Nature

Transiting extrasolar planetary candidates in the Galactic bulge.

Sahu, Casertano, Bond, Valenti, Smith, Minniti, Zoccali, Livio, Panagia, Piskunov, Brown, Brown, Renzini, Rich, Clarkson, Lubow; (Journal Article)

Bench-to-bedside solution to funding problems.

Bakhoum; (Comment, Letter)

Sexual reproduction selects for robustness and negative epistasis in artificial gene networks.

Azevedo, Lohaus, Srinivasan, Dang, Burch; (JOURNAL ARTICLE)

Genome-wide genetic analysis of polyploidy in yeast.

Storchová, Breneman, Cande, Dunn, Burbank, O'Toole, Pellman; (Journal Article)

Cloners break away from the herd.

Pearson; (News)

Coral reef diversity refutes the neutral theory of biodiversity.

Dornelas, Connolly, Hughes; (JOURNAL ARTICLE)

Speaking different languages on biodiversity.

Ewers, Rodrigues; (Letter)

Microstimulation of inferotemporal cortex influences face categorization.

Afraz, Kiani, Esteky; (JOURNAL ARTICLE)

Research highlights.

none; (JOURNAL ARTICLE)

Putting DNA on the map.

Thieffry; (JOURNAL ARTICLE)

Genetics: junk DNA as an evolutionary force.

Biémont, Vieira; (News)

Copycats gear up to dog biotech brands.

Wadman; (News)

Microbiology: death of a chaperone.

Montecucco, Molinari; (Comment, News)

Driven to market.

Lehrer; (News)

Developing diversity.

Karin; (JOURNAL ARTICLE)

Power and particles.

none; (Editorial)

50 & 100 years ago.

none; (JOURNAL ARTICLE)

Gluconeogenesis: re-evaluating the FOXO1-PGC-1alpha connection.

Schilling, Oeser, Boustead, Flemming, O'Brien; (Comment, Journal Article)

Abstractions.

none; (JOURNAL ARTICLE)

A novel reality.

Danger; (News)

Unburdened by proof.

Ellis; (JOURNAL ARTICLE)

Correction.

none; (JOURNAL ARTICLE)

Sidelines.

none; (JOURNAL ARTICLE)

Cosmic ripples net physics prize.

Sanderson, Hogan; (News)

Rapid subtropical North Atlantic salinity oscillations across Dansgaard-Oeschger cycles.

Schmidt, Vautravers, Spero; (Journal Article)

Science in Culture.

Grillo; (JOURNAL ARTICLE)

Operation Tesla.

Hecht; (Journal Article)

Hoyle's observations were right on the ball.

Rushton, Gray; (JOURNAL ARTICLE)

To build bridges, or to burn them.

none; (Editorial)

Environmental activism: in the name of nature.

Marris; (News)

Market watch.

Schiermeier; (JOURNAL ARTICLE)

Microbiology: resurrecting a broken genome.

Lovett; (Comment, News)

Arctic hydrology during global warming at the Palaeocene/Eocene thermal maximum.

Pagani, Pedentchouk, Huber, Sluijs, Schouten, Brinkhuis, Sinninghe Damsté, Dickens, Backman, Clemens, Cronin, Eynaud, Gattacceca, Jakobsson, Jordan, Kaminski, King, Koc, Martinez, Matthiessen, McInroy, Moore, Moran, O'regan, Onodera, Pälike, Rea, Rio, Sakamoto, Smith, Stein, St John, Suto, Suzuki, Takahashi, Watanabe, Yamamoto; (JOURNAL ARTICLE)

Earth Science: lost lithium found.

Widom; (Comment, News)

Biomechanics: robotic whiskers used to sense features.

Solomon, Hartmann; (Journal Article)

From in vivo to in silico biology and back.

Di Ventura, Lemerle, Michalodimitrakis, Serrano; (Journal Article)

News in brief.

none; (JOURNAL ARTICLE)

Electron acceleration from contracting magnetic islands during reconnection.

Drake, Swisdak, Che, Shay; (Journal Article)

Cell cycle: complex evolution.

Sherlock; (Comment, News)

Wikipedia rival calls in the experts.

Giles; (News)

One small step.

none; (JOURNAL ARTICLE)

Lithium isotope evidence for subduction-enriched mantle in the source of mid-ocean-ridge basalts.

Elliott, Thomas, Jeffcoate, Niu; (Journal Article)

Atomic physics: quantum leap from light to atoms.

Lukin, Eisaman; (Comment, News)

Q&A: Fabio Mussi.

Abbott; (Journal Article)

In brief.

none; (JOURNAL ARTICLE)

Quantum teleportation between light and matter.

Sherson, Krauter, Olsson, Julsgaard, Hammerer, Cirac, Polzik; (Journal Article)

Nanotechnology: downsizing SQUIDs.

Thomas; (News)

Learning from painful experience of disaster.

Oppenheimer; (Comment, Letter)

Making the paper: John Schuetz.

none; (JOURNAL ARTICLE)

Key contribution.

none; (JOURNAL ARTICLE)

Youthful duo snags a swift Nobel for RNA control of genes.

Abbott; (News)

Climate in court.

Marris; (News)

AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP.

Paton, Beddoe, Thorpe, Whisstock, Wilce, Rossjohn, Talbot, Paton; (Journal Article)

When it's personal.

Powell; (Journal Article)

Theorists snap over string pieces.

Brumfiel; (News)


Science

Eppendorf 2006 winner. A dedicated system for processing faces.

Tsao; (Journal Article)

Comment on "Pairing and phase separation in a polarized Fermi gas".

Zwierlein, Ketterle; (Comment, Journal Article)

Public health. Genomics and medicine at a crossroads in Chernobyl.

