Nature

The inner-nuclear-envelope protein emerin regulates HIV-1 infectivity.

Jacque, Stevenson; (JOURNAL ARTICLE)

Special provision.

none; (Editorial)

Allergy test might have avoided drug-trial disaster.

Weis; (Comment, Letter)

Identification of a tumour suppressor network opposing nuclear Akt function.

Trotman, Alimonti, Scaglioni, Koutcher, Cordon-Cardo, Pandolfi; (JOURNAL ARTICLE)

Geochemistry: the noble art of recycling.

Matsumoto; (Comment, News)

Making the paper: Alan Aderem.

none; (Journal Article)

In brief.

none; (Journal Article)

Seeing the big picture.

Hoag; (Journal Article)

A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting.

Namy, Moran, Stuart, Gilbert, Brierley; (Journal Article)

Abstractions.

none; (Journal Article)

Thermodynamics: when a phase is born.

Debenedetti; (News)

Quantified: australia.

none; (Journal Article)

Vaccines: engineering immune evasion.

Mascola; (Comment, News)

Corrigendum: Lipid-protein interactions in double-layered two-dimensional AQP0 crystals.

Gonen, Cheng, Sliz, Hiroaki, Fujiyoshi, Harrison, Walz; (Journal Article)

50 & 100 years ago.

none; (Journal Article)

Renaissance magic and mysticism.

Knoeff; (Journal Article)

Analytical chemistry: cause for a llama.

Webb; (News)

Medical council funds both clinical and basic research.

Blakemore; (Comment, Letter)

Coming in from the cold.

none; (Editorial)

Local switching of two-dimensional superconductivity using the ferroelectric field effect.

Takahashi, Gabay, Jaccard, Shibuya, Ohnishi, Lippmaa, Triscone; (Journal Article)

IL-23 promotes tumour incidence and growth.

Langowski, Zhang, Wu, Mattson, Chen, Smith, Basham, McClanahan, Kastelein, Oft; (JOURNAL ARTICLE)

Are rich nations up for drug reform?

Check; (News)

Human frailties.

Tattersall; (Journal Article)

State's flu response raises concern.

Ruttimann; (News)

Keeping an eye on privacy issues with geospatial data.

Curtis, Mills, Leitner; (Comment, Letter)

Immunology: what does it mean to be just 17?

Tato, O'Shea; (Comment, News)

Diving insects boost their buoyancy bubbles.

Matthews, Seymour; (Journal Article)

Corrigendum: Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee.

Hughes, Skaletsky, Pyntikova, Minx, Graves, Rozen, Wilson, Page; (Journal Article)

Strained silicon as a new electro-optic material.

Jacobsen, Andersen, Borel, Fage-Pedersen, Frandsen, Hansen, Kristensen, Lavrinenko, Moulin, Ou, Peucheret, Zsigri, Bjarklev; (Journal Article)

Research highlights.

none; (Journal Article)

Seawater subduction controls the heavy noble gas composition of the mantle.

Holland, Ballentine; (Journal Article)

Specification of the neural crest occurs during gastrulation and requires Pax7.

Basch, Bronner-Fraser, García-Castro; (Journal Article)

A putative flip-flop switch for control of REM sleep.

Lu, Sherman, Devor, Saper; (JOURNAL ARTICLE)

Outspoken: Mike Griffin on the NASA budget.

Reichhardt; (News)

New carbon dates link climatic change with human colonization and Pleistocene extinctions.

Guthrie; (Journal Article)

Discovery of a 25-cm asteroid clast in the giant Morokweng impact crater, South Africa.

Maier, Andreoli, McDonald, Higgins, Boyce, Shukolyukov, Lugmair, Ashwal, Gräser, Ripley, Hart; (Journal Article)

Avian flu and the New World.

none; (News)

A cross-cultural relationship.

Goldstein; (Journal Article)

Arab state pours oil profits into science.

Giles; (News)

Finding your north.

Moore; (Journal Article)

Long gamma-ray bursts and core-collapse supernovae have different environments.

Fruchter, Levan, Strolger, Vreeswijk, Thorsett, Bersier, Burud, Castro Cerón, Castro-Tirado, Conselice, Dahlen, Ferguson, Fynbo, Garnavich, Gibbons, Gorosabel, Gull, Hjorth, Holland, Kouveliotou, Levay, Livio, Metzger, Nugent, Petro, Pian, Rhoads, Riess, Sahu, Smette, Tanvir, Wijers, Woosley; (JOURNAL ARTICLE)

Evolution of the selfish gene.

Sperber; (Journal Article)

Cell biology: cracking the calcium entry code.

Parekh; (Comment, News)

A journey to remember.

Dudai; (Journal Article)

The aching of Dion Harper.

Chrenkoff; (Journal Article)

Epigenetics: unfinished symphony.

Qiu; (News)

News in brief.

none; (Journal Article)

Arctic ecology: on thin ice.

Schiermeier; (News)

Chemistry: a catalytic knight's move.

Crabtree; (News)

Challengers in the field.

Macilwain; (Journal Article)

Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.

Gilchrist, Thorsson, Li, Rust, Korb, Kennedy, Hai, Bolouri, Aderem; (Journal Article)

The soldier's tale.

Ridley; (Journal Article)

Future fitness and helping in social queues.

Field, Cronin, Bridge; (Journal Article)

Corrigendum: Sporting contests: Seeing red? Putting sportswear into context.

none; (Journal Article)

Solar system: interplanetary kidnap.

Morbidelli; (Comment, News)

Let the data flow.

none; (Editorial)

Sidelines.

none; (Journal Article)

The ant trail.

Keller; (Journal Article)

Corrections.

none; (Journal Article)

A trehalose metabolic enzyme controls inflorescence architecture in maize.

Satoh-Nagasawa, Nagasawa, Malcomber, Sakai, Jackson; (Journal Article)

Science's secret service.

