Drosophila.

Fuss, Becker, Zinke, Hoch; (Journal Article, Research Support, Non-U.S. Gov't)

A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family.

Bocquet, Prado de Carvalho, Cartaud, Neyton, Le Poupon, Taly, Grutter, Changeux, Corringer; (JOURNAL ARTICLE)

Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity.

Jin, Rummel, Binz, Brunger; (JOURNAL ARTICLE)

Sidelines.

none; (JOURNAL ARTICLE)

When good cholesterol turns bad.

Pearson; (News)

Adipocytes as regulators of energy balance and glucose homeostasis.

Rosen, Spiegelman; (Journal Article)

Requirements for high impact diagnostics in the developing world.

Urdea, Penny, Olmsted, Giovanni, Kaspar, Shepherd, Wilson, Dahl, Buchsbaum, Moeller, Hay Burgess; (Journal Article)

A stomatin-domain protein essential for touch sensation in the mouse.

Wetzel, Hu, Riethmacher, Benckendorff, Harder, Eilers, Moshourab, Kozlenkov, Labuz, Caspani, Erdmann, Machelska, Heppenstall, Lewin; (JOURNAL ARTICLE)

Structural basis of cell surface receptor recognition by botulinum neurotoxin B.

Chai, Arndt, Dong, Tepp, Johnson, Chapman, Stevens; (JOURNAL ARTICLE)

Christmas Reading.

none; (JOURNAL ARTICLE)

Mechanisms linking obesity to insulin resistance and type 2 diabetes.

Kahn, Hull, Utzschneider; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast.

Zegerman, Diffley; (JOURNAL ARTICLE)

Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1.

Ribeil, Zermati, Vandekerckhove, Cathelin, Kersual, Dussiot, Coulon, Cruz Moura, Zeuner, Kirkegaard-Sřrensen, Varet, Solary, Garrido, Hermine; (JOURNAL ARTICLE)

Making the paper: Jin Meng. How a fossil helped to redraw the mammalian family tree.

none; (Journal Article)

Obesity and diabetes.

Nath, Heemels, Anson; (Journal Article, Research Support, Non-U.S. Gov't)

Molecular epidemiology: HIV-1 and HCV sequences from Libyan outbreak.

de Oliveira, Pybus, Rambaut, Salemi, Cassol, Ciccozzi, Rezza, Gattinara, D'Arrigo, Amicosante, Perrin, Colizzi, Perno; (Journal Article)

Reducing the burden of sexually transmitted infections in resource-limited settings: the role of improved diagnostics.

Aledort, Ronald, Rafael, Girosi, Vickerman, Le Blancq, Landay, Holmes, Ridzon, Hellmann, Shea, Peeling; (Journal Article)

Abstractions.

none; (JOURNAL ARTICLE)

MARSIS radar sounder evidence of buried basins in the northern lowlands of Mars.

Watters, Leuschen, Plaut, Picardi, Safaeinili, Clifford, Farrell, Ivanov, Phillips, Stofan; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Martian gullies turn tide in hunt for life.

Sanderson; (News)

Leukaemia: niche retreats for stem cells.

Williams, Cancelas; (News)

Reducing stunting among children: the potential contribution of diagnostics.

Ricci, Girosi, Tarr, Lim, Mason, Miller, Hughes, von Seidlein, Agosti, Guerrant; (Journal Article)

A vision of life after Blair.

Giles; (News)

A microworld in Triassic amber.

Schmidt, Ragazzi, Coppellotti, Roghi; (Journal Article)

50 & 100 Years Ago.

none; (JOURNAL ARTICLE)

News in brief.

none; (JOURNAL ARTICLE)

Slip on 'weak' faults by the rotation of regional stress in the fracture damage zone.

Faulkner, Mitchell, Healy, Heap; (Journal Article, Research Support, Non-U.S. Gov't)

Sirtuins as potential targets for metabolic syndrome.

Guarente; (Journal Article, Research Support, N.I.H., Extramural)

Reducing the burden of HIV/AIDS in infants: the contribution of improved diagnostics.

Aledort, Ronald, Le Blancq, Ridzon, Landay, Rafael, Shea, Safrit, Peeling, Hellmann, Mwaba, Holmes, Wilfert; (Journal Article)

Abdominal obesity and metabolic syndrome.

Després, Lemieux; (Journal Article, Research Support, Non-U.S. Gov't)

Protein arrays: an apt solution?

Eisentein; (Journal Article)

Characterization of a carbohydrate transporter from symbiotic glomeromycotan fungi.

Schüssler, Martin, Cohen, Fitz, Wipf; (Journal Article, Research Support, Non-U.S. Gov't)

Correction.

none; (JOURNAL ARTICLE)

Diabetes: kicking off the insulin cascade.

Jackson; (Comment, News)

Optics: momentum in an uncertain light.

Leonhardt; (News)

Mechanisms linking obesity with cardiovascular disease.

Van Gaal, Mertens, De Block; (Journal Article)

The elephant in the room.

none; (Editorial)

Neurobiology: a channel sets the gain on pain.

Waxman; (Comment, News)

Aerial ambition.

none; (Journal Article)


Science

Geophysics. Ancient cataclysm marred the Med.

Pasotti; (News)

International affairs. Iranians fume over a closed SESAME.

Bhattacharjee; (News)

Enzyme-free nucleic acid logic circuits.

Seelig, Soloveichik, Zhang, Winfree; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Responding to amphibian loss.

Pounds, Carnaval, Puschendorf, Haddad, Masters; (Comment, Letter)

A brown dwarf mass donor in an accreting binary.

Littlefair, Dhillon, Marsh, Gänsicke, Southworth, Watson; (Journal Article, Research Support, Non-U.S. Gov't)

An Inward-Facing Conformation of a Putative Metal-Chelate-Type ABC Transporter.

Pinkett, Lee, Lum, Locher, Rees; (JOURNAL ARTICLE)

Archaeology. A hunter's paradise.

Curry; (News)

Vitaly Ginzburg profile. After a lifetime in Russian science, concern for the future.

Macwilliams; (News)

Scientific misconduct. Online sleuths challenge Cell paper.

Xin; (News)

Histocompatible Embryonic Stem Cells by Parthenogenesis.

Kim, Lerou, Yabuuchi, Lengerke, Ng, West, Kirby, Daly, Daley; (JOURNAL ARTICLE)

U-Pb isotopic age of the StW 573 hominid from Sterkfontein, South Africa.

Walker, Cliff, Latham; (Journal Article, Research Support, Non-U.S. Gov't)

Secondary siRNAs Result from Unprimed RNA Synthesis and Form a Distinct Class.

Sijen, Steiner, Thijssen, Plasterk; (JOURNAL ARTICLE)

Nitrogen fixation at 92 degrees C by a hydrothermal vent archaeon.

Mehta, Baross; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

GE Prize-winning essay. 2006 Grand Prize winner.

none; (Biography, Journal Article)

ENSO as an integrating concept in earth science.

McPhaden, Zebiak, Glantz; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Whence comets?

A'Hearn; (Journal Article)

Late-Neoproterozoic Deep-Ocean Oxygenation and the Rise of Animal Life.

Canfield, Poulton, Narbonne; (JOURNAL ARTICLE)

NASA returns rocks from a comet.

Burnett; (Journal Article)

Mineralogy and petrology of comet 81P/Wild 2 nucleus samples.