Ginsburg, Angrist, Cook-Deegan; (Journal Article)

Biologically based computational models of high-level cognition.

O'Reilly; (Journal Article)

Prying open the black box.

Bloom; (Editorial)

American Chemical Society meeting. Snapshots from the meeting.

Service; (Journal Article)

Generation of simian-tropic HIV-1 by restriction factor evasion.

Hatziioannou, Princiotta, Piatak, Yuan, Zhang, Lifson, Bieniasz; (Journal Article)

Nobel Prize in Physiology or Medicine. Method to silence genes earns loud praise.

Couzin; (Biography, News)

Eppendorf 2006 winner. 2006 grand prize winner.

none; (Comment, Journal Article)

Nonlinear dynamics. Bizarrely, adding delay to delay produces synchronization.

Cho; (News)

Science policy. Priorities needed for nano-risk research and development.

Service; (News)

On purpose in conservation.

Woodwell; (Comment, Letter)

Evolution. Fossil record reveals tropics as cradle and museum.

Marshall; (Comment, Journal Article)

Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior.

Chen, Jing, Bath, Ieraci, Khan, Siao, Herrera, Toth, Yang, McEwen, Hempstead, Lee; (Journal Article)

Cancer. Cancer immunotherapy is more than a numbers game.

Offringa; (Comment, Journal Article)

Astronomy. Galactic prominences on the rise.

Morris; (Comment, Journal Article)

U.S. competitiveness. Hopes for innovation bill rest on lame-duck Congress.

Mervis; (News)

John Niederhuber. A physician-scientist takes the helm of NCI.

Kaiser; (News)

Chemistry. Boron goes on the attack.

Marder; (Comment, Journal Article)

Extending top-down mass spectrometry to proteins with masses greater than 200 kilodaltons.

Han, Jin, Breuker, McLafferty; (Journal Article)

An enterprising approach to brain science.

Miller; (News)

Action of TFII-I outside the nucleus as an inhibitor of agonist-induced calcium entry.

Caraveo, van Rossum, Patterson, Snyder, Desiderio; (Journal Article)

Neurodegenerative diseases. Picking apart the causes of mysterious dementias.

Marx; (Comment, News)

Infectious prions in the saliva and blood of deer with chronic wasting disease.

Mathiason, Powers, Dahmes, Osborn, Miller, Warren, Mason, Hays, Hayes-Klug, Seelig, Wild, Wolfe, Spraker, Miller, Sigurdson, Telling, Hoover; (Journal Article)

Large punctuational contribution of speciation to evolutionary divergence at the molecular level.

Pagel, Venditti, Meade; (Journal Article)

Modeling single-neuron dynamics and computations: a balance of detail and abstraction.

Herz, Gollisch, Machens, Jaeger; (Journal Article)

From Plant Traits to Plant Communities: A Statistical Mechanistic Approach to Biodiversity.

Shipley, Vile, Garnier; (JOURNAL ARTICLE)

Preventing HIV/AIDS in adolescents.

Roberts; (Comment, Letter)

Cell signaling. The double life of a transcription factor takes it outside the nucleus.

Park, Dolmetsch; (Comment, Journal Article)

American Chemical Society meeting. Power to the (poor) people.

Service; (News)

John Niederhuber. Budgets, patients, managing conflicts.

Kaiser; (News)

Of Bytes and Brains.

Stern, Travis; (JOURNAL ARTICLE)

Neuronal computations with stochastic network states.

Destexhe, Contreras; (Journal Article)

Chemistry. Mass spectrometry: bottom-up or top-down?

Chait; (Comment, Journal Article)

Nobel Prize in Physics. Astrophysicists lauded for first baby picture of the universe.

Cho; (News)

Modulation of cell adhesion and motility in the immune system by Myo1f.

Kim, Mehal, Dong, Heinrich, Pypaert, Mellman, Dembo, Mooseker, Wu, Flavell; (Journal Article)

Barium Isotopes in Chondritic Meteorites: Implications for Planetary Reservoir Models.

Ranen, Jacobsen; (JOURNAL ARTICLE)

Genetics. Seeing a 'plot,' deCODE sues to block a DNA research center.

Marshall; (News)

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.

Neumann, Sampathu, Kwong, Truax, Micsenyi, Chou, Bruce, Schuck, Grossman, Clark, McCluskey, Miller, Masliah, Mackenzie, Feldman, Feiden, Kretzschmar, Trojanowski, Lee; (Journal Article)

Geochemistry. Has lazy mixing spoiled the primordial stew?

Kerr; (News)

Molecular loops in the galactic center: evidence for magnetic flotation.

Fukui, Yamamoto, Fujishita, Kudo, Torii, Nozawa, Takahashi, Matsumoto, Machida, Kawamura, Yonekura, Mizuno, Onishi, Mizuno; (Journal Article)

Biodefense. House passes plan for drug, vaccine R&D.

Kaiser; (News)

France. Presidential hopefuls discover a new issue: science.

Enserink; (News)

Out of the tropics: evolutionary dynamics of the latitudinal diversity gradient.

Jablonski, Roy, Valentine; (Journal Article)

Activity- and mTOR-dependent suppression of Kv1.1 channel mRNA translation in dendrites.

Raab-Graham, Haddick, Jan, Jan; (Journal Article)

Diminishing Reciprocal Fairness by Disrupting the Right Prefrontal Cortex.

Knoch, Pascual-Leone, Meyer, Treyer, Fehr; (JOURNAL ARTICLE)

Post-fire logging debate ignores many issues.

