Nature

Systems biology: Many things from one.

Newman, Weissman; (JOURNAL ARTICLE)

Polo kinase controls cell-cycle-dependent transcription by targeting a coactivator protein.

Darieva, Bulmer, Pic-Taylor, Doris, Geymonat, Sedgwick, Morgan, Sharrocks; (Journal Article)

Robustness-epistasis link shapes the fitness landscape of a randomly drifting protein.

Bershtein, Segal, Bekerman, Tokuriki, Tawfik; (JOURNAL ARTICLE)

Britain plans tough limits to curb emissions.

Hopkin; (Journal Article)

Astrochemistry: Complex organic matter in Titan's aerosols? (Reply).

Israël, Szopa, Raulin, Cabane, Niemann, Atreya, Bauer, Brun, Chassefière, Coll, Condé, Coscia, Hauchecorne, Millian, Nguyen, Owen, Riedler, Samuelson, Siguier, Steller, Sternberg, Vidal-Madjar; (Journal Article)

Insights into social insects from the genome of the honeybee Apis mellifera.

Sequencing Consortium; (Journal Article)

Cell biology: Infectious Alzheimer's disease?

Riek; (Journal Article)

Healthy fats.

Duttaroy; (Journal Article)

Ecology: Spying on nature.

Hopkin; (Journal Article)

Italian government eases in radical reforms.

Abbott; (Journal Article)

Clustered DNA motifs mark X chromosomes for repression by a dosage compensation complex.

McDonel, Jans, Peterson, Meyer; (JOURNAL ARTICLE)

Corrigendum.

none; (Journal Article)

Variability and memory of protein levels in human cells.

Sigal, Milo, Cohen, Geva-Zatorsky, Klein, Liron, Rosenfeld, Danon, Perzov, Alon; (JOURNAL ARTICLE)

Spectroscopy: Molecular motion pictures.

Cho; (Journal Article)

Key contributors.

none; (Journal Article)

Global variation in copy number in the human genome.

Redon, Ishikawa, Fitch, Feuk, Perry, Andrews, Fiegler, Shapero, Carson, Chen, Cho, Dallaire, Freeman, González, Gratacòs, Huang, Kalaitzopoulos, Komura, Macdonald, Marshall, Mei, Montgomery, Nishimura, Okamura, Shen, Somerville, Tchinda, Valsesia, Woodwark, Yang, Zhang, Zerjal, Zhang, Armengol, Conrad, Estivill, Tyler-Smith, Carter, Aburatani, Lee, Jones, Scherer, Hurles; (Journal Article)

The liquidators.

Garrett Farrelly; (Journal Article)

Ecological consequences of major hydrodynamic disturbances on coral reefs.

Madin, Connolly; (JOURNAL ARTICLE)

Astrochemistry: Complex organic matter in Titan's aerosols?

Biemann; (Journal Article)

Eastern Pacific cooling and Atlantic overturning circulation during the last deglaciation.

Kienast, Kienast, Calvert, Eglinton, Mollenhauer, François, Mix; (Journal Article)

A giant leap?

Hansen; (Journal Article)

How Neanderthal molar teeth grew.

Macchiarelli, Bondioli, Debénath, Mazurier, Tournepiche, Birch, Dean; (JOURNAL ARTICLE)

French science after Chirac.

none; (Journal Article)

Magnetic vortex core reversal by excitation with short bursts of an alternating field.

Van Waeyenberge, Puzic, Stoll, Chou, Tyliszczak, Hertel, Fähnle, Brückl, Rott, Reiss, Neudecker, Weiss, Back, Schütz; (Journal Article)

Synaesthesia: The taste of words on the tip of the tongue.

Simner, Ward; (Journal Article)

Snapshot: A night out in the park.

Check; (Journal Article)

Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine.

Bukanov, Smith, Klinger, Ledbetter, Ibraghimov-Beskrovnaya; (JOURNAL ARTICLE)

Slip zone and energetics of a large earthquake from the Taiwan Chelungpu-fault Drilling Project.

Ma, Tanaka, Song, Wang, Hung, Tsai, Mori, Song, Yeh, Soh, Sone, Kuo, Wu; (Journal Article)

Medicine: Blastomeres and stem cells.

Simpson; (Journal Article)

Learning from nature.

Cahn; (Journal Article)

Q&A peter korevaar.

none; (Journal Article)

Opposition to science.

Bradley; (JOURNAL ARTICLE)

Well-being research: A measure of happiness.

Reichhardt; (Journal Article)

Sidelines.

none; (Journal Article)

News in brief.

none; (Journal Article)

Universities urged to do more for poor nations.

Check; (Journal Article)

Human genomics: In search of normality.

Shianna, Willard; (Journal Article)

The science community must unite over Iraq.

Gustafsson; (Journal Article)

A fresh start for Japan.

none; (Journal Article)

p63 protects the female germ line during meiotic arrest.

Suh, Yang, Kettenbach, Bamberger, Michaelis, Zhu, Elvin, Bronson, Crum, McKeon; (JOURNAL ARTICLE)

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice.

O'brien, Pollett, Gallinger, Dick; (JOURNAL ARTICLE)

Science in culture: Burning Bush.

Martin; (Journal Article)

Watching hydrogen-bond dynamics in a beta-turn by transient two-dimensional infrared spectroscopy.

Kolano, Helbing, Kozinski, Sander, Hamm; (Journal Article)

German societies want to keep an international voice.

Gruss; (JOURNAL ARTICLE)

50 & 100 years ago.

none; (Journal Article)

Religious authorities overrule scientists in Iran.

Behnia; (Journal Article)

Anti-evolutionists raise their profile in Europe.

none; (Journal Article)

A bacterial dynamin-like protein.

