Nature

Malaria: a protective paradox.

Hoffman; (Comment, News)

Genome-wide atlas of gene expression in the adult mouse brain.

Lein, Hawrylycz, Ao, Ayres, Bensinger, Bernard, Boe, Boguski, Brockway, Byrnes, Chen, Chen, Chen, Chi Chin, Chong, Crook, Czaplinska, Dang, Datta, Dee, Desaki, Desta, Diep, Dolbeare, Donelan, Dong, Dougherty, Duncan, Ebbert, Eichele, Estin, Faber, Facer, Fields, Fischer, Fliss, Frensley, Gates, Glattfelder, Halverson, Hart, Hohmann, Howell, Jeung, Johnson, Karr, Kawal, Kidney, Knapik, Kuan, Lake, Laramee, Larsen, Lau, Lemon, Liang, Liu, Luong, Michaels, Morgan, Morgan, Mortrud, Mosqueda, Ng, Ng, Orta, Overly, Pak, Parry, Pathak, Pearson, Puchalski, Riley, Rockett, Rowland, Royall, Ruiz, Sarno, Schaffnit, Shapovalova, Sivisay, Slaughterbeck, Smith, Smith, Smith, Sodt, Stewart, Stumpf, Sunkin, Sutram, Tam, Teemer, Thaller, Thompson, Varnam, Visel, Whitlock, Wohnoutka, Wolkey, Wong, Wood, Yaylaoglu, Young, Youngstrom, Feng Yuan, Zhang, Zwingman, Jones; (JOURNAL ARTICLE)

Creationists weaken society's trust in scientists.

Rutkowska; (Comment, Letter)

News in brief.

none; (JOURNAL ARTICLE)

Active galactic nuclei as scaled-up Galactic black holes.

McHardy, Koerding, Knigge, Uttley, Fender; (Journal Article, Research Support, Non-U.S. Gov't)

Purdue attacked over fusion inquiry.

Reich; (News)

A fair share.

none; (Editorial)

Evolutionary biology: caught right-handed.

Palmer; (News)

Research highlights.

none; (JOURNAL ARTICLE)

The circumsporozoite protein is an immunodominant protective antigen in irradiated sporozoites.

Kumar, Sano, Boscardin, Nussenzweig, Nussenzweig, Zavala, Nussenzweig; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

How the word 'hominid' evolved to include hominin.

Underdown; (Letter)

Definitive fossil evidence for the extant avian radiation in the Cretaceous.

Clarke, Tambussi, Noriega, Erickson, Ketcham; (Journal Article)

Astrophysics: unity among black holes.

Wilms; (Comment, News)

In retrospect: The birth of contraception.

Raymond; (JOURNAL ARTICLE)

A timely wake-up call as anti-evolutionists publicize their views.

Kutschera; (Comment, Letter)

Enough warheads, already.

none; (Editorial)

Chemical biology: renewing embryonic stem cells.

Letso, Stockwell; (News)

Electrical activity in early neuronal development.

Spitzer; (Journal Article)

The efficient interaction of indirect reciprocity and costly punishment.

Rockenbach, Milinski; (Journal Article, Research Support, Non-U.S. Gov't)

US biofuels: a field in ferment.

Sanderson; (Journal Article)

Pseudoscience should not be published in Nature.

Balthasar, Maidment; (Comment, Letter)

Oxidation of the Ediacaran ocean.

Fike, Grotzinger, Pratt, Summons; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Abstractions.

none; (JOURNAL ARTICLE)

Molecular HIV evidence backs accused medics.

Butler; (News)

Astrochemistry: Complex organic matter in Titan's aerosols?

Biemann; (Comment, Journal Article)

Navigation: bat orientation using Earth's magnetic field.

Holland, Thorup, Vonhof, Cochran, Wikelski; (Journal Article)

Introduction: biofuelling the future.

none; (Journal Article)

Insights into the dynamics of mantle plumes from uranium-series geochemistry.

Bourdon, Ribe, Stracke, Saal, Turner; (Journal Article, Research Support, Non-U.S. Gov't)

Continental Runoff: a quality-controlled global runoff data set.

Peel, McMahon; (Comment, Journal Article)

Actions speak louder than images.

Mandavilli; (News)

Condensed-matter physics: defects and perfect flows.

Glyde; (Comment, News)

Claim of bias against critics is refuted by publication.

de Jong, Korthof; (Comment, Letter)

Controlled injection and acceleration of electrons in plasma wakefields by colliding laser pulses.

Faure, Rechatin, Norlin, Lifschitz, Glinec, Malka; (Journal Article, Research Support, Non-U.S. Gov't)

Smad4 signalling in T cells is required for suppression of gastrointestinal cancer.

Kim, Li, Qiao, Mamura, Kasprzak, Anver, Wolfraim, Hong, Mushinski, Potter, Kim, Fu, Deng, Letterio; (Journal Article)

Continental Runoff: A quality-controlled global runoff data set (Reply).

Gedney, Cox, Betts, Boucher, Huntingford, Stott; (Journal Article)

South Africa takes steps to tackle HIV.

Cherry; (News)

Green shoots of growth.

none; (Editorial)

Journal reveals plans to fight fraud.