DellaSala, Karr, Schoennagel, Perry, Noss, Lindenmayer, Beschta, Hutto, Swanson, Evans; (Letter)

Solar Nebula Heterogeneity in p-Process Samarium and Neodymium Isotopes.

Andreasen, Sharma; (JOURNAL ARTICLE)

Polar research. U.S. needs new icebreakers, report tells Congress.

Mervis; (News)

Boryllithium: isolation, characterization, and reactivity as a boryl anion.

Segawa, Yamashita, Nozaki; (Journal Article)

Astronomy. Speedy planets near galactic center show sun's region is no fluke.

Schilling; (News)

Vision's grand theorist.

Wickelgren; (News)

American Chemical Society meeting. Cut-and-copy approach clones nanotubes.

Service; (News)


Nature Methods

Nonblinking and long-lasting single-molecule fluorescence imaging.

Rasnik, McKinney, Ha; (JOURNAL ARTICLE)


Nature Biotechnology

Protein chip fabrication by capture of nascent polypeptides.

Tao, Zhu; (JOURNAL ARTICLE)

Analyzing proteome topology and function by automated multidimensional fluorescence microscopy.

Schubert, Bonnekoh, Pommer, Philipsen, Böckelmann, Malykh, Gollnick, Friedenberger, Bode, Dress; (JOURNAL ARTICLE)


Nature Medicine

In vivo imaging of lymph node metastasis with telomerase-specific replication-selective adenovirus.

Kishimoto, Kojima, Watanabe, Kagawa, Fujiwara, Uno, Teraishi, Kyo, Mizuguchi, Hashimoto, Urata, Tanaka, Fujiwara; (JOURNAL ARTICLE)

Research highlights.

none; (Journal Article)

Growing pains.

none; (Journal Article)

Medical students protest perks from drug companies.

Opar; (Journal Article)

Quantifying viable virus-specific T cells without a priori knowledge of fine epitope specificity.

Beadling, Slifka; (Journal Article)

Controlling angiogenesis in heart valves.

Kalluri, Zeisberg; (JOURNAL ARTICLE)

Targeted cancer treatment: resisting arrest.

Wodarz; (Journal Article)

Erratum: Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing.

Thomas, Nickerson, Simons, Jänne, Tengs, Yuza, Garraway, Laframboise, Lee, Shah, O'neill, Sasaki, Lindeman, Wong, Borras, Gutmann, Dragnev, Debiasi, Chen, Glatt, Greulich, Desany, Lubeski, Brockman, Alvarez, Hutchison, Leamon, Ronan, Turenchalk, Egholm, Sellers, Rothberg, Meyerson; (Journal Article)

Multiple sclerosis: putting two and two together.

Trowsdale; (Journal Article)

Profile: stephen lewis.

Mandavilli; (Journal Article)

How an anomalous finding led to a new system of psychotherapy.

Beck; (Journal Article)

Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging.

Blackburn, Greider, Szostak; (Journal Article)

Alzheimer disease: BACE1 branches out.

Schubert; (Journal Article)

WHO's next?

none; (Journal Article)

Through the looking glass.

Gall; (Journal Article)

Scientists eye embryo-free methods to derive stem cells.

Goldman; (Journal Article)

News in brief.

none; (Journal Article)

Complement targeting of nonhuman sialic acid does not mediate cell death of human embryonic stem cells.

Cerdan, Bendall, Wang, Stewart, Werbowetski, Bhatia; (Journal Article)

Corrigendum: Nogo-A-specific antibody treatment enhances sprouting and functional recovery after cervical lesion in adult primates.

Freund, Schmidlin, Wannier, Bloch, Mir, Schwab, Rouiller; (Journal Article)

News feature: Crime and punishment.

Opar; (Journal Article)

In Search of One's Self.

Ledoux; (Journal Article)

Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications.

Roeder, Horn, Glauche, Hochhaus, Mueller, Loeffler; (Journal Article)

Spain's ill-conceived project leaves its scientists in the lurch.

Mandavilli; (Journal Article)

Defeating T-cell fatigue in HIV.

Farrell; (Journal Article)

Venture science: climbing the ladder to telomerase, cognitive therapy and in situ hybridization.

Goldstein; (Journal Article)

Alzheimer disease: presenilin springs a leak.

Gandy, Doeven, Poolman; (Journal Article)

Complement targeting of nonhuman sialic acid does not mediate cell death of human embryonic stem cells.

Martín, Muotri, Gage, Varki; (Journal Article)


Nature Genetics

Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus.

Tarpey, Thomas, Sarvananthan, Mallya, Lisgo, Talbot, Roberts, Awan, Surendran, McLean, Reinecke, Langmann, Lindner, Koch, Jain, Woodruff, Gale, Degg, Droutsas, Asproudis, Zubcov, Pieh, Veal, Machado, Backhouse, Baumber, Constantinescu, Brodsky, Hunter, Hertle, Read, Edkins, O'meara, Parker, Stevens, Teague, Wooster, Futreal, Trembath, Stratton, Raymond, Gottlob; (JOURNAL ARTICLE)

Differences in reactive oxygen species production explain the phenotypes associated with common mouse mitochondrial DNA variants.

Moreno-Loshuertos, Acín-Pérez, Fernández-Silva, Movilla, Pérez-Martos, de Cordoba, Gallardo, Enríquez; (JOURNAL ARTICLE)

Genome-wide analysis of estrogen receptor binding sites.

Carroll, Meyer, Song, Li, Geistlinger, Eeckhoute, Brodsky, Keeton, Fertuck, Hall, Wang, Bekiranov, Sementchenko, Fox, Silver, Gingeras, Liu, Brown; (JOURNAL ARTICLE)

Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer.