Greenberg; (Journal Article)

Thank you, Professor MacDonald.

McMahon, Attaya, Denison, Hockert, Shankarling; (Journal Article)

Exaggerating one's success is rife in Chinese academia.

Huang; (Journal Article)

Arctic stations need human touch.

Schiermeier; (News)

Corrigendum: An acidic protein aligns magnetosomes along a filamentous structure in magnetotactic bacteria.

Scheffel, Gruska, Faivre, Linaroudis, Graumann, Plitzko, Schüler; (Journal Article)

Neptune's capture of its moon Triton in a binary-planet gravitational encounter.

Agnor, Hamilton; (Journal Article)


Science

Plant science. Auxin transport, but in which direction?

Sieberer, Leyser; (Comment, Journal Article)

AXR4 Is Required for Localization of the Auxin Influx Facilitator AUX1.

Dharmasiri, Swarup, Mockaitis, Dharmasiri, Singh, Kowalchyk, Marchant, Mills, Sandberg, Bennett, Estelle; (JOURNAL ARTICLE)

Neuroscience. Regulating energy balance: the substrate strikes back.

Flier; (Comment, Journal Article)

Ecology. Photosymbiosis and the evolution of modern coral reefs.

Stanley; (Journal Article)

Debating sexual selection and mating strategies.

Buss; (Comment, Letter)

Debating sexual selection and mating strategies.

Day, Houle, Rowe; (Comment, Letter)

Global health. Polio eradication: is it time to give up?

Roberts; (Comment, News)

Hypothalamic mTOR signaling regulates food intake.

Cota, Proulx, Smith, Kozma, Thomas, Woods, Seeley; (Journal Article)

Condensed matter physics. Solid hydrogen not so super after all.

Cho; (News)

RISING STARS.

none; (JOURNAL ARTICLE)

Migratory birds and avian flu.

Fergus, Fry, Karesh, Marra, Newman, Paul; (Comment, Letter)

Cognitive Neuroscience Society meeting. Probing the social brain.

Miller; (News)

Formation and subdivision of deformation structures during plastic deformation.

Jakobsen, Poulsen, Lienert, Almer, Shastri, Sørensen, Gundlach, Pantleon; (Journal Article)

Increase in foreign grad students.

Yeh; (Comment, Letter)

NASA budget. Crisis deepens as scientists fail to rejigger space research.

Lawler; (News)

MOVERS.

none; (JOURNAL ARTICLE)

Statistical independence of escalatory ecological trends in Phanerozoic marine invertebrates.

Madin, Alroy, Aberhan, Fürsich, Kiessling, Kosnik, Wagner; (Journal Article)

Oceanographic basis of the global surface distribution of Prochlorococcus ecotypes.

Bouman, Ulloa, Scanlan, Zwirglmaier, Li, Platt, Stuart, Barlow, Leth, Clementson, Lutz, Fukasawa, Watanabe, Sathyendranath; (Journal Article)

FACT AND FICTION.

none; (JOURNAL ARTICLE)

Finding Criminals Through DNA of Their Relatives.

Bieber, Brenner, Lazer; (JOURNAL ARTICLE)

Nanoassembly of a Fractal Polymer: A Molecular Sierpinski "Hexagonal Gasket"

Newkome, Wang, Moorefield, Cho, Mohapatra, Li, Hwang, Lukoyanova, Echegoyen, Palagallo, Iancu, Hla; (JOURNAL ARTICLE)

Canada. Research budgets are tight pending science policy review.

Kondro; (News)

A New Genus of African Monkey, Rungwecebus: Morphology, Ecology, and Molecular Phylogenetics.

Davenport, Stanley, Sargis, De Luca, Mpunga, Machaga, Olson; (JOURNAL ARTICLE)

More silliness on the Hill.

Kennedy; (Editorial)

Scientific publishing. A cure for the common trial.

Grimm; (News)

Public health. Who should get influenza vaccine when not all can?

Emanuel, Wertheimer; (Journal Article)

Viruses: making friends with old foes.

Douglas, Young; (Journal Article)

Aggresomes and autophagy generate sites for virus replication.

Wileman; (Journal Article)

Intellectual property. Decision on NFkappaB patent could have broad implications for biotech.

Garber; (News)

Debating sexual selection and mating strategies.

Stewart; (Comment, Letter)

Fall in Earth's magnetic field is erratic.

Gubbins, Jones, Finlay; (Journal Article)

AWARDS.

none; (JOURNAL ARTICLE)

U.S. science policy. Senate panel chair asks why NSF funds social sciences.

Mervis; (News)

Global change. No doubt about it, the world is warming.

Kerr; (News)

Molecular sorting by electrical steering of microtubules in kinesin-coated channels.

van den Heuvel, de Graaff, Dekker; (Journal Article)

Multiple outbreaks and flu containment plans.

Lipsitch, Robins, Mills, Bergstrom; (Comment, Letter)

Public health. Is polio eradication realistic?

Arita, Nakane, Fenner; (Journal Article)

Type 1 interferons and the virus-host relationship: a lesson in détente .

García-Sastre, Biron; (Journal Article)

Comment on "Evidence for positive epistasis in HIV-1".

Wang, Mittler, Samudrala; (Comment, Journal Article)

Debating sexual selection and mating strategies.

Miller; (Comment, Letter)

AWARDS.

none; (JOURNAL ARTICLE)

Debating sexual selection and mating strategies.

Pizzari, Birkhead, Blows, Brooks, Buchanan, Clutton-Brock, Harvey, Hosken, Jennions, Kokko, Kotiaho, Lessells, Macias-Garcia, Moore, Parker, Partigridge, Pitnick, Radwan, Ritchie, Sheldon, Simmons, Snook, Stockley, Zuk; (Comment, Letter)

Debating sexual selection and mating strategies.

