Nature

Control and detection of chemical reactions in microfluidic systems.

DeMello; (Journal Article)

Psychophysics: reply: Putting plaids in perspective.

Farell; (Journal Article)

Rad54 protein promotes branch migration of Holliday junctions.

Bugreev, Mazina, Mazin; (JOURNAL ARTICLE)

... as government sets sights on an 'innovation economy'.

Xuewen; (Journal Article)

Quest for seed immortality is mission impossible.

Graner, Börner; (Comment, Letter)

Mechanism limiting centrosome duplication to once per cell cycle.

Tsou, Stearns; (JOURNAL ARTICLE)

100 and 50 years ago.

none; (Journal Article)

Protein flexibility acclimatizes photosynthetic energy conversion to the ambient temperature.

Shlyk-Kerner, Samish, Kaftan, Holland, Maruthi Sai, Kless, Scherz; (JOURNAL ARTICLE)

Coupling strength of charge carriers to spin fluctuations in high-temperature superconductors.

Carbotte, Schachinger, Basov; (Journal Article)

Taking the horror out of shocks.

Freeman; (Journal Article)

A genomic code for nucleosome positioning.

Segal, Fondufe-Mittendorf, Chen, Thåström, Field, Moore, Wang, Widom; (JOURNAL ARTICLE)

Microfluidic diagnostic technologies for global public health.

Yager, Edwards, Fu, Helton, Nelson, Tam, Weigl; (Journal Article)

Cancer biology: A game of subversion.

Passegué; (JOURNAL ARTICLE)

A low fraction of nitrogen in molecular form in a dark cloud.

Maret, Bergin, Lada; (Journal Article)

No dirty tricks in merger ballot.

Bobo; (Journal Article)

Hungary: academy needs more than internal reform.

Szabo; (Comment, Letter)

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

Krivtsov, Twomey, Feng, Stubbs, Wang, Faber, Levine, Wang, Hahn, Gilliland, Golub, Armstrong; (JOURNAL ARTICLE)

Methane drizzle on Titan.

Tokano, McKay, Neubauer, Atreya, Ferri, Fulchignoni, Niemann; (Journal Article)

Taxonomists are an endangered species in Europe.

Buyck; (Journal Article)

Bombing of embassy bolsters support for science in China...

Xuewen; (Journal Article)

Binding of double-strand breaks in DNA by human Rad52 protein.

Van Dyck, Stasiak, Stasiak, West; (Journal Article)

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17.

Baker, Mackenzie, Pickering-Brown, Gass, Rademakers, Lindholm, Snowden, Adamson, Sadovnick, Rollinson, Cannon, Dwosh, Neary, Melquist, Richardson, Dickson, Berger, Eriksen, Robinson, Zehr, Dickey, Crook, McGowan, Mann, Boeve, Feldman, Hutton; (JOURNAL ARTICLE)

New in paperback.

none; (Journal Article)

Design flaws.

Bonner; (Journal Article)

US Senate restores proposed cut in science budgets.

Macilwain; (Journal Article)

Border control at the frontiers of science.

Mermin; (Journal Article)

Lab on a chip: a little goes a long way.

Hogan; (News)

News in brief.

none; (JOURNAL ARTICLE)

US university finds use for Air Force research reactor.

Dalton; (Journal Article)

Scaling and the design of miniaturized chemical-analysis systems.

Janasek, Franzke, Manz; (Journal Article)

Norm-based face encoding by single neurons in the monkey inferotemporal cortex.

Leopold, Bondar, Giese; (JOURNAL ARTICLE)

Semiconductor physics: magnetic manipulations.

Samarth; (Comment, News)

errata Selective inhibition of cocaine-seeking behaviour by a partial dopamine D(3) receptor agonist.

Pilla, Perachon, Sautel, Garrido, Mann, Wermuth, Schwartz, Everitt, Sokoloff; (Journal Article)

Climatology: extremes in the Indian ocean.

Anderson; (Journal Article)

Cell biology: Polarity bites.

Fehon; (JOURNAL ARTICLE)

The lure of stem-cell lines.

none; (News)

US warms to carbon sequestration research.

Dalton; (Journal Article)

A long week in stem-cell politics...

Wadman, Abbott; (News)

Survey finds deep insularity among Japanese scientists.

Saegusa; (Journal Article)

A timely boost to research on carbon sequestration.

none; (Journal Article)

German museums face cuts.

Schiermeier; (Journal Article)

Celebratory pictures from Subaru.

Saegusa; (Journal Article)

Balancing the Earth's accounts.

James, Gaston, Balmford; (Journal Article)

Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-gamma and PTEN.

Zhao, Song, Pu, Wada, Reid, Tai, Wang, Guo, Walczysko, Gu, Sasaki, Suzuki, Forrester, Bourne, Devreotes, McCaig, Penninger; (Journal Article)

Up the river without a paddle?

Moore; (Journal Article)

Atom-by-atom substitution of Mn in GaAs and visualization of their hole-mediated interactions.

Kitchen, Richardella, Tang, Flatté, Yazdani; (Journal Article)

High-temperature superconductivity: Electrons pair themselves.

Orenstein; (Journal Article)

Cells on chips.

El-Ali, Sorger, Jensen; (Journal Article)

UK universities look to enterprise.

Loder; (Journal Article)

From horsehair to lightning rods.

Heilbron; (Journal Article)

Developmental biology: the hole picture.

Mostov, Martin-Belmonte; (Comment, Letter)

Key contributor.

none; (JOURNAL ARTICLE)

Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21.

Cruts, Gijselinck, van der Zee, Engelborghs, Wils, Pirici, Rademakers, Vandenberghe, Dermaut, Martin, van Duijn, Peeters, Sciot, Santens, De Pooter, Mattheijssens, Van den Broeck, Cuijt, Vennekens, De Deyn, Kumar-Singh, Van Broeckhoven; (JOURNAL ARTICLE)

Widespread active detachment faulting and core complex formation near 13 degrees N on the Mid-Atlantic Ridge.

Smith, Cann, Escartín; (Journal Article)

Diary of a weed.

Trewavas; (Journal Article)

Tribosphenic mammal from the North American Early Cretaceous.

Cifelli; (Journal Article)

Developmental neurobiology: a destructive switch for neurons.

Jackson; (Comment, News)

Research highlights.

none; (JOURNAL ARTICLE)

Carbon credits for the Joneses.

Giles; (News)

Sidelines.

none; (JOURNAL ARTICLE)

Biophysics: Fungus punches its way in.

Money; (Journal Article)

Nigeria ready for huge science spend.

Giles; (News)

Lab on a chip.

Daw, Finkelstein; (Journal Article)

Playing the numbers game.

Colquhoun; (Journal Article)

Portugal's science plots its future.

Bosch; (Journal Article)

How head-hunters track down the winners for science's top jobs.

Goddard; (Journal Article)

Planetary science: Titan's exotic weather.

Griffith; (Comment, News)

Abstractions.

none; (JOURNAL ARTICLE)

Break with tradition.

Jayaraman; (Journal Article)

Golden year.

Teper; (Journal Article)

The body bared.

none; (Journal Article)

Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology.

Kim, Sung, Ceglia, Lee, Ahn, Halford, Kim, Kwak, Park, Ho Ryu, Schenck, Bardoni, Scott, Nairn, Greengard; (JOURNAL ARTICLE)

Astronomy: revealing flares.

