Nature

A distal enhancer and an ultraconserved exon are derived from a novel retroposon.

Bejerano, Lowe, Ahituv, King, Siepel, Salama, Rubin, James Kent, Haussler; (JOURNAL ARTICLE)

Sidelines.

none; (Journal Article)

News in brief.

none; (Journal Article)

Evolution of cooperative strategies from first principles.

Burtsev, Turchin; (Journal Article)

Making the paper: Chad Nusbaum.

none; (Journal Article)

Unique features of action potential initiation in cortical neurons.

Naundorf, Wolf, Volgushev; (Journal Article)

Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation.

Foukas, Claret, Pearce, Okkenhaug, Meek, Peskett, Sancho, Smith, Withers, Vanhaesebroeck; (JOURNAL ARTICLE)

Biomechanics: a pneumo-hydrostatic skeleton in land crabs.

Taylor, Kier; (Journal Article)

Eastern European science needs sweeping changes.

Palosz; (Comment, Letter)

Glaciology: ice-sheet plumbing in Antarctica.

Clarke; (Comment, News)

Rapid discharge connects Antarctic subglacial lakes.

Wingham, Siegert, Shepherd, Muir; (Journal Article)

Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity.

Roberts, Nanda, Havenga, Abbink, Lynch, Ewald, Liu, Thorner, Swanson, Gorgone, Lifton, Lemckert, Holterman, Chen, Dilraj, Carville, Mansfield, Goudsmit, Barouch; (JOURNAL ARTICLE)

The long road to equality.

Smaglik; (Journal Article)

A Cretaceous terrestrial snake with robust hindlimbs and a sacrum.

Apesteguía, Zaher; (Journal Article)

Breaking into business.

Baker; (Journal Article)

Drugs tests on trial.

none; (Editorial)

Research highlights.

none; (Journal Article)

Chernobyl and the future: too soon for a final diagnosis.

Williams, Baverstock; (Journal Article)

Handle with care.

Macilwain; (Journal Article)

Looking for clues.

Busuttil; (Journal Article)

A low level of extragalactic background light as revealed by gamma-rays from blazars.

Aharonian, Akhperjanian, Bazer-Bachi, Beilicke, Benbow, Berge, Bernlöhr, Boisson, Bolz, Borrel, Braun, Breitling, Brown, Chadwick, Chounet, Cornils, Costamante, Degrange, Dickinson, Djannati-Ataď, Drury, Dubus, Emmanoulopoulos, Espigat, Feinstein, Fontaine, Fuchs, Funk, Gallant, Giebels, Gillessen, Glicenstein, Goret, Hadjichristidis, Hauser, Hauser, Heinzelmann, Henri, Hermann, Hinton, Hofmann, Holleran, Horns, Jacholkowska, de Jager, Khélifi, Klages, Komin, Konopelko, Latham, Le Gallou, Lemičre, Lemoine-Goumard, Leroy, Lohse, Martin, Martineau-Huynh, Marcowith, Masterson, McComb, de Naurois, Nolan, Noutsos, Orford, Osborne, Ouchrif, Panter, Pelletier, Pita, Pühlhofer, Punch, Raubenheimer, Raue, Raux, Rayner, Reimer, Reimer, Ripken, Rob, Rolland, Rowell, Sahakian, Saugé, Schlenker, Schlickeiser, Schuster, Schwanke, Siewert, Sol, Spangler, Steenkamp, Stegmann, Tavernet, Terrier, Théoret, Tluczykont, van Eldik, Vasileiadis, Venter, Vincent, Völk, Wagner; (Journal Article)

Neuroscience: spikes too kinky in the cortex?

Gutkin, Ermentrout; (Comment, News)

Hollow centre.

Jones; (Journal Article)

Societies spurn women editors.

Dalton; (News)

Special report: counting the dead.

Peplow; (News)

Polycomb complexes repress developmental regulators in murine embryonic stem cells.

Boyer, Plath, Zeitlinger, Brambrink, Medeiros, Lee, Levine, Wernig, Tajonar, Ray, Bell, Otte, Vidal, Gifford, Young, Jaenisch; (JOURNAL ARTICLE)

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses.

Kato, Takeuchi, Sato, Yoneyama, Yamamoto, Matsui, Uematsu, Jung, Kawai, Ishii, Yamaguchi, Otsu, Tsujimura, Koh, Reis E Sousa, Matsuura, Fujita, Akira; (JOURNAL ARTICLE)

Nuclear waste: Chernobyl and the future: forward planning.

Brumfiel; (News)

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

Zody, Garber, Adams, Sharpe, Harrow, Lupski, Nicholson, Searle, Wilming, Young, Abouelleil, Allen, Bi, Bloom, Borowsky, Bugalter, Butler, Chang, Chen, Cook, Corum, Cuomo, de Jong, DeCaprio, Dewar, FitzGerald, Gilbert, Gibson, Gnerre, Goldstein, Grafham, Grocock, Hafez, Hagopian, Hart, Norman, Humphray, Jaffe, Jones, Kamal, Khodiyar, LaButti, Laird, Lehoczky, Liu, Lokyitsang, Loveland, Lui, Macdonald, Major, Matthews, Mauceli, McCarroll, Mihalev, Mudge, Nguyen, Nicol, O'Leary, Osoegawa, Schwartz, Shaw-Smith, Stankiewicz, Steward, Swarbreck, Venkataraman, Whittaker, Yang, Zimmer, Bradley, Hubbard, Birren, Rogers, Lander, Nusbaum; (Journal Article)

Mentoring award 2006.

none; (Journal Article)

Glint from tenth planet dazzles astronomers.