Shuker, Tregenza; (Comment, Letter)

AWARDS.

none; (JOURNAL ARTICLE)

Debating sexual selection and mating strategies.

Lessells, Bennett, Birkhead, Colegrave, Dall, Harvey, Hatchwell, Hosken, Hunt, Moore, Parker, Pitnick, Pizzari, Radwan, Ritchie, Sheldon, Shuker, Simmons, Stockley, Tregenza, Zuk; (Comment, Letter)

Impaired control of IRES-mediated translation in X-linked dyskeratosis congenita.

Yoon, Peng, Brandenburg, Zollo, Xu, Rego, Ruggero; (Journal Article)

RNA recognition and cleavage by a splicing endonuclease.

Xue, Calvin, Li; (Journal Article)

Scholarly publishing. Bill would require free public access to research papers.

Kaiser; (News)

Species diversity and ecosystem functioning.

Bunker, Naeem; (Comment, Letter)

Simultaneous negative phase and group velocity of light in a metamaterial.

Dolling, Enkrich, Wegener, Soukoulis, Linden; (Journal Article)

Observation of backward pulse propagation through a medium with a negative group velocity.

Gehring, Schweinsberg, Barsi, Kostinski, Boyd; (Journal Article)

Debating sexual selection and mating strategies.

Hurd; (Comment, Letter)

Paradigms in the Virosphere.

Ash, Hurtley, Lavine, Simpson; (JOURNAL ARTICLE)

Astronomy. A Hawaiian upstart prepares to monitor the starry heavens.

Irion; (News)

Debating sexual selection and mating strategies.

Ghiselin; (Comment, Letter)

Geophysics. Ships' logs and archeomagnetism.

Kono; (Comment, Journal Article)

The Pathway of Carbon in Nature.

Hayes; (JOURNAL ARTICLE)

Public health. Progress toward rotavirus vaccines.

Parashar, Glass; (Journal Article)

Materials science. Collective defect behavior under stress.

Kubin; (Comment, Journal Article)

Scientific publishing. A call to improve South Africa's journals.

Koenig; (News)

Materials science. Toward devices powered by biomolecular motors.

Hess; (Comment, Journal Article)

Ischemia opens neuronal gap junction hemichannels.

Thompson, Zhou, MacVicar; (Journal Article)

Did DNA come from viruses?

Zimmer; (News)

Biomarker Evidence for a Major Preservation Pathway of Sedimentary Organic Carbon.

Hebting, Schaeffer, Behrens, Adam, Schmitt, Schneckenburger, Bernasconi, Albrecht; (JOURNAL ARTICLE)


Nature Methods

SAILing toward larger protein structures.

Doerr; (Journal Article)

Chemical nano-corking.

Doerr; (Journal Article)

Tracking the wily transcription factor.

Eisenstein; (Journal Article)

Small molecules as geneticists.

Evanko; (Journal Article)

A new twist for DNA.

Eisenstein; (Journal Article)

Janus face of DNA.

Rusk; (Journal Article)

Mimicking nature with protein scaffolds.

Evanko; (Journal Article)

My enemy's enemy is my friend.

Eisenstein; (Journal Article)


Nature Biotechnology

Profile: alexis borisy.

Schmidt; (Journal Article)

Gold in the ivory tower: equity rewards of outlicensing.

Edwards, Murray, Yu; (Journal Article)

New pharma-biotech company formation in India.

Saberwal; (Journal Article)

People.

none; (Journal Article)

BIO '06 visible from space?

none; (Journal Article)

Human tissue bank regulations.

van Veen; (Journal Article)

RNA synthetic biology.

Isaacs, Dwyer, Collins; (Journal Article)

Reply to Human tissue bank regulations.

none; (Journal Article)

Missing: entrepreneurial women in biotech.

Littlehales; (News)

The hermit crab solution.

Silverman; (Journal Article)

Chimeras in the crosshairs.

Scott; (Journal Article)

Transgenic plant science priorities.

Pelletier; (Journal Article)

Erratum: Corrigendum: Biocontrol genome deciphered.

Haas; (Journal Article)

Tuft's report backs FDA fast-track, but post-marketing concerns loom.

Vastag; (Journal Article)

TeGenero fiasco prompts regulatory rethink.

Sheridan; (Journal Article)

Gene prioritization through genomic data fusion.

Aerts, Lambrechts, Maity, Van Loo, Coessens, De Smet, Tranchevent, De Moor, Marynen, Hassan, Carmeliet, Moreau; (JOURNAL ARTICLE)

Building the Midwest's future.

Smaglik; (Journal Article)

Stem cell controversy to stall European tissue and cell therapy rules.

Sheridan; (Journal Article)

Building biomanufacturing capacity-the chapter and verse.

Kamarck; (Journal Article)

TGN1412-a regulator's perspective.

Schneider, Kalinke, Löwer; (Journal Article)

News in brief.

none; (Journal Article)

When the price is right.

none; (Journal Article)

In silico pharmacogenetics of warfarin metabolism.

Guo, Weller, Farrell, Cheung, Fitch, Clark, Wu, Wang, Liao, Zhang, Allard, Cheng, Nguyen, Jiang, Shafer, Usuka, Masjedizadeh, Peltz; (Journal Article)

RNA interference below the immune radar.

Sioud; (Journal Article)

Replicators lessen transcriptional silencing.

Schildkraut, Guan; (Journal Article)

US-Indian agbiotech deal under scrutiny.

Jayaraman; (Journal Article)

Small scares.

Rose; (Journal Article)

PEGging biotech growth.

Jacobs; (JOURNAL ARTICLE)

A SLAMS dunk for cancer regulators.

Kumar-Sinha, Chinnaiyan; (Journal Article)

Investors bullish in Q1.