Zolensky, Zega, Yano, Wirick, Westphal, Weisberg, Weber, Warren, Velbel, Tsuchiyama, Tsou, Toppani, Tomioka, Tomeoka, Teslich, Taheri, Susini, Stroud, Stephan, Stadermann, Snead, Simon, Simionovici, See, Robert, Rietmeijer, Rao, Perronnet, Papanastassiou, Okudaira, Ohsumi, Ohnishi, Nakamura-Messenger, Nakamura, Mostefaoui, Mikouchi, Meibom, Matrajt, Marcus, Leroux, Lemelle, Le, Lanzirotti, Langenhorst, Krot, Keller, Kearsley, Joswiak, Jacob, Ishii, Harvey, Hagiya, Grossman, Grossman, Graham, Gounelle, Gillet, Genge, Flynn, Ferroir, Fallon, Ebel, Dai, Cordier, Clark, Chi, Butterworth, Brownlee, Bridges, Brennan, Brearley, Bradley, Bleuet, Bland, Bastien; (Journal Article)

Archaeology. Stone Age world beneath the Baltic Sea.

Curry; (News)

Biomass, size, and trophic status of top predators in the Pacific Ocean.

Sibert, Hampton, Kleiber, Maunder; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Five rules for the evolution of cooperation.

Nowak; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

The cost of access to HIV treatment.

Galatowitsch, Siegfried; (Comment, Letter)

GE Prize-winning essay. The emergence of cells during the origin of life.

Chen; (Journal Article)

Nuclear physics. Japan gets head start in race to build exotic isotope accelerators.

Normille, Cho; (News)

Astronomy. France to launch first exoplanet hunter.

Hellemans; (News)

Introduction to special issue. Look into the seeds of time.

Baker; (Journal Article)

Polymorphic secreted kinases are key virulence factors in toxoplasmosis.

Saeij, Boyle, Coller, Taylor, Sibley, Brooke-Powell, Ajioka, Boothroyd; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Astronomy. A ghostly star revealed in silhouette.

Maxted; (Comment, Journal Article)

Photoconductive coaxial nanotubes of molecularly connected electron donor and acceptor layers.

Yamamoto, Fukushima, Suna, Ishii, Saeki, Seki, Tagawa, Taniguchi, Kawai, Aida; (Journal Article)

Cell biology. Purinergic chemotaxis.

Linden; (Comment, Journal Article)

Comment on "Early domesticated fig in the Jordan Valley".

Lev-Yadun, Ne'eman, Abbo, Flaishman; (Comment, Journal Article)

Antibody Class Switching Mediated by Yeast Endonuclease-Generated DNA Breaks.

Zarrin, Del Vecchio, Tseng, Gleason, Zarin, Tian, Alt; (JOURNAL ARTICLE)

Greater disruption due to failure of inhibitory control on an ambiguous distractor.

Tsushima, Sasaki, Watanabe; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Isotopic compositions of cometary matter returned by Stardust.

McKeegan, Aléon, Bradley, Brownlee, Busemann, Butterworth, Chaussidon, Fallon, Floss, Gilmour, Gounelle, Graham, Guan, Heck, Hoppe, Hutcheon, Huth, Ishii, Ito, Jacobsen, Kearsley, Leshin, Liu, Lyon, Marhas, Marty, Matrajt, Meibom, Messenger, Mostefaoui, Mukhopadhyay, Nakamura-Messenger, Nittler, Palma, Pepin, Papanastassiou, Robert, Schlutter, Snead, Stadermann, Stroud, Tsou, Westphal, Young, Ziegler, Zimmermann, Zinner; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Impact features on Stardust: implications for comet 81P/Wild 2 dust.

Hörz, Bastien, Borg, Bradley, Bridges, Brownlee, Burchell, Chi, Cintala, Dai, Djouadi, Dominguez, Economou, Fairey, Floss, Franchi, Graham, Green, Heck, Hoppe, Huth, Ishii, Kearsley, Kissel, Leitner, Leroux, Marhas, Messenger, Schwandt, See, Snead, Stadermann, Stephan, Stroud, Teslich, Trigo-Rodríguez, Tuzzolino, Troadec, Tsou, Warren, Westphal, Wozniakiewicz, Wright, Zinner; (Journal Article)

Seismology. Do early tremors give sneak preview of quake's power?

Hellemans; (News)

Astronomy. Big bang points to stellar mix-up.

Podsiadlowski, Justham; (Comment, Journal Article)

Planetary science. A dry view of Enceladus puts a damper on chances for life there.

Kerr; (Comment, News)

Astronomy. Heavy elements in stars.

Boothroyd; (Comment, Journal Article)

Cost-benefit analysis of the RFA.

Dovichi, Soper; (Letter)

Organic Glasses with Exceptional Thermodynamic and Kinetic Stability.

Swallen, Kearns, Mapes, Kim, McMahon, Ediger, Wu, Yu, Satija; (JOURNAL ARTICLE)

Operation of a DNA robot arm inserted into a 2D DNA crystalline substrate.

Ding, Seeman; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

A positive feedback loop promotes transcription surge that jump-starts Salmonella virulence circuit.

Shin, Lee, Huang, Groisman; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Chemistry. Generating a photocurrent on the nanometer scale.

Wurthner; (Comment, Journal Article)

Present-day impact cratering rate and contemporary gully activity on Mars.

Malin, Edgett, Posiolova, McColley, Dobrea; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Taking the pulse of the oceans.

Alverson, Baker; (Editorial)

Climate change hearings and policy issues.

Meyer; (Letter)

Antibodies Get a Break.

Chaudhuri, Jasin; (JOURNAL ARTICLE)

Quantum spin Hall effect and topological phase transition in HgTe quantum wells.

Bernevig, Hughes, Zhang; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Nuclear weapons. U.S. study finds slower breakdown of plutonium in stockpiled weapons.

Kintisch; (News)

U.S. research spending. Congress endorses bigger NIH budget, Director's Fund.

Mervis; (News)

Neuroscience. The impact of invisible stimuli.

Stoerig; (Comment, Journal Article)

Amphiregulin, a TH2 cytokine enhancing resistance to nematodes.

Zaiss, Yang, Shah, Kobie, Urban, Mosmann; (Journal Article, Research Support, N.I.H., Extramural)

Comet 81P/Wild 2 under a microscope.