Giles; (News)

Science in culture: The zenith of Islamic science.

Ball; (Journal Article)

In brief.

none; (Journal Article)

A meeting of biomedical minds.

Cunningham; (Journal Article)

Modulation of intracortical synaptic potentials by presynaptic somatic membrane potential.

Shu, Hasenstaub, Duque, Yu, McCormick; (JOURNAL ARTICLE)

Loss of autophagy in the central nervous system causes neurodegeneration in mice.

Komatsu, Waguri, Chiba, Murata, Iwata, Tanida, Ueno, Koike, Uchiyama, Kominami, Tanaka; (JOURNAL ARTICLE)

Pharmaco-metabonomic phenotyping and personalized drug treatment.

Clayton, Lindon, Cloarec, Antti, Charuel, Hanton, Provost, Le Net, Baker, Walley, Everett, Nicholson; (Journal Article)

Market watch.

Wadman; (Journal Article)

Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice.

Saleh, Mathison, Wolinski, Bensinger, Fitzgerald, Droin, Ulevitch, Green, Nicholson; (Journal Article)

Wanted: cancer boss.

none; (News)

Astronomy: trouble at first light.

Madau; (Comment, News)

The perfect lover.

Di Filippo; (Journal Article)

Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex.

Ali, Roe, Vaughan, Meyer, Panaretou, Piper, Prodromou, Pearl; (Journal Article)

Lakes linked beneath Antarctic ice.

Giles; (Comment, News)

Evolution: spot on (and off).

Wray; (Comment, News)

Climate sensitivity constrained by temperature reconstructions over the past seven centuries.

Hegerl, Crowley, Hyde, Frame; (Journal Article)

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice.

Hara, Nakamura, Matsui, Yamamoto, Nakahara, Suzuki-Migishima, Yokoyama, Mishima, Saito, Okano, Mizushima; (JOURNAL ARTICLE)

Weak pairwise correlations imply strongly correlated network states in a neural population.

Schneidman, Berry, Segev, Bialek; (Journal Article)

Learning from Chernobyl.

none; (Editorial)

Reviewers peering from under a pile of 'omics' data.

Nicholson; (Letter)

Nuclear power: Chernobyl and the future: when the price is right.

Giles; (News)

Ethics: China already has clear stem-cell guidelines.

Cheng, Qiu, Deng, Zhang, Jin, Li; (Comment, Letter)

Three-dimensional structure of the myosin V inhibited state by cryoelectron tomography.

Liu, Taylor, Krementsova, Trybus, Taylor; (JOURNAL ARTICLE)

Polarons and confinement of electronic motion to two dimensions in a layered manganite.

Rřnnow, Renner, Aeppli, Kimura, Tokura; (Journal Article)

Abstractions.

none; (Journal Article)

Turning to fraud.

Rohn; (Journal Article)

Quantified: Argentina.

none; (Journal Article)

Ethics of using employees' eggs in cloning research.

Hawes, Oakley; (Comment, Letter)

Repeated morphological evolution through cis-regulatory changes in a pleiotropic gene.

Prud'homme, Gompel, Rokas, Kassner, Williams, Yeh, True, Carroll; (Journal Article)

Experimental determination of entanglement with a single measurement.

Walborn, Souto Ribeiro, Davidovich, Mintert, Buchleitner; (Journal Article)


Science

Comment on "Phylogenetic MCMC algorithms are misleading on mixtures of trees".

Ronquist, Larget, Huelsenbeck, Kadane, Simon, van der Mark; (Comment, Journal Article)

Asymmetric coevolutionary networks facilitate biodiversity maintenance.

Bascompte, Jordano, Olesen; (Journal Article)

Meeting briefs. Java Man's first tools.

Stone; (News)

Meeting briefs. When in Vietnam, build boats as the Romans do.

Stone; (News)

Women in science. Progress on hiring women science faculty members stalls at MIT.

Lawler; (News)

A plant miRNA contributes to antibacterial resistance by repressing auxin signaling.

Navarro, Dunoyer, Jay, Arnold, Dharmasiri, Estelle, Voinnet, Jones; (Journal Article)

Differential targeting of Gbetagamma-subunit signaling with small molecules.

Bonacci, Mathews, Yuan, Lehmann, Malik, Wu, Font, Bidlack, Smrcka; (Journal Article)

Drilling to Gabbro in Intact Ocean Crust.

Wilson, Teagle, Alt, Banerjee, Umino, Miyashita, Acton, Anma, Barr, Belghoul, Carlut, Christie, Coggon, Cooper, Cordier, Crispini, Durand, Einaudi, Galli, Gao, Geldmacher, Gilbert, Hayman, Herrero-Bervera, Hirano, Holter, Ingle, Jiang, Kalberkamp, Kerneklian, Koepke, Laverne, Vasquez, Maclennan, Morgan, Neo, Nichols, Park, Reichow, Sakuyama, Sano, Sandwell, Scheibner, Smith-Duque, Swift, Tartarotti, Tikku, Tominaga, Veloso, Yamasaki, Yamazaki, Ziegler; (JOURNAL ARTICLE)

Southeast Asia. Thai scientists secure royally inspired windfall.