Lawrence; (Journal Article)

Patently transparent.

none; (Journal Article)

Recent patent applications in gene therapy.

none; (Journal Article)

Reply to Transgenic plant science priorities.

none; (Journal Article)

Research highlights.

none; (Journal Article)

The human use of humanoid beings: chimeras and patent law.

Rabin; (Journal Article)

Are small biotechs still underselling themselves?

Ransom; (Journal Article)

No longer lost in translation.

Cooperman, Goldman; (Journal Article)


Nature Medicine

Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke.

Arumugam, Chan, Jo, Yilmaz, Tang, Cheng, Gleichmann, Okun, Dixit, Chigurupati, Mughal, Ouyang, Miele, Magnus, Poosala, Granger, Mattson; (JOURNAL ARTICLE)

Eradication of established tumors in mice by a combination antibody-based therapy.

Uno, Takeda, Kojima, Yoshizawa, Akiba, Mittler, Gejyo, Okumura, Yagita, Smyth; (JOURNAL ARTICLE)

Carminerin contributes to chondrocyte calcification during endochondral ossification.

Yamada, Kawano, Koshizuka, Fukuda, Yoshimura, Kamekura, Saito, Ikeda, Kawasaki, Azuma, Ikegawa, Hoshi, Chung, Nakamura, Kato, Kawaguchi; (JOURNAL ARTICLE)


Nature Genetics

Epigenetic maintenance of the vernalized state in Arabidopsis thaliana requires LIKE HETEROCHROMATIN PROTEIN 1.

Sung, He, Eshoo, Tamada, Johnson, Nakahigashi, Goto, Jacobsen, Amasino; (JOURNAL ARTICLE)

Mutations in CEP290, which encodes a centrosomal protein, cause pleiotropic forms of Joubert syndrome.

Valente, Silhavy, Brancati, Barrano, Krishnaswami, Castori, Lancaster, Boltshauser, Boccone, Al-Gazali, Fazzi, Signorini, Louie, Bellacchio, Related Disorders Study Group, Bertini, Dallapiccola, Gleeson; (JOURNAL ARTICLE)

Positional cloning of Sorcs1, a type 2 diabetes quantitative trait locus.

Clee, Yandell, Schueler, Rabaglia, Richards, Raines, Kabara, Klass, Mui, Stapleton, Gray-Keller, Young, Stoehr, Lan, Boronenkov, Raess, Flowers, Attie; (JOURNAL ARTICLE)

A common variant associated with prostate cancer in European and African populations.

Amundadottir, Sulem, Gudmundsson, Helgason, Baker, Agnarsson, Sigurdsson, Benediktsdottir, Cazier, Sainz, Jakobsdottir, Kostic, Magnusdottir, Ghosh, Agnarsson, Birgisdottir, Le Roux, Olafsdottir, Blondal, Andresdottir, Gretarsdottir, Bergthorsson, Gudbjartsson, Gylfason, Thorleifsson, Manolescu, Kristjansson, Geirsson, Isaksson, Douglas, Johansson, Bälter, Wiklund, Montie, Yu, Suarez, Ober, Cooney, Gronberg, Catalona, Einarsson, Barkardottir, Gulcher, Kong, Thorsteinsdottir, Stefansson; (JOURNAL ARTICLE)

The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4.

Sayer, Otto, O'toole, Nurnberg, Kennedy, Becker, Hennies, Helou, Attanasio, Fausett, Utsch, Khanna, Liu, Drummond, Kawakami, Kusakabe, Tsuda, Ma, Lee, Larson, Allen, Wilkinson, Nigg, Shou, Lillo, Williams, Hoppe, Kemper, Neuhaus, Parisi, Glass, Petry, Kispert, Gloy, Ganner, Walz, Zhu, Goldman, Nurnberg, Swaroop, Leroux, Hildebrandt; (JOURNAL ARTICLE)


Molecular Medicine


Proteomics

Identification of new Golgi complex specific proteins by direct organelle proteomic analysis.

Takatalo, Kouvonen, Corthals, Nyman, Rönnholm; (JOURNAL ARTICLE)

Proteomic profiling of fibroblasts reveals a modulating effect of extracellular calumenin on the organization of the actin cytoskeleton.

Ostergaard, Hansen, Vorum, Honoré; (JOURNAL ARTICLE)

Determination of the phosphorylation level and deamidation susceptibility of equine beta-casein.

Girardet, Miclo, Florent, Mollé, Gaillard; (JOURNAL ARTICLE)

A comparative proteomic evaluation of culture grown vs nodule isolated Bradyrhizobium japonicum.

Sarma, Emerich; (JOURNAL ARTICLE)

Impact of the accessory gene regulatory system (Agr) on extracellular proteins, codY expression and amino acid metabolism in Staphylococcus epidermidis.

Batzilla, Rachid, Engelmann, Hecker, Hacker, Ziebuhr; (JOURNAL ARTICLE)

Proteomic characterization of acid stress response in Synechocystis sp. PCC 6803.

Kurian, Phadwal, Mäenpää; (JOURNAL ARTICLE)

Towards a lung adenocarcinoma proteome map: Studies with SP-C/c-raf transgenic mice.

Rütters, Zürbig, Halter, Borlak; (JOURNAL ARTICLE)

Multivariate analysis of protein profiles of metal hyperaccumulator Thlaspi caerulescens accessions.

Tuomainen, Nunan, Lehesranta, Tervahauta, Hassinen, Schat, Koistinen, Auriola, McNicol, Kärenlampi; (JOURNAL ARTICLE)

In this Issue: Proteomics 10/2006.

none; (JOURNAL ARTICLE)

Product News: Proteomics 10/2006.

none; (JOURNAL ARTICLE)

Proteomic analysis of the eukaryotic parasite Encephalitozoon cuniculi (microsporidia): a reference map for proteins expressed in late sporogonial stages.