Low, Löwe; (JOURNAL ARTICLE)

Life in the universal porridge.

Al-Khalili; (Journal Article)

Superconductivity in doped cubic silicon.

Bustarret, Marcenat, Achatz, KaÄmarÄik, LÃ©vy, Huxley, OrtÃ©ga, Bourgeois, Blase, DÃ©barre, Boulmer; (JOURNAL ARTICLE)

Solid-state physics: Super silicon.

Cava; (Journal Article)

Human embryonic stem cell lines derived from single blastomeres.

Klimanskaya, Chung, Becker, Lu, Lanza; (Journal Article)

Dynamics of seismogenic volcanic extrusion at Mount St Helens in 2004-05.

Iverson, Dzurisin, Gardner, Gerlach, Lahusen, Lisowski, Major, Malone, Messerich, Moran, Pallister, Qamar, Schilling, Vallance; (Journal Article)

Imagine projects with a strong emotional appeal.

Osseweijer; (Journal Article)

Correction.

none; (Journal Article)

Aboriginal remains head for home.

Giles; (Journal Article)

Making the paper: Len Pennacchio.

none; (Journal Article)

Tragedy increases woes of US ice fleet.

Dalton; (Journal Article)

One small point.

Marshall; (Journal Article)

Molecular biology: Triggering positive competition.

Yonath; (Journal Article)

Potential of stem-cell-based therapies for heart disease.

Srivastava, Ivey; (Journal Article)

Smiles all round.

none; (Journal Article)

Abstractions.

none; (Journal Article)

Mullite and the mystery of Hessian wares.

Martinón-Torres, Rehren, Freestone; (Journal Article)

Nuclear's core business.

none; (Journal Article)

Research highlights.

none; (Journal Article)

Science in Africa: Conscious of change.

Cherry; (Journal Article)

Identification and expansion of human colon-cancer-initiating cells.

Ricci-Vitiani, Lombardi, Pilozzi, Biffoni, Todaro, Peschle, De Maria; (JOURNAL ARTICLE)

Science

Global warming. U.N. conference puts spotlight on reducing impact of climate change.

Stone, Bohannon; (News)

Abundance distributions imply elevated complexity of post-Paleozoic marine ecosystems.

Wagner, Kosnik, Lidgard; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

A Seafloor Spreading Event Captured by Seismometers.

Tolstoy, Cowen, Baker, Fornari, Rubin, Shank, Waldhauser, Bohnenstiehl, Forsyth, Holmes, Love, Perfit, Weekly, Soule, Glazer; (JOURNAL ARTICLE)

Two Dobzhansky-Muller genes interact to cause hybrid lethality in Drosophila.

Brideau, Flores, Wang, Maheshwari, Wang, Barbash; (Journal Article, Research Support, N.I.H., Extramural)

Effective enforcement in a conservation area.

Hilborn, Arcese, Borner, Hando, Hopcraft, Loibooki, Mduma, Sinclair; (Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Comment on papers by Chong et al., Nishio et al., and Suri et al. on diabetes reversal in NOD mice.

Faustman, Tran, Kodama, Lodde, Szalayova, Key, Toth, Mezey; (Comment, Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Evolutionary history of Salmonella typhi.

Roumagnac, Weill, Dolecek, Baker, Brisse, Chinh, Le, Acosta, Farrar, Dougan, Achtman; (Journal Article, Research Support, Non-U.S. Gov't)

U.S. science policy. Resignations rock Census Bureau.

Holden; (News)

What is natural? The need for a long-term perspective in biodiversity conservation.

Willis, Birks; (Journal Article)

Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice.

McDearmon, Patel, Ko, Walisser, Schook, Chong, Wilsbacher, Song, Hong, Bradfield, Takahashi; (Journal Article, Research Support, N.I.H., Extramural)

A post-perovskite lens and D'' heat flux beneath the central Pacific.

Lay, Hernlund, Garnero, Thorne; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Hervé this profile. The joy of evidence-based cooking.

Enserink; (News)

A bacterial protein enhances the release and efficacy of liposomal cancer drugs.

Cheong, Huang, Bettegowda, Diaz, Kinzler, Zhou, Vogelstein; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Distinct Fermi-Momentum-Dependent Energy Gaps in Deeply Underdoped Bi2212.

Tanaka, Lee, Lu, Fujimori, Fujii, Risdiana, Terasaki, Scalapino, Devereaux, Hussain, Shen; (JOURNAL ARTICLE)

Distinct Populations of Primary and Secondary Effectors During RNAi in C. elegans.

Pak, Fire; (JOURNAL ARTICLE)

Plants, RNAi, and the Nobel Prize.

Jorgensen; (Comment, Letter)

Mentoring. Volunteers bring passion to science outreach.

Beck, Morgan, Strand, Woolsey; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Plant science. Distributing nutrition.

Gitlin; (Comment, Journal Article)

Chinese gene therapy. Gendicine's efficacy: hard to translate.

Xin; (News)

Formation of a Nematic Fluid at High Fields in Sr3Ru2O7.

Borzi, Grigera, Farrell, Perry, Lister, Lee, Tennant, Maeno, Mackenzie; (JOURNAL ARTICLE)

Physics. Superconductivity with a twist.

Rice; (Comment, Journal Article)

Structural Basis for Ribosome Recruitment and Manipulation by a Viral IRES RNA.

Pfingsten, Costantino, Kieft; (JOURNAL ARTICLE)

Sherwood Boehlert interview. Explaining science to power: make it simple, make it pay. Interview by Jeffrey Mervis.

Boehlert; (Interview, News)

Fusion. Scientists reap ITER's first dividends.