Stone; (News)

Israel-Palestine science. Palestinian archaeology braces for a storm.

Bohannon; (News)

Ethics issues in stem cell research.

; (Letter)

Nuclear pores form de novo from both sides of the nuclear envelope.

D'Angelo, Anderson, Richard, Hetzer; (Journal Article)

Meeting briefs. Graves of the Pacific's first seafarers revealed.

Stone; (News)

Predictability and preparedness in influenza control.

Smith; (Journal Article)

Atomic-Scale Coupling of Photons to Single-Molecule Junctions.

Wu, Ogawa, Ho; (JOURNAL ARTICLE)

Science policy. NSF begins a push to measure societal impacts of research.

Mervis; (News)

Climatology. Latest forecast: stand by for a warmer, but not scorching, world.

Kerr; (News)

Stability via asynchrony in Drosophila metapopulations with low migration rates.

Dey, Joshi; (Journal Article)

Emergence of drug-resistant influenza virus: population dynamical considerations.

Regoes, Bonhoeffer; (Journal Article)

Global patterns of influenza a virus in wild birds.

Olsen, Munster, Wallensten, Waldenström, Osterhaus, Fouchier; (Journal Article)

Timing and climatic consequences of the opening of Drake Passage.

Scher, Martin; (Journal Article)

MOVERS.

none; (JOURNAL ARTICLE)

DATA POINT.

none; (JOURNAL ARTICLE)

Atomic pillar-based nanoprecipitates strengthen AlMgSi alloys.

Chen, Costan, van Huis, Xu, Zandbergen; (Journal Article)

Influenza: The State of Our Ignorance.

Ash, Roberts; (JOURNAL ARTICLE)

A one-size-fits-all flu vaccine?

Kaiser; (News)

Genetics. No longer de-identified.

McGuire, Gibbs; (Journal Article)

Israel-Palestine science. Bridging the divide in the Holy Land.

Bohannon; (News)

Host species barriers to influenza virus infections.

Kuiken, Holmes, McCauley, Rimmelzwaan, Williams, Grenfell; (Journal Article)

MOVERS.

none; (JOURNAL ARTICLE)

Chemistry. The first femtosecond in the life of a chemical reaction.

Bucksbaum; (Comment, Journal Article)

Global mineralogical and aqueous mars history derived from OMEGA/Mars Express data.

Bibring, Langevin, Mustard, Poulet, Arvidson, Gendrin, Gondet, Mangold, Pinet, Forget, Berthé, Bibring, Gendrin, Gomez, Gondet, Jouglet, Poulet, Soufflot, Vincendon, Combes, Drossart, Encrenaz, Fouchet, Merchiorri, Belluci, Altieri, Formisano, Capaccioni, Cerroni, Coradini, Fonti, Korablev, Kottsov, Ignatiev, Moroz, Titov, Zasova, Loiseau, Mangold, Pinet, Douté, Schmitt, Sotin, Hauber, Hoffmann, Jaumann, Keller, Arvidson, Mustard, Duxbury, Forget, Neukum; (Journal Article)

Materials science. Self-assembly of unusual nanoparticle crystals.

Velev; (Comment, Journal Article)

Assessing clinical trial results.

Cockerill, Norton; (Comment, Letter)

Bolometric infrared photoresponse of suspended single-walled carbon nanotube films.

Itkis, Borondics, Yu, Haddon; (Journal Article)

Visualization of Cellulose Synthase Demonstrates Functional Association with Microtubules.

Paredez, Somerville, Ehrhardt; (JOURNAL ARTICLE)

Early diagnosis of avian influenza.

Lu; (Editorial)

Israel-Palestine science. Breaking up bomb plots--and habitats?

Bohannon; (News)

Cancer research. After regime change at the National Cancer Institute.

Kaiser; (News)

Pharmacology. Hitting the hot spots of cell signaling cascades.

Tesmer; (Comment, Journal Article)

Flip-Flopping Fractional Flux Quanta.

Ortlepp, Ariando, Mielke, Verwijs, Foo, Rogalla, Uhlmann, Hilgenkamp; (JOURNAL ARTICLE)

Oseltamivir becomes plentiful--but still not cheap.

Enserink; (News)

Development. Gene-suppressing proteins reveal secrets of stem cells.

Holden; (News)

Geophysics. Opening the door to a chilly new climate regime.

Kerr; (Comment, News)

Applied physics. Laser-driven particle accelerators.

Dunne; (Comment, Journal Article)

MOVERS.

none; (JOURNAL ARTICLE)

AWARDS.

none; (JOURNAL ARTICLE)

Ecology. Mutualistic webs of species.

Thompson; (Comment, Journal Article)

Biomedical research. Court decides tissue samples belong to university, not patients.

Kaiser; (News)

Cosmology. Skewed starlight suggests particle masses changed over eons.

Cho; (News)


Nature Methods

Probing the role of multicellular organization in three-dimensional microenvironments.

Albrecht, Underhill, Wassermann, Sah, Bhatia; (JOURNAL ARTICLE)

Increasing the power of cytometry.

Jacobberger; (Journal Article)

Detection and localization of single molecular recognition events using atomic force microscopy.

Hinterdorfer, Dufręne; (Journal Article)

Gene expression: one size does not fit all.

Bonetta; (Journal Article)

A highly flexible tRNA acylation method for non-natural polypeptide synthesis.

