Nature

Finlayson, Giles Pacheco, Rodríguez-Vidal, Fa, María Gutierrez López, Santiago Pérez, Finlayson, Allue, Baena Preysler, Cáceres, Carrión, Fernández Jalvo, Gleed-Owen, Jimenez Espejo, López, Antonio López Sáez, Antonio Riquelme Cantal, Sánchez Marco, Giles Guzman, Brown, Fuentes, Valarino, Villalpando, Stringer, Martinez Ruiz, Sakamoto; (JOURNAL ARTICLE)

Nanotech's big issue.

none; (Journal Article)

Cooling a nanomechanical resonator with quantum back-action.

Naik, Buu, LaHaye, Armour, Clerk, Blencowe, Schwab; (Journal Article)

Land-atmosphere coupling and climate change in Europe.

Seneviratne, Lüthi, Litschi, Schär; (Journal Article)

Variations in solar luminosity and their effect on the Earth's climate.

Foukal, Fröhlich, Spruit, Wigley; (Journal Article)

A galaxy at a redshift z = 6.96.

Iye, Ota, Kashikawa, Furusawa, Hashimoto, Hattori, Matsuda, Morokuma, Ouchi, Shimasaku; (Journal Article)

Cancer biology: can less be more for p53?

Berns; (Comment, News)

Snapshot: women at work.

Abbott; (News)

Astronomy: dawn after the dark age.

McMahon; (Comment, News)

Flickers of consciousness.

none; (Editorial)

Whistleblowers in peril.

none; (Editorial)

Back on track.

Masten; (JOURNAL ARTICLE)

Neutrinos make a splash in Italy.

Nosengo; (News)

'Vegetative' patient shows signs of conscious thought.

Hopkin; (News)

Climate change: a cosmic connection.

Kanipe; (News)

Science

Scientific community. Campaign heats up for WHO Director-General.

Vogel; (News)

Geochemistry. Radiocarbon dating's final frontier.

Balter; (News)

Early reactivation of European rivers during the last deglaciation.

Ménot, Bard, Rostek, Weijers, Hopmans, Schouten, Sinninghe Damsté; (Journal Article)

C-terminal signal sequence promotes virulence factor secretion in Mycobacterium tuberculosis.

Champion, Stanley, Champion, Brown, Cox; (Journal Article)

Animal activism: out of control.

Kennedy; (Editorial)

Genomics. Poplar tree sequence yields genome double take.

Stokstad; (Comment, News)

High gamma power is phase-locked to theta oscillations in human neocortex.

Canolty, Edwards, Dalal, Soltani, Nagarajan, Kirsch, Berger, Barbaro, Knight; (Journal Article)

Support for the NIH public access policy.

Rogawski, Suber; (Comment, Letter)

Microbiology. Mycobacteria's export strategy.

Ize, Palmer; (Comment, Journal Article)

Physics. Detecting and controlling electron correlations.

Büttiker; (Journal Article)

Astrophysics. Pulsars' gyrations confirm Einstein's theory.

Cho; (News)

Caveolin-1 is essential for liver regeneration.

Fernández, Albor, Ingelmo-Torres, Nixon, Ferguson, Kurzchalia, Tebar, Enrich, Parton, Pol; (Journal Article)

Paleoanthropology. Mild climate, lack of moderns let last Neandertals linger in Gibraltar.

Balter; (News)

Cuts in Homeland Security research.

Busta, Clarke, Goldman, Haas, Kelen, Lafree, Rose, von Winterfeldt; (Comment, Letter)

Evidence for a polar ethane cloud on Titan.

Griffith, Penteado, Rannou, Brown, Boudon, Baines, Clark, Drossart, Buratti, Nicholson, McKay, Coustenis, Negrao, Jaumann; (Journal Article)

Tests of General Relativity from Timing the Double Pulsar.

Kramer, Stairs, Manchester, McLaughlin, Lyne, Ferdman, Burgay, Lorimer, Possenti, D'Amico, Sarkissian, Hobbs, Reynolds, Freire, Camilo; (JOURNAL ARTICLE)

Bias about climate change.

Neal; (Comment, Letter)

Structural biology. Dynamic visions of enzymatic reactions.

Vendruscolo, Dobson; (Comment, Journal Article)

Astrophysics. Space mission to shine a light on solar flares.

Normile; (News)

The dynamic energy landscape of dihydrofolate reductase catalysis.

Boehr, McElheny, Dyson, Wright; (Journal Article)

Comment on "Large-scale sequence analysis of avian influenza isolates".

Holmes, Lipman, Zamarin, Yewdell; (Comment, Journal Article)

Oldest writing in the New World.

Rodríguez Martínez, Ortíz Ceballos, Coe, Diehl, Houston, Taube, Delgado Calderón; (Journal Article)

A Combined Mitigation/Geoengineering Approach to Climate Stabilization.

Wigley; (JOURNAL ARTICLE)

The genome of black cottonwood, Populus trichocarpa (Torr. & Gray).