Sung, Gao, Shen, Yu, Song, Smith, Chang, Inoue, Kuo, Lian, Li, Tian, Tuck, Weissman, Yang, Cheng; (JOURNAL ARTICLE)

Regulation of primary cilia formation and left-right patterning in zebrafish by a noncanonical Wnt signaling mediator, duboraya.

Oishi, Kawakami, Raya, Callol-Massot, Belmonte; (JOURNAL ARTICLE)


Molecular Medicine


Proteomics

In this issue: Proteomics 19/2006.

none; (JOURNAL ARTICLE)

Proteomic-based analysis of nuclear signaling: PLCbeta(1) affects the expression of the splicing factor SRp20 in Friend erythroleukemia cells.

Bavelloni, Faenza, Cioffi, Piazzi, Parisi, Matic, Maraldi, Cocco; (JOURNAL ARTICLE)

Fast track to a phosphoprotein sketch - MALDI-TOF characterization of TLC-based tryptic phosphopeptide maps at femtomolar detection sensitivity.

Kochin, Imanishi, Eriksson; (JOURNAL ARTICLE)

Serum, liver, and kidney proteomic analysis for the alloxan-induced type I diabetic mice after insulin gene transfer of naked plasmid through electroporation.

Diao, Chen, Wu, Liu, Xie, Li, Shen, Ji; (JOURNAL ARTICLE)

Optimization of paper bridge loading for 2-DE analysis in the basic pH region: Application to the mitochondrial subproteome.

Kane, Yung, Agnetti, Neverova, Van Eyk; (JOURNAL ARTICLE)

The ROP2 family of Toxoplasma gondii rhoptry proteins: Proteomic and genomic characterization and molecular modeling.

El Hajj, Demey, Poncet, Lebrun, Wu, Galéotti, Fourmaux, Mercereau-Puijalon, Vial, Labesse, Dubremetz; (JOURNAL ARTICLE)

Parallel protein and transcript profiles of FSHD patient muscles correlate to the D4Z4 arrangement and reveal a common impairment of slow to fast fibre differentiation and a general deregulation of MyoD-dependent genes.

Celegato, Capitanio, Pescatori, Romualdi, Pacchioni, Cagnin, Viganò, Colantoni, Begum, Ricci, Wait, Lanfranchi, Gelfi; (JOURNAL ARTICLE)

Meetings Diary: Proteomics 19/2006.

none; (JOURNAL ARTICLE)

Identification of proteins of potential diagnostic value for bovine paratuberculosis.

Cho, Sung, Collins; (JOURNAL ARTICLE)

Protein expression of lymphocytes in HLA-DR transgenic pigs by a proteomic approach.

Huang, Chen, Teng, Chen, Ho, Tu; (JOURNAL ARTICLE)

Proteomic analysis of the mouse mammary gland is a powerful tool to identify novel proteins that are differentially expressed during mammary development.

Davies, Morris, Griffiths, Page, Pitt, Stein, Gusterson; (JOURNAL ARTICLE)

Proteomic search for potential diagnostic markers and therapeutic targets for ovarian clear cell adenocarcinoma.

Morita, Miyagi, Yasumitsu, Kawasaki, Hirano, Hirahara; (JOURNAL ARTICLE)


Nature Drug Discovery


BMC Bioinformatics

PubFocus: Semantic MEDLINE/PubMed citations analytics through integration of controlled biomedical dictionaries and ranking algorithm.

Plikus, Zhang, Chuong; (JOURNAL ARTICLE)

The BiSearch web server.

Aranyi, Varadi, Simon, Tusnady; (JOURNAL ARTICLE)

M-GCAT: Interactively and efficiently constructing large-scale multiple genome comparison frameworks in closely related species.

Treangen, Messeguer; (JOURNAL ARTICLE)

Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle.

Wu, Li, Chen; (JOURNAL ARTICLE)

XRate: a fast prototyping, training and annotation tool for phylo-grammars.

Klosterman, Uzilov, Bendana, Bradley, Chao, Kosiol, Goldman, Holmes; (JOURNAL ARTICLE)

Detection of prokaryotic promoters from the genomic distribution of hexanucleotide pairs.

Jacques, Rodrigue, Gaudreau, Goulet, Brzezinski; (JOURNAL ARTICLE)

Predicting residue-wise contact orders in proteins by support vector regression.

Song, Burrage; (JOURNAL ARTICLE)

Grouping Gene Ontology terms to improve the assessment of gene set enrichment in microarray data.

Lewin, Grieve; (JOURNAL ARTICLE)

MICA: desktop software for comprehensive searching of DNA databases.

Stokes, Glick; (JOURNAL ARTICLE)

Analysis with respect to instrumental variables for the exploration of microarray data structures.

Baty, Facompre, Wiegand, Schwager, Brutsche; (JOURNAL ARTICLE)

Rank-statistics based enrichment-site prediction algorithm developed for chromatin immunoprecipitation on chip experiments.

Ghosh, Hirsch, Sekinger, Struhl, Gingeras; (JOURNAL ARTICLE)

Coloring the Mu transpososome.

Darcy, Chang, Druivenga, McKinney, Medikonduri, Mills, Navarra-Madsen, Ponnusamy, Sweet, Thompson; (JOURNAL ARTICLE)

Development of an open source laboratory information management system for 2-D gel electrophoresis-based proteomics workflow.

Morisawa, Hirota, Toda; (JOURNAL ARTICLE)

Design of a combinatorial DNA microarray for protein-DNA interaction studies.

Mintseris, Eisen; (JOURNAL ARTICLE)

Feature selection using Haar wavelet power spectrum.