Murakami, Ohta, Ashigai, Suga; (Journal Article)

GFP expression in muscle cells impairs actin-myosin interactions: implications for cell therapy.

Agbulut, Coirault, Niederländer, Huet, Vicart, Hagčge, Puceat, Menasché; (Journal Article)

Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling.

Krutzik, Nolan; (Journal Article)

High-throughput RNAi screening by time-lapse imaging of live human cells.

Neumann, Held, Liebel, Erfle, Rogers, Pepperkok, Ellenberg; (Journal Article)

Metabolic biotinylation of cell surface receptors for in vivo imaging.

Tannous, Grimm, Perry, Chen, Weissleder, Breakefield; (JOURNAL ARTICLE)

Reconstruction of firing rate changes across neuronal populations by temporally deconvolved Ca(2+) imaging.

Yaksi, Friedrich; (Journal Article)

Imaging activity in brain cells: deconvolution clears the haze.

Strowbridge; (Journal Article)

Delivery of short hairpin RNAs-triggers of gene silencing-into mouse embryonic stem cells.

Schaniel, Li, Schafer, Moore, Lemischka, Paddison; (Journal Article)


Nature Biotechnology

A liposome-PCR assay for the ultrasensitive detection of biological toxins.

Mason, Xu, Sheng, O'leary; (JOURNAL ARTICLE)


Nature Medicine

The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis.

Dubois, Bergeron, Kim, Dombrowski, Perreault, Fournčs, Faure, Olivier, Beauchemin, Shulman, Siminovitch, Kim, Marette; (JOURNAL ARTICLE)


Nature Genetics

Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster.

Tolhuis, Muijrers, de Wit, Teunissen, Talhout, van Steensel, van Lohuizen; (JOURNAL ARTICLE)


Molecular Medicine


Proteomics

dUTP Pyrophosphatase, its appearance in extracellular compartment may serve as a potential biomarker for N-methyl-N'-nitro-N-nitrosoguanidine exposure in mammalian cells.

Wu, Shen, Zhan, Yu; (JOURNAL ARTICLE)

Resolution and characterisation of multiple isoforms of bovine kappa-casein by 2-DE following a reversible cysteine-tagging enrichment strategy.

Holland, Deeth, Alewood; (JOURNAL ARTICLE)

The plasma membrane proteome of Saccharomyces cerevisiae and its response to the antifungal calcofluor.

Delom, Szponarski, Sommerer, Boyer, Bruneau, Rossignol, Gibrat; (JOURNAL ARTICLE)

Proteomic pattern-based analyses of light responses in Arabidopsis thaliana wild-type and photoreceptor mutants.

Kim, Cho, Park, Na, Nam; (JOURNAL ARTICLE)

Proteomic analysis of the transition from quiescent to proliferating stages in rat liver hepatectomy model.

Guo, Nian, Zhang, Huang, Tang, Xiao, He; (JOURNAL ARTICLE)

Proteins differentially expressed in response to nicotine in five rat brain regions: Identification using a 2-DE/MS-based proteomics approach.

Hwang, Li; (JOURNAL ARTICLE)

A simple and rapid protein array based method for the simultaneous detection of biowarfare agents.

Huelseweh, Ehricht, Marschall; (JOURNAL ARTICLE)

Targeted proteomics in biomarker validation: Detection and quantification of proteins using a multi-dimensional peptide separation strategy.

Immler, Greven, Reinemer; (JOURNAL ARTICLE)

Proteomics analysis of a novel compound: Cyclic RGD in breast carcinoma cell line MCF-7.

Juan, Wang, Huang, Li, Chen, Huang; (JOURNAL ARTICLE)

Optimising ovine cerebrospinal fluid preparation for two-dimensional gel electrophoresis.

Chen, Sage, Dunn, Wait, Preston; (JOURNAL ARTICLE)

Comprehensive glyco-proteomic analysis of human alpha(1)-antitrypsin and its charge isoforms.

Kolarich, Weber, Turecek, Schwarz, Altmann; (JOURNAL ARTICLE)

Comparative proteomics of glycosomes from bloodstream form and procyclic culture form Trypanosoma brucei brucei.

Colasante, Ellis, Ruppert, Voncken; (JOURNAL ARTICLE)

OUT OF CORDOBA.

Bárcena, Calvete, Moreno-López, Jorrín-Novo; (JOURNAL ARTICLE)

Proteomic analysis of the 14-3-3 family in Arabidopsis.

Fuller, Stevens, Sehnke, Ferl; (JOURNAL ARTICLE)

Changes in liver protein abundance in inbred alcohol-preferring rats due to chronic alcohol exposure, as measured through a proteomics approach.

Klouckova, Hrncirova, Mechref, Arnold, Li, McBride, Novotny; (JOURNAL ARTICLE)

Proteomic analysis of liver tissues subjected to early ischemia/reperfusion injury during human orthotopic liver transplantation.

Vascotto, Cesaratto, D'Ambrosio, Scaloni, Avellini, Paron, Baccarani, Adani, Tiribelli, Quadrifoglio, Tell; (JOURNAL ARTICLE)

Proteomic changes in hearts of kyphoscoliosis (ky) mutant mice in the absence of structural pathology: Implication for the analysis of early human heart disease.

Hou, Le Bihan, Vega-Avelaira, Coulton; (JOURNAL ARTICLE)

Proteomic analysis of protein profiles during early development of the zebrafish, Danio rerio.