Tuskan, Difazio, Jansson, Bohlmann, Grigoriev, Hellsten, Putnam, Ralph, Rombauts, Salamov, Schein, Sterck, Aerts, Bhalerao, Bhalerao, Blaudez, Boerjan, Brun, Brunner, Busov, Campbell, Carlson, Chalot, Chapman, Chen, Cooper, Coutinho, Couturier, Covert, Cronk, Cunningham, Davis, Degroeve, Déjardin, Depamphilis, Detter, Dirks, Dubchak, Duplessis, Ehlting, Ellis, Gendler, Goodstein, Gribskov, Grimwood, Groover, Gunter, Hamberger, Heinze, Helariutta, Henrissat, Holligan, Holt, Huang, Islam-Faridi, Jones, Jones-Rhoades, Jorgensen, Joshi, Kangasjärvi, Karlsson, Kelleher, Kirkpatrick, Kirst, Kohler, Kalluri, Larimer, Leebens-Mack, Leplé, Locascio, Lou, Lucas, Martin, Montanini, Napoli, Nelson, Nelson, Nieminen, Nilsson, Pereda, Peter, Philippe, Pilate, Poliakov, Razumovskaya, Richardson, Rinaldi, Ritland, Rouzé, Ryaboy, Schmutz, Schrader, Segerman, Shin, Siddiqui, Sterky, Terry, Tsai, Uberbacher, Unneberg, Vahala, Wall, Wessler, Yang, Yin, Douglas, Marra, Sandberg, Van de Peer, Rokhsar; (Journal Article)

Planetary science. Titan's polar weather.

Flasar; (Comment, Journal Article)

Invasive species. The Galapagos Islands kiss their goat problem goodbye.

Guo; (News)

Ongoing controversy over Debye's WWII role.

; (Comment, Letter)

Archaeology. Claim of oldest New World writing excites archaeologists.

Lawler; (Comment, News)

Public access success at PubMed.

Beebe; (Comment, Letter)

U.S. graduate education. Foreign enrollment rebounds after 3-year slump.

Bhattacharjee; (News)

Coherent Dynamics of Coupled Electron and Nuclear Spin Qubits in Diamond.

Childress, Dutt, Taylor, Zibrov, Jelezko, Wrachtrup, Hemmer, Lukin; (JOURNAL ARTICLE)

An alternative bactericidal mechanism of action for lantibiotic peptides that target lipid II.

Hasper, Kramer, Smith, Hillman, Zachariah, Kuipers, de Kruijff, Breukink; (Journal Article)

Probing nanoscale ferroelectricity by ultraviolet Raman spectroscopy.

Tenne, Bruchhausen, Lanzillotti-Kimura, Fainstein, Katiyar, Cantarero, Soukiassian, Vaithyanathan, Haeni, Tian, Schlom, Choi, Kim, Eom, Sun, Pan, Li, Chen, Jia, Nakhmanson, Rabe, Xi; (Journal Article)

Chemistry. The organic approach to asymmetric catalysis.

List, Yang; (Journal Article)

Near-field microscopy through a SiC superlens.

Taubner, Korobkin, Urzhumov, Shvets, Hillenbrand; (Journal Article)

Cell biology. A metabolic push to proliferate.

Brasaemle; (Comment, Journal Article)

Herpes Simplex Virus Encephalitis in Human UNC-93B Deficiency.

Casrouge, Zhang, Eidenschenk, Jouanguy, Puel, Yang, Alcais, Picard, Mahfoufi, Nicolas, Lorenzo, Plancoulaine, Sénéchal, Geissmann, Tabeta, Hoebe, Du, Miller, Héron, Mignot, Billette de Villemeur, Lebon, Dulac, Rozenberg, Beutler, Tardieu, Abel, Casanova; (JOURNAL ARTICLE)

Nonproliferation. Endgame for the U.S.-Russian Nuclear Cities program.

Stone, Kintisch; (News)

Influenza. Ground the planes during a flu pandemic? Studies disagree.

Enserink; (News)

Vesicle formation at the plasma membrane and trans-Golgi network: the same but different.

McNiven, Thompson; (Journal Article)

IRBs: going too far or not far enough?

Vogt; (Comment, Letter)

Near-threshold inelastic collisions using molecular beams with a tunable velocity.

Gilijamse, Hoekstra, van de Meerakker, Groenenboom, Meijer; (Journal Article)

Infectious disease. Extensively drug-resistant TB gets foothold in South Africa.

Cohen; (News)

Social science. Death in Darfur.

Hagan, Palloni; (Journal Article)

Genomics. Microarray data reproduced, but some concerns remain.

Couzin; (News)

Cell biology. A stressful situation.

Marx; (News)

Nature Methods

Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays.

Kulkarni, Booker, Silver, Friedman, Hong, Perrimon, Mathey-Prevot; (JOURNAL ARTICLE)

Quantum dots go with the flow.

Kaganman; (Journal Article)

In praise of manual high-throughput screening.

Evanko; (Journal Article)

STEDy progress.

Evanko; (Journal Article)

RNA interference on target.

none; (Editorial)

Pushing size to the limit: extreme DNA.

Doerr; (Journal Article)

Nature Biotechnology

Companies eye slice of age-related macular degeneration market.

Waltz; (Journal Article)

Corrigendum: Engineering and characterization of a superfolder green fluorescent protein.

Pe Delacq, Cabantous, Tran, Terwilliger, Waldo; (Journal Article)

Research highlights.

none; (Journal Article)

Making the most of microarrays.

none; (Journal Article)

Using RNA sample titrations to assess microarray platform performance and normalization techniques.

Shippy, Fulmer-Smentek, Jensen, Jones, Wolber, Johnson, Pine, Boysen, Guo, Chudin, Sun, Willey, Thierry-Mieg, Thierry-Mieg, Setterquist, Wilson, Lucas, Novoradovskaya, Papallo, Turpaz, Baker, Warrington, Shi, Herman; (Journal Article)

Recent patent applications in tissue engineering.

none; (Journal Article)

Evaluation of DNA microarray results with quantitative gene expression platforms.