Wadman; (News)

The critical role of disks in the formation of high-mass stars.

Cesaroni, Galli, Lodato, Walmsley, Zhang; (Journal Article)

Free fermion antibunching in a degenerate atomic Fermi gas released from an optical lattice.

Rom, Best, van Oosten, Schneider, Fölling, Paredes, Bloch; (Journal Article, Research Support, Non-U.S. Gov't)

Evolutionary Biology: Evidence for sympatric speciation? (Reply).

Barluenga, Stölting, Salzburger, Muschick, Meyer; (JOURNAL ARTICLE)

Liquid fuel synthesis: making it up as you go along.

Ledford; (Journal Article)

Chemistry: Metals line up for DNA.

Müller; (News)

50 & 100 Years Ago.

none; (JOURNAL ARTICLE)

Walking with dinosaurs? Not in the real world.

Hurd; (Comment, Letter)

Obituary: Reinhart Heinrich (1946-2006).

Kirschner; (JOURNAL ARTICLE)

Nectar bat stows huge tongue in its rib cage.

Muchhala; (Journal Article)

Thermal radiation scanning tunnelling microscopy.

De Wilde, Formanek, Carminati, Gralak, Lemoine, Joulain, Mulet, Chen, Greffet; (Journal Article, Research Support, Non-U.S. Gov't)

The right tools can save lives.

none; (Journal Article)

There is no new evidence that undermines evolution.

Charlesworth; (Comment, Letter)

Oceanography: Plankton in a warmer world.

Doney; (Comment, News)

Making the paper: Yannick De Wilde.

none; (JOURNAL ARTICLE)

Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells.

Piccirillo, Reynolds, Zanetti, Lamorte, Binda, Broggi, Brem, Olivi, Dimeco, Vescovi; (Journal Article, Research Support, Non-U.S. Gov't)

Sugar cane and ethanol: drink the best and drive the rest.

Marris; (Journal Article)

One good deed.

Curry; (JOURNAL ARTICLE)

Plasma physics: on the node of a wave.

Katsouleas; (Comment, News)

Creationists pose political, not scientific, threat.

Banbura; (Comment, Letter)

Film: The quest for immortality.

Marris; (JOURNAL ARTICLE)

A systems biology analysis of the Drosophila phagosome.

Stuart, Boulais, Charriere, Hennessy, Brunet, Jutras, Goyette, Rondeau, Letarte, Huang, Ye, Morales, Kocks, Bader, Desjardins, Ezekowitz; (JOURNAL ARTICLE)

US backs revamp of nuclear warheads.

Brumfiel; (News)

Oil firms back AIDS project in the Niger delta.

Macilwain; (News)

Key experiment.

none; (JOURNAL ARTICLE)

Awakening the genius within.

Gregory; (Journal Article)

The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNA.

Ye, Krug, Tao; (JOURNAL ARTICLE)

Bugs with bugs.

Winston; (JOURNAL ARTICLE)

Correction.

none; (JOURNAL ARTICLE)

Bush faces rough ride over climate change.

Marris; (News)

Climate-driven trends in contemporary ocean productivity.

Behrenfeld, O'Malley, Siegel, McClain, Sarmiento, Feldman, Milligan, Falkowski, Letelier, Boss; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Evolutionary Biology: evidence for sympatric speciation?

Schliewen, Kocher, McKaye, Seehausen, Tautz; (Comment, Journal Article)

Creationist views have no basis in science.

Lorenc-Plucińska; (Comment, Letter)

Sidelines.

none; (JOURNAL ARTICLE)

Cancer: stem cells and brain tumours.

Dirks; (Comment, News)


Science

Mitochondrial DNA and population size.

Wares, Barber, Ross-Ibarra, Sotka, Toonen; (Comment, Letter)


Nature Methods

Imaging cellular network dynamics in three dimensions using fast 3D laser scanning.

Göbel, Kampa, Helmchen; (JOURNAL ARTICLE)

Tomographic molecular imaging and 3D quantification within adult mouse organs.

Alanentalo, Asayesh, Morrison, Lorén, Holmberg, Sharpe, Ahlgren; (JOURNAL ARTICLE)


Nature Biotechnology

An essential role for Akt1 in dendritic cell function and tumor immunotherapy.

Park, Lapteva, Seethammagari, Slawin, Spencer; (Journal Article)


Nature Medicine

US marijuana laws clamping the lid on pot research.

Vastag; (Journal Article)

Reply to Natural killer T cells and CD8(+) T cells are dispensable for T cell-dependent allergic airway inflammation.

Akbari, Umetsu; (Journal Article)

Fat fuels insulin resistance through Toll-like receptors.

Tschöp, Thomas; (Journal Article)

Year-end Special.

none; (Journal Article)

Research highlights.

none; (Journal Article)

Skin controls immune regulators.

Yamaguchi, Sakaguchi; (Journal Article)

Epidermal RANKL controls regulatory T-cell numbers via activation of dendritic cells.

Loser, Mehling, Loeser, Apelt, Kuhn, Grabbe, Schwarz, Penninger, Beissert; (Journal Article)

Money matters.

none; (Journal Article)

Predictions.

none; (Journal Article)

Corrigendum: Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis.