Tyson; (News)

E-commerce is a gas.

none; (Journal Article)

Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity.

Gross, Gewies, Finger, Schäfer, Sparwasser, Peschel, Förster, Ruland; (JOURNAL ARTICLE)

Hungary: academy is not obsolete or discriminatory.

Fábri; (Comment, Letter)

Correction.

none; (JOURNAL ARTICLE)

In brief.

none; (JOURNAL ARTICLE)

No place for secrets in scientific research.

Saper; (Comment, Letter)

Spatial control of actin organization at adherens junctions by a synaptotagmin-like protein.

Pilot, Philippe, Lemmers, Lecuit; (JOURNAL ARTICLE)

DNA overwinds when stretched.

Gore, Bryant, Nöllmann, Le, Cozzarelli, Bustamante; (JOURNAL ARTICLE)

Snapshots of tRNA sulphuration via an adenylated intermediate.

Numata, Ikeuchi, Fukai, Suzuki, Nureki; (Journal Article)

Daedalus: Fertile competition.

Jones; (Journal Article)

Bird flu: on border patrol.

Check; (News)

50 & 100 years ago.

none; (JOURNAL ARTICLE)

Protein folding: inside the cage.

Ellis; (News)

Let's replicate.

none; (Editorial)

The origins and the future of microfluidics.

Whitesides; (Journal Article)

A ubiquitous thermoacidophilic archaeon from deep-sea hydrothermal vents.

Reysenbach, Liu, Banta, Beveridge, Kirshtein, Schouten, Tivey, Von Damm, Voytek; (Journal Article)

Structure of the catalytic domain of the hepatitis C virus NS2-3 protease.

Lorenz, Marcotrigiano, Dentzer, Rice; (JOURNAL ARTICLE)

Coupled ocean-atmosphere dynamics in the Indian Ocean during 1997-98.

Webster, Moore, Loschnigg, Leben; (Journal Article)

Still not alert. Tsunami preparations in the Indian Ocean remain inadequate.

none; (Editorial)

And some big steps for science.

Burns; (Journal Article)

Making the paper: Antonio lavarone.

none; (JOURNAL ARTICLE)

A dipole mode in the tropical Indian Ocean.

Saji, Goswami, Vinayachandran, Yamagata; (Journal Article)

Future lab-on-a-chip technologies for interrogating individual molecules.

Craighead; (Journal Article)

Reclusion to be discouraged.

none; (Journal Article)

The devil is in the distance.

Paczynski; (Journal Article)

The trouble with replication.

Giles; (News)

Methane storms on Saturn's moon Titan.

Hueso, Sánchez-Lavega; (Journal Article)

Wildlife caught in crossfire of US immigration battle.

Marris; (News)

Developing optofluidic technology through the fusion of microfluidics and optics.

Psaltis, Quake, Yang; (Journal Article)

Market watch.

none; (JOURNAL ARTICLE)

Oldest playable musical instruments found at Jiahu early Neolithic site in China.

Zhang, Harbottle, Wang, Kong; (Journal Article)

A distance to the galaxy NGC4258 from observations of Cepheid variable stars.

Maoz, Newman, Ferrarese, Stetson, Zepf, Davis, Freedman, Madore; (Journal Article)

Come veto or high water.

none; (Editorial)


Science

HIV/AIDS: Latin America & Caribbean. The Caribbean.

Cohen; (News)

HIV/AIDS: Latin America & Caribbean. Puerto Rico: ample monkeys and money nurture robust research.

Cohen; (News)

HIV/AIDS: Latin America & Caribbean. Honduras: why so high? A knotty story.

Cohen; (News)

HIV/AIDS: Latin America & Caribbean. Mexico & Central America.

Cohen; (News)

Multiple phosphorylation sites confer reproducibility of the rod's single-photon responses.

Doan, Mendez, Detwiler, Chen, Rieke; (Journal Article)

CYK-4/GAP Provides a Localized Cue to Initiate Anteroposterior Polarity upon Fertilization.

Jenkins, Saam, Mango; (JOURNAL ARTICLE)

HIV/AIDS: Latin America & Caribbean. Brazil: free drugs does not equal quality care.

Cohen; (News)

HIV/AIDS: Latin America & Caribbean. Peru: universal access: more goal than reality.

Cohen; (News)

Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice.

Weisstaub, Zhou, Lira, Lambe, González-Maeso, Hornung, Sibille, Underwood, Itohara, Dauer, Ansorge, Morelli, Mann, Toth, Aghajanian, Sealfon, Hen, Gingrich; (Journal Article)

Confidentiality in genome research.

Lin, Altman, Owen; (Comment, Letter)

HIV/AIDS: Latin America & Caribbean. Overview: the overlooked epidemic.

Cohen; (News)

Biomedical research. States, foundations lead the way after Bush vetoes stem cell bill.

Holden; (News)

Agricultural research. Consortium aims to supercharge rice photosynthesis.

Normile; (News)

Immunology. Mast cells defang snake and bee venom.

Marx; (Comment, News)

Neurodegenerative disease. From cycad flour, a new suspect emerges.

Miller; (News)

How and when was wild wheat domesticated?

Hartmann, Kislev, Weiss; (Comment, Historical Article, Letter)

Another Nail in the Plume Coffin?

McNutt; (JOURNAL ARTICLE)

Cell signaling. Protein kinases seek close encounters with active genes.

Edmunds, Mahadevan; (Comment, Journal Article)

Mast cells can enhance resistance to snake and honeybee venoms.

Metz, Piliponsky, Chen, Lammel, Abrink, Pejler, Tsai, Galli; (Journal Article)

Infrastructure. Can grid computing help us work together?

Clery; (News)

Name dropping on decapods.

Martin; (Letter)

2007 U.S. budget. NIH prepares for lean budget after Senate vote.

Couzin, Kaiser; (News)

HIV/AIDS: Latin America & Caribbean. Dominican Republic: the sun. The sand. The sex.

Cohen; (News)

30,000 years of cosmic dust in Antarctic ice.

Winckler, Fischer; (Journal Article)

Meteorology. Rivers in the sky are flooding the world with tropical waters.

Kerr; (News)

Atmosphere. What drives the ice age cycle?

Paillard; (Comment, Journal Article)

Professional development. Who is responsible for preparing science teachers?

Otero, Finkelstein, McCray, Pollock; (Journal Article)

HIV/AIDS: Latin America & Caribbean. Puerto Rico: rich port, poor port.

Cohen; (News)

Second-harmonic generation from magnetic metamaterials.

Klein, Enkrich, Wegener, Linden; (Journal Article)

Neurodegenerative disease. Guam's deadly stalker: on the loose worldwide?

Miller; (News)

HIV/AIDS: Latin America & Caribbean. Dominican Republic: a sour taste on the sugar plantations.

Cohen; (News)

HIV/AIDS: Latin America & Caribbean. Mexico: land of extremes: prevention and care range from bold to bleak.

Cohen; (News)

HIV/AIDS: Latin America & Caribbean. Mexico: prevention programs target migrants.

Cohen; (News)

HIV/AIDS: Latin America & Caribbean. Honduras: mission possible: integrating the church with HIV/AIDS efforts.

Cohen; (News)

Learning to Live With HIV.