Subramani, Sahu, Verma; (JOURNAL ARTICLE)


Bioinformatics

ProtBuD: a database of biological unit structures of protein families and superfamilies.

Xu, Canutescu, Obradovic, Dunbrack; (JOURNAL ARTICLE)

The tYNA platform for comparative interactomics: a web tool for managing, comparing and mining multiple networks.

Yip, Yu, Kim, Schultz, Gerstein; (JOURNAL ARTICLE)

GenoProfiler: batch processing of high throughput capillary fingerprinting data.

You, Luo, Gu, Lazo, Deal, Dvorak, Anderson; (JOURNAL ARTICLE)

CREMOFAC - A database of chromatin remodeling factors.

Shipra, Chetan, Rao; (JOURNAL ARTICLE)

Analysis of HIV-1 pol sequences using Bayesian networks: implications for drug resistance.

Deforche, Silander, Camacho, Grossman, Soares, Van Laethem, Kantor, Moreau, Vandamme; (JOURNAL ARTICLE)

P2BAT: A Massive Parallel Implementation of PBAT for Genome-Wide Association Studies in R.

Hoffmann, Lange; (JOURNAL ARTICLE)

FoldUnfold: web server for the prediction of disordered regions in protein chain.

Galzitskaya, Garbuzynskiy, Lobanov; (JOURNAL ARTICLE)

TimeTree: a public knowledge-base of divergence times among organisms.

Hedges, Dudley, Kumar; (JOURNAL ARTICLE)

A novel algorithm for identifying low-complexity regions in a protein sequence.

Li, Kahveci; (JOURNAL ARTICLE)

Sungear: interactive visualization and functional analysis of genomic datasets.

Poultney, Gutiérrez, Katari, Gifford, Paley, Coruzzi, Shasha; (JOURNAL ARTICLE)

Predicted function of the vaccinia virus G5R protein.

Da Silva, Shen, Tcherepanov, Watson, Upton; (JOURNAL ARTICLE)


Proc Natl Acad Sci U S A

The structure of human ADP-ribosylhydrolase 3 (ARH3) provides insights into the reversibility of protein ADP-ribosylation.

Mueller-Dieckmann, Kernstock, Lisurek, von Kries, Haag, Weiss, Koch-Nolte; (JOURNAL ARTICLE)

Enzyme therapy in mannose receptor-null mucopolysaccharidosis VII mice defines roles for the mannose 6-phosphate and mannose receptors.

Sly, Vogler, Grubb, Levy, Galvin, Tan, Nishioka, Tomatsu; (JOURNAL ARTICLE)

Diacylglycerol kinase {delta} regulates protein kinase C and epidermal growth factor receptor signaling.

Crotty, Cai, Sakane, Taketomi, Prescott, Topham; (JOURNAL ARTICLE)

Gastric stimulation in obese subjects activates the hippocampus and other regions involved in brain reward circuitry.

Wang, Yang, Volkow, Telang, Ma, Zhu, Wong, Tomasi, Thanos, Fowler; (JOURNAL ARTICLE)

A molecular neuroethological approach for identifying and characterizing a cascade of behaviorally regulated genes.

Wada, Howard, McConnell, Whitney, Lints, Rivas, Horita, Patterson, White, Scharff, Haesler, Zhao, Sakaguchi, Hagiwara, Shiraki, Hirozane-Kishikawa, Skene, Hayashizaki, Carninci, Jarvis; (JOURNAL ARTICLE)

A retrovirus-based protein complementation assay screen reveals functional AKT1-binding partners.

Ding, Liang, Lu, Yu, Songyang, Lin, Mills; (JOURNAL ARTICLE)

Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies.

Liu, Chang, Herberg, Horng, Tomich, Lin, Marotti; (JOURNAL ARTICLE)

Protein complex formation by acetylcholinesterase and the neurotoxin fasciculin-2 appears to involve an induced-fit mechanism.

Bui, McCammon; (JOURNAL ARTICLE)

The plasma membrane Na+/H+ antiporter SOS1 interacts with RCD1 and functions in oxidative stress tolerance in Arabidopsis.

Katiyar-Agarwal, Zhu, Kim, Agarwal, Fu, Huang, Zhu; (JOURNAL ARTICLE)

Of mice and sperm.

Pizzari; (JOURNAL ARTICLE)

The history of early bee diversification based on five genes plus morphology.

Danforth, Sipes, Fang, Brady; (JOURNAL ARTICLE)

Ultrafast infrared spectroscopy reveals a key step for successful entry into the photocycle for photoactive yellow protein.

van Wilderen, van der Horst, van Stokkum, Hellingwerf, van Grondelle, Groot; (JOURNAL ARTICLE)

Recent progress in understanding hydrophobic interactions.

Meyer, Rosenberg, Israelachvili; (JOURNAL ARTICLE)

Detecting emerging strains of tuberculosis by using spoligotypes.

Tanaka, Francis; (JOURNAL ARTICLE)

Neuropathy target esterase catalyzes osmoprotective renal synthesis of glycerophosphocholine in response to high NaCl.

Gallazzini, Ferraris, Kunin, Morris, Burg; (JOURNAL ARTICLE)

Structural basis for understanding oncogenic p53 mutations and designing rescue drugs.

Joerger, Ang, Fersht; (JOURNAL ARTICLE)

Slow progressive degeneration of nigral dopaminergic neurons in postnatal Engrailed mutant mice.

Sgadò, Albéri, Gherbassi, Galasso, Ramakers, Alavian, Smidt, Dyck, Simon; (JOURNAL ARTICLE)

DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2.

Clements, McNally, Conti, Mak, Ting; (JOURNAL ARTICLE)

Generation of heavy-chain-only antibodies in mice.