Clery; (News)

Paleoecology. Life's complexity cast in stone.

Kiessling; (Comment, Journal Article)

A nonprotein amino acid and neurodegeneration.

Cox, Banack; (Comment, Letter)

Predictive codes for forthcoming perception in the frontal cortex.

Summerfield, Egner, Greene, Koechlin, Mangels, Hirsch; (Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)

Evolution. Two rapidly evolving genes spell trouble for hybrids.

Pennisi; (Comment, News)

U.S. intellectual property law. Government questions sequencing patent.

Kintisch; (News)

Neuroscience. The brain's dark energy.

Raichle; (Journal Article)

Atmosphere. Global change in the upper atmosphere.

Lastovicka, Akmaev, Beig, Bremer, Emmert; (Journal Article)

Science funding. Italy's research crunch: election promises fade.

Biggin; (News)

A NAC Gene regulating senescence improves grain protein, zinc, and iron content in wheat.

Uauy, Distelfeld, Fahima, Blechl, Dubcovsky; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Carbon trading.

Schlesinger; (Editorial)

A debate over Iraqi death estimates.

Burnham, Roberts; (Comment, Letter)

Chinese gene therapy. Splicing out the West?

Guo, Xin; (News)

U.S. intellectual property. Patent experts hope high court will clarify what's obvious.

Kintisch; (News)

Ongoing buildup of refractory organic carbon in boreal soils during the Holocene.

Smittenberg, Eglinton, Schouten, Damsté; (Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Developmental biology. Teams identify cardiac 'stem cell'.

Couzin; (News)

Nature Methods

QUICKstep and GS-TAP: new moves for protein-interaction analysis.

Braun, Cusick, Vidal; (Journal Article)

Single protein complex visualization: Seeing is believing.

Lievens, Tavernier; (Journal Article)

Infrared-LAMP: two-photon uncaging and imaging of gap junctional communication in three dimensions.

Dakin, Li; (Journal Article)

G protein-coupled receptors: too many dimers?

Lohse; (Journal Article)

The inside tag.

Kaganman; (Journal Article)

Atomic force microscopy of membrane proteins separating two aqueous compartments.

Dufrêne; (Journal Article)

Sensitive and specific method for detecting G protein-coupled receptor mRNAs.

Hansen, Chen, Inman, Phan, Qi, Xiang, Palkovits, Cherman, Kuznetsov, Robey, Mezey, Brownstein; (JOURNAL ARTICLE)

Rational design of a super core promoter that enhances gene expression.

Juven-Gershon, Cheng, Kadonaga; (Journal Article, Research Support, N.I.H., Extramural)

Bacteria make the rotor go round.

Doerr; (Journal Article)

siRNAs meet their match.

Potash; (Journal Article)

Protein complex expression by using multigene baculoviral vectors.

Fitzgerald, Berger, Schaffitzel, Yamada, Richmond, Berger; (Journal Article)

Complementary methods for studies of protein interactions in living cells.

Kerppola; (Journal Article)

Story of C's.

Kiermer; (Journal Article)

Sweetening up yeast glycoprotein synthesis.

Doerr; (Journal Article)

Thinking outside the dish.

Eisenstein; (Journal Article)

A protein alternative to RNAi.

Evanko; (Journal Article)

Nothing to declare?

none; (Editorial)

Nature Biotechnology

Blue fluorescent proteins with enhanced brightness and photostability from a structurally targeted library.

Mena, Treynor, Mayo, Daugherty; (JOURNAL ARTICLE)

The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT.

Bettegowda, Huang, Lin, Cheong, Kohli, Szabo, Zhang, Diaz, Velculescu, Parmigiani, Kinzler, Vogelstein, Zhou; (JOURNAL ARTICLE)

Exit strategies in Europe.

Buckel, Dauer, Frei, Nothias; (Journal Article)

Nature Medicine

Comprehensive volumetric optical microscopy in vivo.

Yun, Tearney, Vakoc, Shishkov, Oh, Desjardins, Suter, Chan, Evans, Jang, Nishioka, de Boer, Bouma; (JOURNAL ARTICLE)

Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells.

Mavilio, Pellegrini, Ferrari, Di Nunzio, Di Iorio, Recchia, Maruggi, Ferrari, Provasi, Bonini, Capurro, Conti, Magnoni, Giannetti, De Luca; (JOURNAL ARTICLE)

Microbial translocation is a cause of systemic immune activation in chronic HIV infection.

Brenchley, Price, Schacker, Asher, Silvestri, Rao, Kazzaz, Bornstein, Lambotte, Altmann, Blazar, Rodriguez, Teixeira-Johnson, Landay, Martin, Hecht, Picker, Lederman, Deeks, Douek; (JOURNAL ARTICLE)

Activation of beta(2)-adrenergic receptor stimulates gamma-secretase activity and accelerates amyloid plaque formation.

Ni, Zhao, Bao, Zou, Teng, Wang, Song, Xiong, Bai, Pei; (JOURNAL ARTICLE)

Nature Genetics

Automating resequencing-based detection of insertion-deletion polymorphisms.

Bhangale, Stephens, Nickerson; (JOURNAL ARTICLE)

In germ cells of mouse embryonic ovaries, the decision to enter meiosis precedes premeiotic DNA replication.

Baltus, Menke, Hu, Goodheart, Carpenter, de Rooij, Page; (JOURNAL ARTICLE)

Genome assembly comparison identifies structural variants in the human genome.

Khaja, Zhang, Macdonald, He, Joseph-George, Wei, Rafiq, Qian, Shago, Pantano, Aburatani, Jones, Redon, Hurles, Armengol, Estivill, Mural, Lee, Scherer, Feuk; (JOURNAL ARTICLE)

Conservation of hotspots for recombination in low-copy repeats associated with the NF1 microdeletion.