Brownlee, Tsou, Aléon, Alexander, Araki, Bajt, Baratta, Bastien, Bland, Bleuet, Borg, Bradley, Brearley, Brenker, Brennan, Bridges, Browning, Brucato, Bullock, Burchell, Busemann, Butterworth, Chaussidon, Cheuvront, Chi, Cintala, Clark, Clemett, Cody, Colangeli, Cooper, Cordier, Daghlian, Dai, D'Hendecourt, Djouadi, Dominguez, Duxbury, Dworkin, Ebel, Economou, Fakra, Fairey, Fallon, Ferrini, Ferroir, Fleckenstein, Floss, Flynn, Franchi, Fries, Gainsforth, Gallien, Genge, Gilles, Gillet, Gilmour, Glavin, Gounelle, Grady, Graham, Grant, Green, Grossemy, Grossman, Grossman, Guan, Hagiya, Harvey, Heck, Herzog, Hoppe, Hörz, Huth, Hutcheon, Ignatyev, Ishii, Ito, Jacob, Jacobsen, Jacobsen, Jones, Joswiak, Jurewicz, Kearsley, Keller, Khodja, Kilcoyne, Kissel, Krot, Langenhorst, Lanzirotti, Le, Leshin, Leitner, Lemelle, Leroux, Liu, Luening, Lyon, Macpherson, Marcus, Marhas, Marty, Matrajt, McKeegan, Meibom, Mennella, Messenger, Messenger, Mikouchi, Mostefaoui, Nakamura, Nakano, Newville, Nittler, Ohnishi, Ohsumi, Okudaira, Papanastassiou, Palma, Palumbo, Pepin, Perkins, Perronnet, Pianetta, Rao, Rietmeijer, Robert, Rost, Rotundi, Ryan, Sandford, Schwandt, See, Schlutter, Sheffield-Parker, Simionovici, Simon, Sitnitsky, Snead, Spencer, Stadermann, Steele, Stephan, Stroud, Susini, Sutton, Suzuki, Taheri, Taylor, Teslich, Tomeoka, Tomioka, Toppani, Trigo-Rodríguez, Troadec, Tsuchiyama, Tuzzolino, Tyliszczak, Uesugi, Velbel, Vellenga, Vicenzi, Vincze, Warren, Weber, Weisberg, Westphal, Wirick, Wooden, Wopenka, Wozniakiewicz, Wright, Yabuta, Yano, Young, Zare, Zega, Ziegler, Zimmerman, Zinner, Zolensky; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Show us the money.

Kennedy; (Editorial)

Elemental compositions of comet 81P/Wild 2 samples collected by Stardust.

Flynn, Bleuet, Borg, Bradley, Brenker, Brennan, Bridges, Brownlee, Bullock, Burghammer, Clark, Dai, Daghlian, Djouadi, Fakra, Ferroir, Floss, Franchi, Gainsforth, Gallien, Gillet, Grant, Graham, Green, Grossemy, Heck, Herzog, Hoppe, Hörz, Huth, Ignatyev, Ishii, Janssens, Joswiak, Kearsley, Khodja, Lanzirotti, Leitner, Lemelle, Leroux, Luening, Macpherson, Marhas, Marcus, Matrajt, Nakamura, Nakamura-Messenger, Nakano, Newville, Papanastassiou, Pianetta, Rao, Riekel, Rietmeijer, Rost, Schwandt, See, Sheffield-Parker, Simionovici, Sitnitsky, Snead, Stadermann, Stephan, Stroud, Susini, Suzuki, Sutton, Taylor, Teslich, Troadec, Tsou, Tsuchiyama, Uesugi, Vekemans, Vicenzi, Vincze, Westphal, Wozniakiewicz, Zinner, Zolensky; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Heterogeneous three-dimensional electronics by use of printed semiconductor nanomaterials.

Ahn, Kim, Lee, Jeon, Kang, Sun, Nuzzo, Rogers; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Infrared spectroscopy of comet 81P/Wild 2 samples returned by Stardust.

Keller, Bajt, Baratta, Borg, Bradley, Brownlee, Busemann, Brucato, Burchell, Colangeli, d'Hendecourt, Djouadi, Ferrini, Flynn, Franchi, Fries, Grady, Graham, Grossemy, Kearsley, Matrajt, Nakamura-Messenger, Mennella, Nittler, Palumbo, Stadermann, Tsou, Rotundi, Sandford, Snead, Steele, Wooden, Zolensky; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Atmosphere. An ancient carbon mystery.

Pagani, Caldeira, Archer, Zachos; (Journal Article)

Ecology. Tracking Ebola's deadly march among wild apes.

Vogel; (Comment, News)

Ultralow Thermal Conductivity in Disordered, Layered WSe2 Crystals.

Chiritescu, Cahill, Nguyen, Johnson, Bodapati, Keblinski, Zschack; (JOURNAL ARTICLE)

Neuroscience. Getting a read on Rett syndrome.

Miller; (News)

Honey bees and humans: shared innovation.

Lightfoot; (Comment, Letter)

Epidemiology. Ensuring safe drinking water in Bangladesh.

Ahmed, Ahuja, Alauddin, Hug, Lloyd, Pfaff, Pichler, Saltikov, Stute, van Geen; (Journal Article)

Carbon-negative biofuels from low-input high-diversity grassland biomass.

Tilman, Hill, Lehman; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Neuroscience. Matters of size.

Kopec, Malinow; (Journal Article)

Engineering yeast transcription machinery for improved ethanol tolerance and production.

Alper, Moxley, Nevoigt, Fink, Stephanopoulos; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

The mtDNA legacy of the Levantine early Upper Palaeolithic in Africa.

Olivieri, Achilli, Pala, Battaglia, Fornarino, Al-Zahery, Scozzari, Cruciani, Behar, Dugoujon, Coudray, Santachiara-Benerecetti, Semino, Bandelt, Torroni; (Journal Article, Research Support, Non-U.S. Gov't)

Maternal oxytocin triggers a transient inhibitory switch in GABA signaling in the fetal brain during delivery.

Tyzio, Cossart, Khalilov, Minlebaev, Hübner, Represa, Ben-Ari, Khazipov; (Journal Article, Research Support, Non-U.S. Gov't)

Planetary science. Mars Orbiter's swan song: the red planet is a-changin'.

Kerr; (Comment, News)

U.S. research spending. Scientists feel the pain as 2007 budget outlook grows dark.

Mervis; (News)

Dual infection with HIV and malaria fuels the spread of both diseases in sub-Saharan Africa.

Abu-Raddad, Patnaik, Kublin; (Journal Article, Research Support, N.I.H., Extramural)

Regulatory policy. EPA draws fire over air-review revisions.

Stokstad; (News)

Evolution. The puzzle of human sociality.

Boyd; (Comment, Journal Article)

Deciding who should get the flu vaccine.

Holmberg; (Comment, Letter)

Human evolution. There's more than one way to have your milk and drink it, too.

Gibbons; (News)

Ebola outbreak killed 5000 gorillas.

Bermejo, Rodríguez-Teijeiro, Illera, Barroso, Vilŕ, Walsh; (Journal Article, Research Support, Non-U.S. Gov't)

Optogenetics. Shining new light on neural circuits.

Miller; (News)

Synthesis-mediated release of a small RNA inhibitor of RNA polymerase.

Wassarman, Saecker; (Journal Article, Research Support, N.I.H., Extramural)

Research facilities. Neurobiology on the farm.

Bhattacharjee; (News)

Physics. Microwave cooling of an artificial atom.

Chiorescu; (Comment, Journal Article)

Organics captured from comet 81P/Wild 2 by the Stardust spacecraft.

Sandford, Aléon, Alexander, Araki, Bajt, Baratta, Borg, Bradley, Brownlee, Brucato, Burchell, Busemann, Butterworth, Clemett, Cody, Colangeli, Cooper, D'Hendecourt, Djouadi, Dworkin, Ferrini, Fleckenstein, Flynn, Franchi, Fries, Gilles, Glavin, Gounelle, Grossemy, Jacobsen, Keller, Kilcoyne, Leitner, Matrajt, Meibom, Mennella, Mostefaoui, Nittler, Palumbo, Papanastassiou, Robert, Rotundi, Snead, Spencer, Stadermann, Steele, Stephan, Tsou, Tyliszczak, Westphal, Wirick, Wopenka, Yabuta, Zare, Zolensky; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Arms control. Little progress at bioweapons talks.