Rossi, Sawatzky, Walker, Ward, Sheldrake, Riley, Caldicott, Martinez-Losa, Walker, Duffin, Gray, Crescenzi, Martin, Brady, Savill, Dransfield, Haslett; (Journal Article)

Rising drug costs prompt new uses for old pills.

Opar; (Journal Article)

Your dinner with peter.

Yewdell; (Journal Article)

New chief brings welcome change to US cancer agency.

Ready; (Journal Article)

You'll never believe it, but...

none; (Journal Article)

Alzheimer protease hitches a ride.

Wolfe; (Journal Article)

Lou Gehrig's group dangles million-dollar bait for biomarker search.

Waltz; (Journal Article)

Cancer gets the Chk'ered flag.

Cao, Finkel; (Journal Article)

Timeline of events ...a brief history of the important news stories this year.

none; (Journal Article)

Looking back.

none; (Journal Article)

Osteoclasts, no longer osteoblast slaves.

Boyce, Xing; (Journal Article)

News in brief.

none; (Journal Article)

Gut microbes out of control in HIV infection.

Haynes; (Journal Article)

Natural killer T cells and CD8(+) T cells are dispensable for T cell-dependent allergic airway inflammation.

Das, Eynott, Jupp, Bothwell, Van Kaer, Shi, Das; (Journal Article)

Quantitative micro positron emission tomography (PET) imaging for the in vivo determination of pancreatic islet graft survival.

Kim, Doudet, Studenov, Nian, Ruth, Gambhir, McIntosh; (Journal Article)

Breast cancer research neglects non-Jewish groups, experts charge.

Keim; (Journal Article)

Notable advances.

none; (Journal Article)


Nature Genetics

Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation.

Choudhury, Ju, Djojosubroto, Schienke, Lechel, Schaetzlein, Jiang, Stepczynska, Wang, Buer, Lee, von Zglinicki, Ganser, Schirmacher, Nakauchi, Rudolph; (JOURNAL ARTICLE)

PDGF signaling specificity is mediated through multiple immediate early genes.

Schmahl, Raymond, Soriano; (JOURNAL ARTICLE)

Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome.

Tartaglia, Pennacchio, Zhao, Yadav, Fodale, Sarkozy, Pandit, Oishi, Martinelli, Schackwitz, Ustaszewska, Martin, Bristow, Carta, Lepri, Neri, Vasta, Gibson, Curry, Siguero, Digilio, Zampino, Dallapiccola, Bar-Sagi, Gelb; (JOURNAL ARTICLE)

A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice.

Shima, Alcaraz, Liachko, Buske, Andrews, Munroe, Hartford, Tye, Schimenti; (JOURNAL ARTICLE)

Germline gain-of-function mutations in SOS1 cause Noonan syndrome.

Roberts, Araki, Swanson, Montgomery, Schiripo, Joshi, Li, Yassin, Tamburino, Neel, Kucherlapati; (JOURNAL ARTICLE)


Molecular Medicine


Proteomics

Effect of glycosylation on the protein pattern in 2-D-gel electrophoresis.

Kleinert, Kuster, Arnold, Jaeken, Heizmann, Troxler; (JOURNAL ARTICLE)

Phosphoproteins of the chicken eggshell calcified layer.

Mann, Olsen, MaÄŤek, Gnad, Mann; (JOURNAL ARTICLE)

Proteomic analysis of glutamate-induced toxicity in HT22 cells.

Lee, Park, Park, Cho, Myung, Park, Lee; (JOURNAL ARTICLE)

Multidimensional analysis of the insoluble sub-proteome of Oceanobacillus iheyensis HTE831, an alkaliphilic and halotolerant deep-sea bacterium isolated from the Iheya ridge.

Graham, Pollock, O'loughlin, Ternan, Weatherly, Tarleton, McMullan; (JOURNAL ARTICLE)

Banana (Musa spp.) as a model to study the meristem proteome: Acclimation to osmotic stress.

Carpentier, Witters, Laukens, Van Onckelen, Swennen, Panis; (JOURNAL ARTICLE)

Optimization of phosphopeptide elution conditions in immobilized Fe(III) affinity chromatography.

Imanishi, Kochin, Eriksson; (JOURNAL ARTICLE)

2-DE profiling of GDNF overexpression-related proteome changes in differentiating ST14A rat progenitor cells.

Hoffrogge, Beyer, Hübner, Mikkat, Mix, Scharf, Schmitz, Pauleweit, Berth, Zubrzycki, Christoph, Pahnke, Wolkenhauer, Uhrmacher, Völker, Rolfs; (JOURNAL ARTICLE)

Lipid raft proteome of the human neutrophil azurophil granule.

Feuk-Lagerstedt, Movitz, Pellmé, Dahlgren, Karlsson; (JOURNAL ARTICLE)

Feature-based reappraisal of the Bacillus subtilis exoproteome.

Tjalsma; (JOURNAL ARTICLE)

cTrans: Generating polypeptide databases from cDNA sequences.

Xu, Yang, Xu, Tao, Ma; (JOURNAL ARTICLE)

Faster and easier chromatin immunoprecipitation assay with high sensitivity.