Roberts, Cohen; (JOURNAL ARTICLE)

Extinction risk and conservation priorities.

Miller, Rodríguez, Aniskowicz-Fowler, Bambaradeniya, Boles, Eaton, Gärdenfors, Keller, Molur, Walker, Pollock; (Letter)

Molecular biology. Self-correcting messages.

Cramer; (Comment, Journal Article)

HIV/AIDS: Latin America & Caribbean. Argentina: up in smoke: epidemic changes course.

Cohen; (News)

Climate change. Politicians attack, but evidence for global warming doesn't wilt.

Kerr; (News)

Activated signal transduction kinases frequently occupy target genes.

Pokholok, Zeitlinger, Hannett, Reynolds, Young; (Journal Article)

HIV/AIDS: Latin America & Caribbean. Guatemala: struggling to deliver on promises and assess HIV's spread.

Cohen; (News)

HIV/AIDS: Latin America & Caribbean. South America.

Cohen; (News)

Intellectual property. U.S. wants to curtail add-on patents to reduce backlog.

Kintisch; (News)

HIV/AIDS: Latin America & Caribbean. HAITI: making headway under hellacious circumstances.

Cohen; (News)

Superfluidity of Grain Boundaries and Supersolid Behavior.

Sasaki, Ishiguro, Caupin, Maris, Balibar; (JOURNAL ARTICLE)

Twenty-five years of HIV/AIDS.

Fauci; (Editorial)

Questions about mass spectrometry data.

Deng; (Comment, Letter)

Climate change. Can we detect trends in extreme tropical cyclones?

Landsea, Harper, Hoarau, Knaff; (Journal Article)

Transcriptional repression distinguishes somatic from germ cell lineages in a plant.

Haerizadeh, Singh, Bhalla; (Journal Article)

Origins of HIV and the evolution of resistance to AIDS.

Heeney, Dalgleish, Weiss; (Journal Article)

Computer science. New life for neural networks.

Cottrell; (Comment, Journal Article)

HIV/AIDS: Latin America & Caribbean. Brazil: ten years after.

Cohen; (News)

Water projects. U.S. Senate calls for external reviews of big federal digs.

Stokstad; (News)

Volcanism in Response to Plate Flexure.

Hirano, Takahashi, Yamamoto, Abe, Ingle, Kaneoka, Hirata, Kimura, Ishii, Ogawa, Machida, Suyehiro; (JOURNAL ARTICLE)

Physics. A more precise fine structure constant.

Kleppner; (Journal Article)

HIV/AIDS: Latin America & Caribbean. Belize: taking it to the streets.

Cohen; (News)

Reducing the dimensionality of data with neural networks.

Hinton, Salakhutdinov; (Journal Article)

Genome Sequence Diversity and Clues to the Evolution of Variola (Smallpox) Virus.

Esposito, Sammons, Frace, Osborne, Olsen-Rasmussen, Zhang, Govil, Damon, Kline, Laker, Li, Smith, Meyer, Leduc, Wohlhueter; (JOURNAL ARTICLE)

Transcript-assisted transcriptional proofreading.

Zenkin, Yuzenkova, Severinov; (Journal Article)

CFCs and the size of the ozone hole.

Towe; (Letter)

HIV/AIDS: Latin America & Caribbean. Peru: a new nexus for HIV/AIDS research.

Cohen; (News)


Nature Methods

Removal of a time barrier for high-resolution multidimensional NMR spectroscopy.

Jaravine, Ibraghimov, Yu Orekhov; (Journal Article)

The charged sialic acid exhibits its power again: a new high-throughput screening technology.

Wang; (Journal Article)

A unique and universal molecular barcode array.

Pierce, Fung, Jaramillo, Chu, Davis, Nislow, Giaever; (Journal Article)

Feeder-independent culture of human embryonic stem cells.

Ludwig, Bergendahl, Levenstein, Yu, Probasco, Thomson; (JOURNAL ARTICLE)

Helping cells to tell a colorful tale.

Eisenstein; (Journal Article)

Chemical labeling strategies for cell biology.

Marks, Nolan; (Journal Article)

A comprehensive library of fluorescent transcriptional reporters for Escherichia coli.

Zaslaver, Bren, Ronen, Itzkovitz, Kikoin, Shavit, Liebermeister, Surette, Alon; (Journal Article)

Efficient site-specific integration in Plasmodium falciparum chromosomes mediated by mycobacteriophage Bxb1 integrase.

Nkrumah, Muhle, Moura, Ghosh, Hatfull, Jacobs, Fidock; (Journal Article)

High-throughput screening methodology for the directed evolution of glycosyltransferases.

Aharoni, Thieme, Chiu, Buchini, Lairson, Chen, Strynadka, Wakarchuk, Withers; (Journal Article)

An improved mRFP1 adds red to bimolecular fluorescence complementation.

Jach, Pesch, Richter, Frings, Uhrig; (Journal Article)

Enrichment of regulatory CD4(+)CD25(+) T cells by inhibition of phospholipase D signaling.

Singh, Seki, Takami, Baban, Chandler, Khosravi, Zheng, Takezaki, Lee, Mellor, Bollag, Iwashima; (Journal Article)


Nature Biotechnology

Trendspotting: a shift in intellectual property focus.

Anderegg, Thayer, Williams; (Journal Article)


Nature Medicine

A potential molecular mechanism for hypersensitivity caused by formalin-inactivated vaccines.

Moghaddam, Olszewska, Wang, Tregoning, Helson, Sattentau, Openshaw; (JOURNAL ARTICLE)

Connexin37 protects against atherosclerosis by regulating monocyte adhesion.

Wong, Christen, Roth, Chadjichristos, Derouette, Foglia, Chanson, Goodenough, Kwak; (JOURNAL ARTICLE)

Cardiotoxicity of the cancer therapeutic agent imatinib mesylate.

Kerkelä, Grazette, Yacobi, Iliescu, Patten, Beahm, Walters, Shevtsov, Pesant, Clubb, Rosenzweig, Salomon, Van Etten, Alroy, Durand, Force; (JOURNAL ARTICLE)

Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression.

Bandyopadhyay, Zhan, Chaudhuri, Watabe, Pai, Hirota, Hosobe, Tsukada, Miura, Takano, Saito, Pauza, Hayashi, Wang, Mohinta, Mashimo, Iiizumi, Furuta, Watabe; (JOURNAL ARTICLE)

Quantum dot semiconductor nanocrystals for immunophenotyping by polychromatic flow cytometry.

Chattopadhyay, Price, Harper, Betts, Yu, Gostick, Perfetto, Goepfert, Koup, De Rosa, Bruchez, Roederer; (JOURNAL ARTICLE)

Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma.

Thaker, Han, Kamat, Arevalo, Takahashi, Lu, Jennings, Armaiz-Pena, Bankson, Ravoori, Merritt, Lin, Mangala, Kim, Coleman, Landen, Li, Felix, Sanguino, Newman, Lloyd, Gershenson, Kundra, Lopez-Berestein, Lutgendorf, Cole, Sood; (JOURNAL ARTICLE)


Nature Genetics

Has the chimpanzee Y chromosome been sequenced?

Hughes, Skaletsky, Rozen, Wilson, Page; (Journal Article)

Closing in on complex traits.

Darvasi; (Journal Article)

TranscriptSNPView: a genome-wide catalog of mouse coding variation.