Raedt, Stephens, Heyns, Brems, Thijs, Messiaen, Stephens, Lazaro, Wimmer, Kehrer-Sawatzki, Vidaud, Kluwe, Marynen, Legius; (JOURNAL ARTICLE)

Molecular Medicine

Proteomics

Proteomic analysis of log to stationary growth phase Lactobacillus plantarum cells and a 2-DE database.

Cohen, Renes, Bouwman, Zoetendal, Mariman, de Vos, Vaughan; (JOURNAL ARTICLE)

Establishing a liquid-phase IEF in combination with 2-DE for the analysis of Leishmania proteins.

Brobey, Soong; (JOURNAL ARTICLE)

An investigation of the effects of endometriosis on the proteome of human eutopic endometrium: A heterogeneous tissue with a complex disease.

Fowler, Tattum, Bhattacharya, Klonisch, Hombach-Klonisch, Gazvani, Lea, Miller, Simpson, Cash; (JOURNAL ARTICLE)

Nature Drug Discovery

BMC Bioinformatics

A scalable machine-learning approach to recognize chemical names within large text databases.

Wren; (JOURNAL ARTICLE)

Independent Component Analysis-motivated Approach to Classificatory Decomposition of Cortical Evoked Potentials.

Smolinski, Buchanan, Boratyn, Milanova, Prinz; (JOURNAL ARTICLE)

Systematic assignment of thermodynamic constraints in metabolic networks models.

Kummel, Panke, Heinemann; (JOURNAL ARTICLE)

Improvement in the Reproducibility and Accuracy of DNA Microarray Quantification by Optimizing Hybridization Conditions.

Han, Melvin, Shi, Branham, Moland, Pine, Thompson, Fuscoe; (JOURNAL ARTICLE)

EGenBio: A Data Management System for Evolutionary Genomics and Biodiversity.

Nahum, Reynolds, Wang, Faith, Jonna, Jiang, Meyer, Pollock; (JOURNAL ARTICLE)

Permutation test for periodicity in short time series data.

Ptitsyn, Zvonic, Gimble; (JOURNAL ARTICLE)

Microarray analysis distinguishes differential gene expression patterns from large and small colony Thymidine kinase mutants of L5178Y mouse lymphoma cells.

Han, Wang, Tong, Moore, Fuscoe, Chen; (JOURNAL ARTICLE)

Improving the Performance of SVM-RFE to Select Genes in Microarray Data.

Ding, Wilkins; (JOURNAL ARTICLE)

Support Vector Machine Implementations for Classification & Clustering.

Winters-Hilt, Yelundur, McChesney, Landry; (JOURNAL ARTICLE)

GOFFA: Gene Ontology For Functional Analysis - A FDA Gene Ontology Tool for Analysis of Genomic and Proteomic Data.

Sun, Fang, Chen, Perkins, Tong; (JOURNAL ARTICLE)

Novel methods for secondary structure determination using low wavelength (VUV) circular dichroism spectroscopic data.

Lees, Miles, Janes, Wallace; (JOURNAL ARTICLE)

Hidden Markov Model Variants and their Application.

Winters-Hilt; (JOURNAL ARTICLE)

Statistical analysis of an RNA titration series evaluates microarray precision and sensitivity on a whole-array basis.

Holloway, Oshlack, Diyagama, Bowtell, Smyth; (JOURNAL ARTICLE)

Metric for Measuring the Effectiveness of Clustering of DNA Microarray Expression.

Loganantharaj, Cheepala, Clifford; (JOURNAL ARTICLE)

DNA Molecule Classification Using Feature Primitives.

Iqbal, Landry, Winters-Hilt; (JOURNAL ARTICLE)

An Automated Method for Rapid Identification of Putative Gene Family Members in Plants.

Frank, Mane, Ercal; (JOURNAL ARTICLE)

Connectivity Independent Protein Fold Detection: a Hierarchical Approach.

Kolbeck, May, Schmidt-Goenner, Steinke, Knapp; (JOURNAL ARTICLE)

A Fourier Transformation based Method to Mine Peptide Space for Antimicrobial Activity.

Nagarajan, Kaushik, Murali, Zhang, Lakhera, Elasri, Deng; (JOURNAL ARTICLE)

Nanopore Detector based analysis of single-molecule conformational kinetics and binding interactions.

Winters-Hilt; (JOURNAL ARTICLE)

Proceedings of the Third Annual Conference of the MidSouth Computational Biology and Bioinformatics Society.

Wren, Gusev, Ptitsyn, Winters-Hilt; (JOURNAL ARTICLE)

Analysis of gene expression changes in relation to toxicity and tumorigenesis in the livers of Big Blue transgenic rats fed comfrey (Symphytum officinale).

Mei, Guo, Zhang, Shi, Sun, Fung, Moland, Dial, Fuscoe, Chen; (JOURNAL ARTICLE)

Gene Expression Profiles Distinguish the Carcinogenic Effects of Aristolochic Acid in Target (Kidney) and Non-target (Liver) Tissues in Rats.

Chen, Guo, Zhang, Shi, Fang, Sun, Fuscoe, Mei; (JOURNAL ARTICLE)

Beyond microarrays: Finding key transcription factors controlling signal transduction pathways.

Kel, Voss, Jauregui, Kel-Margoulis, Wingender; (JOURNAL ARTICLE)

IntNetDB v1.0: An integrated protein-protein interaction network database generated by a probabilistic model.

Xia, Dong, Han; (JOURNAL ARTICLE)

Cheminformatics methods for novel nanopore analysis of HIV DNA termini.