Kohzaki, Murakami; (JOURNAL ARTICLE)

Evaluation of an in vitro model of androgen ablation and identification of the androgen responsive proteome in LNCaP cells.

Rowland, Robson, Simon, Leung, Slabas; (JOURNAL ARTICLE)


Nature Drug Discovery


BMC Bioinformatics

Fast estimation of the difference between two PAM/JTT evolutionary distances in triplets of homologous sequences.

Dessimoz, Gil, Schneider, Gonnet; (JOURNAL ARTICLE)

Chromosomal patterns of gene expression from microarray data: methodology, validation and clinical relevance in gliomas.

Turkheimer, Roncaroli, Hennuy, Herens, Nguyen, Martin, Evrard, Bours, Boniver, Deprez; (Journal Article)

Logarithmic gap costs decrease alignment accuracy.

Cartwright; (JOURNAL ARTICLE)

A specialized learner for inferring structured cis-regulatory modules.

Noto, Craven; (JOURNAL ARTICLE)


Bioinformatics

The automation of Nested Clade Phylogeographic Analysis.

Panchal; (JOURNAL ARTICLE)

Dynamic exploration and editing of KEGG pathway diagrams.

Klukas, Schreiber; (JOURNAL ARTICLE)

Markers improve clustering of CGH data.

Liu, Ranka, Kahveci; (JOURNAL ARTICLE)

AllerTool: a web server for predicting allergenicity and allergic cross-reactivity in proteins.

Zhang, Koh, Zhang, Choo, Tammi, Tong; (JOURNAL ARTICLE)

RelEx - relation extraction using dependency parse trees.

Fundel, Küffner, Zimmer; (JOURNAL ARTICLE)

msHOT: modifying Hudson's ms simulator to incorporate crossover and gene conversion hotspots.

Hellenthal, Stephens; (JOURNAL ARTICLE)

A distribution free summarization method for Affymetrix GeneChip(R) arrays.

Chen, McGee, Liu, Scheuermann; (JOURNAL ARTICLE)

cBrother: relaxing parental tree assumptions for Bayesian recombination detection.

Fang, Ding, Minin, Suchard, Dorman; (JOURNAL ARTICLE)

LdCompare: rapid computation of single- and multiple-marker r2 and genetic coverage.

Hao, Di, Cawley; (JOURNAL ARTICLE)

ADP_EM: fast exhaustive multi-resolution docking for high-throughput coverage.

Garzón, Kovacs, Abagyan, Chacón; (JOURNAL ARTICLE)

Exploiting large scale computing to construct high resolution linkage disequilibrium maps of the human genome.

Lau, Kuo, Tapper, Cox, Collins; (JOURNAL ARTICLE)

AutoGRAPH: an interactive web server for automating and visualizing comparative genome maps.

Derrien, André, Galibert, Hitte; (JOURNAL ARTICLE)

In silico identification of putative metal binding motifs.

Thilakaraj, Raghunathan, Anishetty, Pennathur; (JOURNAL ARTICLE)

Bioinformatics in the human interactome project.

Ideker, Valencia; (Journal Article)

Protein solubility: sequence based prediction and experimental verification.

Smialowski, Martin-Galiano, Mikolajka, Girschick, Holak, Frishman; (JOURNAL ARTICLE)

Genomic sweeping for hypermethylated genes.

Goh, Murphy, Muhkerjee, Furey; (JOURNAL ARTICLE)

Bayesian-based selection of metabolic objective functions.

Knorr, Jain, Srivastava; (JOURNAL ARTICLE)


Proc Natl Acad Sci U S A

Dominance of SOX9 function over RUNX2 during skeletogenesis.

Zhou, Zheng, Engin, Munivez, Chen, Sebald, Krakow, Lee; (Journal Article)

Influenza virus pleiomorphy characterized by cryoelectron tomography.

Harris, Cardone, Winkler, Heymann, Brecher, White, Steven; (Journal Article)

Atmospheric nitrogen deposition promotes carbon loss from peat bogs.

Bragazza, Freeman, Jones, Rydin, Limpens, Fenner, Ellis, Gerdol, Hájek, Hájek, Iacumin, Kutnar, Tahvanainen, Toberman; (JOURNAL ARTICLE)

Identification of a pathogenic antibody response to native myelin oligodendrocyte glycoprotein in multiple sclerosis.

Zhou, Srivastava, Nessler, Grummel, Sommer, Brück, Hartung, Stadelmann, Hemmer; (Journal Article)

From the Cover: Crosstalk between peroxisome proliferator-activated receptor {delta} and VEGF stimulates cancer progression.

Wang, Wang, Guo, Ning, Katkuri, Wahli, Desvergne, Dey, Dubois; (Journal Article)

Hydrolysis products of cAMP analogs cause transformation of Trypanosoma brucei from slender to stumpy-like forms.

Laxman, Riechers, Sadilek, Schwede, Beavo; (Journal Article)

Proteolytic processing of SDF-1{alpha} reveals a change in receptor specificity mediating HIV-associated neurodegeneration.

Vergote, Butler, Ooms, Cox, Silva, Hollenberg, Jhamandas, Overall, Power; (Journal Article)

Direct evidence for a prefrontal contribution to the control of proactive interference in verbal working memory.