Enserink; (News)

Nannoplankton extinction and origination across the Paleocene-Eocene Thermal Maximum.

Gibbs, Bown, Sessa, Bralower, Wilson; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors.

Chen, Corriden, Inoue, Yip, Hashiguchi, Zinkernagel, Nizet, Insel, Junger; (Journal Article, Research Support, N.I.H., Extramural)

European research. Unprecedented budget increase draws faint praise.

Enserink; (News)

Physics. A new spin on the insulating state.

Kane, Mele; (Comment, Journal Article)

Microwave-induced cooling of a superconducting qubit.

Valenzuela, Oliver, Berns, Berggren, Levitov, Orlando; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

A clathrate reservoir hypothesis for Enceladus' south polar plume.

Kieffer, Lu, Bethke, Spencer, Marshak, Navrotsky; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Microbiology. Ramping up the heat on nitrogenase.

Capone; (Journal Article)

Sequential interplay of nicotinic and GABAergic signaling guides neuronal development.

Liu, Neff, Berg; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Chemistry. Pulling strings.

Fontana; (Comment, Journal Article)

Geochemistry. A shot of oxygen to unleash the evolution of animals.

Kerr; (News)

A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii.

Taylor, Barragan, Su, Fux, Fentress, Tang, Beatty, Hajj, Jerome, Behnke, White, Wootton, Sibley; (Journal Article, Research Support, N.I.H., Extramural, Research Support, N.I.H., Intramural, Research Support, Non-U.S. Gov't)

Using models to manage carnivores.

Chapron, Arlettaz; (Letter)

A Semi-Empirical Approach to Projecting Future Sea-Level Rise.

Rahmstorf; (JOURNAL ARTICLE)

Data mining on the web.

Smith, Gerstein; (Comment, Letter)

Group competition, reproductive leveling, and the evolution of human altruism.

Bowles; (Journal Article, Research Support, Non-U.S. Gov't)

Stem cell research. A season of generosity...and jeremiads.

Enserink; (News)

U.S. research spending. Congress extends tax credits for industry.

none; (News)

Retraction.

Lezcano, Bergson, Mrzljak, Levenson; (Retraction of Publication)

Research and development. Where is the new science in corporate R&D?

Thursby, Thursby; (Journal Article, Research Support, Non-U.S. Gov't)


Nature Methods


Nature Biotechnology

The real deal.

Bialy; (JOURNAL ARTICLE)

Reply to "The art of gene function prediction".

none; (Journal Article)

Reinventing phage therapy: are the parts greater than the sum?

Fischetti, Nelson, Schuch; (Journal Article)

Profile of a bacterial tumor killer.

Forbes; (Journal Article)

Biotech takes aim at large anti-estrogen markets.

Hollmer; (Journal Article)

Biotech blockbusters consolidate markets.

Lawrence; (Journal Article)

Recent patent applications related to antibacterials.

none; (Journal Article)

European pharma consolidation generates quality spinoffs.

Sheridan; (Journal Article)

Molecular engineering approaches to peptide, polyketide and other antibiotics.

Baltz; (Journal Article)

Is there balm in Gilead?

Jacobs; (Journal Article)

Moving goalposts-regulatory oversight of antibacterial drugs.

Brenner, Ellis-Grosse, Echols; (JOURNAL ARTICLE)

NCBI GEO standards and services for microarray data.

Edgar, Barrett; (Journal Article)

Research highlights.

none; (Journal Article)

News in brief.

none; (Journal Article)

A billion dollar punt.

none; (Journal Article)

Antibiotics-an investment worth making?

Christoffersen; (JOURNAL ARTICLE)

New antibiotics from bacterial natural products.

Clardy, Fischbach, Walsh; (Journal Article)

Maximizing state and federal spending while minimizing conflicts.

Billingsley, Washko; (JOURNAL ARTICLE)

The art of gene function prediction.

Murali, Wu, Kasif; (Journal Article)

Anti-infective antibodies: finding the path forward.

Baker; (Journal Article)

Why the omega-3 piggy should not go to market.

Fiester; (Journal Article)

Big pharma wants you.

Mack; (Journal Article)

Antibacterial discovery and development-the failure of success?

Fernandes; (Journal Article)

Executive compensation at private biotech companies: beyond hearsay.

Rychlik, Dipierro; (Journal Article)

What is a support vector machine?

Noble; (Journal Article)

A new lease on life for dendritic cell vaccines?

Nestle; (Journal Article)

Reproducibility Probability Score-incorporating measurement variability across laboratories for gene selection.

Lin, He, Ji, Shi, Davis, Zhong; (Journal Article)

People.

none; (Journal Article)

Towards cell therapy for diabetes.

Madsen, Serup; (Journal Article)

The business of developing antibacterials.

Fox; (Journal Article)

Danish biotech outperforms its European counterparts.

Moran; (Journal Article)

The pharma company view.

Brenner, Ellis-Grosse; (JOURNAL ARTICLE)

Antibiotics au naturel.

Sheridan; (Journal Article)

Prospects for plant-derived antibacterials.

Lewis, Ausubel; (Journal Article)

Riboswitches as antibacterial drug targets.

Blount, Breaker; (Journal Article)

Niche indications could drive higher valuations.

Ransom; (Journal Article)

All together now?

none; (Journal Article)

Bring the magic back to the bullets.

none; (Journal Article)

Profile: daphne zohar.

Ratner; (Journal Article)

Where have all the antibiotic patents gone?

Katz, Mueller, Polyakov, Weinstock; (Journal Article)

Moving goalposts-regulatory oversightof antibacterial drugs.

Echols; (Journal Article)

Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies.

Hancock, Sahl; (Journal Article)


Nature Medicine

Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma.

Parsa, Waldron, Panner, Crane, Parney, Barry, Cachola, Murray, Tihan, Jensen, Mischel, Stokoe, Pieper; (JOURNAL ARTICLE)

Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors.

Rousseaux, Thuru, Gelot, Barnich, Neut, Dubuquoy, Dubuquoy, Merour, Geboes, Chamaillard, Ouwehand, Leyer, Carcano, Colombel, Ardid, Desreumaux; (JOURNAL ARTICLE)

NF-kappaB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF.

Park, Zhang, Zeng, Dai, Keller, Giordano, Gu, Shah, Pei, Zarbo, McCauley, Shi, Chen, Wang; (JOURNAL ARTICLE)

Chromosome 5q deletion and epigenetic suppression of the gene encoding alpha-catenin (CTNNA1) in myeloid cell transformation.

Liu, Becker, Jelinek, Wu, Deng, Mikhalkevich, Hsu, Bloomfield, Stone, Deangelo, Galinsky, Issa, Clarke, Look; (JOURNAL ARTICLE)


Nature Genetics

Genome-wide variation and identification of vaccine targets in the Plasmodium falciparum genome.

Mu, Awadalla, Duan, McGee, Keebler, Seydel, McVean, Su; (JOURNAL ARTICLE)

Convergent adaptation of human lactase persistence in Africa and Europe.

Tishkoff, Reed, Ranciaro, Voight, Babbitt, Silverman, Powell, Mortensen, Hirbo, Osman, Ibrahim, Omar, Lema, Nyambo, Ghori, Bumpstead, Pritchard, Wray, Deloukas; (JOURNAL ARTICLE)

Mutations in SYNE1 lead to a newly discovered form of autosomal recessive cerebellar ataxia.