Canales, Luo, Willey, Austermiller, Barbacioru, Boysen, Hunkapiller, Jensen, Knight, Lee, Ma, Maqsodi, Papallo, Peters, Poulter, Ruppel, Samaha, Shi, Yang, Zhang, Goodsaid; (Journal Article)

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

Beausoleil, Villén, Gerber, Rush, Gygi; (JOURNAL ARTICLE)

A framework for the use of genomics data at the EPA.

Dix, Gallagher, Benson, Groskinsky, McClintock, Dearfield, Farland; (Journal Article)

BioXell: an Italian biotech success story?

Sheridan; (Journal Article)

Sequencing errors or SNPs at splice-acceptor guanines in dbSNP?

Platzer, Hiller, Szafranski, Jahn, Hampe, Schreiber, Backofen, Huse; (Journal Article)

Five attributes of a successful manager in a research organization.

Wong; (Journal Article)

Evidence and anecdotes: an analysis of human gene patenting controversies.

Caulfield, Cook-Deegan, Kieff, Walsh; (Journal Article)

Amgen's TPO mimic faces stiff competition.

Lawrence; (Journal Article)

Impact of microarray data quality on genomic data submissions to the FDA.

Frueh; (Journal Article)

Rat toxicogenomic study reveals analytical consistency across microarray platforms.

Guo, Lobenhofer, Wang, Shippy, Harris, Zhang, Mei, Chen, Herman, Goodsaid, Hurban, Phillips, Xu, Deng, Sun, Tong, Dragan, Shi; (JOURNAL ARTICLE)

Performance comparison of one-color and two-color platforms within the Microarray Quality Control (MAQC) project.

Patterson, Lobenhofer, Fulmer-Smentek, Collins, Chu, Bao, Fang, Kawasaki, Hager, Tikhonova, Walker, Zhang, Hurban, de Longueville, Fuscoe, Tong, Shi, Wolfinger; (Journal Article)

Reply to GM sterile mosquitoes-a cautionary note.

none; (Journal Article)

The breeder's dilemma-yield or nutrition?

Morris, Sands; (Journal Article)

New clinical trials policy at FDA.

Vastag; (Journal Article)

Erratum: Alfimeprase to succeed Genentech's alteplase?

Vastag; (Journal Article)

Data quality in genomics and microarrays.

Ji, Davis; (JOURNAL ARTICLE)

News in brief.

none; (Journal Article)

The worm turns for antimicrobial discovery.

Bhavsar, Brown; (Journal Article)

Clinical trial data: to disclose or not to disclose?

Bouchie; (Journal Article)

Data integration gets 'Sloppy'

Almeida, Chen, Gorlitsky, Stanislaus, Aires-de-Sousa, Eleutério, Carriço, Maretzek, Bohn, Chang, Zhang, Mitra, Mills, Wang, Deus; (JOURNAL ARTICLE)

Systems biology, incorporated?

Thiel; (Journal Article)

Biotech R&D goes further afield.

Lawrence; (Journal Article)

The sweet side of biomarker discovery.

Bosques, Raguram, Sasisekharan; (JOURNAL ARTICLE)

Replacing cRNA targets with cDNA reduces microarray cross-hybridization.

Eklund, Turner, Chen, Jensen, Defeo, Kopf-Sill, Szallasi; (JOURNAL ARTICLE)

Artificial sperm and epigenetic reprogramming.

Lucifero, Reik; (Journal Article)

Corrigendum: All in the RNA family.

Davidson; (Journal Article)

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements.

Shi, Reid, Jones, Shippy, Warrington, Baker, Collins, de Longueville, Kawasaki, Lee, Luo, Sun, Willey, Setterquist, Fischer, Tong, Dragan, Dix, Frueh, Goodsaid, Herman, Jensen, Johnson, Lobenhofer, Puri, Scherf, Thierry-Mieg, Wang, Wilson, Wolber, Zhang, Amur, Bao, Barbacioru, Lucas, Bertholet, Boysen, Bromley, Brown, Brunner, Canales, Cao, Cebula, Chen, Cheng, Chu, Chudin, Corson, Corton, Croner, Davies, Davison, Delenstarr, Deng, Dorris, Eklund, Fan, Fang, Fulmer-Smentek, Fuscoe, Gallagher, Ge, Guo, Guo, Hager, Haje, Han, Han, Harbottle, Harris, Hatchwell, Hauser, Hester, Hong, Hurban, Jackson, Ji, Knight, Kuo, Leclerc, Levy, Li, Liu, Liu, Lombardi, Ma, Magnuson, Maqsodi, McDaniel, Mei, Myklebost, Ning, Novoradovskaya, Orr, Osborn, Papallo, Patterson, Perkins, Peters, Peterson, Philips, Pine, Pusztai, Qian, Ren, Rosen, Rosenzweig, Samaha, Schena, Schroth, Shchegrova, Smith, Staedtler, Su, Sun, Szallasi, Tezak, Thierry-Mieg, Thompson, Tikhonova, Turpaz, Vallanat, Van, Walker, Wang, Wang, Wolfinger, Wong, Wu, Xiao, Xie, Xu, Yang, Zhang, Zhong, Zong, Slikker; (JOURNAL ARTICLE)

The dog as a cancer model.

Khanna, Lindblad-Toh, Vail, London, Bergman, Barber, Breen, Kitchell, McNeil, Modiano, Niemi, Comstock, Ostrander, Westmoreland, Withrow; (Journal Article)

Retraction: Identification of genes that function in the TNF-alpha-mediated apoptotic pathway using randomized hybrid ribozyme libraries.