Winters-Hilt, Landry, Akeson, Tanase, Amin, Coombs, Morales, Millet, Baribault, Sendamangalam; (JOURNAL ARTICLE)

A method for computing the overall statistical significance of a treatment effect among a group of genes.

Delongchamp, Lee, Velasco; (JOURNAL ARTICLE)

RiboaptDB: A Comprehensive Database of Ribozymes and Aptamers.

Thodima, Pirooznia, Deng; (JOURNAL ARTICLE)

JUICE: a data management system that facilitates the analysis of large volumes of information in an EST project workflow.

Latorre, Silva, Saba, Guziolowski, Vizoso, Martinez, Maldonado, Morales, Caroca, Cambiazo, Campos-Vargas, Gonzalez, Orellana, Retamales, Meisel; (JOURNAL ARTICLE)

CoXpress: differential co-expression in gene expression data.

Watson; (Journal Article, Research Support, Non-U.S. Gov't)

Differential gene expression in mouse primary hepatocytes exposed to the peroxisome proliferator-activated receptor alpha agonists.

Guo, Fang, Collins, Fan, Dial, Wong, Mehta, Blann, Shi, Tong, Dragan; (JOURNAL ARTICLE)

Bioinformatics

Qualitatively modelling and analysing genetic regulatory networks: a Petri net approach.

Steggles, Banks, Shaw, Wipat; (JOURNAL ARTICLE)

PrepMS: TOF MS data graphical preprocessing tool.

Karpievitch, Hill, Smolka, Morris, Coombes, Baggerly, Almeida; (JOURNAL ARTICLE)

WHAP: haplotype-based association analysis.

Purcell, Daly, Sham; (JOURNAL ARTICLE)

A predictive model for identifying proteins by a single peptide match.

Higdon, Kolker; (JOURNAL ARTICLE)

ARIA2: automated NOE assignment and data integration in NMR structure calculation.

Rieping, Habeck, Bardiaux, Bernard, Malliavin, Nilges; (JOURNAL ARTICLE)

NvMap: automated analysis of NMR chemical shift perturbation data.

Fukui, Chen; (JOURNAL ARTICLE)

ProteomeCommons.org IO Framework: reading and writing multiple proteomics data formats.

Falkner, Falkner, Andrews; (JOURNAL ARTICLE)

A framework for gene expression analysis.

Schreiber, Baumann; (JOURNAL ARTICLE)

PartTree: an algorithm to build an approximate tree from a large number of unaligned sequences.

Katoh, Toh; (JOURNAL ARTICLE)

SNP2NMD: a database of human SNPs (single nucleotide polymorphisms) causing NMD (nonsense-mediated mRNA decay).

Han, Kim, Park; (JOURNAL ARTICLE)

QOMA: Quasi-Optimal Multiple Alignment of protein sequences.

Zhang, Kahveci; (JOURNAL ARTICLE)

Proc Natl Acad Sci U S A

Multiple independent origins of sex chromosomes in amniotes.

Vallender, Lahn; (JOURNAL ARTICLE)

Dendritic compartmentalization of chloride cotransporters underlies directional responses of starburst amacrine cells in retina.

Gavrikov, Nilson, Dmitriev, Zucker, Mangel; (JOURNAL ARTICLE)

NMDA receptor surface mobility depends on NR2A-2B subunits.

Groc, Heine, Cousins, Stephenson, Lounis, Cognet, Choquet; (JOURNAL ARTICLE)

Random mutations, selected mutations: A PIN opens the door to new genetic landscapes.

Klein; (JOURNAL ARTICLE)

Opposing forces of aerosol cooling and El Nino drive coral bleaching on Caribbean reefs.

Gill, Watkinson, McWilliams, Côté; (JOURNAL ARTICLE)

Exploring atomistic details of pH-dependent peptide folding.

Khandogin, Chen, Brooks; (JOURNAL ARTICLE)

Laser trapping in anisotropic fluids and polarization-controlled particle dynamics.

Smalyukh, Kachynski, Kuzmin, Prasad; (JOURNAL ARTICLE)

FAPP2, cilium formation, and compartmentalization of the apical membrane in polarized Madin-Darby canine kidney (MDCK) cells.

Vieira, Gaus, Verkade, Fullekrug, Vaz, Simons; (JOURNAL ARTICLE)

Divergent activities of an engineered antibody in murine and human systems have implications for therapeutic antibodies.

Vaccaro, Bawdon, Wanjie, Ober, Ward; (JOURNAL ARTICLE)

Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death.

Yu, Andrabi, Wang, Kim, Poirier, Dawson, Dawson; (JOURNAL ARTICLE)

The dynamics behind Titan's methane clouds.

Mitchell, Pierrehumbert, Frierson, Caballero; (JOURNAL ARTICLE)

Relative blindsight in normal observers and the neural correlate of visual consciousness.

Lau, Passingham; (JOURNAL ARTICLE)

Rapid and reversible changes in intrahippocampal connectivity during the course of hibernation in European hamsters.

Magariños, McEwen, Saboureau, Pevet; (JOURNAL ARTICLE)

Genomic analysis of the uncultivated marine crenarchaeote Cenarchaeum symbiosum.

Hallam, Konstantinidis, Putnam, Schleper, Watanabe, Sugahara, Preston, de la Torre, Richardson, Delong; (JOURNAL ARTICLE)

Participation of mouse DNA polymerase {iota} in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer.

Dumstorf, Clark, Lin, Kissling, Yuan, Kucherlapati, McGregor, Kunkel; (JOURNAL ARTICLE)

Ameiotic recombination in asexual lineages of Daphnia.