Feredoes, Tononi, Postle; (JOURNAL ARTICLE)

Epidermal growth factor receptor tyrosine kinase is modulated by GM3 interaction with N-linked GlcNAc termini of the receptor.

Yoon, Nakayama, Hikita, Handa, Hakomori; (Journal Article)

Multivariate regression analysis of distance matrices for testing associations between gene expression patterns and related variables.

Zapala, Schork; (JOURNAL ARTICLE)

A system for quantifying dynamic protein interactions defines a role for Herceptin in modulating ErbB2 interactions.

Wehrman, Raab, Casipit, Doyonnas, Pomerantz, Blau; (Journal Article)

The Spemann organizer gene, Goosecoid, promotes tumor metastasis.

Hartwell, Muir, Reinhardt, Carpenter, Sgroi, Weinberg; (Journal Article)

Adhesion and friction in gecko toe attachment and detachment.

Tian, Pesika, Zeng, Rosenberg, Zhao, McGuiggan, Autumn, Israelachvili; (JOURNAL ARTICLE)

Differential effects of spermatogenesis and fertility in mice lacking androgen receptor in individual testis cells.

Tsai, Yeh, Wang, Yeh, Zhang, Lin, Tzeng, Chang; (Journal Article)

The Arabidopsis NRT1.1 transporter participates in the signaling pathway triggering root colonization of nitrate-rich patches.

Remans, Nacry, Pervent, Filleur, Diatloff, Mounier, Tillard, Forde, Gojon; (Journal Article)

Order N algorithm for computation of electrostatic interactions in biomolecular systems.

Lu, Cheng, Huang, McCammon; (JOURNAL ARTICLE)

Regions of I{kappa}B{alpha} that are critical for its inhibition of NF-{kappa}B{middle dot}DNA interaction fold upon binding to NF-{kappa}B.

Truhlar, Torpey, Komives; (Journal Article)

RNA-dependent conversion of phosphoserine forms selenocysteine in eukaryotes and archaea.

Yuan, Palioura, Salazar, Su, O'donoghue, Hohn, Cardoso, Whitman, Söll; (Journal Article)

A statistical approach to close packing of elastic rods and to DNA packaging in viral capsids.

Katzav, Adda-Bedia, Boudaoud; (Journal Article)

Exosite interactions contribute to tension-induced cleavage of von Willebrand factor by the antithrombotic ADAMTS13 metalloprotease.

Gao, Anderson, Majerus, Tuley, Sadler; (Journal Article)

Legionella pneumophila type II secretome reveals unique exoproteins and a chitinase that promotes bacterial persistence in the lung.

Debroy, Dao, Söderberg, Rossier, Cianciotto; (Journal Article)

ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease.

Ryu, Lee, Hagerty, Soh, McAlpin, Cormier, Smith, Ferrante; (Journal Article)

Plasma membrane-associated proteins are clustered into islands attached to the cytoskeleton.

Lillemeier, Pfeiffer, Surviladze, Wilson, Davis; (Journal Article)

Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange.

Weissmann, Dietrich, Fuchs, Kalwa, Ay, Dumitrascu, Olschewski, Storch, Mederos Y Schnitzler, Ghofrani, Schermuly, Pinkenburg, Seeger, Grimminger, Gudermann; (Journal Article)

Flavivirus nonstructural protein NS1: Complementary surprises.

Schlesinger; (Journal Article)

A robust measure of food web intervality.

Stouffer, Camacho, Amaral; (Journal Article)

Insight into the mechanism of biological methanol activation based on the crystal structure of the methanol-cobalamin methyltransferase complex.

Hagemeier, Krer, Thauer, Warkentin, Ermler; (Journal Article)

Wide-field subdiffraction imaging by accumulated binding of diffusing probes.

Sharonov, Hochstrasser; (Journal Article)

FHIT-proteasome degradation caused by mitogenic stimulation of the EGF receptor family in cancer cells.

Bianchi, Magnifico, Olgiati, Zanesi, Pekarsky, Tagliabue, Croce, Ménard, Campiglio; (Journal Article)

Existence of an operative pathway from the endoplasmic reticulum to the immature poxvirus membrane.

Husain, Weisberg, Moss; (JOURNAL ARTICLE)

Correction of hemophilia as a proof of concept for treatment of monogenic diseases by fetal spleen transplantation.

Aronovich, Tchorsh, Katchman, Eventov-Friedman, Shezen, Martinowitz, Blazar, Cohen, Tal, Reisner; (Journal Article)

Inhibition of MAPK stimulates the Ca2+-dependent big-conductance K channels in cortical collecting duct.

Li, Wang, Sun, Jin, Lin, Hebert, Giebisch, Wang; (JOURNAL ARTICLE)

From the Cover: Solution structure and dynamics of the complex between cytochrome c and cytochrome c peroxidase determined by paramagnetic NMR.

Volkov, Worrall, Holtzmann, Ubbink; (Journal Article)

Thymic rejuvenation and the induction of tolerance by adult thymic grafts.

Nobori, Shimizu, Okumi, Samelson-Jones, Griesemer, Hirakata, Sachs, Yamada; (Journal Article)

Compartmentalization of protein kinase A signaling by the heterotrimeric G protein Go.