Tay, Lin, Seow, Tan, Hew, Gong; (JOURNAL ARTICLE)

Proteomic analysis of rat pheochromocytoma PC12 cells.

Yang, Liu, Liu, Wang, Tong, Ji; (JOURNAL ARTICLE)

Pathway alterations during glioma progression revealed by reverse phase protein lysate arrays.

Jiang, Mircean, Shmulevich, Cogdell, Jia, Tabus, Aldape, Sawaya, Bruner, Fuller, Zhang; (JOURNAL ARTICLE)

Proteomic identification of glucocorticoid receptor interacting proteins.

Hedman, Widén, Asadi, Dinnetz, Schröder, Gustafsson, Wikström; (JOURNAL ARTICLE)

Depletion of abundant proteins from non-human primate serum for biomarker studies.

Freeman, Lull, Guilford, Vrana; (JOURNAL ARTICLE)

Identification of crystallin family proteins in vitreous body in rat endotoxin-induced uveitis: Involvement of crystallin truncation in uveitis pathogenesis.

Bahk, Lee, Jang, Choi, Lee, Chae, Song, Park, Yang, Chung; (JOURNAL ARTICLE)

Comparative proteomic analysis of hypoxia-treated and untreated human leukemic U937 cells.

Han, Xia, Song, Zheng, Chen, Zhang, Huang, Chen, Wang; (JOURNAL ARTICLE)


Nature Drug Discovery


BMC Bioinformatics

Length-dependent prediction of protein intrinsic disorder.

Peng, Radivojac, Vucetic, Dunker, Obradovic; (JOURNAL ARTICLE)

Assessment of the relationship between pre-chip and post-chip quality measures for Affymetrix GeneChip expression data.

Jones, Goldstein, Hughes, Strand, Collin, Dunnett, Kooperberg, Aragaki, Olson, Augood, Faull, Luthi-Carter, Moskvina, Hodges; (JOURNAL ARTICLE)

Correction: Versatile and declarative dynamic programming using pair algebras.

Steffen, Giegerich; (JOURNAL ARTICLE)

The statistics of identifying differentially expressed genes in Expresso and TM4: a comparison.

Sioson, Mane, Li, Sha, Heath, Bohnert, Grene; (JOURNAL ARTICLE)

PedGenie: an analysis approach for genetic association testing in extended pedigrees and genealogies of arbitrary size.

Allen-Brady, Wong, Camp; (JOURNAL ARTICLE)

An integrated system for genetic analysis.

Fiddy, Cattermole, Xie, Duan, Mott; (JOURNAL ARTICLE)

Quality Control for Terms and Definitions in Ontologies and Taxonomies.

Kohler, Munn, Ruegg, Skusa, Smith; (JOURNAL ARTICLE)

An analysis of the Sargasso Sea resource and the consequences for database composition.

Tress, Cozzetto, Tramontano, Valencia; (JOURNAL ARTICLE)


Bioinformatics


Proc Natl Acad Sci U S A

Identification of a structural motif crucial for infectivity of hepatitis B viruses.

Stoeckl, Funk, Kopitzki, Brandenburg, Oess, Will, Sirma, Hildt; (Journal Article)

Profile of C. David allis.

Downey; (Journal Article)

Mapping the Arabidopsis organelle proteome.

Dunkley, Hester, Shadforth, Runions, Weimar, Hanton, Griffin, Bessant, Brandizzi, Hawes, Watson, Dupree, Lilley; (Journal Article)

Extensive individual variation in L1 retrotransposition capability contributes to human genetic diversity.

Seleme, Vetter, Cordaux, Bastone, Batzer, Kazazian; (Journal Article)

EM measurements define the dimensions of the "30-nm" chromatin fiber: Evidence for a compact, interdigitated structure.

Robinson, Fairall, Huynh, Rhodes; (Journal Article)

Kruppel-like factor 2 (KLF2) regulates proinflammatory activation of monocytes.

Das, Kumar, Lin, Patino, Hwang, Feinberg, Majumder, Jain; (Journal Article)

Distinct genetic interactions between multiple Vegf receptors are required for development of different blood vessel types in zebrafish.

Covassin, Villefranc, Kacergis, Weinstein, Lawson; (Journal Article)

Domain architecture and structure of the bacterial cell division protein DivIB.

Robson, King; (Journal Article)

Optically directed molecular transport and 3D isoelectric positioning of amphoteric biomolecules.

Hafeman, Harkins, Witkowski, Lewis, Warmack, Brown, Thundat; (Journal Article)

Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis.

Mulligan, Ponomarev, Hitzemann, Belknap, Tabakoff, Harris, Crabbe, Blednov, Grahame, Phillips, Finn, Hoffman, Iyer, Koob, Bergeson; (Journal Article)

Evidence on the chromosomal location of centromeric DNA in Plasmodium falciparum from etoposide-mediated topoisomerase-II cleavage.

Kelly, McRobert, Baker; (Journal Article)

Site-specific proteolysis of the transcriptional coactivator HCF-1 can regulate its interaction with protein cofactors.

Vogel, Kristie; (JOURNAL ARTICLE)

A live, attenuated recombinant West Nile virus vaccine.