Cunningham, Rios, Griffiths, Smith, Ning, Cox, Flicek, Marin-Garcin, Herrero, Rogers, van der Weyden, Bradley, Birney, Adams; (Journal Article)

Animal research and the search for understanding.

Thomas; (Journal Article)

Erratum: Identification of the gene responsible for methylmalonic aciduria and homocystinuria, cblC type.

Lerner-Ellis, Tirone, Pawelek, Doré, Atkinson, Watkins, Morel, Fujiwara, Moras, Hosack, Dunbar, Antonicka, Forgetta, Dobson, Leclerc, Gravel, Shoubridge, Coulton, Lepage, Rommens, Morgan, Rosenblatt; (Journal Article)

Context-dependent cancer risk.

Hunter; (Journal Article)

Reply to "Has the chimpanzee Y chromosome been sequenced?".

Kuroki, Taylor, Noguchi, Ito, Toyoda, Sakaki, Fujiyama; (Journal Article)

RNA interference machinery influences the nuclear organization of a chromatin insulator.

Lei, Corces; (Journal Article)

Touching base.

none; (Journal Article)

The germinating seed of Arab genomics.

none; (Journal Article)

Corrigendum: PLA2G6, encoding a phospholipase A(2), is mutated in neurodegenerative disorders with high brain iron.

Morgan, Westaway, Morton, Gregory, Gissen, Sonek, Cangul, Coryell, Canham, Nardocci, Zorzi, Pasha, Rodriguez, Desguerre, Mubaidin, Bertini, Trembath, Simonati, Schanen, Johnson, Levinson, Woods, Wilmot, Kramer, Gitschier, Maher, Hayflick; (Journal Article)

The difference between simple and complex leaves.

Kellogg; (Journal Article)

Reply to "Normalization procedures and detection of linkage signal in genetical-genomics experiments".

Chesler, Bystrykh, de Haan, Cooke, Su, Manly, Williams; (Journal Article)

Normalization procedures and detection of linkage signal in genetical-genomics experiments.

Williams, Cotsapas, Cowley, Chan, Nott, Little; (JOURNAL ARTICLE)

Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice.

Liu, Wang, Vikis, Maciag, Wang, Lu, Liu, You; (Journal Article)

Nucleic acid by-products and chronic inflammation.

Alarcón-Riquelme; (Journal Article)

Reply to "Normalization procedures and detection of linkage signal in genetical-genomics experiments".

Petretto, Mangion, Cook, Aitman, Pravenec, Schulz, Fischer, Hubner; (Journal Article)

Principal components analysis corrects for stratification in genome-wide association studies.

Price, Patterson, Plenge, Weinblatt, Shadick, Reich; (Journal Article)

From worm genetic networks to complex human diseases.

Bussey, Andrews, Boone; (Journal Article)

Research highlights.

none; (Journal Article)


Molecular Medicine


Proteomics


Nature Drug Discovery


BMC Bioinformatics

Identification of biomarkers from mass spectrometry data using a "common" peak approach.

Fushiki, Fujisawa, Eguchi; (JOURNAL ARTICLE)

New directions in biomedical text annotation: definitions, guidelines and corpus construction.

Wilbur, Rzhetsky, Shatkay; (JOURNAL ARTICLE)

Functional clustering of yeast proteins from the protein-protein interaction network.

Sen, Kloczkowski, Jernigan; (JOURNAL ARTICLE)

Cluster analysis for DNA methylation profiles having a detection threshold.

Marjoram, Chang, Laird, Siegmund; (JOURNAL ARTICLE)

Comparison and evaluation of methods for generating differentially expressed gene lists from microarray data.

Jeffery, Higgins, Culhane; (JOURNAL ARTICLE)

A literature-based similarity metric for biological processes.

Chagoyen, Carmona-Saez, Gil, Carazo, Pascual-Montano; (JOURNAL ARTICLE)

Improving the quality of protein structure models by selecting from alignment alternatives.

Sommer, Toppo, Sander, Lengauer, Tosatto; (JOURNAL ARTICLE)

A fast SCOP fold classification system using content-based E-Predict algorithm.

Chi, Shyu, Xu; (JOURNAL ARTICLE)

A direct comparison of protein interaction confidence assignment schemes.

Suthram, Shlomi, Ruppin, Sharan, Ideker; (JOURNAL ARTICLE)

Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps.

Ohlson, Aggarwal, Elofsson, Maccallum; (JOURNAL ARTICLE)

PIPE: a protein-protein interaction prediction engine based on the re-occurring short polypeptide sequences between known interacting protein pairs.

Pitre, Dehne, Chan, Cheetham, Duong, Emili, Gebbia, Greenblatt, Jessulat, Krogan, Luo, Golshani; (JOURNAL ARTICLE)


Bioinformatics

ARTS: accurate recognition of transcription starts in human.

Sonnenburg, Zien, Rätsch; (Journal Article)

A probabilistic approach to protein backbone tracing in electron density maps.

Dimaio, Shavlik, Phillips; (Journal Article)

Semi-supervised learning via penalized mixture model with application to microarray sample classification.

Pan, Shen, Jiang, Hebbel; (JOURNAL ARTICLE)

Accessing bioscience images from abstract sentences.

Yu, Lee; (Journal Article)

Mutation parameters from DNA sequence data using graph theoretic measures on lineage trees.

Magori-Cohen, Louzoun, Kleinstein; (Journal Article)

A sequence-based filtering method for ncRNA identification and its application to searching for riboswitch elements.

Zhang, Borovok, Aharonowitz, Sharan, Bafna; (Journal Article)

SNP Function Portal: a web database for exploring the function implication of SNP alleles.

Wang, Dai, Xuan, McEachin, Jackson, Scott, Athey, Watson, Meng; (Journal Article)

Learning MHC I--peptide binding.

Jojic, Reyes-Gomez, Heckerman, Kadie, Schueler-Furman; (Journal Article)

What should be expected from feature selection in small-sample settings.

Sima, Dougherty; (JOURNAL ARTICLE)

Identification of function-associated loop motifs and application to protein function prediction.

Espadaler, Querol, Aviles, Oliva; (JOURNAL ARTICLE)

Comparative footprinting of DNA-binding proteins.

Contreras-Moreira, Collado-Vides; (Journal Article)

Automatic clustering of orthologs and inparalogs shared by multiple proteomes.

Alexeyenko, Tamas, Liu, Sonnhammer; (Journal Article)

Author index.

none; (Journal Article)

Context-specific independence mixture modeling for positional weight matrices.

Georgi, Schliep; (Journal Article)

Indel seeds for homology search.

Mak, Gelfand, Benson; (Journal Article)

ZPRED: Predicting the distance to the membrane center for residues in {alpha}-helical membrane proteins.

Granseth, Viklund, Elofsson; (Journal Article)

Informative priors based on transcription factor structural class improve de novo motif discovery.

Narlikar, Gordân, Ohler, Hartemink; (Journal Article)

DynaPred: A structure and sequence based method for the prediction of MHC class I binding peptide sequences and conformations.

Antes, Siu, Lengauer; (Journal Article)

Predicting the prognosis of breast cancer by integrating clinical and microarray data with Bayesian networks.

Gevaert, Smet, Timmerman, Moreau, Moor; (Journal Article)

Improved Pruning algorithms and Divide-and-Conquer strategies for Dead-End Elimination, with application to protein design.