Kawasaki, Onuki, Suyama, Taira; (Journal Article)

The protection racket.

Jacobs; (JOURNAL ARTICLE)

How to stay out of a BIND.

Busa; (Journal Article)

Profile: abe abuchowski.

Katsnelson; (Journal Article)

GM sterile mosquitoes-a cautionary note.

Knols, Hood-Nowotny, Bossin, Franz, Robinson, Mukabana, Kemboi; (Journal Article)

Genome sequence of the bioplastic-producing "Knallgas" bacterium Ralstonia eutropha H16.

Pohlmann, Fricke, Reinecke, Kusian, Liesegang, Cramm, Eitinger, Ewering, Pötter, Schwartz, Strittmatter, Voß, Gottschalk, Steinbüchel, Friedrich, Bowien; (JOURNAL ARTICLE)

Evaluation of external RNA controls for the assessment of microarray performance.

Tong, Lucas, Shippy, Fan, Fang, Hong, Orr, Chu, Guo, Collins, Sun, Wang, Bao, Wolfinger, Shchegrova, Guo, Warrington, Shi; (Journal Article)

Empowering microarrays in the regulatory setting.

Casciano, Woodcock; (JOURNAL ARTICLE)

Can Europe accelerate out of trouble?

none; (Journal Article)

Erratum: Diversifying chemical arrays.

Defrancesco; (Journal Article)

Oversight of US genetic testing laboratories.

Hudson, Murphy, Kaufman, Javitt, Katsanis, Scott; (JOURNAL ARTICLE)

People.

none; (Journal Article)

Why spurning food biotech has become a liability.

Miller, Conko, Kershen; (Journal Article)

Nature Medicine

Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia.

de Jong, Simmons, Thanh, Hien, Smith, Chau, Hoang, Van Vinh Chau, Khanh, Dong, Qui, Van Cam, Ha, Guan, Peiris, Chinh, Hien, Farrar; (JOURNAL ARTICLE)

Nature Genetics

Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase.

Ramirez, Heimbach, Gründemann, Stiller, Hampshire, Cid, Goebel, Mubaidin, Wriekat, Roeper, Al-Din, Hillmer, Karsak, Liss, Woods, Behrens, Kubisch; (JOURNAL ARTICLE)

iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53.

Bergamaschi, Samuels, Sullivan, Zvelebil, Breyssens, Bisso, Del Sal, Syed, Smith, Gasco, Crook, Lu; (JOURNAL ARTICLE)

Nucleosome positions predicted through comparative genomics.

Ioshikhes, Albert, Zanton, Pugh; (JOURNAL ARTICLE)

Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule.

Lalioti, Zhang, Volkman, Kahle, Hoffmann, Toka, Nelson-Williams, Ellison, Flavell, Booth, Lu, Geller, Lifton; (JOURNAL ARTICLE)

Molecular Medicine

Proteomics

Aqueous polymer two-phase systems: Effective tools for plasma membrane proteomics.

Schindler, Nothwang; (JOURNAL ARTICLE)

Chemistry meets proteomics: The use of chemical tagging reactions for MS-based proteomics.

Leitner, Lindner; (JOURNAL ARTICLE)

Advances in plant proteomics.

Chen, Harmon; (JOURNAL ARTICLE)

Proteomic analysis of cancer tissues: Shedding light on carcinogenesis and possible biomarkers.

Kuramitsu, Nakamura; (JOURNAL ARTICLE)

Quintessence from proteomics networks - the HUPO Brain Proteome Project Pilot Studies.

Meyer, Hamacher; (JOURNAL ARTICLE)

In this issue: Proteomics 18/2006.

none; (JOURNAL ARTICLE)

Proteomics as a route to identification of toxicity targets in environmental toxicology.

Dowling, Sheehan; (JOURNAL ARTICLE)

Proteomics and transfusion medicine: Future perspectives.

Queloz, Thadikkaran, Crettaz, Rossier, Barelli, Tissot; (JOURNAL ARTICLE)

Proteomics and metabolomics: The molecular make-up of toxic aromatic pollutant bioremediation.

Singh; (JOURNAL ARTICLE)

Nature Drug Discovery

BMC Bioinformatics

Application of protein structure alignments to iterated hidden Markov model protocols for structure prediction.

Scheeff, Bourne; (JOURNAL ARTICLE)

Scanning sequences after Gibbs sampling to find multiple occurrences of functional elements.

Tharakaraman, Marino-Ramirez, Sheetlin, Landsman, Spouge; (JOURNAL ARTICLE)

Genome-wide DNA polymorphism analyses using VariScan.

Hutter, Vilella, Rozas; (JOURNAL ARTICLE)

Bioinformatics

Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities.

Sanguinetti, Lawrence, Rattray; (JOURNAL ARTICLE)

Protein-RNA interactions: exploring binding patterns with a three-dimensional superposition analysis of high resolution structures.

Morozova, Allers, Myers, Shamoo; (JOURNAL ARTICLE)

Support vector machine learning from heterogeneous data: an empirical analysis using protein sequence and structure.

Lewis, Jebara, Noble; (JOURNAL ARTICLE)

SCAssign: a Sparky extension for the NMR resonance assignment of aliphatic side-chains of uniformly 13C,15N-labeled large proteins.

Zhang, Yang; (JOURNAL ARTICLE)

Augur - a computational pipeline for whole genome microbial surface protein prediction and classification.