Ghil, Choi, Kim, Lee, Liao, Birnbaumer, Suh-Kim; (Journal Article)

Release of autoinhibition converts ESCRT-III components into potent inhibitors of HIV-1 budding.

Zamborlini, Usami, Radoshitzky, Popova, Palu, Göttlinger; (Journal Article)

Balancing selection and the evolution of functional polymorphism in Old World monkey TRIM5{alpha}.

Newman, Hall, Connole, Chen, Sato, Yuste, Diehl, Hunter, Kaur, Miller, Johnson; (Journal Article)

Transgenic analysis of Dlx regulation in fish tooth development reveals evolutionary retention of enhancer function despite organ loss.

Jackman, Stock; (JOURNAL ARTICLE)

Two-dimensional vibrational optical probes for peptide fast folding investigation.

Zhuang, Abramavicius, Mukamel; (Journal Article)

Antibiotics as intermicrobial signaling agents instead of weapons.

Linares, Gustafsson, Baquero, Martinez; (JOURNAL ARTICLE)

Angiotensinergic stimulation of vascular endothelium in mice causes hypotension, bradycardia, and attenuated angiotensin response.

Ramchandran, Takezako, Saad, Stull, Fink, Yamada, Dikalov, Harrison, Moravec, Karnik; (Journal Article)

Crystal structure of apo-calmodulin bound to the first two IQ motifs of myosin V reveals essential recognition features.

Houdusse, Gaucher, Krementsova, Mui, Trybus, Cohen; (JOURNAL ARTICLE)

Almost all human genes resulted from ancient duplication.

Britten; (Journal Article)

The unique DKxanthene secondary metabolite family from the myxobacterium Myxococcus xanthus is required for developmental sporulation.

Meiser, Bode, Müller; (Journal Article)

Zfp423 controls proliferation and differentiation of neural precursors in cerebellar vermis formation.

Alcaraz, Gold, Raponi, Gent, Concepcion, Hamilton; (JOURNAL ARTICLE)

QnAs with Randy Schekman.

Zagorski; (Journal Article)

A physical analogue of the Schelling model.

Vinkovic, Kirman; (JOURNAL ARTICLE)

Expression of Aedes trypsin-modulating oostatic factor on the virion of TMV: A potential larvicide.

Borovsky, Rabindran, Dawson, Powell, Iannotti, Morris, Shabanowitz, Hunt, Debondt, Deloof; (Journal Article)

Rapid decay of tree-community composition in Amazonian forest fragments.

Laurance, Nascimento, Laurance, Andrade, Ribeiro, Giraldo, Lovejoy, Condit, Chave, Harms, D'Angelo; (Journal Article)

Synapse-specific regulation of AMPA receptor function by PSD-95.

Béďque, Lin, Kang, Aizawa, Takamiya, Huganir; (JOURNAL ARTICLE)

Mitochondrial uncoupling protein is required for efficient photosynthesis.

Sweetlove, Lytovchenko, Morgan, Nunes-Nesi, Taylor, Baxter, Eickmeier, Fernie; (JOURNAL ARTICLE)

Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes.

Legname, Nguyen, Peretz, Cohen, Dearmond, Prusiner; (Journal Article)

A polymorphism in the norepinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder.

Kim, Hahn, Joung, Anderson, Steele, Mazei-Robinson, Gizer, Teicher, Cohen, Robertson, Waldman, Blakely, Kim; (Journal Article)

Dynamics of global transcriptome in bovine matured oocytes and preimplantation embryos.

Misirlioglu, Page, Sagirkaya, Kaya, Parrish, First, Memili; (Journal Article)

RAR1, a central player in plant immunity, is targeted by Pseudomonas syringae effector AvrB.

Shang, Li, Cui, He, Thilmony, Chintamanani, Zwiesler-Vollick, Gopalan, Tang, Zhou; (Journal Article)

Seizures and enhanced cortical GABAergic inhibition in two mouse models of human autosomal dominant nocturnal frontal lobe epilepsy.

Klaassen, Glykys, Maguire, Labarca, Mody, Boulter; (JOURNAL ARTICLE)

Notch activity permits retinal cells to progress through multiple progenitor states and acquire a stem cell property.

Jadhav, Cho, Cepko; (Journal Article)


N Engl J Med

The myeloproliferative disorders.

Campbell, Green; (Journal Article, Review)

The value of medical spending in the United States.

Barr; (Comment, Historical Article, Letter)

Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia.

Druker, Guilhot, O'Brien, Gathmann, Kantarjian, Gattermann, Deininger, Silver, Goldman, Stone, Cervantes, Hochhaus, Powell, Gabrilove, Rousselot, Reiffers, Cornelissen, Hughes, Agis, Fischer, Verhoef, Shepherd, Saglio, Gratwohl, Nielsen, Radich, Simonsson, Taylor, Baccarani, So, Letvak, Larson; (Journal Article, Multicenter Study, Randomized Controlled Trial)

Exploring the uses of RNAi--gene knockdown and the Nobel Prize.

Bernards; (Biography, Historical Article, Journal Article)

Klebsiella oxytoca as a causative organism of antibiotic-associated hemorrhagic colitis.