Omilian, Cristescu, Dudycha, Lynch; (JOURNAL ARTICLE)

Bone morphogenetic protein signaling regulates the size of hair follicles and modulates the expression of cell cycle-associated genes.

Sharov, Sharova, Mardaryev, di Vignano, Atoyan, Weiner, Yang, Brissette, Dotto, Botchkarev; (JOURNAL ARTICLE)

High-resolution in situ x-ray study of the hydrophobic gap at the water-octadecyl-trichlorosilane interface.

Mezger, Reichert, Schöder, Okasinski, Schröder, Dosch, Palms, Ralston, Honkimäki; (JOURNAL ARTICLE)

Ligation of the cell surface receptor, CD46, alters T cell polarity and response to antigen presentation.

Oliaro, Pasam, Waterhouse, Browne, Ludford-Menting, Trapani, Russell; (JOURNAL ARTICLE)

Polymeric triple-shape materials.

Bellin, Kelch, Langer, Lendlein; (JOURNAL ARTICLE)

Crystal structure of HIV-1 protease in situ product complex and observation of a low-barrier hydrogen bond between catalytic aspartates.

Das, Prashar, Mahale, Serre, Ferrer, Hosur; (JOURNAL ARTICLE)

Active retrotransposition by a synthetic L1 element in mice.

An, Han, Wheelan, Davis, Coombes, Ye, Triplett, Boeke; (JOURNAL ARTICLE)

Autoantibody-mediated demyelination depends on complement activation but not activatory Fc-receptors.

Urich, Gutcher, Prinz, Becher; (JOURNAL ARTICLE)

Mitochondrial deoxynucleotide pool sizes in mouse liver and evidence for a transport mechanism for thymidine monophosphate.

Ferraro, Nicolosi, Bernardi, Reichard, Bianchi; (JOURNAL ARTICLE)

Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men.

Petersen, Dufour, Feng, Befroy, Dziura, Man, Cobelli, Shulman; (JOURNAL ARTICLE)

Mst3b, a purine-sensitive Ste20-like protein kinase, regulates axon outgrowth.

Irwin, Li, O'toole, Benowitz; (JOURNAL ARTICLE)

Charting uncertainty about ant origins.

Crozier; (JOURNAL ARTICLE)

Suppression of spontaneous genome rearrangements in yeast DNA helicase mutants.

Schmidt, Kolodner; (JOURNAL ARTICLE)

Acetylation of MEK2 and I{kappa}B kinase (IKK) activation loop residues by YopJ inhibits signaling.

Mittal, Peak-Chew, McMahon; (JOURNAL ARTICLE)

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth.

Palomero, Lim, Odom, Sulis, Real, Margolin, Barnes, O'neil, Neuberg, Weng, Aster, Sigaux, Soulier, Look, Young, Califano, Ferrando; (JOURNAL ARTICLE)

Speech perception problems of the hearing impaired reflect inability to use temporal fine structure.

Lorenzi, Gilbert, Carn, Garnier, Moore; (JOURNAL ARTICLE)

Global modulation of chromatin dynamics mediated by dephosphorylation of linker histone H1 is necessary for erythroid differentiation.

Yellajoshyula, Brown; (JOURNAL ARTICLE)

Continuous tooth generation in mouse is induced by activated epithelial Wnt/{beta}-catenin signaling.

Järvinen, Salazar-Ciudad, Birchmeier, Taketo, Jernvall, Thesleff; (JOURNAL ARTICLE)

Prolyl hydroxylase-1 negatively regulates I{kappa}B kinase-{beta}, giving insight into hypoxia-induced NF{kappa}B activity.

Cummins, Berra, Comerford, Ginouves, Fitzgerald, Seeballuck, Godson, Nielsen, Moynagh, Pouyssegur, Taylor; (JOURNAL ARTICLE)

Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology.

Jeyaraju, Xu, Letellier, Bandaru, Zunino, Berg, McBride, Pellegrini; (JOURNAL ARTICLE)

A Legionella pneumophila-translocated substrate that is required for growth within macrophages and protection from host cell death.

Laguna, Creasey, Li, Valtz, Isberg; (JOURNAL ARTICLE)

Activation of an oncogenic microRNA cistron by provirus integration.

Wang, Wang, Bartha, Li, Channa, Klinger, Killeen, Wabl; (JOURNAL ARTICLE)

Influence of dominant HIV-1 epitopes on HLA-A3/peptide complex formation.

Racape, Connan, Hoebeke, Choppin, Guillet; (JOURNAL ARTICLE)

Poly(ADP-ribose) (PAR) polymer is a death signal.

Andrabi, Kim, Yu, Wang, Koh, Sasaki, Klaus, Otsuka, Zhang, Koehler, Hurn, Poirier, Dawson, Dawson; (JOURNAL ARTICLE)

Characterization of a cancer/testis (CT) antigen gene family capable of eliciting humoral response in cancer patients.

Parmigiani, Bettoni, Vibranovski, Lopes, Martins, Cunha, Soares, Simpson, de Souza, Camargo; (JOURNAL ARTICLE)

Paclitaxel induces calcium oscillations via an inositol 1,4,5-trisphosphate receptor and neuronal calcium sensor 1-dependent mechanism.

Boehmerle, Splittgerber, Lazarus, McKenzie, Johnston, Austin, Ehrlich; (JOURNAL ARTICLE)

A critical role for TNF receptor-associated factor 1 and Bim down-regulation in CD8 memory T cell survival.

Sabbagh, Srokowski, Pulle, Snell, Sedgmen, Liu, Tsitsikov, Watts; (JOURNAL ARTICLE)

Reconstructing repressor protein levels from expression of gene targets in Escherichia coli.