Billion, Ghai, Chakraborty, Hain; (JOURNAL ARTICLE)

SPEED: a molecular-evolution-based database of mammalian orthologous groups.

Vallender, Paschall, Malcom, Lahn, Wyckoff; (JOURNAL ARTICLE)

Proc Natl Acad Sci U S A

First-principles, quantum-mechanical simulations of electron solvation by a water cluster.

Herbert, Head-Gordon; (JOURNAL ARTICLE)

Extreme genetic risk for type 1A diabetes.

Aly, Ide, Jahromi, Barker, Fernando, Babu, Yu, Miao, Erlich, Fain, Barriga, Norris, Rewers, Eisenbarth; (JOURNAL ARTICLE)

A therapeutic target for prostate cancer based on angiogenin-stimulated angiogenesis and cancer cell proliferation.

Yoshioka, Wang, Kishimoto, Tsuji, Hu; (JOURNAL ARTICLE)

Testing the importance of p27 degradation by the SCFskp2 pathway in murine models of lung and colon cancer.

Timmerbeul, Garrett-Engele, Kossatz, Chen, Firpo, Grünwald, Kamino, Wilkens, Lehmann, Buer, Geffers, Kubicka, Manns, Porter, Roberts, Malek; (JOURNAL ARTICLE)

The molecular basis for T-type Ca2+ channel inhibition by G protein {beta}2{gamma}2 subunits.

Depuy, Yao, Hu, McIntire, Bidaud, Lory, Rastinejad, Gonzalez, Garrison, Barrett; (JOURNAL ARTICLE)

Self-assembly of receptor/signaling complexes in bacterial chemotaxis.

Wolanin, Baker, Francis, Thomas, Derosier, Stock; (JOURNAL ARTICLE)

A small-molecule inhibitor of type III secretion inhibits different stages of the infectious cycle of Chlamydia trachomatis.

Muschiol, Bailey, Gylfe, Sundin, Hultenby, Bergström, Elofsson, Wolf-Watz, Normark, Henriques-Normark; (JOURNAL ARTICLE)

A mutation in the translation initiation codon of Gata-1 disrupts megakaryocyte maturation and causes thrombocytopenia.

Majewski, Metcalf, Mielke, Krebs, Ellis, Carpinelli, Mifsud, Di Rago, Corbin, Nicola, Hilton, Alexander; (JOURNAL ARTICLE)

Progesterone blocks estrogen-induced DNA synthesis through the inhibition of replication licensing.

Pan, Deng, Pollard; (JOURNAL ARTICLE)

Intracellular IL-1{alpha}-binding proteins contribute to biological functions of endogenous IL-1{alpha} in systemic sclerosis fibroblasts.

Kawaguchi, Nishimagi, Tochimoto, Kawamoto, Katsumata, Soejima, Kanno, Kamatani, Hara; (JOURNAL ARTICLE)

Role of cocaine- and amphetamine-regulated transcript in estradiol-mediated neuroprotection.

Xu, Zhang, Klaus, Young, Koerner, Sheldahl, Hurn, Martínez-Murillo, Alkayed; (JOURNAL ARTICLE)

Alternative inclusion of fibroblast growth factor receptor 2 exon IIIc in Dunning prostate tumors reveals unexpected epithelial mesenchymal plasticity.

Oltean, Sorg, Albrecht, Bonano, Brazas, Dewhirst, Garcia-Blanco; (JOURNAL ARTICLE)

A tropomyosin-related kinase B ligand is required for ERK activation, long-term synaptic facilitation, and long-term memory in Aplysia.

Sharma, Sherff, Stough, Hsuan, Carew; (JOURNAL ARTICLE)

Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis.

Wang, Zukas, Hui, Ricciotti, Puré, Fitzgerald; (JOURNAL ARTICLE)

Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration.

Trowbridge, Scott, Bhatia; (JOURNAL ARTICLE)

A rationally designed agonist antibody fragment that functionally mimics thrombopoietin.

Frederickson, Renshaw, Lin, Smith, Calveley, Springhorn, Johnson, Wang, Su, Shen, Bowdish; (JOURNAL ARTICLE)

The cephalic neural crest exerts a critical effect on forebrain and midbrain development.

Creuzet, Martinez, Le Douarin; (JOURNAL ARTICLE)

Mg2+-RNA interaction free energies and their relationship to the folding of RNA tertiary structures.

Grilley, Soto, Draper; (JOURNAL ARTICLE)

Genome reduction in Leptospira borgpetersenii reflects limited transmission potential.

Bulach, Zuerner, Wilson, Seemann, McGrath, Cullen, Davis, Johnson, Kuczek, Alt, Peterson-Burch, Coppel, Rood, Davies, Adler; (JOURNAL ARTICLE)

Sleep disruption, oxidative stress, and aging: New insights from fruit flies.

Cirelli; (JOURNAL ARTICLE)

Continuous up-regulation of heat shock proteins in larvae, but not adults, of a polar insect.

Rinehart, Hayward, Elnitsky, Sandro, Lee, Denlinger; (JOURNAL ARTICLE)

Solution structure of the complex between poxvirus-encoded CC chemokine inhibitor vCCI and human MIP-1{beta}

Zhang, Derider, McCornack, Jao, Isern, Ness, Moyer, Liwang; (JOURNAL ARTICLE)

Secondary lymphoid tissue chemokine (SLC/CCL21)/CCR7 signaling regulates fibrocytes in renal fibrosis.