Georgiev, Lilien, Donald; (Journal Article)

Comparative genomics reveals unusually long motifs in mammalian genomes.

Jones, Pevzner; (Journal Article)

Identifying cycling genes by combining sequence homology and expression data.

Lu, Rosenfeld, Bar-Joseph; (Journal Article)

Create and assess protein networks through molecular characteristics of individual proteins.

Ofran, Yachdav, Mozes, Soong, Nair, Rost; (Journal Article)

ProfilePSTMM: capturing tree-structure motifs in carbohydrate sugar chains.

Aoki-Kinoshita, Ueda, Mamitsuka, Kanehisa; (Journal Article)

Rapid knot detection and application to protein structure prediction.

Khatib, Weirauch, Rohl; (Journal Article)

Identification of metabolic units induced by environmental signals.

Nacher, Schwartz, Kanehisa, Akutsu; (Journal Article)

Distance based algorithms for small biomolecule classification and structural similarity search.

Karakoc, Cherkasov, Sahinalp; (Journal Article)

MotifCut: regulatory motifs finding with maximum density subgraphs.

Fratkin, Naughton, Brutlag, Batzoglou; (Journal Article)

ISMB 2006 Organization.

none; (Journal Article)

On counting position weight matrix matches in a sequence, with application to discriminative motif finding.

Sinha; (Journal Article)

Finding novel genes in bacterial communities isolated from the environment.

Krause, Diaz, Bartels, Edwards, Pühler, Rohwer, Meyer, Stoye; (Journal Article)

Ismb 2006.

Bourne, Brunak; (Journal Article)

A decompositional approach to parameter estimation in pathway modeling: a case study of the Akt and MAPK pathways and their crosstalk.

Koh, Teong, Clément, Hsu, Thiagarajan; (Journal Article)

Interpreting anonymous DNA samples from mass disasters--probabilistic forensic inference using genetic markers.

Lin, Myers, Xing; (Journal Article)

Semi-supervised LC/MS alignment for differential proteomics.

Fischer, Grossmann, Roth, Gruissem, Baginsky, Buhmann; (Journal Article)

A model-based approach for mining membrane protein crystallization trials.

Asur, Raman, Otey, Parthasarathy; (Journal Article)

Finding motifs from all sequences with and without binding sites*

Leung, Chin; (JOURNAL ARTICLE)

arrayQCplot: software for checking the quality of microarray data.

Lee, Yi, Park; (JOURNAL ARTICLE)

ALIBABA: PubMed as a graph.

Plake, Schiemann, Pankalla, Hakenberg, Leser; (JOURNAL ARTICLE)

BNTagger: improved tagging SNP selection using Bayesian networks.

Lee, Shatkay; (Journal Article)

Semi-supervised analysis of gene expression profiles for lineage-specific development in the Caenorhabditis elegans embryo.

Qi, Missiuro, Kapoor, Hunter, Jaakkola, Gifford, Ge; (Journal Article)

Prediction of mRNA polyadenylation sites by support vector machine.

Cheng, Miura, Tian; (JOURNAL ARTICLE)

Novel unsupervised feature filtering of biological data.

Varshavsky, Gottlieb, Linial, Horn; (Journal Article)

Finding the evidence for protein-protein interactions from PubMed abstracts.

Jang, Lim, Lim, Park, Lee, Park; (Journal Article)

Quantification of transcription factor expression from Arabidopsis images.

Mace, Lee, Twigg, Colinas, Benfey, Ohler; (Journal Article)

Computational inference of the molecular logic for synaptic connectivity in C. elegans.

Varadan, Miller, Anastassiou; (Journal Article)

Protein classification using ontology classification.

Wolstencroft, Lord, Tabernero, Brass, Stevens; (Journal Article)

Integrating copy number polymorphisms into array CGH analysis using a robust HMM.

Shah, Xuan, Deleeuw, Khojasteh, Lam, Ng, Murphy; (Journal Article)

Efficient identification of DNA hybridization partners in a sequence database.

Mann, Noble; (Journal Article)

An integrative approach for causal gene identification and gene regulatory pathway inference.

Tu, Wang, Arbeitman, Chen, Sun; (Journal Article)

The iRMSD: a local measure of sequence alignment accuracy using structural information.

Armougom, Moretti, Keduas, Notredame; (Journal Article)

Simultaneous identification of differential gene expression and connectivity in inflammation, adipogenesis and cancer.

Reverter, Ingham, Lehnert, Tan, Wang, Ratnakumar, Dalrymple; (JOURNAL ARTICLE)

Analysis of sample set enrichment scores: assaying the enrichment of sets of genes for individual samples in genome-wide expression profiles.

Edelman, Porrello, Guinney, Balakumaran, Bild, Febbo, Mukherjee; (Journal Article)

An equilibrium partitioning model connecting gene expression and cis-motif content.

Mellor, Delisi; (Journal Article)

Bayesian search of functionally divergent protein subgroups and their function specific residues.

Marttinen, Corander, Törönen, Holm; (JOURNAL ARTICLE)

springScape: visualisation of microarray and contextual bioinformatic data using spring embedding and an 'information landscape'.

Ebbels, Buxton, Jones; (Journal Article)

ARCS: an aggregated related column scoring scheme for aligned sequences.

Song, Choi, Chen, Szymanski, Zhang, Tung, Kang, Kim, Yang; (JOURNAL ARTICLE)

JVirGel 2.0: computational prediction of proteomes separated via two dimensional gel electrophoresis under consideration of membrane and secreted proteins.

Hiller, Grote, Maneck, Münch, Jahn; (JOURNAL ARTICLE)

Dense subgraph computation via stochastic search: application to detect transcriptional modules.

Everett, Wang, Hannenhalli; (Journal Article)

CONTRAfold: RNA secondary structure prediction without physics-based models.

Do, Woods, Batzoglou; (Journal Article)

Apples to apples: improving the performance of motif finders and their significance analysis in the Twilight Zone.

Ng, Nagarajan, Jones, Keich; (Journal Article)

BaCelLo: a balanced subcellular localization predictor.

Pierleoni, Martelli, Fariselli, Casadio; (Journal Article)

Inferring functional pathways from multi-perturbation data.

Yosef, Kaufman, Ruppin; (Journal Article)

Annotating proteins by mining protein interaction networks.

Kirac, Ozsoyoglu, Yang; (Journal Article)

An experimental metagenome data management and analysis system.

Markowitz, Ivanova, Palaniappan, Szeto, Korzeniewski, Lykidis, Anderson, Mavrommatis, Kunin, Garcia Martin, Dubchak, Hugenholtz, Kyrpides; (Journal Article)

Inferring gene regulatory networks from multiple microarray datasets.

Wang, Joshi, Zhang, Xu, Chen; (JOURNAL ARTICLE)

A combinatorial pattern discovery approach for the prediction of membrane dipping (re-entrant) loops.

Lasso, Antoniw, Mullins; (Journal Article)

Peptide sequence tag-based blind identification of post-translational modifications with point process model.

Liu, Yan, Song, Xu, Cai; (Journal Article)

AClAP, Autonomous hierarchical agglomerative Cluster Analysis based protocol to partition conformational datasets.