Monath, Liu, Kanesa-Thasan, Myers, Nichols, Deary, McCarthy, Johnson, Ermak, Shin, Arroyo, Guirakhoo, Kennedy, Ennis, Green, Bedford; (Journal Article)

ADP-ribosylating and vacuolating cytotoxin of Mycoplasma pneumoniae represents unique virulence determinant among bacterial pathogens.

Kannan, Baseman; (Journal Article)

From the Cover: Multireplicon genome architecture of Lactobacillus salivarius.

Claesson, Li, Leahy, Canchaya, van Pijkeren, Cerdeńo-Tárraga, Parkhill, Flynn, O'sullivan, Collins, Higgins, Shanahan, Fitzgerald, van Sinderen, O'toole; (Journal Article)

Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll.

Terranova, Agherbi, Boned, Meresse, Djabali; (Journal Article)

Dual roles for the trimeric G protein Go in asymmetric cell division in Drosophila.

Katanaev, Tomlinson; (Journal Article)

Evidence for a role of developmental genes in the origin of obesity and body fat distribution.

Gesta, Blüher, Yamamoto, Norris, Berndt, Kralisch, Boucher, Lewis, Kahn; (Journal Article)

Assessing the fidelity of the fossil record by using marine bivalves.

Valentine, Jablonski, Kidwell, Roy; (Journal Article)

Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2.

Kauppinen, Chan, Suh, Wiggins, Huang, Swanson; (JOURNAL ARTICLE)

Posttranslational myristoylation of caspase-activated p21-activated protein kinase 2 (PAK2) potentiates late apoptotic events.

Vilas, Corvi, Plummer, Seime, Lambkin, Berthiaume; (Journal Article)

TSC1/TSC2 and Rheb have different effects on TORC1 and TORC2 activity.

Yang, Inoki, Kim, Guan; (JOURNAL ARTICLE)

Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease.

Law, Lipska, Weickert, Hyde, Straub, Hashimoto, Harrison, Kleinman, Weinberger; (Journal Article)

DEMETER and REPRESSOR OF SILENCING 1 encode 5-methylcytosine DNA glycosylases.

Morales-Ruiz, Ortega-Galisteo, Ponferrada-Marín, Martínez-Macías, Ariza, Roldán-Arjona; (JOURNAL ARTICLE)

Differential induction of BLT receptor expression on human endothelial cells by lipopolysacharide, cytokines, and leukotriene B4.

Qiu, Johansson, Sjöström, Wan, Schröder, Palmblad, Haeggström; (JOURNAL ARTICLE)

MTA1, a transcriptional activator of breast cancer amplified sequence 3.

Gururaj, Singh, Rayala, Holm, den Hollander, Zhang, Balasenthil, Talukder, Landberg, Kumar; (Journal Article)

From the Cover: An endangered oasis of aquatic microbial biodiversity in the Chihuahuan desert.

Souza, Espinosa-Asuar, Escalante, Eguiarte, Farmer, Forney, Lloret, Rodríguez-Martínez, Soberón, Dirzo, Elser; (Journal Article)

Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade.

Bruno, Cuello; (Journal Article)

Monitoring chaperone engagement of substrates in the endoplasmic reticulum of live cells.

Snapp, Sharma, Lippincott-Schwartz, Hegde; (Journal Article)

Characterization of Su48, a centrosome protein essential for cell division.

Wang, Du, Meinkoth, Hirohashi, Zhang, Liu, Richter, Greene; (Journal Article)

FZL, an FZO-like protein in plants, is a determinant of thylakoid and chloroplast morphology.

Gao, Sage, Osteryoung; (Journal Article)

Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development.

Gavin, Torgerson, Houston, Deroos, Ho, Stray-Pedersen, Ocheltree, Greenberg, Ochs, Rudensky; (Journal Article)

Quantitative genetics of age at reproduction in wild swans: Support for antagonistic pleiotropy models of senescence.

Charmantier, Perrins, McCleery, Sheldon; (Journal Article)

Histone chaperone Asf1 is required for histone H3 lysine 56 acetylation, a modification associated with S phase in mitosis and meiosis.

Recht, Tsubota, Tanny, Diaz, Berger, Zhang, Garcia, Shabanowitz, Burlingame, Hunt, Kaufman, Allis; (JOURNAL ARTICLE)

Genomewide gain-of-function genetic screen identifies functionally active genes in mouse embryonic stem cells.

Pritsker, Ford, Jenq, Lemischka; (JOURNAL ARTICLE)

Crystal structures of {gamma}-glutamyltranspeptidase from Escherichia coli, a key enzyme in glutathione metabolism, and its reaction intermediate.

Okada, Suzuki, Wada, Kumagai, Fukuyama; (Journal Article)

Trembley's polyps go transgenic.

Steele; (Journal Article)

Archaeal mysteries of the deep revealed.

Delong; (Journal Article)

Common attributes of native-state structures of proteins, disordered proteins, and amyloid.

Hoang, Marsella, Trovato, Seno, Banavar, Maritan; (JOURNAL ARTICLE)

Homodimerization of the G protein SR{beta} in the nucleotide-free state involves proline cis/trans isomerization in the switch II region.

Schwartz, Schmidt, Brohawn, Blobel; (JOURNAL ARTICLE)

Development of bat flight: Morphologic and molecular evolution of bat wing digits.

Sears, Behringer, Rasweiler, Niswander; (Journal Article)

Arf gene loss enhances oncogenicity and limits imatinib response in mouse models of Bcr-Abl-induced acute lymphoblastic leukemia.