Sakai, Wada, Yokoyama, Lipp, Ueha, Matsushima, Kaneko; (JOURNAL ARTICLE)

Rapid high-yield expression of full-size IgG antibodies in plants coinfected with noncompeting viral vectors.

Giritch, Marillonnet, Engler, van Eldik, Botterman, Klimyuk, Gleba; (JOURNAL ARTICLE)

Transcriptional activation by EBV nuclear antigen 1 is essential for the expression of EBV's transforming genes.

Altmann, Pich, Ruiss, Wang, Sugden, Hammerschmidt; (JOURNAL ARTICLE)

Predicting the epidemiological impact of antiretroviral allocation strategies in KwaZulu-Natal: The effect of the urban-rural divide.

Wilson, Kahn, Blower; (JOURNAL ARTICLE)

Phoretic nest parasites use sexual deception to obtain transport to their host's nest.

Saul-Gershenz, Millar; (JOURNAL ARTICLE)

Activation of NF-{kappa}B by the intracellular expression of NF-{kappa}B-inducing kinase acts as a powerful vaccine adjuvant.

Andreakos, Williams, Wales, Foxwell, Feldmann; (JOURNAL ARTICLE)

Crocidolite asbestos and SV40 are cocarcinogens in human mesothelial cells and in causing mesothelioma in hamsters.

Kroczynska, Cutrone, Bocchetta, Yang, Elmishad, Vacek, Ramos-Nino, Mossman, Pass, Carbone; (JOURNAL ARTICLE)

The nucleotide-binding site of bacterial translation initiation factor 2 (IF2) as a metabolic sensor.

Milon, Tischenko, Tomsic, Caserta, Folkers, La Teana, Rodnina, Pon, Boelens, Gualerzi; (JOURNAL ARTICLE)

Codon-usage bias versus gene conversion in the evolution of yeast duplicate genes.

Lin, Byrnes, Hwang, Li; (JOURNAL ARTICLE)

Central peptidergic ensembles associated with organization of an innate behavior.

Kim, Zitnan, Cho, Schooley, Mizoguchi, Adams; (JOURNAL ARTICLE)

Efficiency of carcinogenesis with and without a mutator mutation.

Beckman, Loeb; (JOURNAL ARTICLE)

Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival.

Egger, Jeong, Escobar, Cortez, Li, Saito, Yoo, Jones, Liang; (JOURNAL ARTICLE)

Pathogenesis and treatment of autosomal-dominant nephrogenic diabetes insipidus caused by an aquaporin 2 mutation.

Sohara, Rai, Yang, Uchida, Nitta, Horita, Ohno, Harada, Sasaki, Uchida; (JOURNAL ARTICLE)

A phosphoryl transfer intermediate in the GTPase reaction of Ras in complex with its GTPase-activating protein.

Kötting, Blessenohl, Suveyzdis, Goody, Wittinghofer, Gerwert; (JOURNAL ARTICLE)

The effect of anticipation and the specificity of sex differences for amygdala and hippocampus function in emotional memory.

Mackiewicz, Sarinopoulos, Cleven, Nitschke; (JOURNAL ARTICLE)

QnAs with Karl Mahlburg.

Nuzzo; (Journal Article)

Identifying regulatory mechanisms using individual variation reveals key role for chromatin modification.

Lee, Pe'er, Dudley, Church, Koller; (JOURNAL ARTICLE)

The quantum MacMahon Master Theorem.

Garoufalidis, Lê, Zeilberger; (JOURNAL ARTICLE)

The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response.

Zhou, Liu, Back, Clark, Peisach, Xu, Kaufman; (JOURNAL ARTICLE)

Prolactin/growth hormone-derived antiangiogenic peptides highlight a potential role of tilted peptides in angiogenesis.

Nguyen, Tabruyn, Lins, Lion, Cornet, Lair, Rentier-Delrue, Brasseur, Martial, Struman; (JOURNAL ARTICLE)

A conserved role for a GATA transcription factor in regulating epithelial innate immune responses.

Shapira, Hamlin, Rong, Chen, Ronen, Tan; (JOURNAL ARTICLE)

Cross-protective immunity can account for the alternating epidemic pattern of dengue virus serotypes circulating in Bangkok.

Adams, Holmes, Zhang, Mammen, Nimmannitya, Kalayanarooj, Boots; (JOURNAL ARTICLE)

Mechanisms of uropathogenic Escherichia coli persistence and eradication from the urinary tract.

Mysorekar, Hultgren; (JOURNAL ARTICLE)

The herpesvirus glycoproteins B and H*L are sequentially recruited to the receptor-bound gD to effect membrane fusion at virus entry.

Gianni, Forghieri, Campadelli-Fiume; (JOURNAL ARTICLE)

Protein surface hydration mapped by site-specific mutations.

Qiu, Kao, Zhang, Yang, Wang, Stites, Zhong, Zewail; (JOURNAL ARTICLE)

Rapid nongenomic actions of thyroid hormone.

Hiroi, Kim, Ying, Furuya, Huang, Simoncini, Noma, Ueki, Nguyen, Scanlan, Moskowitz, Cheng, Liao; (JOURNAL ARTICLE)

Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion.

Frey, Rits-Volloch, Zhang, Schooley, Chen, Harrison; (JOURNAL ARTICLE)

{beta}-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity.

Quack, Rump, Gerke, Walther, Vinke, Vonend, Grunwald, Sellin; (JOURNAL ARTICLE)

Cropland expansion changes deforestation dynamics in the southern Brazilian Amazon.