Bottegoni, Rocchia, Recanatini, Cavalli; (Journal Article)

Hairpins in a Haystack: recognizing microRNA precursors in comparative genomics data.

Hertel, Stadler; (Journal Article)

Integrating image data into biomedical text categorization.

Shatkay, Chen, Blostein; (Journal Article)

Modelling sequential protein folding under kinetic control.

Huard, Deane, Wood; (Journal Article)

To permute or not to permute.

Huang, Xu, Calian, Hsu; (JOURNAL ARTICLE)

Statistical mechanical modeling of genome-wide transcription factor occupancy data by MatrixREDUCE.

Foat, Morozov, Bussemaker; (Journal Article)

An ontology for a Robot Scientist.

Soldatova, Clare, Sparkes, King; (Journal Article)

A computational approach toward label-free protein quantification using predicted peptide detectability.

Tang, Arnold, Alves, Xun, Clemmer, Novotny, Reilly, Radivojac; (Journal Article)

Constructing Near-Perfect Phylogenies with multiple homoplasy events.

Satya, Mukherjee, Alexe, Parida, Bhanot; (Journal Article)

Decoding non-unique oligonucleotide hybridization experiments of targets related by a phylogenetic tree.

Schliep, Rahmann; (Journal Article)

Integrating structured biological data by Kernel Maximum Mean Discrepancy.

Borgwardt, Gretton, Rasch, Kriegel, Schölkopf, Smola; (Journal Article)

Bistable switching and excitable behaviour in the activation of Src at mitosis.

Fuss, Dubitzky, Downes, Kurth; (Journal Article)

Relative contributions of structural designability and functional diversity in molecular evolution of duplicates.

Shakhnovich; (Journal Article)

Bio-ontology and text: bridging the modeling gap.

Friedman, Borlawsky, Shagina, Xing, Lussier; (JOURNAL ARTICLE)

A novel structure-based encoding for machine-learning applied to the inference of SH3 domain specificity.

Ferraro, Via, Ausiello, Helmer-Citterich; (JOURNAL ARTICLE)

Dynamical analysis of a generic Boolean model for the control of the mammalian cell cycle.

Fauré, Naldi, Chaouiya, Thieffry; (Journal Article)

A top-level ontology of functions and its application in the Open Biomedical Ontologies.

Burek, Hoehndorf, Loebe, Visagie, Herre, Kelso; (Journal Article)


Proc Natl Acad Sci U S A

Genome analysis of the smallest free-living eukaryote Ostreococcus tauri unveils many unique features.

Derelle, Ferraz, Rombauts, Rouzé, Worden, Robbens, Partensky, Degroeve, Echeynié, Cooke, Saeys, Wuyts, Jabbari, Bowler, Panaud, Piégu, Ball, Ral, Bouget, Piganeau, De Baets, Picard, Delseny, Demaille, Van de Peer, Moreau; (JOURNAL ARTICLE)

Functional development of Src tyrosine kinases during evolution from a unicellular ancestor to multicellular animals.

Segawa, Suga, Iwabe, Oneyama, Akagi, Miyata, Okada; (JOURNAL ARTICLE)

Targeting lentiviral vectors to specific cell types in vivo.

Yang, Bailey, Baltimore, Wang; (JOURNAL ARTICLE)

Identification and characterization of a lysophosphatidylcholine acyltransferase in alveolar type II cells.

Chen, Hyatt, Mucenski, Mason, Shannon; (JOURNAL ARTICLE)

Characterization of mycobacterial virulence genes through genetic interaction mapping.

Joshi, Pandey, Capite, Fortune, Rubin, Sassetti; (JOURNAL ARTICLE)

Repression and loss of gene expression outpaces activation and gain in recently duplicated fly genes.

Oakley, Ostman, Wilson; (JOURNAL ARTICLE)

Nanodiscs separate chemoreceptor oligomeric states and reveal their signaling properties.

Boldog, Grimme, Li, Sligar, Hazelbauer; (JOURNAL ARTICLE)

Direct observation of DNA rotation during branch migration of Holliday junction DNA by Escherichia coli RuvA-RuvB protein complex.

Han, Tani, Hayashi, Hishida, Iwasaki, Shinagawa, Harada; (JOURNAL ARTICLE)

Robust, bistable patterning of the dorsal surface of the Drosophila embryo.

Umulis, Serpe, O'connor, Othmer; (JOURNAL ARTICLE)

DRB1*0401-restricted human T cell clone specific for the major proinsulin73-90 epitope expresses a down-regulatory T helper 2 phenotype.

Durinovic-Belló, Rosinger, Olson, Congia, Ahmad, Rickert, Hampl, Kalbacher, Drijfhout, Mellins, Al Dahouk, Kamradt, Maeurer, Nhan, Roep, Boehm, Polychronakos, Nepom, Karges, McDevitt, Sønderstrup; (JOURNAL ARTICLE)

Quantitative high-throughput screening: A titration-based approach that efficiently identifies biological activities in large chemical libraries.

Inglese, Auld, Jadhav, Johnson, Simeonov, Yasgar, Zheng, Austin; (JOURNAL ARTICLE)

An early role for Sonic hedgehog from foregut endoderm in jaw development: Ensuring neural crest cell survival.

Brito, Teillet, Le Douarin; (JOURNAL ARTICLE)

Noninvasive imaging of islet grafts using positron-emission tomography.

Lu, Dang, Middleton, Zhang, Washburn, Stout, Campbell-Thompson, Atkinson, Phelps, Gambhir, Tian, Kaufman; (Journal Article)

Bacterial stalks are nutrient-scavenging antennas.

McAdams; (JOURNAL ARTICLE)

Aptamers evolved from live cells as effective molecular probes for cancer study.

Shangguan, Li, Tang, Cao, Chen, Mallikaratchy, Sefah, Yang, Tan; (JOURNAL ARTICLE)

The regulatory utilization of genetic redundancy through responsive backup circuits.

Kafri, Levy, Pilpel; (JOURNAL ARTICLE)

Liprin-{alpha} has LAR-independent functions in R7 photoreceptor axon targeting.

Hofmeyer, Maurel-Zaffran, Sink, Treisman; (JOURNAL ARTICLE)

Scaling and saturation laws for the expansion of concrete exposed to sulfate attack.

Monteiro; (JOURNAL ARTICLE)

Tension-dependent DNA cleavage by restriction endonucleases: Two-site enzymes are "switched off" at low force.

Gemmen, Millin, Smith; (JOURNAL ARTICLE)

Vascularized organoid engineered by modular assembly enables blood perfusion.

McGuigan, Sefton; (JOURNAL ARTICLE)

The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis.

Hayakawa, Leonard, Murphy, Hayes, Soto, Fogarty, Standley, Bellve, Lambright, Mello, Corvera; (JOURNAL ARTICLE)

Involvement of Rad18 in somatic hypermutation.

Bachl, Ertongur, Jungnickel; (JOURNAL ARTICLE)

E2-25K mediates US11-triggered retro-translocation of MHC class I heavy chains in a permeabilized cell system.

Flierman, Coleman, Pickart, Rapoport, Chau; (JOURNAL ARTICLE)

Role of the Arabidopsis DNA glycosylase/lyase ROS1 in active DNA demethylation.

Agius, Kapoor, Zhu; (JOURNAL ARTICLE)

Transcriptional inactivation of a regulatory site for replication of Vibrio cholerae chromosome II.