Janssens, Dekker, Hendriks, Panayotou, van Remoortere, Kong-A San, Grosveld, Drabek; (JOURNAL ARTICLE)

Androgen receptor as a licensing factor for DNA replication in androgen-sensitive prostate cancer cells.

Litvinov, Vander Griend, Antony, Dalrymple, De Marzo, Drake, Isaacs; (JOURNAL ARTICLE)

Evolution of sensory complexity recorded in a myxobacterial genome.

Goldman, Nierman, Kaiser, Slater, Durkin, Eisen, Ronning, Barbazuk, Blanchard, Field, Halling, Hinkle, Iartchuk, Kim, Mackenzie, Madupu, Miller, Shvartsbeyn, Sullivan, Vaudin, Wiegand, Kaplan; (JOURNAL ARTICLE)

Interdigital webbing retention in bat wings illustrates genetic changes underlying amniote limb diversification.

Weatherbee, Behringer, Rasweiler, Niswander; (JOURNAL ARTICLE)

Artificial evolution extends the spectrum of viruses that are targeted by a disease-resistance gene from potato.

Farnham, Baulcombe; (JOURNAL ARTICLE)

Functional units in the olfactory system.

Leon, Johnson; (JOURNAL ARTICLE)

A nucleobase lesion remodels the interaction of its normal neighbor in a DNA glycosylase complex.

Banerjee, Verdine; (JOURNAL ARTICLE)

Evidence for licensing of IFN-{gamma}-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program.

Negishi, Fujita, Yanai, Sakaguchi, Ouyang, Shinohara, Takayanagi, Ohba, Taniguchi, Honda; (JOURNAL ARTICLE)

TEL-AML1 transgenic zebrafish model of precursor B cell acute lymphoblastic leukemia.

Sabaawy, Azuma, Embree, Tsai, Starost, Hickstein; (JOURNAL ARTICLE)

The omega-3 fatty acid docosahexaenoate attenuates endothelial cyclooxygenase-2 induction through both NADP(H) oxidase and PKC{varepsilon} inhibition.

Massaro, Habib, Lubrano, Del Turco, Lazzerini, Bourcier, Weksler, De Caterina; (JOURNAL ARTICLE)

Ionic control of ocular growth and refractive change.

Crewther, Liang, Junghans, Crewther; (JOURNAL ARTICLE)

Epizootics of wild fish induced by farm fish.

Krkosek, Lewis, Morton, Frazer, Volpe; (JOURNAL ARTICLE)

A role for WRN in telomere-based DNA damage responses.

Eller, Liao, Liu, Hanna, Bäckvall, Opresko, Bohr, Gilchrest; (JOURNAL ARTICLE)

Selective fluorescent imaging of superoxide in vivo using ethidium-based probes.

Robinson, Janes, Pehar, Monette, Ross, Hagen, Murphy, Beckman; (JOURNAL ARTICLE)

Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism.

Brown, Caradoc-Davies, Dickson, Cooper, Loomes, Baker; (JOURNAL ARTICLE)

Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.

Lee, Lee, Dou, Lee, Lee, Kwak, Kong, Lee, Roeder, Lee; (JOURNAL ARTICLE)

The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia.

Dunfee, Thomas, Gorry, Wang, Taylor, Kunstman, Wolinsky, Gabuzda; (JOURNAL ARTICLE)

Culling and cattle controls influence tuberculosis risk for badgers.

Woodroffe, Donnelly, Jenkins, Johnston, Cox, Bourne, Cheeseman, Delahay, Clifton-Hadley, Gettinby, Gilks, Hewinson, McInerney, Morrison; (Journal Article)

The GLD-2 poly(A) polymerase activates gld-1 mRNA in the Caenorhabditis elegans germ line.

Suh, Jedamzik, Eckmann, Wickens, Kimble; (JOURNAL ARTICLE)

Mapping protein dynamics in catalytic intermediates of the redox-driven proton pump cytochrome c oxidase.

Busenlehner, Salomonsson, Brzezinski, Armstrong; (JOURNAL ARTICLE)

Predicted climate change alters the indirect effect of predators on an ecosystem process.

Lensing, Wise; (JOURNAL ARTICLE)

Disrupted motor learning and long-term synaptic plasticity in mice lacking NMDAR1 in the striatum.

Dang, Yokoi, Yin, Lovinger, Wang, Li; (JOURNAL ARTICLE)

Variation at the rat Crhr1 locus and sensitivity to relapse into alcohol seeking induced by environmental stress.

Hansson, Cippitelli, Sommer, Fedeli, Björk, Soverchia, Terasmaa, Massi, Heilig, Ciccocioppo; (JOURNAL ARTICLE)

The piggyBac transposon holds promise for human gene therapy.

Feschotte; (JOURNAL ARTICLE)

Similarities between heterophilic and homophilic cadherin adhesion.

Prakasam, Maruthamuthu, Leckband; (JOURNAL ARTICLE)


N Engl J Med

Inhaled carbon and lung function in children.

Bates, Hogg; (Comment, Letter)

The new era of medical imaging.

Nissen; (Comment, Letter)

Treatment of gastric cancer.

Lloyd, Gabe; (Comment, Letter)

Treatment of gastric cancer.

Boot, Jansen, Cats; (Comment, Letter)

N-acetylcysteine and contrast-induced nephropathy.

Aguiar-Souto, Valero-González, Domínguez; (Comment, Letter)

N-acetylcysteine and contrast-induced nephropathy.

Wolak, Cafri, Zahger; (Comment, Letter)

Images in clinical medicine. Arteriovenous fistula on CT angiography.

Laureys; (Journal Article)

Ranibizumab versus verteporfin for neovascular age-related macular degeneration.