Högenauer, Langner, Beubler, Lippe, Schicho, Gorkiewicz, Krause, Gerstgrasser, Krejs, Hinterleitner; (Journal Article, Research Support, Non-U.S. Gov't)

Treatment of rectal cancer.

Harewood; (Comment, Letter)

Peginterferon and ribavirin for chronic hepatitis C.

Hoofnagle, Seeff; (Journal Article, Review)

Clinical problem-solving. Sum of the parts.

Prasad, Buller, Mena, Sofair; (Case Reports, Journal Article)

Drug-eluting stents in primary PCI.

Alfonso; (Comment, Letter)

Images in clinical medicine. Medical mystery--abnormal abdominal radiograph.

Tajima, Kurabayashi; (Journal Article)

Thiazolidinediones for initial treatment of type 2 diabetes?

Nathan; (Comment, Editorial)

Imatinib mesylate, increased bone formation, and secondary hyperparathyroidism.

Grey, O'Sullivan, Reid, Browett; (Comment, Letter)

Medical mystery: visual-field defect--the answer.

Mathura, Jampol; (Case Reports, Comment, Letter)

Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy.

Kahn, Haffner, Heise, Herman, Holman, Jones, Kravitz, Lachin, O'Neill, Zinman, Viberti; (Comparative Study, Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Another look at imatinib mesylate.

Strebhardt, Ullrich; (Journal Article)

A risk score for predicting death in Chagas' heart disease.

Rocha, Ribeiro; (Comment, Letter)

The ethics and politics of compulsory HPV vaccination.

Colgrove; (Journal Article)


J Natl Cancer Inst

Stat bite: Daily fruit and vegetable consumption.

none; (Journal Article)

Gail model for prediction of absolute risk of invasive breast cancer: independent evaluation in the Florence-European Prospective Investigation Into Cancer and Nutrition cohort.

Decarli, Calza, Masala, Specchia, Palli, Gail; (Journal Article, Research Support, Non-U.S. Gov't)

Population BRCA1 and BRCA2 mutation frequencies and cancer penetrances: a kin-cohort study in Ontario, Canada.

Risch, McLaughlin, Cole, Rosen, Bradley, Fan, Tang, Li, Zhang, Shaw, Narod; (Journal Article, Research Support, N.I.H., Extramural)

CYP3A phenotyping approach to predict systemic exposure to EGFR tyrosine kinase inhibitors.

Li, Karlsson, Brahmer, Spitz, Zhao, Hidalgo, Baker; (Journal Article, Research Support, Non-U.S. Gov't)

p27(Kip1) and cyclin E expression and breast cancer survival after treatment with adjuvant chemotherapy.

Porter, Barlow, Yeh, Lin, Yuan, Donato, Sledge, Shapiro, Ingle, Haskell, Albain, Roberts, Livingston, Hayes; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Conflict-of-interest spurs new rules, not consensus.

Miller; (News)

BRCA mutation frequency and penetrance: new data, old debate.

Offit; (Comment, Editorial, Research Support, Non-U.S. Gov't)

Testing ways to trigger cell death from the outside.

Tuma; (News)

Association of smoking, CpG island methylator phenotype, and V600E BRAF mutations in colon cancer.

Samowitz, Albertsen, Sweeney, Herrick, Caan, Anderson, Wolff, Slattery; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Research groups promoting proton therapy "lite".

Hede; (News)

Re: Childhood leukemia incidence in Britain, 1974-2000: time trends and possible relation to influenza epidemics.

McNally, Eden; (Comment, Letter)

Cellular telephone use and cancer risk: update of a nationwide Danish cohort.

Schüz, Jacobsen, Olsen, Boice, McLaughlin, Johansen; (Journal Article, Research Support, Non-U.S. Gov't)

The risk of cancer risk prediction: "What is my risk of getting breast cancer"?

Elmore, Fletcher; (Comment, Editorial)

New method found to trigger cancer cell suicide.

Garber; (News)

Change in cognitive function after chemotherapy: a prospective longitudinal study in breast cancer patients.

Schagen, Muller, Boogerd, Mellenbergh, van Dam; (Journal Article, Research Support, Non-U.S. Gov't)

Pharmacogenetics of ABCG2 and adverse reactions to gefitinib.

Cusatis, Gregorc, Li, Spreafico, Ingersoll, Verweij, Ludovini, Villa, Hidalgo, Sparreboom, Baker; (Journal Article, Research Support, Non-U.S. Gov't)


Lancet

Mid-level providers: a safe solution for unsafe abortion.

Chong, Mattar; (Comment, Journal Article)

The future of onchocerciasis control in Africa.

Amazigo, Boatin; (Journal Article)

Jaime Sepúlveda: Mexico's passionate proponent of public health.

Boseley; (Biography, News)

Pakistan recognises women's rights.

none; (Editorial)

Global control of sexually transmitted infections.

Low, Broutet, Adu-Sarkodie, Barton, Hossain, Hawkes; (Journal Article)

Sexual and reproductive health: rights and responsibilities.

Shaw; (Journal Article)

Management of severe acute malnutrition in children.