Brosson, Kuhn, Delbac, Garin, P Vivarès, Texier; (JOURNAL ARTICLE)


Nature Drug Discovery


BMC Bioinformatics

Statistical modeling of biomedical corpora: mining the Caenorhabditis Genetic Center Bibliography for genes related to life span.

Blei, Franks, Jordan, Mian; (JOURNAL ARTICLE)

Regularized binormal ROC method in disease classification using microarray data.

Ma, Song, Huang; (JOURNAL ARTICLE)

Optimizing amino acid substitution matrices with a local alignment kernel.

Saigo, Vert, Akutsu; (JOURNAL ARTICLE)

Bayesian models for pooling microarray studies with multiple sources of replications.

Conlon, Song, Liu; (JOURNAL ARTICLE)

Chaos game representation for comparison of whole genomes.

Joseph, Sasikumar; (JOURNAL ARTICLE)

Phylophenetic properties of metabolic pathway topologies as revealed by global analysis.

Zhang, Li, Skogerbo, Zhang, Zhu, Zhang, Sun, Lu, Shi, Chen; (JOURNAL ARTICLE)

Applying dynamic Bayesian networks to perturbed gene expression data.

Dojer, Gambin, Mizera, Wilczynski, Tiuryn; (JOURNAL ARTICLE)

Identification of Gene Expression Patterns using Planned Linear Contrasts.

Li, Wood, Liu, Getchell-, Getchell, Stromberg; (JOURNAL ARTICLE)

Correction of scaling mismatches in oligonucleotide microarray data.

Barenco, Stark, Brewer, Tomescu, Callard, Hubank; (JOURNAL ARTICLE)

Promoter Prediction and Annotation of Microbial Genomes Based on DNA Sequence and Structural Responses to Superhelical Stress.

Wang, Benham; (JOURNAL ARTICLE)

Identification of consensus RNA secondary structures using suffix arrays.

Anwar, Nguyen, Turcotte; (JOURNAL ARTICLE)


Bioinformatics

Observing local and global properties of metabolic pathways: "load points" and "choke points" in the metabolic networks.

Rahman, Schomburg; (JOURNAL ARTICLE)

HoSeqI: automated homologous sequence identification in gene family databases.

Arigon, Perrière, Gouy; (JOURNAL ARTICLE)

Synchronizing a multicellular system by external input: an artificial control strategy.

Wang, Chen, Aihara; (JOURNAL ARTICLE)

SCARNA: fast and accurate structural alignment of RNA sequences by matching fixed-length stem fragments.

Tabei, Tsuda, Kin, Asai; (JOURNAL ARTICLE)

PACK: Profile Analysis using Clustering and Kurtosis to find molecular classifiers in cancer.

Teschendorff, Naderi, Barbosa-Morais, Caldas; (JOURNAL ARTICLE)

BAli-Phy: simultaneous Bayesian inference of alignment and phylogeny.

Suchard, Redelings; (JOURNAL ARTICLE)

Prelude&Fugue, predicting local protein structure, early folding regions and structural weaknesses.

Kwasigroch, Rooman; (JOURNAL ARTICLE)

PROXIMO - a new algorithm to model protein complexes using data from Radical Probe Mass Spectrometry (RP-MS).

Gerega, Downard; (JOURNAL ARTICLE)


Proc Natl Acad Sci U S A

Motor cortex maps articulatory features of speech sounds.

Pulvermüller, Huss, Kherif, Moscoso Del Prado Martin, Hauk, Shtyrov; (JOURNAL ARTICLE)

The callipyge mutation enhances bidirectional long-range DLK1-GTL2 intergenic transcription in cis.

Takeda, Caiment, Smit, Hiard, Tordoir, Cockett, Georges, Charlier; (JOURNAL ARTICLE)

A common allosteric site and mechanism in caspases.

Scheer, Romanowski, Wells; (JOURNAL ARTICLE)

Evidence that feedback inhibition of NAD kinase controls responses to oxidative stress.

Grose, Joss, Velick, Roth; (JOURNAL ARTICLE)

Expression profiling reveals meiotic male germ cell mRNAs that are translationally up- and down-regulated.

Iguchi, Tobias, Hecht; (JOURNAL ARTICLE)

Production of knockout mice by random or targeted mutagenesis in spermatogonial stem cells.

Kanatsu-Shinohara, Ikawa, Takehashi, Ogonuki, Miki, Inoue, Kazuki, Lee, Toyokuni, Oshimura, Ogura, Shinohara; (JOURNAL ARTICLE)

Simvastatin promotes Th2-type responses through the induction of the chitinase family member Ym1 in dendritic cells.

Arora, Chen, Paglia, Gallagher, Allen, Vyas, Ray, Ray; (JOURNAL ARTICLE)

Probing a protein-protein interaction by in vitro evolution.

Thom, Cockroft, Buchanan, Joberty Candotti, Cohen, Lowne, Monk, Shorrock-Hart, Jermutus, Minter; (JOURNAL ARTICLE)

Multiorgan engraftment and differentiation of human cord blood CD34+Lin- cells in goats assessed by gene expression profiling.

Zeng, Chen, Baldwin, Gong, Yan, Qian, Wang, Jiang, Ren, Sun, Huang; (JOURNAL ARTICLE)

Covalent chemistry on distended proteins.

Discher, Bhasin, Johnson; (JOURNAL ARTICLE)

The real estate of cardiac signaling: Location, location, location.

George, Pitt; (JOURNAL ARTICLE)

Suppressor of cytokine signaling 3 limits protection of leukemia inhibitory factor receptor signaling against central demyelination.

Emery, Cate, Marriott, Merson, Binder, Snell, Soo, Murray, Croker, Zhang, Alexander, Cooper, Butzkueven, Kilpatrick; (JOURNAL ARTICLE)

Purkinje neuron degeneration in nervous (nr) mutant mice is mediated by a metabolic pathway involving excess tissue plasminogen activator.