Brown, Kaiser, Michels, Soubrane, Heier, Kim, Sy, Schneider; (Journal Article)

Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis.

Creticos, Schroeder, Hamilton, Balcer-Whaley, Khattignavong, Lindblad, Li, Coffman, Seyfert, Eiden, Broide; (Journal Article)

Images in clinical medicine. Yellow palms and soles in diabetes mellitus.

Lin; (Journal Article)

Retinol-binding protein 4 and insulin resistance.

Oh; (Comment, Letter)

An aging un-American.

Scannell; (Journal Article)

More on case 7-2006.

Diskin; (Comment, Letter)

Culture of T. whipplei from the stool of a patient with Whipple's disease.

Raoult, Fenollar, Birg; (Letter)

Age-related macular degeneration.

de Jong; (Journal Article)

Treatment of gastric cancer.

Harewood; (Comment, Letter)

Homocysteine lowering and cognitive performance.

Dettling, Opgen-Rhein, Anghelescu; (Comment, Letter)

Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion.

List, Dewald, Bennett, Giagounidis, Raza, Feldman, Powell, Greenberg, Thomas, Stone, Reeder, Wride, Patin, Schmidt, Zeldis, Knight; (Journal Article)

Homocysteine lowering and cognitive performance.

Narayan; (Comment, Letter)

Iodine nutrition--more is better.

Morreale de Escobar, Escobar del Rey; (Comment, Letter)

Molecular mechanisms in melanoma.

Vale; (Comment, Letter)

Condom use and the risk of HPV infection.

Cottler, Garvin, Callahan; (Comment, Letter)

Ranibizumab for neovascular age-related macular degeneration.

Rosenfeld, Brown, Heier, Boyer, Kaiser, Chung, Kim; (Journal Article)

Molecular mechanisms in melanoma.

Ugurel, Houben, Becker; (Comment, Letter)

N-acetylcysteine and contrast-induced nephropathy.

Balderramo; (Comment, Letter)

Clinical problem-solving. Lost in transcription.

Kalus, Shojania, Amory, Saint; (Journal Article)

Treatment of gastric cancer.

Fielding, Peake; (Comment, Letter)

N-acetylcysteine and contrast-induced nephropathy.

Ritz; (Comment, Letter)

The price of sight--ranibizumab, bevacizumab, and the treatment of macular degeneration.

Steinbrook; (Comment, Journal Article)

Treatment of gastric cancer.

Jani; (Comment, Letter)

The new era of medical imaging.

Williams; (Comment, Letter)

A very effective treatment for neovascular macular degeneration.

Stone; (Comment, Editorial)

Clinical practice. Prevention of meningococcal disease.

Gardner; (Journal Article)

Iodine nutrition--more is better.

Pearce, Hollowell; (Comment, Letter)

Inhaled carbon and lung function in children.

Gohil; (Comment, Letter)

Tracing atrial fibrillation--100 years.

Fye; (Journal Article)

Retinol-binding protein 4 and insulin resistance.

Erikstrup, Mortensen, Pedersen; (Comment, Letter)

Inhaled carbon and lung function in children.

Bruce, Dherani, Smith; (Comment, Letter)


J Natl Cancer Inst

Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal women.

Eliassen, Missmer, Tworoger, Spiegelman, Barbieri, Dowsett, Hankinson; (Journal Article)

Re: Human papillomavirus infection and incidence of squamous cell and basal cell carcinomas of the skin.

Hall, Struijk, Neale, Feltkamp; (Comment, Letter)

Decades After Cancer, Suicide Risk Remains High.

Twombly; (JOURNAL ARTICLE)

FDA revamps committee conflict-of-interest rules.

Finkelstein; (News)

Stat bite: Suicide circumstances, 2003-2004.

none; (Journal Article)

Re: Randomized double-blind factorial trial of three treatments to reduce the prevalence of precancerous gastric lesions.

Mera, Fontham, Bravo, Bravo, Piazuelo, Camargo, Correa; (Comment, Letter)

Menopausal hormone therapy and ovarian cancer risk in the National Institutes of Health-AARP Diet and Health Study Cohort.

Lacey, Brinton, Leitzmann, Mouw, Hollenbeck, Schatzkin, Hartge; (Journal Article)

Suicide after breast cancer: an international population-based study of 723,810 women.

Schairer, Brown, Chen, Howard, Lynch, Hall, Storm, Pukkala, Anderson, Kaijser, Andersson, Joensuu, Fosså, Ganz, Travis; (Journal Article)

Zinc-alpha2-glycoprotein expression as a predictor of metastatic prostate cancer following radical prostatectomy.

Henshall, Horvath, Quinn, Eggleton, Grygiel, Stricker, Biankin, Kench, Sutherland; (Journal Article)

Chlamydia or not Chlamydia, that is the question: which is the microorganism associated with MALT lymphomas of the ocular adnexa?

Zucca, Bertoni; (Comment, Editorial)

Can mutations in gamma-actin modulate the toxicity of microtubule targeting agents?

Fojo; (Comment, Editorial)

New options expand possibilities for fertility preservation in cancer patients.

Whitworth; (News)

Alterations in gamma-actin and tubulin-targeted drug resistance in childhood leukemia.

Verrills, Po'uha, Liu, Liaw, Larsen, Ivery, Marshall, Gunning, Kavallaris; (Journal Article)

Bacteria-eradicating therapy with doxycycline in ocular adnexal MALT lymphoma: a multicenter prospective trial.

Ferreri, Ponzoni, Guidoboni, Resti, Politi, Cortelazzo, Demeter, Zallio, Palmas, Muti, Dognini, Pasini, Lettini, Sacchetti, De Conciliis, Doglioni, Dolcetti; (Journal Article)

Freezing embryos--a woman's best option, but is it legal?