Williams, Roussel, Sherr; (Journal Article)

The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2'-5' oligo (A) synthetase/RNase L pathway.

Min, Krug; (JOURNAL ARTICLE)

Designing a nano-interface in a microfluidic chip to probe living cells: Challenges and perspectives.

Helmke, Minerick; (Journal Article)

Genes for the peptidoglycan synthesis pathway are essential for chloroplast division in moss.

Machida, Takechi, Sato, Chung, Kuroiwa, Takio, Seki, Shinozaki, Fujita, Hasebe, Takano; (Journal Article)

Structural plasticity of an aminoacyl-tRNA synthetase active site.

Turner, Graziano, Spraggon, Schultz; (Journal Article)

Antagonism of the prostaglandin D2 receptor 1 suppresses nicotinic acid-induced vasodilation in mice and humans.

Cheng, Wu, Wu, Sturino, Metters, Gottesdiener, Wright, Wang, O'neill, Lai, Waters; (Journal Article)

Phospholipase DZ2 plays an important role in extraplastidic galactolipid biosynthesis and phosphate recycling in Arabidopsis roots.

Cruz-Ramírez, Oropeza-Aburto, Razo-Hernández, Ramírez-Chávez, Herrera-Estrella; (Journal Article)

Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction.

Ely, Beddoe, Clements, Matthews, Purcell, Kjer-Nielsen, McCluskey, Rossjohn; (Journal Article)

From the Cover: The decline of cross-species intersensory perception in human infants.

Lewkowicz, Ghazanfar; (Journal Article)

Dysregulation of signaling pathways in CD45-deficient NK cells leads to differentially regulated cytotoxicity and cytokine production.

Hesslein, Takaki, Hermiston, Weiss, Lanier; (JOURNAL ARTICLE)


N Engl J Med

Aneurysmal subarachnoid hemorrhage.

Tritos; (Comment, Letter)

Lung Inflammation in ARDS--friend or foe?

Suter; (Comment, Editorial)

Aneurysmal subarachnoid hemorrhage.

Storrow, Wrenn; (Comment, Letter)

Aneurysmal subarachnoid hemorrhage.

de Gans, Vergouwen, Roos; (Comment, Letter)

The challenge of subgroup analyses--reporting without distorting.

Lagakos; (Comment, Journal Article)

Patent foramen ovale and unexplained stroke.

Mazzucco, Anzola; (Comment, Letter)

Images in clinical medicine. Umbilical-cord prolapse at 29 weeks' gestation.

Belfort; (Case Reports, Journal Article)

Intensive diabetes treatment and cardiovascular disease.

Weissman; (Comment, Letter)

Clinical practices. Scabies.

Chosidow; (Journal Article, Review)

Donor-derived T-cell leukemia after bone marrow transplantation.

Tamaki, Matsuoka; (Case Reports, Letter)

Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome.

Steinberg, Hudson, Goodman, Hough, Lanken, Hyzy, Thompson, Ancukiewicz; (Journal Article, Multicenter Study, Randomized Controlled Trial)

Oral ondansetron for gastroenteritis in a pediatric emergency department.

Freedman, Adler, Seshadri, Powell; (Journal Article, Randomized Controlled Trial)

Images in clinical medicine. Bird-mite infestation.

Kong, To; (Case Reports, Journal Article)

Inhaled cyclosporine in lung transplantation.

Verleden, Dupont; (Comment, Letter)

Lead shot in the appendix.

Schep, Fountain, Cox, Pesola; (Comment, Letter)

Patent foramen ovale and unexplained stroke.

Albin, Wills, Schwend; (Comment, Letter)

Private health care in Canada.

Steinbrook; (Journal Article)

Aneurysmal subarachnoid hemorrhage.

Sherlock, Agha, Thompson; (Comment, Letter)

Rotavirus vaccines.

Ruiz; (Comment, Letter)

The NIH budget and the future of biomedical research.

Loscalzo; (Journal Article)

A case of platydeoxia?

Bookman, Dryver; (Case Reports, Comment, Letter)

Case records of the Massachusetts General Hospital. Case 12-2006. A 37-year-old man with hemoptysis and a pulmonary infiltrate.

Gibbons, Branda, Shepard; (Case Reports, Clinical Conference, Journal Article)

Rotavirus vaccines.

Simonsen, Taylor, Kapikian; (Comment, Letter)

Rotavirus vaccines.

Lee; (Comment, Letter)

Rotavirus vaccines.

Molinaro, Lee, Parashar; (Comment, Letter)

Intensive diabetes treatment and cardiovascular disease.

Ross; (Comment, Letter)


J Natl Cancer Inst

Researchers target unfolded protein response in cancerous tumor growth.

Garber; (News)

Response of a KIT-positive extra-abdominal fibromatosis to imatinib mesylate and KIT genetic analysis.

Gonçalves, Monges, Yang, Palmerini, Dubreuil, Noguchi, Jacquemier, Di Stefano, Delpero, Sobol, Bertucci; (Letter)

Antitumor activity of ZSTK474, a new phosphatidylinositol 3-kinase inhibitor.

Yaguchi, Fukui, Koshimizu, Yoshimi, Matsuno, Gouda, Hirono, Yamazaki, Yamori; (Journal Article)

Stat bite: Age-specific incidence and mortality rates for ovarian cancer, 1998-2002.

none; (Journal Article)

Re: Risk of thyroid cancer after exposure to (131)I in childhood.