Li, Ma, Teng, Zheng, Vartanian, Snyder, Sidman; (JOURNAL ARTICLE)

Light chain inclusion permits terminal B cell differentiation and does not necessarily result in autoreactivity.

Sirac, Carrion, Duchez, Comte, Cogné; (JOURNAL ARTICLE)

Transferable anticancer innate immunity in spontaneous regression/complete resistance mice.

Hicks, Riedlinger, Willingham, Alexander-Miller, Von Kap-Herr, Pettenati, Sanders, Weir, Du, Kim, Simpson, Old, Cui; (JOURNAL ARTICLE)

Oogenesis requires germ cell-specific transcriptional regulators Sohlh1 and Lhx8.

Pangas, Choi, Ballow, Zhao, Westphal, Matzuk, Rajkovic; (JOURNAL ARTICLE)

Spin glasses and fragile glasses: Statics, dynamics, and complexity.

Parisi; (JOURNAL ARTICLE)

Corticotropin-releasing hormone induces skin vascular permeability through a neurotensin-dependent process.

Donelan, Boucher, Papadopoulou, Lytinas, Papaliodis, Dobner, Theoharides; (JOURNAL ARTICLE)

Medicare prescription drug coverage: Consumer information and preferences.

Winter, Balza, Caro, Heiss, Jun, Matzkin, McFadden; (JOURNAL ARTICLE)

Pannexin 1 in erythrocytes: Function without a gap.

Locovei, Bao, Dahl; (JOURNAL ARTICLE)

Allosteric action in real time: Time-resolved crystallographic studies of a cooperative dimeric hemoglobin.

Knapp, Pahl, Srajer, Royer; (JOURNAL ARTICLE)

The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs.

Kavanagh, Guo, Dunford, Wu, Knapp, Ebetino, Rogers, Russell, Oppermann; (JOURNAL ARTICLE)

Attenuated spread of X-inactivation in an X;autosome translocation.

Popova, Tada, Takagi, Brockdorff, Nesterova; (JOURNAL ARTICLE)

A biochemical rationale for the anticancer effects of Hsp90 inhibitors: Slow, tight binding inhibition by geldanamycin and its analogues.

Gooljarsingh, Fernandes, Yan, Zhang, Grooms, Johanson, Sinnamon, Kirkpatrick, Kerrigan, Lewis, Arnone, King, Lai, Copeland, Tummino; (JOURNAL ARTICLE)

Loss of Siglec expression on T lymphocytes during human evolution.

Nguyen, Hurtado-Ziola, Gagneux, Varki; (JOURNAL ARTICLE)

Sex-specific influences of vasopressin on human social communication.

Thompson, George, Walton, Orr, Benson; (JOURNAL ARTICLE)

Low-frequency normal modes that describe allosteric transitions in biological nanomachines are robust to sequence variations.

Zheng, Brooks, Thirumalai; (JOURNAL ARTICLE)

Fluorescence resonance energy transfer in living cells reveals dynamic membrane changes in the initiation of B cell signaling.

Sohn, Tolar, Jin, Pierce; (JOURNAL ARTICLE)

REVERSION-TO-ETHYLENE SENSITIVITY1, a conserved gene that regulates ethylene receptor function in Arabidopsis.

Resnick, Wen, Shockey, Chang; (JOURNAL ARTICLE)

Ripening in the tomato Green-ripe mutant is inhibited by ectopic expression of a protein that disrupts ethylene signaling.

Barry, Giovannoni; (JOURNAL ARTICLE)

Profile of David W. McLaughlin.

Nuzzo; (JOURNAL ARTICLE)

The deprotonated guanine-cytosine base pair.

Lind, Bera, Richardson, Wheeler, Schaefer; (JOURNAL ARTICLE)

Sox10 regulates ciliary neurotrophic factor gene expression in Schwann cells.

Ito, Wiese, Funk, Chittka, Rossoll, Bömmel, Watabe, Wegner, Sendtner; (JOURNAL ARTICLE)

Nitrogen monoxide (NO)-mediated iron release from cells is linked to NO-induced glutathione efflux via multidrug resistance-associated protein 1.

Watts, Hawkins, Ponka, Richardson; (JOURNAL ARTICLE)

A model of acquired autoresistance to a potent ErbB2 tyrosine kinase inhibitor and a therapeutic strategy to prevent its onset in breast cancer.

Xia, Bacus, Hegde, Husain, Strum, Liu, Paulazzo, Lyass, Trusk, Hill, Harris, Spector; (JOURNAL ARTICLE)

Neurons produce type I interferon during viral encephalitis.

Delhaye, Paul, Blakqori, Minet, Weber, Staeheli, Michiels; (JOURNAL ARTICLE)

Stable time filtering of strongly unstable spatially extended systems.

Grote, Majda; (JOURNAL ARTICLE)

Selenoprotein deficiency accelerates prostate carcinogenesis in a transgenic model.

Diwadkar-Navsariwala, Prins, Swanson, Birch, Ray, Hedayat, Lantvit, Diamond; (JOURNAL ARTICLE)

Allelic silencing at the tumor-suppressor locus 13q14.3 suggests an epigenetic tumor-suppressor mechanism.

Mertens, Wolf, Tschuch, Mund, Kienle, Ohl, Schroeter, Lyko, Döhner, Stilgenbauer, Lichter; (JOURNAL ARTICLE)

The X chromosome is organized into a gene-rich outer rim and an internal core containing silenced nongenic sequences.

Clemson, Hall, Byron, McNeil, Lawrence; (JOURNAL ARTICLE)

Counterions between charged polymers exhibit liquid-like organization and dynamics.

Angelini, Golestanian, Coridan, Butler, Beraud, Krisch, Sinn, Schweizer, Wong; (JOURNAL ARTICLE)

Genetic variation in putative regulatory loci controlling gene expression in breast cancer.