Venkova-Canova, Srivastava, Chattoraj; (JOURNAL ARTICLE)

The cotton fiber zinc-binding domain of cellulose synthase A1 from Gossypium hirsutum displays rapid turnover in vitro and in vivo.

Jacob-Wilk, Kurek, Hogan, Delmer; (JOURNAL ARTICLE)

Profile of Lonnie G. Thompson.

Zagorski; (JOURNAL ARTICLE)

Cellular asymmetry and individuality in directional sensing.

Samadani, Mettetal, van Oudenaarden; (JOURNAL ARTICLE)

Macromolecular-scale resolution in biological fluorescence microscopy.

Donnert, Keller, Medda, Andrei, Rizzoli, Lührmann, Jahn, Eggeling, Hell; (JOURNAL ARTICLE)

Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli.

Wu, McCandlish, Gronenberg, Chng, Silhavy, Kahne; (JOURNAL ARTICLE)

Different mitochondrial intermembrane space proteins are released during apoptosis in a manner that is coordinately initiated but can vary in duration.

Muñoz-Pinedo, Guío-Carrión, Goldstein, Fitzgerald, Newmeyer, Green; (JOURNAL ARTICLE)

Free-energy distribution of binary protein-protein binding suggests cross-species interactome differences.

Shi, Miller, Qian, Bomsztyk; (JOURNAL ARTICLE)

Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury.

Ikeda-Matsuo, Ota, Fukada, Uematsu, Akira, Sasaki; (JOURNAL ARTICLE)

B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia.

Yan, Albesiano, Zanesi, Yancopoulos, Sawyer, Romano, Petlickovski, Efremov, Croce, Chiorazzi; (JOURNAL ARTICLE)

Ecological and immunological determinants of dengue epidemics.

Wearing, Rohani; (JOURNAL ARTICLE)

A family of conserved noncoding elements derived from an ancient transposable element.

Xie, Kamal, Lander; (JOURNAL ARTICLE)

Modulation of competing memory systems by distraction.

Foerde, Knowlton, Poldrack; (JOURNAL ARTICLE)

Enhancing molecular flux through nanopores by means of attractive interactions.

Kasianowicz, Nguyen, Stanford; (JOURNAL ARTICLE)

Beyond the metal-insulator transition in polymer electrolyte gated polymer field-effect transistors.

Dhoot, Yuen, Heeney, McCulloch, Moses, Heeger; (JOURNAL ARTICLE)

Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial function.

Wang, Li, Lu, Du, Katiyar, Yang, Fu, Leader, Quong, Novikoff, Pestell; (JOURNAL ARTICLE)

A mechanism to signal receptor-substrate interactions with luminescent quantum dots.

Yildiz, Tomasulo, Raymo; (JOURNAL ARTICLE)

MPS1-dependent mitotic BLM phosphorylation is important for chromosome stability.

Leng, Chan, Luo, Zhu, Qin, Wang; (JOURNAL ARTICLE)

Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption.

Kinoshita, McDannold, Jolesz, Hynynen; (JOURNAL ARTICLE)

The Ets factor Spi-B is a direct critical target of the coactivator OBF-1.

Bartholdy, Du Roure, Bordon, Emslie, Corcoran, Matthias; (JOURNAL ARTICLE)

Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1.

Butovsky, Koronyo-Hamaoui, Kunis, Ophir, Landa, Cohen, Schwartz; (JOURNAL ARTICLE)

CDC7 kinase phosphorylates serine residues adjacent to acidic amino acids in the minichromosome maintenance 2 protein.

Cho, Lee, Kong, Hurwitz, Lee; (JOURNAL ARTICLE)

Genome complexity in a lean, mean photosynthetic machine.

Archibald; (JOURNAL ARTICLE)

Adaptive response of Yersinia pestis to extracellular effectors of innate immunity during bubonic plague.

Sebbane, Lemaître, Sturdevant, Rebeil, Virtaneva, Porcella, Hinnebusch; (JOURNAL ARTICLE)

Reversal of RNA missplicing and myotonia after muscleblind overexpression in a mouse poly(CUG) model for myotonic dystrophy.

Kanadia, Shin, Yuan, Beattie, Wheeler, Thornton, Swanson; (JOURNAL ARTICLE)

Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy.

Kannankeril, Mitchell, Goonasekera, Chelu, Zhang, Sood, Kearney, Danila, De Biasi, Wehrens, Pautler, Roden, Taffet, Dirksen, Anderson, Hamilton; (JOURNAL ARTICLE)

Checkpoint kinase 1 (Chk1) is required for mitotic progression through negative regulation of polo-like kinase 1 (Plk1).

Tang, Erikson, Liu; (JOURNAL ARTICLE)

Sympatric speciation under incompatibility selection.

Artzy-Randrup, Kondrashov; (JOURNAL ARTICLE)

N-Myc and the cyclin-dependent kinase inhibitors p18Ink4c and p27Kip1 coordinately regulate cerebellar development.

Zindy, Knoepfler, Xie, Sherr, Eisenman, Roussel; (JOURNAL ARTICLE)

Molecular dynamics analyses of cross-{beta}-spine steric zipper models: {beta}-Sheet twisting and aggregation.

Esposito, Pedone, Vitagliano; (JOURNAL ARTICLE)

The role of the proline-rich domain of Ssdp1 in the modular architecture of the vertebrate head organizer.

Enkhmandakh, Makeyev, Bayarsaihan; (JOURNAL ARTICLE)

Carcinogens induce genome-wide loss of heterozygosity in normal stem cells without persistent chromosomal instability.

Donahue, Lin, Cao, Ruley; (JOURNAL ARTICLE)

Solution structure of Urm1 and its implications for the origin of protein modifiers.

Xu, Zhang, Wang, Zhou, Huang, Wu, Zhong, Shi; (JOURNAL ARTICLE)

Differential HIV-1 replication in neonatal and adult blood mononuclear cells is influenced at the level of HIV-1 gene expression.

Sundaravaradan, Saxena, Ramakrishnan, Yedavalli, Harris, Ahmad; (JOURNAL ARTICLE)

Molecular transport through channels and pores: Effects of in-channel interactions and blocking.

Bauer, Nadler; (JOURNAL ARTICLE)

Spatial remapping of touch: Confusion of perceived stimulus order across hand and foot.

Schicke, Röder; (JOURNAL ARTICLE)

Regulation of T cell activation and tolerance by PDL2.

Zhang, Chung, Bishop, Daugherty, Chute, Holst, Kurahara, Lott, Sun, Welcher, Dong; (JOURNAL ARTICLE)

Structural basis for unique mechanisms of folding and hemoglobin binding by a malarial protease.

Wang, Pandey, Somoza, Sijwali, Kortemme, Brinen, Fletterick, Rosenthal, McKerrow; (JOURNAL ARTICLE)

Unique risk factors for insertional mutagenesis in a mouse model of XSCID gene therapy.

Shou, Ma, Lu, Sorrentino; (JOURNAL ARTICLE)

Quantitative NMR analysis of the protein G B1 domain in Xenopus laevis egg extracts and intact oocytes.

Selenko, Serber, Gadea, Ruderman, Wagner; (JOURNAL ARTICLE)

Structural basis for the design of potent and species-specific inhibitors of 3-hydroxy-3-methylglutaryl CoA synthases.