Khanin, Vinciotti, Wit; (JOURNAL ARTICLE)

Multiple valence superatoms.

Reveles, Khanna, Roach, Castleman; (JOURNAL ARTICLE)

Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function.

Chou, Elledge; (JOURNAL ARTICLE)

Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules.

Leung, Calabrese, Sharp; (JOURNAL ARTICLE)

Elucidation of the function of type 1 human methionine aminopeptidase during cell cycle progression.

Hu, Addlagatta, Lu, Matthews, Liu; (JOURNAL ARTICLE)

Photoinduced electron flow in a self-assembling supramolecular extension cable.

Ferrer, Rogez, Credi, Ballardini, Gandolfi, Balzani, Liu, Tseng, Stoddart; (JOURNAL ARTICLE)

Characterization of a core binding site for ADAMTS-13 in the A2 domain of von Willebrand factor.

Wu, Fujikawa, McMullen, Chung; (JOURNAL ARTICLE)

Crystal structure of {pi} initiator protein-iteron complex of plasmid R6K: Implications for initiation of plasmid DNA replication.

Swan, Bastia, Davies; (JOURNAL ARTICLE)

Two isoforms of tissue transglutaminase mediate opposing cellular fates.

Antonyak, Jansen, Miller, Ly, Endo, Cerione; (JOURNAL ARTICLE)

Using cryo-EM to measure the dipole potential of a lipid membrane.

Wang, Bose, Sigworth; (JOURNAL ARTICLE)

Direct observation of DNA bending/unbending kinetics in complex with DNA-bending protein IHF.

Kuznetsov, Sugimura, Vivas, Crothers, Ansari; (JOURNAL ARTICLE)

Costs and benefits of processivity in enzymatic degradation of recalcitrant polysaccharides.

Horn, Sikorski, Cederkvist, Vaaje-Kolstad, Sørlie, Synstad, Vriend, Vårum, Eijsink; (JOURNAL ARTICLE)

The root endophytic fungus Piriformospora indica requires host cell death for proliferation during mutualistic symbiosis with barley.

Deshmukh, Hückelhoven, Schäfer, Imani, Sharma, Weiss, Waller, Kogel; (JOURNAL ARTICLE)

Direct peptide-regulatable interactions between MHC class I molecules and tapasin.

Rizvi, Raghavan; (JOURNAL ARTICLE)

Quantifying the relation between adhesion ligand-receptor bond formation and cell phenotype.

Kong, Boontheekul, Mooney; (JOURNAL ARTICLE)

Predicted seminal astacin-like protease is required for processing of reproductive proteins in Drosophila melanogaster.

Ravi Ram, Sirot, Wolfner; (JOURNAL ARTICLE)

The gatekeeper residue controls autoactivation of ERK2 via a pathway of intramolecular connectivity.

Emrick, Lee, Starkey, Mumby, Resing, Ahn; (JOURNAL ARTICLE)

A structural model reveals energy transduction in dynein.

Serohijos, Chen, Ding, Elston, Dokholyan; (JOURNAL ARTICLE)

Power spectra reveal the influence of stochasticity on nonlinear population dynamics.

Reuman, Desharnais, Costantino, Ahmad, Cohen; (JOURNAL ARTICLE)

Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion.

Zhu, Jankovic, Grinberg, Guo, Paul; (JOURNAL ARTICLE)

Blocking the apolipoprotein E/amyloid-{beta} interaction as a potential therapeutic approach for Alzheimer's disease.

Sadowski, Pankiewicz, Scholtzova, Mehta, Prelli, Quartermain, Wisniewski; (JOURNAL ARTICLE)

A physical linkage between cystic fibrosis airway surface dehydration and Pseudomonas aeruginosa biofilms.

Matsui, Wagner, Hill, Schwab, Rogers, Button, Taylor, Superfine, Rubinstein, Iglewski, Boucher; (JOURNAL ARTICLE)

Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression.

Sun, He, Qing, Zhou, Dobie, Cai, Staufenbiel, Huang, Song; (JOURNAL ARTICLE)

PKB and megalin determine the survival or death of renal proximal tubule cells.

Caruso-Neves, Pinheiro, Cai, Souza-Menezes, Guggino; (JOURNAL ARTICLE)

Bone marrow-derived fibroblast precursors mediate ischemic cardiomyopathy in mice.

Haudek, Xia, Huebener, Lee, Carlson, Crawford, Pilling, Gomer, Trial, Frangogiannis, Entman; (JOURNAL ARTICLE)

A two-step mechanism underlies the planar polarization of regenerating sensory hair cells.

López-Schier, Hudspeth; (JOURNAL ARTICLE)

Testosterone increases bioavailability of carotenoids: Insights into the honesty of sexual signaling.

Blas, Pérez-Rodríguez, Bortolotti, Viñuela, Marchant; (JOURNAL ARTICLE)

Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease.

Ries, Henchcliffe, Kareva, Rzhetskaya, Bland, During, Kholodilov, Burke; (JOURNAL ARTICLE)

Effect of urea on the structural dynamics of water.

Rezus, Bakker; (JOURNAL ARTICLE)

A second isoform of the ferredoxin:NADP oxidoreductase generated by an in-frame initiation of translation.

Thomas, Ughy, Lagoutte, Ajlani; (JOURNAL ARTICLE)

Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4.

Mari, Florea, Persengiev, Verkaik, Brüggenwirth, Modesti, Giglia-Mari, Bezstarosti, Demmers, Luider, Houtsmuller, van Gent; (JOURNAL ARTICLE)

Stepwise binding and bending of DNA by Escherichia coli integration host factor.