Kristensen, Edvardsen, Tsalenko, Nordgard, Sørlie, Sharan, Vailaya, Ben-Dor, Eystein Lønning, Lien, Omholt, Syvänen, Yakhini, Børresen-Dale; (JOURNAL ARTICLE)

Highly conserved proteins that modify plant ethylene responses.

Klee; (JOURNAL ARTICLE)

Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients.

Smith, Buckley, Wu, Saenphimmachak, Hoffman, D'Argenio, Miller, Ramsey, Speert, Moskowitz, Burns, Kaul, Olson; (JOURNAL ARTICLE)

The origin of European cattle: Evidence from modern and ancient DNA.

Beja-Pereira, Caramelli, Lalueza-Fox, Vernesi, Ferrand, Casoli, Goyache, Royo, Conti, Lari, Martini, Ouragh, Magid, Atash, Zsolnai, Boscato, Triantaphylidis, Ploumi, Sineo, Mallegni, Taberlet, Erhardt, Sampietro, Bertranpetit, Barbujani, Luikart, Bertorelle; (JOURNAL ARTICLE)

The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, defines a third class of sulfatases.

Hagelueken, Adams, Wiehlmann, Widow, Kolmar, Tümmler, Heinz, Schubert; (JOURNAL ARTICLE)

Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRIP.

Ataman, Ashley, Gorczyca, Gorczyca, Mathew, Wichmann, Sigrist, Budnik; (JOURNAL ARTICLE)

siRNA in human cells selectively localizes to target RNA sites.

Berezhna, Supekova, Supek, Schultz, Deniz; (JOURNAL ARTICLE)

Development of NG2 neural progenitor cells requires Olig gene function.

Ligon, Kesari, Kitada, Sun, Arnett, Alberta, Anderson, Stiles, Rowitch; (JOURNAL ARTICLE)

Minichromosome maintenance helicase activity is controlled by N- and C-terminal motifs and requires the ATPase domain helix-2 insert.

Jenkinson, Chong; (JOURNAL ARTICLE)

Adenosine A2a blockade prevents synergy between {micro}-opiate and cannabinoid CB1 receptors and eliminates heroin-seeking behavior in addicted rats.

Yao, McFarland, Fan, Jiang, Ueda, Diamond; (JOURNAL ARTICLE)

A likelihood approach to analysis of network data.

Wiuf, Brameier, Hagberg, Stumpf; (JOURNAL ARTICLE)

Sverdlovsk revisited: Modeling human inhalation anthrax.

Wilkening; (JOURNAL ARTICLE)

Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis.

Strong, Sawaya, Wang, Phillips, Cascio, Eisenberg; (JOURNAL ARTICLE)

Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction.

Bonkowski, Rocha, Masternak, Al Regaiey, Bartke; (JOURNAL ARTICLE)

Hydrodynamic narrowing of tubes extruded from cells.

Brochard-Wyart, Borghi, Cuvelier, Nassoy; (JOURNAL ARTICLE)

Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: Implications for 22q11 deletion syndrome.

Paylor, Glaser, Mupo, Ataliotis, Spencer, Sobotka, Sparks, Choi, Oghalai, Curran, Murphy, Monks, Williams, O'donovan, Owen, Scambler, Lindsay; (JOURNAL ARTICLE)

{micro} Opioid receptor A118G polymorphism in association with striatal opioid neuropeptide gene expression in heroin abusers.

Drakenberg, Nikoshkov, Horváth, Fagergren, Gharibyan, Saarelainen, Rahman, Nylander, Bakalkin, Rajs, Keller, Hurd; (JOURNAL ARTICLE)

Activation of FIP1L1-PDGFR{alpha} requires disruption of the juxtamembrane domain of PDGFR{alpha} and is FIP1L1-independent.

Stover, Chen, Folens, Lee, Mentens, Marynen, Williams, Gilliland, Cools; (JOURNAL ARTICLE)

V1a vasopressin receptors maintain normal blood pressure by regulating circulating blood volume and baroreflex sensitivity.

Koshimizu, Nasa, Tanoue, Oikawa, Kawahara, Kiyono, Adachi, Tanaka, Kuwaki, Mori, Takeo, Okamura, Tsujimoto; (JOURNAL ARTICLE)

The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria.

Kussmaul, Hirst; (JOURNAL ARTICLE)

Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor.

Xin, Teitell, Lawson, Kwon, Mellinghoff, Witte; (JOURNAL ARTICLE)


N Engl J Med

Intermittent inhaled corticosteroids in infants with episodic wheezing.

Bisgaard, Hermansen, Loland, Halkjaer, Buchvald; (Journal Article, Randomized Controlled Trial)

Long-term outcome of renal transplantation from older donors.

Raspollini, Messerini, Taddei; (Comment, Letter)

Lenalidomide and venous thrombosis in multiple myeloma.

Knight, DeLap, Zeldis; (Letter)

Images in clinical medicine. Rotator-cuff tear.

Auethavekiat, Michet; (Case Reports, Journal Article)

NXY-059 for acute ischemic stroke.

Serebruany; (Comment, Letter)

Tumor necrosis factor alpha in refractory asthma.

Oliveri, Polosa; (Comment, Letter)

Altered bone and mineral metabolism in patients receiving imatinib mesylate.

Berman, Nicolaides, Maki, Fleisher, Chanel, Scheu, Wilson, Heller, Sauter; (Journal Article)

Claims, errors, and compensation payments in medical malpractice litigation.

Studdert, Mello, Gawande, Gandhi, Kachalia, Yoon, Puopolo, Brennan; (Journal Article)

Videos in clinical medicine. Arthrocentesis of the knee.

Thomsen, Shen, Shaffer, Setnik; (Journal Article, Review)

Long-term inhaled corticosteroids in preschool children at high risk for asthma.