Gros-Louis, Dupré, Dion, Fox, Laurent, Verreault, Sanes, Bouchard, Rouleau; (JOURNAL ARTICLE)

Genome variation and evolution of the malaria parasite Plasmodium falciparum.

Jeffares, Pain, Berry, Cox, Stalker, Ingle, Thomas, Quail, Siebenthall, Uhlemann, Kyes, Krishna, Newbold, Dermitzakis, Berriman; (JOURNAL ARTICLE)

A genome-wide map of diversity in Plasmodium falciparum.

Volkman, Sabeti, Decaprio, Neafsey, Schaffner, Milner, Daily, Sarr, Ndiaye, Ndir, Mboup, Duraisingh, Lukens, Derr, Stange-Thomann, Waggoner, Onofrio, Ziaugra, Mauceli, Gnerre, Jaffe, Zainoun, Wiegand, Birren, Hartl, Galagan, Lander, Wirth; (JOURNAL ARTICLE)


Molecular Medicine


Proteomics

Proteomic analysis of mouse growth plate cartilage.

Belluoccio, Wilson, Thornton, Wallis, Gorman, Bateman; (JOURNAL ARTICLE)

Proteomic and transcriptomic analyses of differential stress/inflammatory responses in mandibular lymph nodes and oropharyngeal tonsils of European wild boars naturally infected with Mycobacterium bovis.

Naranjo, Villar, Martín-Hernando, Vidal, Höfle, Gortazar, Kocan, Vázquez, de la Fuente; (JOURNAL ARTICLE)

PROTEOMICS Call for Reviews.

Dunn; (JOURNAL ARTICLE)

Chromosomal His-tagging: An alternative approach to membrane protein purification.

Mamelli, Dedieu, Dé, Konkel, Pagčs, Bolla; (JOURNAL ARTICLE)

Proteomic screening of glucose-responsive and glucose non-responsive MIN-6 beta cells reveals differential expression of proteins involved in protein folding, secretion and oxidative stress.

Dowling, O'driscoll, O'sullivan, Dowd, Henry, Jeppesen, Meleady, Clynes; (JOURNAL ARTICLE)

PROTEOMICS Acknowledgements: Proteomics 24/2006.

none; (JOURNAL ARTICLE)

Selective enrichment of Ser-/Thr-phosphorylated peptides in the presence of Ser-/Thr-glycosylated peptides.

Poot, Ruijter, Nuijens, Dirksen, Heck, Slijper, Rijkers, Liskamp; (JOURNAL ARTICLE)

Joel Margolis MB, BS, D Phil, D Sc, FRACPath 02.07.1920 - 02.04.2006 Pioneer in Proteomics, Coagulation, Citation indexing and Commercialization in Science.

Exner, Honeyman; (JOURNAL ARTICLE)

Proteomic responses of rice young panicles to salinity.

Dooki, Mayer-Posner, Askari, Zaiee, Salekdeh; (JOURNAL ARTICLE)

Overexpression of CLIC1 in human gastric carcinoma and its clinicopathological significance.

Chen, Wang, Huang, Chien, Liang, Chen, Lin; (JOURNAL ARTICLE)

Mapping the proteome of poplar and application to the discovery of drought-stress responsive proteins.

Plomion, Lalanne, Claverol, Meddour, Kohler, Bogeat-Triboulot, Barre, Le Provost, Dumazet, Jacob, Bastien, Dreyer, de Daruvar, Guehl, Schmitter, Martin, Bonneu; (JOURNAL ARTICLE)

Proteomic analysis reveals higher demand for antioxidant protection in embryonic stem cell-derived smooth muscle cells.

Yin, Mayr, Xiao, Wang, Xu; (JOURNAL ARTICLE)

Comparative proteomic approaches for the isolation of proteins interacting with thioredoxin.

Marchand, Le Maréchal, Meyer, Decottignies; (JOURNAL ARTICLE)

Proteomic analysis of human very low-density lipoprotein by two-dimensional gel electrophoresis and MALDI-TOF/TOF.

Mancone, Amicone, Fimia, Bravo, Piacentini, Tripodi, Alonzi; (JOURNAL ARTICLE)

Identification of proteins interacting with the catalytic subunit of PP2A by proteomics.

Lee, Kim, Lee, Choi; (JOURNAL ARTICLE)

NanoLC-FT-ICR MS improves proteome coverage attainable for 3000 laser-microdissected breast carcinoma cells.

Umar, Luider, Foekens, Paša-Tolić; (JOURNAL ARTICLE)

Cyclin I and p53 are differentially expressed during the terminal differentiation of the postnatal mouse heart.

Liu, Tang, Cai, Li, Wong, Chow, Lee; (JOURNAL ARTICLE)

Structural protein analysis of the polyvalent staphylococcal bacteriophage 812.

Eyer, Pantůček, Zdráhal, Konečná, Kašpárek, Růžičková, Hernychová, Preisler, Doškař; (JOURNAL ARTICLE)

AFM fishing nanotechnology is the way to reverse the Avogadro number in proteomics.

Archakov, Ivanov, Lisitsa, Zgoda; (JOURNAL ARTICLE)

In this issue: Proteomics 24/2006.

none; (JOURNAL ARTICLE)


Nature Drug Discovery


BMC Bioinformatics

The NeuARt II system: a viewing tool for neuroanatomical data based on published neuroanatomical atlases.

Burns, Cheng, Thompson, Swanson; (JOURNAL ARTICLE)

Model-driven user interfaces for bioinformatics data resources: regenerating the wheel as an alternative to reinventing it.

Garwood, Garwood, Hedeler, Griffiths, Swainston, Oliver, Paton; (JOURNAL ARTICLE)

MathDAMP: a package for differential analysis of metabolite profiles.

Baran, Kochi, Saito, Suematsu, Soga, Nishioka, Robert, Tomita; (JOURNAL ARTICLE)


Bioinformatics

Assembling millions of short DNA sequences using SSAKE.

Warren, Sutton, Jones, Holt; (JOURNAL ARTICLE)

Functional genomics via multiscale analysis: application to gene expression and ChIP-on-chip data.

Lerman, McQuown, Blais, Dynlacht, Chen, Mishra; (JOURNAL ARTICLE)

Causality and pathway search in microarray time series experiment.

Mukhopadhyay, Chatterjee; (JOURNAL ARTICLE)

GGtools: analysis of genetics of gene expression in Bioconductor.

Carey, Morgan, Falcon, Lazarus, Gentleman; (JOURNAL ARTICLE)

Segmentation and intensity estimation of microarray images using a gamma-t mixture model.

Baek, Son, McLachlan; (JOURNAL ARTICLE)

Quantitative performance metrics for robustness in circadian rhythms.

Bagheri, Stelling, Doyle; (JOURNAL ARTICLE)


Proc Natl Acad Sci U S A

Geniculocortical relay of blue-off signals in the primate visual system.

Szmajda, Buzás, Fitzgibbon, Martin; (JOURNAL ARTICLE)

Profile of Elinor Ostrom.

Zagorski; (JOURNAL ARTICLE)

Purified vitamin K epoxide reductase alone is sufficient for conversion of vitamin K epoxide to vitamin K and vitamin K to vitamin KH2.