Whitworth; (News)

Commonly studied single-nucleotide polymorphisms and breast cancer: results from the Breast Cancer Association Consortium.

Breast Cancer Association Consortium; (Journal Article)

Common genetic variants for breast cancer: 32 largely refuted candidates and larger prospects.

Ioannidis; (Editorial)

Surgeon General's report heralds turning tide against tobacco, smoking.

Finkelstein; (News)


Lancet

Obstetric vesicovaginal fistula as an international public-health problem.

Wall; (Journal Article)

Estimating cardiovascular disease risk in diabetes - Authors' reply.

Booth, Kapral, Tu; (LETTER)

Healthy motherhood: an urgent call to action.

Horton; (Journal Article)

Overview of randomised trials of ACE inhibitors.

Bonne, Fournier, Massy, Choukroun, Fournier; (Comment, Letter)

Reducing poverty by investing in young people.

none; (Editorial)

Interpregnancy weight change and risk of adverse pregnancy outcomes: a population-based study.

Villamor, Cnattingius; (Journal Article)

Complications of obstructed labour: pressure necrosis of neonatal scalp and vesicovaginal fistula.

van Beekhuizen, Unkels, Mmuni, Kaiser; (Journal Article)

Intravenous drug use and HIV: evidence for action now.

none; (Editorial)

Malaria and deaths in the English marshes.

Watts; (Comment, Letter)

The challenge facing the NHS is leadership.

none; (Editorial)

Limitation in paediatric logistic organ dysfunction score - Authors' reply.

Leteurtre, Duhamel, Grandbastien, Lacroix, Leclerc; (LETTER)

Safe motherhood initiative: 20 years and counting.

Starrs; (Journal Article)

Limitation in paediatric logistic organ dysfunction score.

Garcia, Eulmesekian, Sffogia, Perez, Branco, Piva, Tasker; (Comment, Letter)

South African Health Minister must go, say scientists.

Kapp; (News)

Women's groups' perceptions of maternal health issues in rural Malawi.

Rosato, Mwansambo, Kazembe, Phiri, Soko, Lewycka, Kunyenge, Vergnano, Osrin, Newell, Costello; (Journal Article)

Women's wisdom--a source of knowledge for medicine.

Malterud; (Comment, Journal Article)

Mulu Muleta: Ethiopian surgeon working to end fistula.

Wakabi; (News)

Medical therapy to facilitate urinary stone passage: a meta-analysis.

Hollingsworth, Rogers, Kaufman, Bradford, Saint, Wei, Hollenbeck; (Journal Article)

Primary prevention of cardiovascular disease with pravastatin in Japan (MEGA Study): a prospective randomised controlled trial.

Nakamura, Arakawa, Itakura, Kitabatake, Goto, Toyota, Nakaya, Nishimoto, Muranaka, Yamamoto, Mizuno, Ohashi; (Journal Article)

Japan: are statins still good for everybody?

Sirtori, Calabresi; (Comment, Journal Article)

US advisory panel revisits prison research rules.

Loewenberg; (News)

Estimating cardiovascular disease risk in diabetes.

Auer, Lamm, Eber; (Comment, Letter)

Obesity, weight loss, and pregnancy outcomes.

Caughey; (Comment, Journal Article)

Malaria and deaths in the English marshes - Authors' reply.

Lindsay, Hutchinson; (LETTER)

Estimating cardiovascular disease risk in diabetes.

Bhala; (Comment, Letter)

Estimating cardiovascular disease risk in diabetes.

Sjöholm, Zimmet, Shaw; (Comment, Letter)

Meeting MDG-5: an impossible dream?

Rosenfield, Maine, Freedman; (Journal Article)

Neutrophils and sepsis.

Maugeri, Cerletti, Donati, de Gaetano, Vermylen; (Comment, Letter)

Medical therapy for urinary stone passage.

Pearle; (Comment, Journal Article)

Maternal mortality: who, when, where, and why.

Ronsmans, Graham; (Journal Article)

Local brain drain.

Kassaye; (Letter)


Expert Rev Mol Diagn

Amino-terminal pro-brain natriuretic peptide: a biomarker for diagnosis, prognosis and management of heart failure.

Morello, Januzzi; (Journal Article)

Pattern recognition and biomarker validation using quantitative 1H-NMR-based metabolomics.

Serkova, Niemann; (Journal Article)

Clinical assessment of assays for diagnosis of herpes simplex infection.

Ryan, Kinghorn; (Journal Article)

Use of gene expression microarrays for the study of acute leukemia.

Bellido, Stirewalt, Zhao, Radich; (Journal Article)

PCR troubleshooting. The essential guide.

Khrapko; (Journal Article)

Use of nanotechnology for the development of novel cancer biomarkers.

Banerjee, Verma; (Journal Article)

Blood cardiac troponin in toxic myocardial injury: archetype of a translational safety biomarker.

O'Brien; (Journal Article)

Microarray RNA transcriptional profiling: part II. Analytical considerations and annotation.

Ahmed; (Journal Article)

A novel high-sensitivity diagnostic test for B-CLL.

none; (News)

QuantiFERON-TB Gold: state of the art for the diagnosis of tuberculosis infection?

Connell, Rangaka, Curtis, Wilkinson; (Journal Article)

Rapid antigen detection testing in diagnosing group A beta-hemolytic streptococcal pharyngitis.

Leung, Newman, Kumar, Davies; (Journal Article)

Signal amplification systems in immunoassays: implications for clinical diagnostics.

Dhawan; (Journal Article)