Morton, Defries, Shimabukuro, Anderson, Arai, Del Bon Espirito-Santo, Freitas, Morisette; (JOURNAL ARTICLE)

Differential microarray analysis of Drosophila mushroom body transcripts using chemical ablation.

Kobayashi, Michaut, Ino, Honjo, Nakajima, Maruyama, Mochizuki, Ando, Ghangrekar, Takahashi, Saigo, Ueda, Gehring, Furukubo-Tokunaga; (JOURNAL ARTICLE)

Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer.

Gao, Ouyang, Banach-Petrosky, Gerald, Shen, Abate-Shen; (JOURNAL ARTICLE)

Quantitative phase tomography of Arabidopsis seeds reveals intercellular void network.

Cloetens, Mache, Schlenker, Lerbs-Mache; (JOURNAL ARTICLE)

Influenza A virus NS1 protein binds p85{beta} and activates phosphatidylinositol-3-kinase signaling.

Hale, Jackson, Chen, Lamb, Randall; (JOURNAL ARTICLE)

Self-assembled single-crystal silicon circuits on plastic.

Stauth, Parviz; (JOURNAL ARTICLE)

Cytoskeletal polymer networks: The molecular structure of cross-linkers determines macroscopic properties.

Wagner, Tharmann, Haase, Fischer, Bausch; (JOURNAL ARTICLE)

Identification of Clostridium difficile toxin B cardiotoxicity using a zebrafish embryo model of intoxication.

Hamm, Voth, Ballard; (JOURNAL ARTICLE)

Ca2+/calmodulin-dependent protein kinase II (CaMKII) is activated by calmodulin with two bound calciums.

Shifman, Choi, Mihalas, Mayo, Kennedy; (JOURNAL ARTICLE)

AL-57, a ligand-mimetic antibody to integrin LFA-1, reveals chemokine-induced affinity up-regulation in lymphocytes.

Shimaoka, Kim, Cohen, Yang, Astrof, Peer, Salas, Ferrand, Springer; (JOURNAL ARTICLE)

The transcriptome of human oocytes.

Kocabas, Crosby, Ross, Otu, Beyhan, Can, Tam, Rosa, Halgren, Lim, Fernandez, Cibelli; (JOURNAL ARTICLE)

Lakes of liquid CO2 in the deep sea.

Nealson; (JOURNAL ARTICLE)

A molecular mechanism for osmolyte-induced protein stability.

Street, Bolen, Rose; (JOURNAL ARTICLE)

Reconstitution of full-round uridine-deletion RNA editing with three recombinant proteins.

Kang, Gao, Rogers, Falick, Zhou, Simpson; (JOURNAL ARTICLE)

Evolving resistance to obesity in an insect.

Warbrick-Smith, Behmer, Lee, Raubenheimer, Simpson; (JOURNAL ARTICLE)

Forced and unforced ocean temperature changes in Atlantic and Pacific tropical cyclogenesis regions.

Santer, Wigley, Gleckler, Bonfils, Wehner, Achutarao, Barnett, Boyle, Brüggemann, Fiorino, Gillett, Hansen, Jones, Klein, Meehl, Raper, Reynolds, Taylor, Washington; (JOURNAL ARTICLE)

Diversity of zebrafish peripheral oscillators revealed by luciferase reporting.

Kaneko, Hernandez-Borsetti, Cahill; (JOURNAL ARTICLE)

Ancestral reconstruction of the ligand-binding pocket of Family C G protein-coupled receptors.

Kuang, Yao, Maclean, Wang, Hampson, Chang; (JOURNAL ARTICLE)

Molecular switch for alternative conformations of the HIV-1 V3 region: Implications for phenotype conversion.

Rosen, Sharon, Quadt-Akabayov, Anglister; (JOURNAL ARTICLE)

Functional organization of perisylvian activation during presentation of sentences in preverbal infants.

Dehaene-Lambertz, Hertz-Pannier, Dubois, Mériaux, Roche, Sigman, Dehaene; (JOURNAL ARTICLE)

N Engl J Med

Fingolimod and sphingosine-1-phosphate--modifiers of lymphocyte migration.

Massberg, von Andrian; (Comment, Journal Article)

Idiopathic short stature.

Rapaport; (Comment, Letter)

Case records of the Massachusetts General Hospital. Case 28-2006. A 59-year-old man with masses in both kidneys.

McDougal, Tolkoff-Rubin, Michaelson, Mueller, Braaten; (Clinical Conference, Journal Article)

Fluid-management strategies in acute lung injury.

Amaral, Amado; (Comment, Letter)

Echinocandins for candidemia in adults without neutropenia.

Bennett; (Journal Article)

Paclitaxel-eluting versus uncoated stents in primary percutaneous coronary intervention.

Laarman, Suttorp, Dirksen, van Heerebeek, Kiemeneij, Slagboom, van der Wieken, Tijssen, Rensing, Patterson; (Comment, Journal Article)

Cost-effectiveness of HIV treatment in resource-poor settings--the case of Côte d'Ivoire.

Goldie, Yazdanpanah, Losina, Weinstein, Anglaret, Walensky, Hsu, Kimmel, Holmes, Kaplan, Freedberg; (Journal Article)

Thyroxine in goiter, H. pylori infection, and gastritis.

Taylor, Sisson, Harris; (Comment, Journal Article)

Cyclophosphamide in scleroderma lung disease.

Andreu, Silva; (Comment, Letter)

Chemotherapy with preoperative radiotherapy in rectal cancer.