Chu, Huang, Williams, Stafford; (JOURNAL ARTICLE)

Epstein-Barr nuclear antigen leader protein coactivates transcription through interaction with histone deacetylase 4.

Portal, Rosendorff, Kieff; (JOURNAL ARTICLE)

Impairments in frontal cortical {gamma} synchrony and cognitive control in schizophrenia.

Cho, Konecky, Carter; (JOURNAL ARTICLE)

An approach to designing a national climate service.

Miles, Snover, Whitely Binder, Sarachik, Mote, Mantua; (JOURNAL ARTICLE)

Global mammal distributions, biodiversity hotspots, and conservation.

Ceballos, Ehrlich; (JOURNAL ARTICLE)

Sequence-specific modification of mitochondrial DNA using a chimeric zinc finger methylase.

Minczuk, Papworth, Kolasinska, Murphy, Klug; (JOURNAL ARTICLE)

Flux control and excess capacity in the enzymes of glycolysis and their relationship to flight metabolism in Drosophila melanogaster.

Eanes, Merritt, Flowers, Kumagai, Sezgin, Zhu; (JOURNAL ARTICLE)

Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators.

Ju, Kim, Bi, Meng, Bai, Li, Li, Marma, Shi, Wu, Edwards, Romu, Turro; (JOURNAL ARTICLE)

Paleobiology and comparative morphology of a late Neandertal sample from El Sidron, Asturias, Spain.

Rosas, Martínez-Maza, Bastir, García-Tabernero, Lalueza-Fox, Huguet, Ortiz, Juliŕ, Soler, de Torres, Martínez, Cańaveras, Sánchez-Moral, Cuezva, Lario, Santamaría, de la Rasilla, Fortea; (JOURNAL ARTICLE)

The wheat and barley vernalization gene VRN3 is an orthologue of FT.

Yan, Fu, Li, Blechl, Tranquilli, Bonafede, Sanchez, Valarik, Yasuda, Dubcovsky; (JOURNAL ARTICLE)

Identification of alterations in DNA copy number in host stromal cells during tumor progression.

Pelham, Rodgers, Hall, Lucito, Nguyen, Navin, Hicks, Mu, Powers, Wigler, Botstein; (JOURNAL ARTICLE)

Two overrepresented B cell populations in HIV-infected individuals undergo apoptosis by different mechanisms.

Ho, Moir, Malaspina, Howell, Wang, Dipoto, O'shea, Roby, Kwan, Mican, Chun, Fauci; (JOURNAL ARTICLE)

Identification of a large noncoding RNA in extremophilic eubacteria.

Puerta-Fernandez, Barrick, Roth, Breaker; (JOURNAL ARTICLE)

Aboveground sink strength in forests controls the allocation of carbon below ground and its [CO2]-induced enhancement.

Palmroth, Oren, McCarthy, Johnsen, Finzi, Butnor, Ryan, Schlesinger; (JOURNAL ARTICLE)

Small worlds inside big brains.

Sporns, Honey; (JOURNAL ARTICLE)

Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins.

Li, Mustafi, Fu, Tereshko, Chen, Tice, Ismagilov; (JOURNAL ARTICLE)

Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages.

Perera, Zoncu, Lucast, De Camilli, Toomre; (JOURNAL ARTICLE)

The discordant eardrum.

P Fay, Puria, Steele; (JOURNAL ARTICLE)

Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging.

Hyun, Emerson, Jo, Mattson, de Cabo; (JOURNAL ARTICLE)

Sometimes area counts more than number.

Hurewitz, Gelman, Schnitzer; (JOURNAL ARTICLE)

RNA silencing of host transcripts by cauliflower mosaic virus requires coordinated action of the four Arabidopsis Dicer-like proteins.

Moissiard, Voinnet; (JOURNAL ARTICLE)

Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis.

Miller, Kim, Yamanaka, Hester, Umapathi, Arnson, Rizo, Mendell, Gage, Cleveland, Kaspar; (JOURNAL ARTICLE)

Integrated model shows that atmospheric brown clouds and greenhouse gases have reduced rice harvests in India.

Auffhammer, Ramanathan, Vincent; (JOURNAL ARTICLE)

Polyoma and SV40 proteins differentially regulate PP2A to activate distinct cellular signaling pathways involved in growth control.

Rodriguez-Viciana, Collins, Fried; (JOURNAL ARTICLE)

A fully integrated microfluidic genetic analysis system with sample-in-answer-out capability.

Easley, Karlinsey, Bienvenue, Legendre, Roper, Feldman, Hughes, Hewlett, Merkel, Ferrance, Landers; (JOURNAL ARTICLE)

Multiple intermediates in SNARE-induced membrane fusion.

Yoon, Okumus, Zhang, Shin, Ha; (JOURNAL ARTICLE)

Analysis of cartilage matrix fixed charge density and three-dimensional morphology via contrast-enhanced microcomputed tomography.

Palmer, Guldberg, Levenston; (JOURNAL ARTICLE)

Evolutionary constraint on Otx2 neuroectoderm enhancers-deep conservation from skate to mouse and unique divergence in teleost.

Kurokawa, Sakurai, Inoue, Nakayama, Takasaki, Suda, Miyake, Amemiya, Aizawa; (JOURNAL ARTICLE)

The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma.

Podar, Tonon, Sattler, Tai, Legouill, Yasui, Ishitsuka, Kumar, Kumar, Pandite, Hideshima, Chauhan, Anderson; (JOURNAL ARTICLE)

Binding then bending: A mechanism for wrapping DNA.

Khrapunov, Brenowitz, Rice, Catalano; (JOURNAL ARTICLE)

Nitric oxide synthase generates nitric oxide locally to regulate compartmentalized protein S-nitrosylation and protein trafficking.

Iwakiri, Satoh, Chatterjee, Toomre, Chalouni, Fulton, Groszmann, Shah, Sessa; (JOURNAL ARTICLE)

Human lupus autoantibodies against NMDA receptors mediate cognitive impairment.

Kowal, Degiorgio, Lee, Edgar, Huerta, Volpe, Diamond; (JOURNAL ARTICLE)

A route for fructose utilization by Escherichia coli involving the fucose regulon.

Kornberg, Lourenco; (JOURNAL ARTICLE)

Structure of a bacterial pyridoxal 5'-phosphate synthase complex.

Strohmeier, Raschle, Mazurkiewicz, Rippe, Sinning, Fitzpatrick, Tews; (JOURNAL ARTICLE)

Conservation of the metabolomic response to starvation across two divergent microbes.

Brauer, Yuan, Bennett, Lu, Kimball, Botstein, Rabinowitz; (JOURNAL ARTICLE)

Hypoglycemia leads to age-related loss of vision.

Umino, Everhart, Solessio, Cusato, Pan, Nguyen, Brown, Hafler, Frio, Knox, Engbretson, Haeri, Cui, Glenn, Charron, Barlow; (JOURNAL ARTICLE)

CD27 mediates interleukin-2-independent clonal expansion of the CD8+ T cell without effector differentiation.

Carr, Carrasco, Thaventhiran, Bambrough, Kraman, Edwards, Al-Shamkhani, Fearon; (JOURNAL ARTICLE)

Environmental change and infectious disease: How new roads affect the transmission of diarrheal pathogens in rural Ecuador.