Pojer, Ferrer, Richard, Nagegowda, Chye, Bach, Noel; (JOURNAL ARTICLE)

Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate.

Bornstein, Ganoth, Hershko; (JOURNAL ARTICLE)

Liprin-{alpha} is required for photoreceptor target selection in Drosophila.

Choe, Prakash, Bright, Clandinin; (JOURNAL ARTICLE)

A nutrient uptake role for bacterial cell envelope extensions.

Wagner, Setayeshgar, Sharon, Reilly, Brun; (JOURNAL ARTICLE)


N Engl J Med

Clopidogrel for the prevention of atherothrombotic events.

Rabinstein; (Comment, Letter)

The silent epidemic--the health effects of illiteracy.

Marcus; (Journal Article)

Counseling plus buprenorphine-naloxone maintenance therapy for opioid dependence.

Fiellin, Pantalon, Chawarski, Moore, Sullivan, O'Connor, Schottenfeld; (Journal Article)

Clopidogrel for the prevention of atherothrombotic events.

Almanaseer, Desai; (Comment, Letter)

Case records of the Massachusetts General Hospital. Case 23-2006. A 36-year-old man with numbness in the right hand and hypertension.

Iliopoulos, Chan-Smutko, Gonzalez, Louis, Stone; (Clinical Conference, Journal Article)

Clopidogrel for the prevention of atherothrombotic events.

Rozenman; (Comment, Letter)

Patient-specific embryonic stem cells derived from human SCNT blastocysts.

none; (Retraction of Publication)

Pay-for-performance programs in family practices in the United Kingdom.

Doran, Fullwood, Gravelle, Reeves, Kontopantelis, Hiroeh, Roland; (Journal Article)

Medical mystery: arthritis--the answer.

Jansen, Spoorenberg; (Letter)

Clinical practice. Resistant or difficult-to-control hypertension.

Moser, Setaro; (Journal Article)

Clopidogrel for the prevention of atherothrombotic events.

Kamalesh; (Comment, Letter)

The price of growth in the medical-device industry.

Garber; (Journal Article)

Treating prehypertension.

Baumann, van den Born; (Comment, Letter)

Treating prehypertension.

Grassi; (Comment, Letter)

Inhaled NO for preterm infants--getting to yes?

Stark; (Comment, Editorial)

Inhaled nitric oxide in preterm infants undergoing mechanical ventilation.

Ballard, Truog, Cnaan, Martin, Ballard, Merrill, Walsh, Durand, Mayock, Eichenwald, Null, Hudak, Puri, Golombek, Courtney, Stewart, Welty, Phibbs, Hibbs, Luan, Wadlinger, Asselin, Coburn; (Journal Article)

Paying for performance in the United States and abroad.

Epstein; (Comment, Editorial)

Twin girls with neurocutaneous symptoms caused by mothball intoxication.

Feuillet, Mallet, Spadari; (Letter)

Images in clinical medicine. A medical mystery: abnormal chest X-ray film.

Turkington, McAteer; (Journal Article)

Treating prehypertension.

Lopez-Plasencia, Amela-Peris, Garcia-Delgado; (Comment, Letter)

Case 13-2006: a man with a bone mass and lesions in the liver.

Schwartz; (Comment, Letter)

Early inhaled nitric oxide therapy in premature newborns with respiratory failure.

Kinsella, Cutter, Walsh, Gerstmann, Bose, Hart, Sekar, Auten, Bhutani, Gerdes, George, Southgate, Carriedo, Couser, Mammel, Hall, Pappagallo, Sardesai, Strain, Baier, Abman; (Journal Article)

Treating prehypertension.

Conen, Martina; (Comment, Letter)

The troubled transformation of Britain's National Health Service.

Klein; (Journal Article)

Clopidogrel for the prevention of atherothrombotic events.

Kongsaengdao, Arayawichanont; (Comment, Letter)


J Natl Cancer Inst


Lancet

Making the UK's National Health Service cost effective.

Smith; (Comment, Letter)

Communicating science.

none; (Editorial)

Revenge of the hymenoptera.

Taylor; (Journal Article)

Designer drug Subutex takes its toll in Tbilisi.

Parfitt; (News)

Brian Oliver Lyndhurst Duke.

Pincock; (Biography, Historical Article, Journal Article)

Focus on childhood fitness, not just fatness.

Weiss, Raz; (Comment, Journal Article)

Rotavirus vaccines: current prospects and future challenges.

Glass, Parashar, Bresee, Turcios, Fischer, Widdowson, Jiang, Gentsch; (Journal Article, Review)

Physical activity and clustered cardiovascular risk in children: a cross-sectional study (The European Youth Heart Study).

Andersen, Harro, Sardinha, Froberg, Ekelund, Brage, Anderssen; (Journal Article, Multicenter Study)

Blood tests for diagnosis of tuberculosis.

Phadke, Kshirsagar; (Comment, Letter)

Canadian Aboriginal people's health and the Kelowna deal.

Webster; (News)

Virological and immunological outcomes at 3 years after starting antiretroviral therapy with regimens containing non-nucleoside reverse transcriptase inhibitor, protease inhibitor, or both in INITIO: open-label randomised trial.

Yeni, Cooper, Aboulker, Babiker, Carey, Darbyshire, Floridia, Girard, Goodall, Hooker, Mijch, Meiffredy, Salzberger; (Journal Article, Multicenter Study, Randomized Controlled Trial)

Shared decision making in deceased-donor transplantation.

Ross, Zenios, Thistlethwaite; (Journal Article)

Soil-transmitted helminth infections.

Bailey; (Comment, Letter)

Is the need for ART being grossly underestimated?

England; (Comment, Letter)

Don't forget pharmacognosy.

none; (Editorial)

Vladimir Mendelevich: fighting for drug substitution treatment.

Parfitt; (Biography, Historical Article, Journal Article)

Chinese herbal uropathy and nephropathy.

Laing, Hamour, Sheaff, Miller, Woolfson; (Case Reports, Journal Article)

Soil-transmitted helminth infections.

Meltzer; (Comment, Letter)

Tobacco industry research on smoking and cigarette toxicity.

Hammond; (Comment, Letter)

Knowing me, knowing ewe.

Watts; (Journal Article)

The decline of academic medicine.

Druml, Singer, Wolzt; (Comment, Letter)

Making health a G8 priority.

none; (Editorial)

Funding for practice-oriented clinical research.

Rothwell; (Journal Article)

The decline of academic medicine.

Matthys; (Comment, Letter)

FDA regulation of tobacco: reprieve for the Marlboro man?

Siegel, Blum; (Journal Article)

Disaster-related mental health: indoctrination or collaboration?

Van Eenwyk, Jayawickrama; (Comment, Letter)

The decline of academic medicine.

Yusuf; (Comment, Letter)

Bronchiolitis.

Smyth, Openshaw; (Journal Article, Review)

Government tobacco regulation: opportunity for change.

Myers; (Comment, Journal Article)

Blood tests for diagnosis of tuberculosis.

Kampmann, Tena-Coki, Anderson; (Comment, Letter)

Is access to essential medicines as part of the fulfilment of the right to health enforceable through the courts?

Hogerzeil, Samson, Casanovas, Rahmani-Ocora; (Journal Article)


Expert Rev Mol Diagn