Scott; (Comment, Letter)

Intraperitoneal therapy for advanced ovarian cancer: will it become standard care?

Bankhead; (News)

NCCN issues first guidelines for deep vein thrombosis treatment in cancer patients.

Susman; (News)

Re: Risks of cancer and families.

Bermejo, Hemminki; (Comment, Letter)

Cancer survivorship: the interface of aging, comorbidity, and quality care.

Rowland, Yancik; (Comment, Editorial)

Long-term cancer risk among Swedish women with cosmetic breast implants: an update of a nationwide study.

McLaughlin, Lipworth, Fryzek, Ye, Tarone, Nyren; (Journal Article)

Evaluation of prostate-specific antigen declines for surrogacy in patients treated on SWOG 99-16.

Petrylak, Ankerst, Jiang, Tangen, Hussain, Lara, Jones, Taplin, Burch, Kohli, Benson, Small, Raghavan, Crawford; (Journal Article)

Assessing risk: does this patient have prostate cancer?

Carter; (Comment, Editorial)

Pregnancies, breast-feeding, and breast cancer risk in the International BRCA1/2 Carrier Cohort Study (IBCCS).

Andrieu, Goldgar, Easton, Rookus, Brohet, Antoniou, Peock, Evans, Eccles, Douglas, Nogučs, Gauthier-Villars, Chompret, Van Leeuwen, Kluijt, Benitez, Arver, Olah, Chang-Claude; (Journal Article)

Assessing prostate cancer risk: results from the Prostate Cancer Prevention Trial.

Thompson, Ankerst, Chi, Goodman, Tangen, Lucia, Feng, Parnes, Coltman; (Journal Article)

Negative Women's Health Initiative findings stir consternation, debate among researchers.

Twombly; (News)

Fourth biannual report of the Cochrane Haematological Malignancies Group.

Kober, Hülsewede, Bohlius, Engert; (Journal Article)

Surrogate endpoints: wishful thinking or reality?

Baker; (Comment, Editorial)

Functional limitations in elderly female cancer survivors.

Sweeney, Schmitz, Lazovich, Virnig, Wallace, Folsom; (Journal Article)


Lancet

Tobias' dual role heightens concern over US humanitarian aid.

Bristol; (News)

Has global HIV incidence peaked?

Shelton, Halperin, Wilson; (Comment, Journal Article)

Trial by media: dangers of misinterpretation of medical statistics.

Wright, Bradley, Sheldon, Lilford; (Letter)

Antioxidant supplementation in pre-eclampsia.

Lindheimer, Sibai; (Comment, Journal Article)

Suicide in Japan.

Crump; (Comment, Letter)

Trends in HIV-1 in young adults in south India from 2000 to 2004: a prevalence study.

Kumar, Jha, Arora, Mony, Bhatia, Millson, Dhingra, Bhattacharya, Remis, Nagelkerke; (Journal Article)

Canadian researchers respond to CMAJ crisis.

Webster; (News)

Fatal liver complications with flutamide.

Osculati, Castiglioni; (Case Reports, Letter)

BCG vaccination gets a boost.

Novelli; (Comment, Journal Article)

Advancement of global health: key messages from the Disease Control Priorities Project.

Laxminarayan, Mills, Breman, Measham, Alleyne, Claeson, Jha, Musgrove, Chow, Shahid-Salles, Jamison; (Journal Article)

HIV: compulsory testing and falling incidence?

none; (Comment, Editorial)

Cochrane and Campbell Collaborations, and health equity.

Tugwell, Petticrew, Robinson, Kristjansson, Maxwell; (Journal Article)

Effect of BCG vaccination on childhood tuberculous meningitis and miliary tuberculosis worldwide: a meta-analysis and assessment of cost-effectiveness.

Trunz, Fine, Dye; (Journal Article, Meta-Analysis)

Wasting time for wasted children: severe child undernutrition must be resolved in non-emergency settings.

Gross, Webb; (Journal Article)

Compensation for vaccine injury in Hungary.

Boncz, Sebestyén; (Comment, Letter)

The crisis in human resources for health.

none; (Editorial)

Not for sale at any price.

none; (Editorial)

Epilepsy and stigma.

Amoroso, Zwi, Somerville, Grove; (Comment, Letter)

New look at the oxyhaemoglobin dissociation curve.

Beasley, McNaughton, Robinson; (Journal Article)

A rare and reversible cause of anaemia and renal impairment.

Phanish, Andrews; (Case Reports, Journal Article)

Effect of non-invasive positive pressure ventilation (NIPPV) on mortality in patients with acute cardiogenic pulmonary oedema: a meta-analysis.

Peter, Moran, Phillips-Hughes, Graham, Bersten; (Journal Article, Meta-Analysis, Review)

Chronic disorders of consciousness.

Bernat; (Journal Article, Review)

The FIELD study.

Sirtori; (Comment, Letter)

Health inequalities and the UK Presidency of the EU.

Wilkinson, Pickett; (Journal Article)

Vitamin C and vitamin E in pregnant women at risk for pre-eclampsia (VIP trial): randomised placebo-controlled trial.

Poston, Briley, Seed, Kelly, Shennan; (Journal Article, Multicenter Study, Randomized Controlled Trial)

The FIELD study.

Föger; (Comment, Letter)

Francisco Songane: champion of maternal and child health.

Kapp; (News)