Guilbert, Morgan, Zeiger, Mauger, Boehmer, Szefler, Bacharier, Lemanske, Strunk, Allen, Bloomberg, Heldt, Krawiec, Larsen, Liu, Chinchilli, Sorkness, Taussig, Martinez; (Journal Article, Multicenter Study, Randomized Controlled Trial)

Influence of graft characteristics on the outcome of kidney transplantation.

Soulillou, Giral; (Comment, Editorial)

Lineage-specific hematopoietic growth factors.

Kaushansky; (Journal Article)

Editorial independence and the Canadian Medical Association Journal.

Hoey; (Journal Article)

Intensive insulin therapy in the medical ICU.

Hammer, Dessertaine, Timsit; (Comment, Letter)

Fighting HIV--lessons from Brazil.

Okie; (Journal Article)

Coronary-artery stents.

Silverman; (Comment, Letter)

Inhaled corticosteroids for young children with wheezing.

Gold, Fuhlbrigge; (Comment, Editorial)

Images in clinical medicine. Reexpansion pulmonary edema after treatment of pneumothorax.

Tariq, Sadaf; (Journal Article)

The patient's right to safety--improving the quality of care through litigation against hospitals.

Annas; (Journal Article)

Case 5-2006: loss of vision in the right eye.

Harris; (Comment, Letter)

Case records of the Massachusetts General Hospital. Case 14-2006. A 25-year-old woman with anemia and iron overload.

Attar, Hasserjian; (Clinical Conference, Journal Article)

Regression of aortic aneurysms through pharmacologic therapy?

Verma, Lindsay; (Journal Article)

Influence of donor C3 allotype on late renal-transplantation outcome.

Brown, Kondeatis, Vaughan, Kon, Farmer, Taylor, He, Johnston, Horsfield, Janssen, Gros, Zhou, Sacks, Sheerin; (Journal Article)


J Natl Cancer Inst


Lancet

A new global immunisation vision and strategy.

Bilous, Eggers, Gasse, Jarrett, Lydon, Magan, Okwo-Bele, Salama, Vandelaer, Villeneuve, Wolfson; (Journal Article)

New focus needed for Doha trade talks.

none; (Editorial)

Unusual acute abdomen: to operate or not to operate?

Persiani, Biondi, Buccelletti, Rausei, Silveri; (Journal Article)

Global mental health-call for papers.

Patel, Prince, Saxena; (JOURNAL ARTICLE)

Book contracts and authors' rights.

Katan; (Letter)

Prenatal exposure to antiepileptic drugs.

Perucca, Tomson; (Journal Article)

Sacking of CMAJ editors.

Vogel; (Comment, Letter)

Vanished decimal point as cause of weight gain.

Wiesner, Führer, Stumvoll; (Letter)

Stillbirth rates: delivering estimates in 190 countries.

Stanton, Lawn, Rahman, Wilczynska-Ketende, Hill; (Journal Article)

Profile of Lois Jovanovic.

Sutherland, Mølsted-Pedersen; (Comment, Letter)

Greece's tobacco policy: another myth?

Vardavas, Kafatos; (Comment, Letter)

Liquid-based versus conventional cervical cytology.

Sasieni, Fielder, Rose; (Comment, Letter)

Non-invasive imaging compared with intra-arterial angiography in the diagnosis of symptomatic carotid stenosis: a meta-analysis.

Wardlaw, Chappell, Best, Wartolowska, Berry; (Journal Article)

Effect of B vitamins and genetics on success of in-vitro fertilisation: prospective cohort study.

Haggarty, McCallum, McBain, Andrews, Duthie, McNeill, Templeton, Haites, Campbell, Bhattacharya; (Journal Article)

Autopsy at the crossroads.

none; (Editorial)

Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm.

Bethony, Brooker, Albonico, Geiger, Loukas, Diemert, Hotez; (Journal Article)

Liquid-based versus conventional cervical cytology.

Biro, Hyne, Roberts, Thurloe, Bowditch; (Comment, Letter)

Liquid-based versus conventional cervical cytology.

Imrie, Colquhoun; (Comment, Letter)

Cardiac risk management in severe mental illness.

Ho, Rumsfeld; (Journal Article)

A prognostic index for AIDS-associated Kaposi's sarcoma in the era of highly active antiretroviral therapy.

Stebbing, Sanitt, Nelson, Powles, Gazzard, Bower; (Journal Article)

Dora Akunyili: scourge of Nigerian drug counterfeiters.

Harding; (News)

Road-traffic injuries: confronting disparities to address a global-health problem.

Ameratunga, Hijar, Norton; (Journal Article)

Liquid-based versus conventional cervical cytology - Authors' reply.

Davey, Barratt, Irwig, Macaskill, Saville; (LETTER)

Liquid-based versus conventional cervical cytology.

Boon; (Comment, Letter)

A secretary by any other name.

White, Perkins; (Journal Article)

Global childhood malnutrition.

none; (Editorial)

Millions in Niger facing food shortages once again.

Loewenberg; (News)

What went wrong in the natalizumab trials Comment?

Tremlett; (Comment, Letter)

1 year after The Lancet Neonatal Survival Series--was the call for action heard?

Lawn, Cousens, Darmstadt, Bhutta, Martines, Paul, Knippenberg, Fogstad; (Journal Article)

Niger welcomes largest bednet distribution in history.

Loewenberg; (News)

Poliomyelitis eradication and pandemic influenza.

Heymann, Aylward; (Journal Article)

Herodotus, the Scythes and hookworm infection.

Crubézy, Magnaval, Francfort, Ludes, Larrouy; (Journal Article)

UK medical schools and postgraduate deans.

Winyard; (Comment, Letter)

Can the chance of having twins be modified by diet?

Steinman; (Comment, Journal Article)


Expert Rev Mol Diagn