Sugimura, Crothers; (JOURNAL ARTICLE)

A different function for a member of an ancient and highly conserved cytochrome P450 family: From essential sterols to plant defense.

Qi, Bakht, Qin, Leggett, Hemmings, Mellon, Eagles, Werck-Reichhart, Schaller, Lesot, Melton, Osbourn; (JOURNAL ARTICLE)

Inference for nonlinear dynamical systems.

Ionides, Bretó, King; (JOURNAL ARTICLE)

The promyelocytic leukemia protein functions as a negative regulator of IFN-{gamma} signaling.

Choi, Bernardi, Pandolfi, Benveniste; (JOURNAL ARTICLE)

Charge transfer through DNA nanoscaled assembly programmable with DNA building blocks.

Osakada, Kawai, Fujitsuka, Majima; (JOURNAL ARTICLE)

N Engl J Med

H5N1 Influenza -- Continuing Evolution and Spread.

Webster, Govorkova; (Journal Article)

Asymptomatic coronary-artery spasm.

Hamon, Hamon; (Journal Article)

Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis.

Minisola, Scillitani, Romagnoli; (Comment, Letter)

Observational Studies of Drug Safety -- Aprotinin and the Absence of Transparency.

Hiatt; (JOURNAL ARTICLE)

Stress, aging, and neurodegenerative disease.

Morimoto; (Journal Article)

Termination of Resuscitation in Out-of-Hospital Cardiac Arrest.

Böttiger, Popp, Teschendorf, Hauswald, Ajani, Waksman, Mayer, Li, Morrissey, O'connor, During, Morrison, Kiss, Verbeek; (JOURNAL ARTICLE)

Therapy for methicillin-resistant Staphylococcus aureus.

Jetton; (Comment, Letter)

Therapy for methicillin-resistant Staphylococcus aureus.

Torres-Tortosa, Caballero-Granado, Canueto; (Comment, Letter)

Deep-brain stimulation for Parkinson's disease.

Lieb, Schlaepfer, Deuschl, Volkmann; (Journal Article)

Three Indonesian Clusters of H5N1 Virus Infection in 2005.

Kandun, Wibisono, Sedyaningsih, Yusharmen, Hadisoedarsuno, Purba, Santoso, Septiawati, Tresnaningsih, Heriyanto, Yuwono, Harun, Soeroso, Giriputra, Blair, Jeremijenko, Kosasih, Putnam, Samaan, Silitonga, Chan, Poon, Lim, Klimov, Lindstrom, Guan, Donis, Katz, Cox, Peiris, Uyeki; (JOURNAL ARTICLE)

Bivalirudin for Patients with Acute Coronary Syndromes.

Stone, McLaurin, Cox, Bertrand, Lincoff, Moses, White, Pocock, Ware, Feit, Colombo, Aylward, Cequier, Darius, Desmet, Ebrahimi, Hamon, Rasmussen, Rupprecht, Hoekstra, Mehran, Ohman; (JOURNAL ARTICLE)

Squamous-cell carcinoma with pericardial metastases.

Boukhalil, Debek; (Journal Article)

Research replication.

Drazen; (Journal Article)

Judging the safety of aprotinin.

Mangano, Rieves, Weiss; (Journal Article)

Educational strategies to promote clinical diagnostic reasoning.

Bowen; (Journal Article)

Dangerous deception -- hiding the evidence of adverse drug effects.

Avorn; (Journal Article)

Accounting for ACUITY.

Bittl; (Journal Article)

The asthma epidemic.

Eder, Ege, von Mutius; (Journal Article)

Obstetricians Still Await a Deus ex Machina.

Greene; (Journal Article)

Telithromycin and acute liver failure.

Graham; (Journal Article)

Building on experience -- the development of clinical reasoning.

Norman; (Journal Article)

Case 36-2006 -- A 35-Year-Old Pregnant Woman with New Hypertension.

Klibanski, Stephen, Greene, Blake, Wu; (JOURNAL ARTICLE)

Avian Influenza A (H5N1) Infection in Eastern Turkey in 2006.

Oner, Bay, Arslan, Akdeniz, Sahin, Cesur, Epcacan, Yilmaz, Deger, Kizilyildiz, Karsen, Ceyhan; (Journal Article)

Fetal Pulse Oximetry and Cesarean Delivery.

Bloom, Spong, Thom, Varner, Rouse, Weininger, Ramin, Caritis, Peaceman, Sorokin, Sciscione, Carpenter, Mercer, Thorp, Malone, Harper, Iams, Anderson; (JOURNAL ARTICLE)

J Natl Cancer Inst

Lancet

Preventing unintended pregnancy: let us count the ways.

Trussell, Raymond; (Comment, Journal Article)

Mortality in patients with hepatitis B or hepatitis C.

Völzke; (Comment, Letter)

Chagas' disease in Mexico.

Attaran; (Comment, Letter)

Health reform in Mexico: a work in progress.

Fineberg; (Journal Article)

Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.

Cannon, Curtis, FitzGerald, Krum, Kaur, Bolognese, Reicin, Bombardier, Weinblatt, van der Heijde, Erdmann, Laine; (Journal Article, Research Support, Non-U.S. Gov't )

Influenza vaccination for elderly people and their care workers.

Smith, Shay; (Journal Article)

Chagas' disease in Mexico - Response from the Mexican Ministry of Health.

Conyer; (Letter)

The evolving doctor.

Horton, Gilmore; (Journal Article)

Diagnosis and prevention of pertussis - Authors' reply.

Fry, Crowcroft, Pebody; (Letter)

Mortality in patients with hepatitis B or hepatitis C - Authors' reply.

Amin, Law, Dore; (Letter)

Diagnosis and prevention of pertussis.

Preston; (Comment, Letter)