Collins, Dent, Binns, Bahwere, Sadler, Hallam; (Journal Article, Research Support, Non-U.S. Gov't)

Pneumopericardium following rupture of the oesophagus.

Morimatsu, Kawano, Aizawa; (Journal Article)

Chaperonin 10 for rheumatoid arthritis.

Focosi; (Comment, Letter)

Microfinance, intimate-partner violence, and HIV.

none; (Editorial)

Mental health and justice: the case of Andrea Yates.

McLellan; (News)

Improvement of child survival in Mexico: the diagonal approach.

Sepúlveda, Bustreo, Tapia, Rivera, Lozano, Oláiz, Partida, García-García, Valdespino; (Journal Article)

Chaperonin 10 for rheumatoid arthritis - Authors' reply.

Vanags, Williams, Johnson, Feeney; (LETTER)

Inpatient disposition classification for the creation of hospital surge capacity: a multiphase study.

Kelen, Kraus, McCarthy, Bass, Hsu, Li, Scheulen, Shahan, Brill, Green; (Journal Article, Research Support, U.S. Gov't, P.H.S.)

Effect of a structural intervention for the prevention of intimate-partner violence and HIV in rural South Africa: a cluster randomised trial.

Pronyk, Hargreaves, Kim, Morison, Phetla, Watts, Busza, Porter; (Journal Article, Research Support, Non-U.S. Gov't)

Rates of complication in first-trimester manual vacuum aspiration abortion done by doctors and mid-level providers in South Africa and Vietnam: a randomised controlled equivalence trial.

Warriner, Meirik, Hoffman, Morroni, Harries, Huong, Vy, Seuc; (Journal Article, Research Support, Non-U.S. Gov't)

Bringing neurosurgery to life.

none; (Editorial)

Does the world need another AIDS authority?

Obasi, Tovey; (Comment, Letter)

Chaperonin 10 for rheumatoid arthritis.

Kast, Altschuler; (Comment, Letter)

Confessions of a condom lover.

Shelton; (Journal Article)

Persistent left superior vena cava into unroofed coronary sinus.

Piacentini, Saffirio, Marino; (Comment, Letter)

Coma due to meteorism and increased intra-abdominal pressure subsequent to ventriculoperitoneal shunt dysfunction.

Mirzayan, Koenig, Bastuerk, Krauss; (Journal Article)

Reverse triage: useful for day-to-day access block?

Taylor; (Comment, Journal Article)

Digitalis intoxication induced by paroxetine co-administration.

Hallberg, Melhus; (Comment, Letter)

A new discipline is born: comparative health-systems studies.

Horton; (Journal Article)

Sex, politics, and money.

Thomas; (Journal Article)

Digitalis intoxication induced by paroxetine co-administration.

Bateman, Thanacoody, Waring; (Comment, Letter)

War and health in the West Bank and Gaza.

Giacaman; (Comment, Letter)

Does the world need another AIDS authority? - Author's reply.

Billingham; (LETTER)

Does the world need another AIDS authority?

De Cock, Mane; (Comment, Letter)

Promoting protection and pleasure: amplifying the effectiveness of barriers against sexually transmitted infections and pregnancy.

Philpott, Knerr, Maher; (Journal Article, Research Support, Non-U.S. Gov't)

Chaperonin 10 for rheumatoid arthritis.

Okamoto; (Comment, Letter)

Centers for Disease Control and Prevention and authorship.

Birx, Levine; (Comment, Letter)


Expert Rev Mol Diagn

Molecular approaches towards characterization, monitoring and targeting of viral-associated hematological malignancies.

Yin, Jones; (Journal Article)

Recent advances in development of avian flu and influenza diagnostics.

Bourinbaiar, Timofeev, Agwale; (Editorial)

In vivo optical imaging using quantum dots for the management of brain tumors.

Popescu, Toms; (Journal Article)

Biomarkers associated with male infertility are analyzed via a metabolomics platform.

none; (JOURNAL ARTICLE)

Diagnosis of pertussis: a historical review and recent developments.

Wendelboe, Van Rie; (Journal Article)

Dynamics of biological systems: role of systems biology in medical research.

Assmus, Herwig, Cho, Wolkenhauer; (Journal Article, Research Support, Non-U.S. Gov't)

A genetic signature can predict prognosis and response to therapy in breast cancer: Oncotype DX.

Kaklamani; (Journal Article)

Determination of CYP2D6, CYP2C9 and CYP2C19 genotypes with Tag-It mutation detection assays.

Melis, Lyon, McMillin; (Journal Article)

Applications of real-time PCR in the screening of platelet concentrates for bacterial contamination.

Mohammadi, Savelkoul, Pietersz, Reesink; (Journal Article)

European biomarkers summit.

Schweitzer; (Journal Article)

Choline metabolism in cancer: implications for diagnosis and therapy.

Glunde, Jacobs, Bhujwalla; (Journal Article, Research Support, N.I.H., Extramural)

Alternative genotyping method of GSTT1 null/present polymorphism.

Naito, Goto, Ishida, Nishio, Kawai, Hamajima; (Journal Article, Research Support, Non-U.S. Gov't)

Transcriptional profiling of multiple sclerosis: towards improved diagnosis and treatment.

Lindberg, Kappos; (Journal Article)