Eisenberg, Cevallos, Ponce, Levy, Bates, Scott, Hubbard, Vieira, Endara, Espinel, Trueba, Riley, Trostle; (JOURNAL ARTICLE)

Polycomb recruitment to DNA in vivo by the YY1 REPO domain.

Wilkinson, Park, Atchison; (JOURNAL ARTICLE)

Evolutionary theory for modifiers of epistasis using a general symmetric model.

Liberman, Feldman; (JOURNAL ARTICLE)

Three-dimensional equilibria in axially symmetric tokamaks.

Garabedian; (JOURNAL ARTICLE)

Selectivity for the configural cues that identify the gender, ethnicity, and identity of faces in human cortex.

Ng, Ciaramitaro, Anstis, Boynton, Fine; (JOURNAL ARTICLE)

p21 delays tumor onset by preservation of chromosomal stability.

Barboza, Liu, Ju, El-Naggar, Lozano; (JOURNAL ARTICLE)

Multiwalled ice helixes and ice nanotubes.

Bai, Wang, Zeng; (JOURNAL ARTICLE)

Combinatorial pattern recognition receptor signaling alters the balance of life and death in macrophages.

Seimon, Obstfeld, Moore, Golenbock, Tabas; (JOURNAL ARTICLE)

Phosphorylation of the ATP-binding loop directs oncogenicity of drug-resistant BCR-ABL mutants.

Skaggs, Gorre, Ryvkin, Burgess, Xie, Han, Komisopoulou, Brown, Loo, Landaw, Sawyers, Graeber; (JOURNAL ARTICLE)

Why molecules move along a temperature gradient.

Duhr, Braun; (JOURNAL ARTICLE)

Amyloid of the prion domain of Sup35p has an in-register parallel {beta}-sheet structure.

Shewmaker, Wickner, Tycko; (JOURNAL ARTICLE)

Delay of T cell senescence by caloric restriction in aged long-lived nonhuman primates.

Messaoudi, Warner, Fischer, Park, Hill, Mattison, Lane, Roth, Ingram, Picker, Douek, Mori, Nikolich-Zugich; (JOURNAL ARTICLE)

Canopy leaf area constrains [CO2]-induced enhancement of productivity and partitioning among aboveground carbon pools.

McCarthy, Oren, Finzi, Johnsen; (JOURNAL ARTICLE)

Presenilin mutations linked to familial Alzheimer's disease cause an imbalance in phosphatidylinositol 4,5-bisphosphate metabolism.

Landman, Jeong, Shin, Voronov, Serban, Kang, Park, Di Paolo, Chung, Kim; (JOURNAL ARTICLE)

Axonal mRNA transport and localized translational regulation of {kappa}-opioid receptor in primary neurons of dorsal root ganglia.

Bi, Tsai, Lin, Loh, Wei; (JOURNAL ARTICLE)

Epstein-Barr virus nuclear protein EBNA3C is required for cell cycle progression and growth maintenance of lymphoblastoid cells.

Maruo, Wu, Ishikawa, Kanda, Iwakiri, Takada; (JOURNAL ARTICLE)

Gene cooption without duplication during the evolution of a male-pregnancy gene in pipefish.

Harlin-Cognato, Hoffman, Jones; (JOURNAL ARTICLE)

Carboxyl-modified single-walled carbon nanotubes selectively induce human telomeric i-motif formation.

Li, Peng, Ren, Qu; (JOURNAL ARTICLE)

Molecular identification of microsomal acyl-CoA:glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesis.

Cao, Li, Li, Tobin, Gimeno; (JOURNAL ARTICLE)

A cancer-associated PCNA expressed in breast cancer has implications as a potential biomarker.

Malkas, Herbert, Abdel-Aziz, Dobrolecki, Liu, Agarwal, Hoelz, Badve, Schnaper, Arnold, Mechref, Novotny, Loehrer, Goulet, Hickey; (JOURNAL ARTICLE)

Opposite patterns of hemisphere dominance for early auditory processing of lexical tones and consonants.

Luo, Ni, Li, Li, Zhang, Zeng, Chen; (JOURNAL ARTICLE)

High-sensitivity detection of TNT.

Pushkarsky, Dunayevskiy, Prasanna, Tsekoun, Go, Patel; (JOURNAL ARTICLE)

Developmental stage-specific biphasic roles of Wnt/{beta}-catenin signaling in cardiomyogenesis and hematopoiesis.

Naito, Shiojima, Akazawa, Hidaka, Morisaki, Kikuchi, Komuro; (JOURNAL ARTICLE)

Discrete Radon transform has an exact, fast inverse and generalizes to operations other than sums along lines.

Press; (JOURNAL ARTICLE)

TNF{alpha} kinoid vaccination-induced neutralizing antibodies to TNF{alpha} protect mice from autologous TNF{alpha}-driven chronic and acute inflammation.

Le Buanec, Delavallée, Bessis, Paturance, Bizzini, Gallo, Zagury, Boissier; (JOURNAL ARTICLE)

Predicting the global spread of H5N1 avian influenza.

Kilpatrick, Chmura, Gibbons, Fleischer, Marra, Daszak; (JOURNAL ARTICLE)

TRP channel activation by reversible covalent modification.

Hinman, Chuang, Bautista, Julius; (JOURNAL ARTICLE)

Forest fire increases mercury accumulation by fishes via food web restructuring and increased mercury inputs.

Kelly, Schindler, St Louis, Donald, Vladicka; (JOURNAL ARTICLE)

Bursts of nonsynonymous substitutions in HIV-1 evolution reveal instances of positive selection at conservative protein sites.

Bazykin, Dushoff, Levin, Kondrashov; (JOURNAL ARTICLE)

Identification of a biomarker for sleep drive in flies and humans.

Seugnet, Boero, Gottschalk, Duntley, Shaw; (JOURNAL ARTICLE)

Adaptive reconfiguration of fractal small-world human brain functional networks.

Bassett, Meyer-Lindenberg, Achard, Duke, Bullmore; (JOURNAL ARTICLE)

Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome.

Johnson, Bernal-Mizrachi, Alejandro, Han, Kalynyak, Li, Beith, Gross, Warnock, Townsend, Permutt, Polonsky; (JOURNAL ARTICLE)

Estrogen receptor {beta} expression in the embryonic brain regulates development of calretinin-immunoreactive GABAergic interneurons.

Fan, Warner, Gustafsson; (JOURNAL ARTICLE)

Azoospermia in mice with targeted disruption of the Brek/Lmtk2 (brain-enriched kinase/lemur tyrosine kinase 2) gene.

Kawa, Ito, Toyama, Maekawa, Tezuka, Nakamura, Nakazawa, Yokoyama, Yoshida, Toshimori, Yamamoto; (JOURNAL ARTICLE)

Miocene mammal reveals a Mesozoic ghost lineage on insular New Zealand, southwest Pacific.

Worthy, Tennyson, Archer, Musser, Hand, Jones, Douglas, McNamara, Beck; (JOURNAL ARTICLE)

Tsunami inundation modeling for western Sumatra.

Borrero, Sieh, Chlieh, Synolakis; (JOURNAL ARTICLE)

Role of molecular charge and hydrophilicity in regulating the kinetics of crystal growth.

Elhadj, De Yoreo, Hoyer, Dove; (JOURNAL ARTICLE)


N Engl J Med

The value of medical spending in the United States.