Bosset, Collette, Calais, Mineur, Maingon, Radosevic-Jelic, Daban, Bardet, Beny, Ollier; (Journal Article)

Sirolimus-eluting versus uncoated stents in acute myocardial infarction.

Spaulding, Henry, Teiger, Beatt, Bramucci, Carrié, Slama, Merkely, Erglis, Margheri, Varenne, Cebrian, Stoll, Snead, Bode; (Journal Article)

Drug-eluting stents in acute myocardial infarction.

Van de Werf; (Comment, Editorial)

Message from Toronto--deliver AIDS treatment and prevention.

Steinbrook; (Journal Article)

Fluid-management strategies in acute lung injury.

Schuller, Schuster; (Comment, Letter)

Oral fingolimod (FTY720) for relapsing multiple sclerosis.

Kappos, Antel, Comi, Montalban, O'Connor, Polman, Haas, Korn, Karlsson, Radue; (Journal Article)

Male urethral catheterization.

Canes; (Comment, Letter)

Cyclophosphamide in scleroderma lung disease.

Kuschner; (Comment, Letter)

Global health--the Gates-Buffett effect.

Okie; (Journal Article)

Cyclophosphamide in scleroderma lung disease.

Sullivan, McSweeney, Nash; (Comment, Letter)

A critical new pathway for toxin secretion?

Yahr; (Journal Article)

Images in clinical medicine. Elevated jugular venous pressure.

Györik, Menafoglio; (Journal Article)

Fluid-management strategies in acute lung injury.

Morizio, Kupfer, Tessler; (Comment, Letter)

Images in clinical medicine. Radiographic appearance of lanthanum.

Cerny, Kunzendorf; (Journal Article)

Thyroxine in goiter, H. pylori infection, and gastritis.

Dietrich, Boehm; (Comment, Letter)

Patient-specific dendritic-cell vaccines for metastatic melanoma.

Dillman, Selvan, Schiltz; (Letter)

J Natl Cancer Inst

Lancet

Incubation period of human prion disease.

Focosi; (Comment, Letter)

Iraq's health requires continued funding commitment.

Bristol; (News)

Efficacy and tolerability of dapoxetine in treatment of premature ejaculation: an integrated analysis of two double-blind, randomised controlled trials.

Pryor, Althof, Steidle, Rosen, Hellstrom, Shabsigh, Miloslavsky, Kell; (Journal Article)

Novel strategies for stimulating erythropoiesis and potential new treatments for anaemia.

Macdougall, Eckardt; (Journal Article)

The Trivacan study.

Nüesch; (Comment, Letter)

Drug bulletins: independent information for global use.

Olsson, Pal; (Journal Article)

Effective implementation of the Human Tissue Act.

none; (Editorial)

Medical therapy for premature ejaculation.

Montorsi, Salonia; (Comment, Journal Article)

Dissent over harm reduction for tobacco.

Gray, Henningfield; (Journal Article)

Assessing the health implications of Nepal's ceasefire.

Collins; (News)

The Trivacan study.

Maggiolo, Ripamonti, Suter; (Comment, Letter)

A kidney non-transplantable.

Tondolo, Nanni, Citterio, Di Stasi, Castagneto; (Journal Article)

Bridging the divide: global lessons from evidence-based health policy in Mexico.

Frenk; (Journal Article)

Vulvar ulceration with an unexpected underlying cause.

Oonk, van der Ploeg, van Lonkhuijzen; (Journal Article)

Incubation period of human prion disease.

Klitzman; (Comment, Letter)

Naeema Al Gasseer: defending public health in Iraq.

Loewenberg; (News)

Infant mortality among Australian Aboriginals - Authors' reply.

Freemantle, Read, de Klerk, McAullay, Anderson, Stanley; (LETTER)

Incubation period of human prion disease - Author's reply.

Collinge, Alpers; (LETTER)

The Health Systems Action Network: a promising start.

none; (Editorial)

Universal prenatal herpes screening is a bad idea in pregnancy.

Urato, Caughey; (Journal Article)

Incubation period of human prion disease.

Nishiura, Leary; (Comment, Letter)

Financial deficits in the health services of the UK and Hungary.

Boncz, Sebestyén; (Comment, Letter)

Incubation period of human prion disease.

Boelle, Valleron; (Comment, Letter)

Prevention of mortality from hepatitis B and hepatitis C.

Schiff; (Comment, Journal Article)

Alcohol abuse in Poland.

Czupryniak, Loba; (Comment, Letter)

Causes of death after diagnosis of hepatitis B or hepatitis C infection: a large community-based linkage study.

Amin, Law, Bartlett, Kaldor, Dore; (Journal Article)

Chikungunya re-emergence: possible mechanisms.

Mishra, Ratho; (Comment, Letter)

Serial interviews for patients with progressive diseases.

Murray, Sheikh; (Journal Article)

Does the metabolic syndrome help to select patients requiring high statin dose?

Scheen; (Comment, Journal Article)

Recognising the rights of individuals with disabilities.

none; (Editorial)

The Trivacan study - Authors' reply.

Danel, Moh, Sorho, Gabillard, Anglaret; (LETTER)

Reduction of low-density lipoprotein cholesterol in patients with coronary heart disease and metabolic syndrome: analysis of the Treating to New Targets study.

Deedwania, Barter, Carmena, Fruchart, Grundy, Haffner, Kastelein, LaRosa, Schachner, Shepherd, Waters; (Journal Article)

Infant mortality among Australian Aboriginals.

Santow; (Comment, Letter)

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