Braithwaite, Roberts; (Comment, Historical Article, Letter)

Different approaches to influenza vaccination.

Fukuda, Kieny; (Comment, Editorial)

The eradication of polio--progress and challenges.

Pallansch, Sandhu; (Journal Article)

A risk score for predicting death in Chagas' heart disease.

Focosi; (Comment, Letter)

The value of medical spending in the United States.

Goozner; (Comment, Historical Article, Letter)

HIV injustice in Libya--scapegoating foreign medical professionals.

Rosenthal; (Journal Article)

The state of primary care.

Das, Moorthi; (Comment, Letter)

Cytokine storm and an anti-CD28 monoclonal antibody.

Garcia-Bournissen, Boragina, Ito; (Comment, Letter)

A risk score for predicting death in Chagas' heart disease.

Viotti, Vigliano, Armenti; (Comment, Letter)

The state of primary care.

Poplin; (Comment, Letter)

Prevention of antigenically drifted influenza by inactivated and live attenuated vaccines.

Ohmit, Victor, Rotthoff, Teich, Truscon, Baum, Rangarajan, Newton, Boulton, Monto; (Journal Article, Randomized Controlled Trial, Research Support, N.I.H., Extramural)

T-cell costimulation.

Wise, Gallimore, Godkin; (Comment, Letter)

Images in clinical medicine. Abnormal eye movements associated with unilateral loss of vestibular function.

Lewis, Carey; (Journal Article)

Images in clinical medicine. Arterial microaneurysms in polyarteritis nodosa.

Das, Pangtey; (Journal Article)

Medical progress: Acromegaly.

Melmed; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

The state of primary care.

Chretien; (Comment, Letter)

A risk score for predicting death in Chagas' heart disease.

Kamath, Drazner; (Comment, Letter)

T-cell costimulation.

Colaco; (Comment, Letter)

Clinical practice. Adenomatous polyps of the colon.

Levine, Ahnen; (Journal Article)

The state of primary care.

Fields, Kirk; (Comment, Letter)

Treatment of rectal cancer.

Cromwell, Santiago, Marcet; (Comment, Letter)

Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer.

Sandler, Gray, Perry, Brahmer, Schiller, Dowlati, Lilenbaum, Johnson; (Journal Article, Research Support, N.I.H., Extramural)

DNA repair by ERCC1 in non-small-cell lung cancer.

Cecere, Bria, Rosell; (Comment, Letter)

Treatment of rectal cancer.

Curigliano, Spitaleri, Zampino; (Comment, Letter)

The state of primary care.

Becker, Carleton, Lin; (Comment, Letter)

Drug-eluting stents in primary PCI.

Jneid, Maree, Palacios; (Comment, Letter)

The state of primary care.

Oserman; (Comment, Letter)

Case records of the Massachusetts General Hospital. Case 38-2006. A 5-year-old boy with headache and abdominal pain.

Caviness, Sagar, Israel, Mackool, Grabowski, Frosch; (Clinical Conference, Journal Article)

DNA repair by ERCC1 in non-small-cell lung cancer.

Wilcox; (Comment, Letter)

Cytokine storm and an anti-CD28 monoclonal antibody.

Takita, Matsumura, Kami; (Comment, Letter)

A call to action--measuring the quality of colonoscopy.

Lieberman; (Comment, Editorial)

Heparin-induced thrombocytopenia.

Saad; (Comment, Letter)

Hormone replacement and the risk of breast cancer in Turner's syndrome.

Bösze, Tóth, Török; (Letter)

Drug-eluting stents in primary PCI.

Valgimigli, Percoco, Bolognese; (Comment, Letter)

Colonoscopic withdrawal times and adenoma detection during screening colonoscopy.

Barclay, Vicari, Doughty, Johanson, Greenlaw; (Journal Article)

Treatment of rectal cancer.

Hoecht, Hinkelbein; (Comment, Letter)

Cytokine storm and an anti-CD28 monoclonal antibody.

Gardner; (Comment, Letter)

Cytokine storm and an anti-CD28 monoclonal antibody.

Puellmann, Beham, Kaminski; (Comment, Letter)

Cytokine storm and an anti-CD28 monoclonal antibody.

Corry, Lewis; (Comment, Letter)

DNA repair by ERCC1 in non-small-cell lung cancer.

Grenader, Shavit; (Comment, Letter)

Effectiveness of school-based influenza vaccination.

King, Stoddard, Gaglani, Moore, Magder, McClure, Rubin, Englund, Neuzil; (Journal Article, Research Support, Non-U.S. Gov't)


J Natl Cancer Inst


Lancet

The Democrats' turn to lead.

none; (Editorial)

The MEGA study.

Moriguchi, Uemura, Sato; (Comment, Letter)

"Smart boys" and "sweet girls"--sex education needs in Thai teenagers: a mixed-method study.

Vuttanont, Greenhalgh, Griffin, Boynton; (Journal Article)

Oesophageal perforation with asymptomatic lung abscess formation.

Mawdsley, Maleki, Benjamin, Gupta, Adams, Bansi; (Journal Article)

Clinical presentation and pre-mortem diagnosis of variant Creutzfeldt-Jakob disease associated with blood transfusion: a case report.

Wroe, Pal, Siddique, Hyare, Macfarlane, Joiner, Linehan, Brandner, Wadsworth, Hewitt, Collinge; (Journal Article, Research Support, Non-U.S. Gov't)

The DREAM trial.

Yudkin; (Comment, Letter)

Screening mammography at 40-49 years: regret or no regret?

Djulbegovic, Lyman; (Comment, Journal Article)

Global guidelines: is gastroenterology leading the way?

Fried, Farthing, Krabshuis, Quigley; (Journal Article)

The MEGA study.

Strandberg; (Comment, Letter)

Democratic victory could fire up US health policy debates.

Bristol; (News)

The MEGA study.

Nango, Saio, Yuasa; (Comment, Letter)

Effect of mammographic screening from age 40 years on breast cancer mortality at 10 years' follow-up: a randomised controlled trial.

Moss, Cuckle, Evans, Johns, Waller, Bobrow; (Journal Article, Research Support, Non-U.S. Gov't)

The MEGA study - Authors' reply.

Nakamura; (LETTER)

Cholesterol: the good, the bad, and the stopped trials.

none; (Editorial)

The DREAM trial.

Herder, Martin, Kempf, Rose, Kolb; (Comment, Letter)

The DREAM trial - Authors' reply.

Gerstein, Yusuf, Bosch; (LETTER)

Sexual and reproductive health for all: a call for action.

Fathalla, Sinding, Rosenfield, Fathalla; (Journal Article)

Health in an unequal world.

Sir Michael Marmot; (Journal Article)

Global strategies need truly global discussions.

none; (Editorial)

Sima Samar: safeguarding human rights in Afghanistan.

Oransky; (News)

Management of the politics of evidence-based sexual and reproductive health policy.

Buse, Martin-Hilber, Widyantoro, Hawkes; (Journal Article)

The DREAM trial.

Nissen; (Comment, Letter)

A third episode of transfusion-derived vCJD.

Wilson, Ricketts; (Comment, Journal Article)

Optimum chemotherapy for metastatic colorectal cancer.

Bendell; (Journal Article)

The DREAM trial.

Lubsen, Poole-Wilson; (Comment, Letter)


Expert Rev Mol Diagn